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profileYakeel Quiroz-Gaviria, Ph.D.

TitleAssistant Professor of Psychology in the Department of Psychiatry
InstitutionMassachusetts General Hospital
DepartmentPsychiatry
AddressMassachusetts General Hospital
Suite 2685
149 13th Street
Charlestown MA 02129
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Collapse Biography 
Collapse awards and honors
2013Outstanding Dissertation Award, National Academy of Neuropsychology
2013Exact, Physical and Natural Sciences Prize, Fundacion Alejandro Angel Escobar (Colombia)
2014Kavita Jain Dissertation Award, Boston University
2014Early Career Impact Award, Federation of Associations in Behavioral & Brain Sciences (FABBS)
2014 - 2019NIH Director's Early Independence Award

Collapse Overview 
Collapse overview
Dr. Quiroz completed her Ph.D. training in clinical psychology at Boston University and a fellowship in neuropsychology at Massachusetts General Hospital/Harvard Medical School.

By applying her efforts to a large family that carries a genetic mutation that causes early-onset Alzheimer’s disease (AD), Dr. Quiroz’s research has focused on characterizing brain changes that may predispose individuals to develop memory loss or dementia later in life. Her work has already provided evidence of brain abnormalities in cognitively-intact individuals at high risk for AD decades before their clinical onset. Her findings have helped the field to re-conceptualize Alzheimer as a sequence of changes that begins decades before cognitive decline, and which may be targeted by promising disease-slowing treatments at a time in which they might have their most profound effect. Her research work has resulted in several publications that have generated considerable discussion in the field, and has achieved recognition by colleagues at the regional, national, and international level.

Dr. Quiroz also has strong clinical interests in cultural neuropsychology and assessment of monolingual and bilingual Spanish-speaking patients.


Collapse Bibliographic 
Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, Giraldo M, Tirado V, Ramírez DL, Tariot PN, Dickerson BC, Sperling RA, Lopera F, Reiman EM. Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. JAMA Neurol. 2015 Aug; 72(8):912-9. PMID: 26121081; PMCID: PMC4625544.
  2. Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gutierrez Gomez M, Langois CM, Langbaum JB, Roontiva A, Thiyyagura P, Lee W, Ayutyanont N, Lopez L, Moreno S, Muñoz C, Tirado V, Acosta-Baena N, Fagan AM, Giraldo M, Garcia G, Huentelman MJ, Tariot PN, Lopera F, Reiman EM. Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study. JAMA Neurol. 2015 Mar; 72(3):316-24. PMID: 25580592; PMCID: PMC4355261.
  3. Quiroz YT, Willment KC, Castrillon G, Muniz M, Lopera F, Budson A, Stern CE. Successful Scene Encoding in Presymptomatic Early-Onset Alzheimer's Disease. J Alzheimers Dis. 2015; 47(4):955-64. PMID: 26401774; PMCID: PMC4955593.
  4. Rodriguez R, Lopera F, Alvarez A, Fernandez Y, Galan L, Quiroz Y, Bobes MA. Spectral Analysis of EEG in Familial Alzheimer's Disease with E280A Presenilin-1 Mutation Gene. Int J Alzheimers Dis. 2014; 2014:180741. PMID: 24551475; PMCID: PMC3914466.
  5. Langbaum JB, Fleisher AS, Chen K, Ayutyanont N, Lopera F, Quiroz YT, Caselli RJ, Tariot PN, Reiman EM. Ushering in the study and treatment of preclinical Alzheimer disease. Nat Rev Neurol. 2013 Jul; 9(7):371-81. PMID: 23752908; PMCID: PMC4084675.
  6. Quiroz YT, Stern CE, Reiman EM, Brickhouse M, Ruiz A, Sperling RA, Lopera F, Dickerson BC. Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers. J Neurol Neurosurg Psychiatry. 2013 May; 84(5):556-61. PMID: 23134660; PMCID: PMC3632663.
  7. Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gomez MG, Langois CM, Langbaum JB, Ayutyanont N, Roontiva A, Thiyyagura P, Lee W, Mo H, Lopez L, Moreno S, Acosta-Baena N, Giraldo M, Garcia G, Reiman RA, Huentelman MJ, Kosik KS, Tariot PN, Lopera F, Reiman EM. Florbetapir PET analysis of amyloid-ß deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study. Lancet Neurol. 2012 Dec; 11(12):1057-65. PMID: 23137949; PMCID: PMC3515078.
  8. Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, Tirado V, Munoz C, Reiman RA, Huentelman MJ, Alexander GE, Langbaum JB, Kosik KS, Tariot PN, Lopera F. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. Lancet Neurol. 2012 Dec; 11(12):1048-56. PMID: 23137948; PMCID: PMC4181671.
  9. Quiroz YT, Lopera F, Budson AE. Charting the path for early diagnosis and prevention of Alzheimer's disease. Expert Rev Neurother. 2011 Dec; 11(12):1665-7. PMID: 22091590.
    View in: PubMed
  10. Quiroz YT, Ally BA, Celone K, McKeever J, Ruiz-Rizzo AL, Lopera F, Stern CE, Budson AE. Event-related potential markers of brain changes in preclinical familial Alzheimer disease. Neurology. 2011 Aug 02; 77(5):469-75. PMID: 21775732; PMCID: PMC3146305.
  11. Reiman EM, Langbaum JB, Fleisher AS, Caselli RJ, Chen K, Ayutyanont N, Quiroz YT, Kosik KS, Lopera F, Tariot PN. Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments. J Alzheimers Dis. 2011; 26 Suppl 3:321-9. PMID: 21971471; PMCID: PMC3343739.
  12. Quiroz YT, Budson AE, Celone K, Ruiz A, Newmark R, Castrillón G, Lopera F, Stern CE. Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease. Ann Neurol. 2010 Dec; 68(6):865-75. PMID: 21194156; PMCID: PMC3175143.
  13. Bobes MA, García YF, Lopera F, Quiroz YT, Galán L, Vega M, Trujillo N, Valdes-Sosa M, Valdes-Sosa P. ERP generator anomalies in presymptomatic carriers of the Alzheimer's disease E280A PS-1 mutation. Hum Brain Mapp. 2010 Feb; 31(2):247-65. PMID: 19650138.
    View in: PubMed
  14. Schon K, Quiroz YT, Hasselmo ME, Stern CE. Greater working memory load results in greater medial temporal activity at retrieval. Cereb Cortex. 2009 Nov; 19(11):2561-71. PMID: 19224975; PMCID: PMC2758675.
  15. Palacio JD, Castellanos FX, Pineda DA, Lopera F, Arcos-Burgos M, Quiroz YT, Henao GC, Puerta IC, Ramírez DL, Rapoport JL, Bailey-Wilson J, Berg K, Muenke M. Attention-deficit/hyperactivity disorder and comorbidities in 18 Paisa Colombian multigenerational families. J Am Acad Child Adolesc Psychiatry. 2004 Dec; 43(12):1506-15. PMID: 15564820.
    View in: PubMed
  16. Quiroz-G YT. [N400: an electrophysiological measure of semantic processing]. Rev Neurol. 2003 Jun 16-30; 36(12):1176-80. PMID: 12833239.
    View in: PubMed
  17. Pineda DA, Restrepo MA, Sarmiento RJ, Gutierrez JE, Vargas SA, Quiroz YT, Hynd GW. Statistical analyses of structural magnetic resonance imaging of the head of the caudate nucleus in Colombian children with attention-deficit hyperactivity disorder. J Child Neurol. 2002 Feb; 17(2):97-105. PMID: 11952084.
    View in: PubMed
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