Harvard Catalyst Profiles

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Hao Wu, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ru H, Mi W, Zhang P, Alt FW, Schatz DG, Liao M, Wu H. DNA melting initiates the RAG catalytic pathway. Nat Struct Mol Biol. 2018 08; 25(8):732-742. PMID: 30061602; PMCID: PMC6080600.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  2. Ruan J, Xia S, Liu X, Lieberman J, Wu H. Cryo-EM structure of the gasdermin A3 membrane pore. Nature. 2018 05; 557(7703):62-67. PMID: 29695864; PMCID: PMC6007975.
    Citations: 128     Fields:    Translation:HumansAnimalsCells
  3. Mompeán M, Li W, Li J, Laage S, Siemer AB, Bozkurt G, Wu H, McDermott AE. The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex. Cell. 2018 05 17; 173(5):1244-1253.e10. PMID: 29681455; PMCID: PMC6002806.
    Citations: 81     Fields:    Translation:HumansCells
  4. Qiao Q, Wang L, Meng FL, Hwang JK, Alt FW, Wu H. AID Recognizes Structured DNA for Class Switch Recombination. Mol Cell. 2017 Aug 03; 67(3):361-373.e4. PMID: 28757211; PMCID: PMC5771415.
    Citations: 66     Fields:    Translation:HumansAnimalsCells
  5. Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, Lieberman J. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature. 2016 07 07; 535(7610):153-8. PMID: 27383986; PMCID: PMC5539988.
    Citations: 828     Fields:    Translation:HumansAnimalsCells
  6. Wu H, Fuxreiter M. The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules. Cell. 2016 May 19; 165(5):1055-1066. PMID: 27203110.
    Citations: 138     Fields:    Translation:HumansCells
  7. Ru H, Chambers MG, Fu TM, Tong AB, Liao M, Wu H. Molecular Mechanism of V(D)J Recombination from Synaptic RAG1-RAG2 Complex Structures. Cell. 2015 Nov 19; 163(5):1138-1152. PMID: 26548953.
    Citations: 87     Fields:    Translation:HumansAnimalsCells
  8. Zhang L, Shuobing C, Jianbin R, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H. Cryo-EM structure of the activated NAIP2/NLRC4 Inflammasome reveals nucleated polymerization. Science. 2015; 350:404-9.
  9. Lu A, Magupalli VG, Ruan J, Yin Q, Atianand MK, Vos MR, Schröder GF, Fitzgerald KA, Wu H, Egelman EH. Unified polymerization mechanism for the assembly of ASC-dependent inflammasomes. Cell. 2014 Mar 13; 156(6):1193-1206. PMID: 24630722.
    Citations: 484     Fields:    Translation:HumansCells
  10. Wu H. Higher-order assemblies in a new paradigm of signal transduction. Cell. 2013 Apr 11; 153(2):287-92. PMID: 23582320.
    Citations: 153     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.