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Robert Howard Goldstein, M.D.

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Tufts University School of Arts & Sciences, Medford, MABS06/2005Biochemistry
Tufts University School of Medicine, Boston, MAMD, PhD06/2012Cancer Genetics
Massachusetts General Hospital, Boston, MA06/2015Internship & Residency (Internal Medicine)
Massachusetts General Hospital, Brigham & Women's Hospital, Boston, MA06/2018Fellowship (Infectious Disease)

Throughout training, I have focused my academic pursuit on the care of the lesbian, gay, bisexual and transgender (LGBT) communities. This includes work with residency program leadership, the Division of General Internal Medicine and hospital diversity programs to incorporate training on appropriate care of LGBT patients, authoring guidelines on the topic and disseminating the material through online and in-person trainings to medical students, residents, fellows and attendings locally, as well as regional and national presentations.

My clinical practice in is focused on the care of the LGBT population. Starting in residency training, I have provided gender affirming care to transgender patients and in my fellowship training track - the HIV Clinician Educator track - I focused on the outpatient management of HIV patients, and I have specifically focused on HIV prevention and treatment in gay men. This includes training in high resolution anoscopy for the management of HPV disease, as well as a focus on pharmacologic HIV prevention strategies (post-exposure prophylaxis and pre-exposure prophylaxis).

As the Medical Director of the Transgender Health Program at Massachusetts General Hospital, I work with the Department of Medicine and hospital leadership to advance the care of transgender patients in our health system. Our work has increased awareness of transgender medicine throughout the hospital and stimulated discussion of a hospital-system approach to care of this population. We are actively pursuing the development of a transgender clinical space, with multidisciplinary teams providing gender affirming care. I will serve as the Medical Director of this clinical operation and continue to advance the care of transgender patients through innovation.

My scholarly work challenges the discrimination and stigma faced by LGBT communities within the medical system and pairs with my clinical, education and administrative work to advance care for these communities.

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. North CM, Barczak A, Goldstein RH, Healy BC, Finkelstein DM, Ding DD, Kim A, Boucau J, Shaw B, Gilbert RF, Vyas T, Reynolds Z, Siddle KJ, MacInnis BL, Regan J, Flynn JP, Choudhary MC, Vyas JM, Laskowski K, Dighe AS, Lemieux JE, Li JZ, Baden LR, Siedner MJ, Woolley AE, Sacks CA. Determining the Incidence of Asymptomatic SARS-CoV-2 Among Early Recipients of COVID-19 Vaccines (DISCOVER-COVID-19): A Prospective Cohort Study of Healthcare Workers Before, During and After Vaccination. Clin Infect Dis. 2022 Apr 09; 74(7):1275-1278. PMID: 34363462.
    Citations: 7     Fields:    
  2. Siedner MJ, Boucau J, Gilbert RF, Uddin R, Luu J, Haneuse S, Vyas T, Reynolds Z, Iyer S, Chamberlin GC, Goldstein RH, North CM, Sacks CA, Regan J, Flynn JP, Choudhary MC, Vyas JM, Barczak AK, Lemieux JE, Li JZ. Duration of viral shedding and culture positivity with postvaccination SARS-CoV-2 delta variant infections. JCI Insight. 2022 01 25; 7(2). PMID: 34871181.
    Citations: 5     Fields:    Translation:HumansCells
  3. Goldstein RH, Mehan WA, Hutchison B, Robbins GK. Case 24-2021: A 63-Year-Old Woman with Fever, Sore Throat, and Confusion. N Engl J Med. 2021 Aug 12; 385(7):641-648. PMID: 34379926.
    Citations:    Fields:    Translation:HumansCells
  4. Bunting SR, Garber SS, Goldstein RH, Calabrese SK, Ritchie TD, Batteson TJ. Health Profession Students' Awareness, Knowledge, and Confidence Regarding Preexposure Prophylaxis: Results of a National, Multidisciplinary Survey. Sex Transm Dis. 2021 01; 48(1):25-31. PMID: 32810029.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  5. Goldstein RH, Walensky RP. The Challenges Ahead With Monoclonal Antibodies: From Authorization to Access. JAMA. 2020 Dec 01; 324(21):2151-2152. PMID: 33175110.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  6. Bunting SR, Miller KW, Chappell R, Goldstein RH, DeJean O. Physician Assistant's Knowledge and Confidence Regarding Prescribing Preexposure Prophylaxis for HIV Prevention. Sex Transm Dis. 2020 Aug; 47(8):530-534. PMID: 32404857.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  7. Bunting SR, Garber SS, Goldstein RH, Ritchie TD, Batteson TJ, Keyes TJ. Student Education About Pre-exposure Prophylaxis (PrEP) Varies Between Regions of the United States. J Gen Intern Med. 2020 10; 35(10):2873-2881. PMID: 32080792.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  8. Goldstein RH, Walensky RP. Gender Parity in Clinical PrEP Trials. Reply. N Engl J Med. 2019 12 26; 381(26):2585-2586. PMID: 31881151.
    Citations:    Fields:    Translation:HumansPHPublic Health
  9. Goldstein RH, Walensky RP. Where Were the Women? Gender Parity in Clinical Trials. N Engl J Med. 2019 Dec 26; 381(26):2491-2493. PMID: 31665574.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  10. Freeman MW, Singh AK, Guidon AC, Arvikar SL, Goldstein RH, Clement NF. Case 22-2019: A 65-Year-Old Woman with Weakness, Dark Urine, and Dysphagia. N Engl J Med. 2019 Jul 18; 381(3):275-283. PMID: 31314973.
    Citations: 1     Fields:    Translation:Humans
  11. Goldstein RH, DeCaprio JA. Merkel Cell Carcinoma in the HIV-1/AIDS Patient. Cancer Treat Res. 2019; 177:211-229. PMID: 30523626.
    Citations: 5     Fields:    Translation:HumansCells
  12. Goldstein RH, Streed CG, Cahill SR. Being PrEPared - Preexposure Prophylaxis and HIV Disparities. N Engl J Med. 2018 Oct 04; 379(14):1293-1295. PMID: 30230965.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  13. LaCasce AS, Flores EJ, Goldstein RH, Sohani AR. Case 25-2017. N Engl J Med. 2017 Aug 17; 377(7):677-688. PMID: 28813220.
    Citations:    Fields:    Translation:HumansCells
  14. Sise ME, Lo GC, Goldstein RH, Allegretti AS, Masia R. Case 12-2017 - A 34-Year-Old Man with Nephropathy. N Engl J Med. 2017 04 20; 376(16):1575-1585. PMID: 28423292.
    Citations:    Fields:    Translation:Humans
  15. Sacks CA, Goldstein RH, Walensky RP. The Blood Supply and Men Who Have Sex with Men. N Engl J Med. 2017 04 13; 376(15):1486-7. PMID: 28402775.
    Citations:    Fields:    Translation:Humans
  16. Sacks CA, Goldstein RH, Walensky RP. Rethinking the Ban - The U.S. Blood Supply and Men Who Have Sex with Men. N Engl J Med. 2017 01 12; 376(2):174-177. PMID: 27959708.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  17. Numata K, Reagan MR, Goldstein RH, Rosenblatt M, Kaplan DL. Spider silk-based gene carriers for tumor cell-specific delivery. Bioconjug Chem. 2011 Aug 17; 22(8):1605-10. PMID: 21739966.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  18. Scepansky E, Goldstein R, Rosenblatt M. Preclinical orthotopic and intracardiac injection models of human breast cancer metastasis to bone and their use in drug discovery. Curr Protoc Pharmacol. 2011 Mar; Chapter 14:Unit 14.18. PMID: 21935904.
    Citations: 2     Fields:    Translation:HumansAnimals
  19. Goldstein RH, Reagan MR, Anderson K, Kaplan DL, Rosenblatt M. Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res. 2010 Dec 15; 70(24):10044-50. PMID: 21159629.
    Citations: 89     Fields:    Translation:HumansAnimalsCells
  20. Goldstein RH, Weinberg RA, Rosenblatt M. Of mice and (wo)men: mouse models of breast cancer metastasis to bone. J Bone Miner Res. 2010 Mar; 25(3):431-6. PMID: 20200984.
    Citations: 13     Fields:    Translation:HumansAnimals
  21. Liu S, Goldstein RH, Scepansky EM, Rosenblatt M. Inhibition of rho-associated kinase signaling prevents breast cancer metastasis to human bone. Cancer Res. 2009 Nov 15; 69(22):8742-51. PMID: 19887617.
    Citations: 103     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.