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JiaDe Yu, M.D.

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Biography
Virginia Commonwealth University, Richmond, VABS08/2007Chemistry
University of Virginia, Charlottesville, VAMD05/2012Medicine
Massachusetts General Hospital, Boston, MA06/2013Internship in Pediatrics
Medical College of Wisconsin, Milwaukee, WI06/2016Dermatology Residency
Children's Hospital of Philadelphia, Philadelphia, PA07/2017Fellowship in Pediatric Dermatology
Harvard School of Public Health, Boston, MASM11/2021Clinical Epidemiology

Overview

Mentoring
Available: 01/10/22, Expires: 03/01/24

Project Goal: Allergic contact dermatitis (ACD) is common in adults and children leading to significant morbidity but the gold standard diagnostic test (patch testing) is subjective. No current treatments are available and allergen avoidance is curative. The biologic underpinnings of ACD is not well understood. The goal of our project is to elucidate molecular markers that can differentiate between allergic contact dermatitis (specifically to what allergen) and other mimickers such as irritant contact dermatitis and atopic dermatitis. The knowledge learned from this research will aid in the development of novel, molecular methods of diagnosis and targeted treatments for ACD. Methods: Patients seen in the dermatology clinic will undergo tape stripping to obtain samples of their skin. The RNA from the skin samples will be extracted for further purification. The purified RNA will undergo RNA sequencing in collaboration with MGH Bioinformatics to identify key molecular signatures in ACD. Role for Student: The student will be actively involved in all steps of the project from recruitment of the patient, tape stripping, RNA purification and processing, and bioinformatic analysis. Prior skills: We look for a highly motivated and dedicated student interested in Dermatology and/or Allergy to carry this project. There is funding already available. While wet lab experience is preferred, it is not necessary and only a small component of the overall project. Bioinformatics experience is a plus but again, not necessary.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. Pediatric Dermatology Career Development Award (JiaDe Yu) Jul 1, 2019 - Jul 1, 2022
    Dermatology Foundation
    Creation of Prospective Multicenter Pediatric Allergic Contact Dermatitis Registry
    Role Description: The goal of this project is to create and install the first multicenter prospective pediatric allergic contact dermatitis registry in North America to track and better understand the prevalence and causes of allergic contact dermatitis in children.
    Role: Principal Investigator
  2. Clinical Research Award (JiaDe Yu) Apr 1, 2019 - Apr 1, 2020
    American Contact Dermatitis Society
    Identifying Acrylates in Common Medical Adhesives
    Role Description: The goal of this study is to identify the different acrylates in medical adhesives at MGH using high performance liquid chromatography.
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Young K, Yu JJ. Hand leukoderma following allergic contact dermatitis from rubber gloves in a health care worker. Contact Dermatitis. 2021 Sep; 85(3):369-370. PMID: 33835506.
    Citations:    Fields:    Translation:Humans
  2. Tam I, Schalock PC, González E, Yu J. Comparison of Allergic Contact Sensitization Prevalence Between Children and Adults: A 10-Year Retrospective Study. Dermatitis. 2020 Sep/Oct; 31(5):e55-e57. PMID: 32947464.
    Citations:    Fields:    Translation:Humans
  3. Tam I, Wang JX, Yu J. Identifying Acrylates in Medical Adhesives. Dermatitis. 2020 Jul/Aug; 31(4):e40-e42. PMID: 32665520.
    Citations: 1     Fields:    
  4. Molina GE, Smith KC, Duncan LM, Yu J. Recurrent Pruritic Papules and Reticulated Hyperpigmentation in a Young Woman: Challenge. Am J Dermatopathol. 2020 Jun; 42(6):e65. PMID: 30870166.
    Citations:    Fields:    
  5. Tam I, Schalock PC, González E, Yu J. Patch Testing Results From the Massachusetts General Hospital Contact Dermatitis Clinic, 2007-2016. Dermatitis. 2020 May/Jun; 31(3):202-208. PMID: 32209868.
    Citations: 1     Fields:    Translation:Humans
  6. Tam I, Yu J. Delayed patch test reaction to budesonide in an 8-year-old. Pediatr Dermatol. 2020 Jul; 37(4):690-691. PMID: 32301528.
    Citations:    Fields:    Translation:Humans
  7. Moustafa D, Yu J. Contact allergy to hydroperoxides of limonene and linalool in a pediatric population. J Am Acad Dermatol. 2020 Sep; 83(3):946-947. PMID: 32004642.
    Citations:    Fields:    Translation:Humans
  8. Tam I, Yu J. Allergic contact dermatitis caused by wound closure tape in a pediatric patient. Pediatr Dermatol. 2020 May; 37(3):510-511. PMID: 31975451.
    Citations:    Fields:    Translation:Humans
  9. Prasad S, Marks DH, Burns LJ, De Souza B, Flynn EA, Scheinman P, Silvestri D, Yu J, LoSicco K, Senna MM. Patch testing and contact allergen avoidance in patients with lichen planopilaris and/or frontal fibrosing alopecia: A cohort study. J Am Acad Dermatol. 2020 Aug; 83(2):659-661. PMID: 31962088.
    Citations: 1     Fields:    Translation:Humans
  10. Bai H, Tam I, Yu J. Contact Allergens in Top-Selling Textile-care Products. Dermatitis. 2020 Jan/Feb; 31(1):53-58. PMID: 31905182.
    Citations:    Fields:    Translation:Humans
  11. Teng C, Yu J, Taylor J, Rubin AI, Treat JR. Erosive pustular dermatosis of the scalp in an adolescent with near-total hair regrowth: Case report and review of the literature. Pediatr Dermatol. 2019 Sep; 36(5):697-701. PMID: 31355463.
    Citations:    Fields:    Translation:Humans
  12. Marks DH, Piantadosi AL, Patil SU, Raff A, Yu J. Successful Use of Dupilumab for Recalcitrant Atopic Dermatitis in an HIV Patient. Dermatitis. 2019 Jul/Aug; 30(4):276-277. PMID: 31261222.
    Citations: 1     Fields:    Translation:Humans
  13. Anderson LE, Treat JR, Brod BA, Yu J. "Slime" contact dermatitis: Case report and review of relevant allergens. Pediatr Dermatol. 2019 May; 36(3):335-337. PMID: 30865309.
    Citations: 1     Fields:    Translation:Humans
  14. Novosel T, Rundle CW, Yu JD, Jacob SE. Art of prevention: The importance of bath time and avoiding extended exposure to irritating and allergenic chemicals. Int J Womens Dermatol. 2019 Jul; 5(3):152-154. PMID: 31360747.
    Citations:    
  15. Garza-Mayers AC, Anderson LE, Yu J, Huang JT. Impact of dermatology consultation on the care of children with chronic graft-versus-host disease of the skin. J Am Acad Dermatol. 2019 08; 81(2):627-629. PMID: 30677461.
    Citations:    Fields:    Translation:Humans
  16. Yu J, Atwater AR, Brod B, Chen JK, Chisolm SS, Cohen DE, de la Feld S, Gaspari AA, Martin KL, Montanez-Wiscovich M, Sheehan M, Silverberg N, Lugo-Somolinos A, Thakur BK, Watsky K, Jacob SE. Pediatric Baseline Patch Test Series: Pediatric Contact Dermatitis Workgroup. Dermatitis. 2018 Jul/Aug; 29(4):206-212. PMID: 29933256.
    Citations:    Fields:    Translation:Humans
  17. Michalski B, Hackbarth DA, Wilson BD, Sokumbi O, Yu J. A Not-So-Benign Papular Eruption: Challenge. Am J Dermatopathol. 2018 Jun; 40(6):e74-e75. PMID: 29781864.
    Citations:    Fields:    
  18. Michalski B, Sokumbi O, Hackbarth DA, Wilson BD, Yu J. A Not-So-Benign Papular Eruption: Answer. Am J Dermatopathol. 2018 Jun; 40(6):452-453. PMID: 29781862.
    Citations:    Fields:    Translation:Humans
  19. Karamessinis L, Bhatti T, Yu J. Tender Nodules on the Lower Legs. JAMA Dermatol. 2018 04 01; 154(4):471-472. PMID: 29238800.
    Citations:    Fields:    Translation:Humans
  20. Yu J, Jen MV, Yan AC, Elenitsas R, Rubin AI. Angiomatoid and desmoplastic Spitz nevus presenting as a keloidal nodule. Pediatr Dermatol. 2018 Jul; 35(4):e228-e230. PMID: 29582459.
    Citations:    Fields:    Translation:Humans
  21. Yu J, Keuter T, Schilter K, Seefeldt M, Bates B, Mueller K, Drolet BA. Variability of Delivery of Timolol for the Treatment of Infantile Hemangiomas. Pediatr Dermatol. 2017 Jul; 34(4):458-460. PMID: 28660677.
    Citations: 3     Fields:    Translation:Humans
  22. Michalski B, Hackbarth DA, Wilson BD, Sokumbi O, Yu J. A Not So Benign Papular Eruption. Am J Dermatopathol. 2017 Apr 25. PMID: 28475507.
    Citations:    
  23. Yu J, Brandling-Bennett H, Co DO, Nocton JJ, Stevens AM, Chiu YE. Toxic Epidermal Necrolysis-Like Cutaneous Lupus in Pediatric Patients: A Case Series and Review. Pediatrics. 2016 06; 137(6). PMID: 27245834.
    Citations: 4     Fields:    Translation:Humans
  24. Frommelt P, Juern A, Siegel D, Holland K, Seefeldt M, Yu J, Uhing M, Wade K, Drolet B. Adverse Events in Young and Preterm Infants Receiving Topical Timolol for Infantile Hemangioma. Pediatr Dermatol. 2016 Jul; 33(4):405-14. PMID: 27246751.
    Citations: 10     Fields:    Translation:Humans
  25. Yu J, Maheshwari M, Foy AB, Calkins CM, Drolet BA. Neonatal Lumbosacral Ulceration Masking Lumbosacral and Intraspinal Hemangiomas Associated with Occult Spinal Dysraphism. J Pediatr. 2016 08; 175:211-5. PMID: 27215780.
    Citations:    Fields:    Translation:Humans
  26. Yu J, Treat J, Chaney K, Brod B. Potential Allergens in Disposable Diaper Wipes, Topical Diaper Preparations, and Disposable Diapers: Under-recognized Etiology of Pediatric Perineal Dermatitis. Dermatitis. 2016 May-Jun; 27(3):110-8. PMID: 27172304.
    Citations: 4     Fields:    Translation:HumansAnimals
  27. Yu J, Sokumbi O. Cutaneous metastasis of pleomorphic liposarcoma to the scalp: an elusive diagnosis. J Cutan Pathol. 2016 Jun; 43(6):526-530. PMID: 26968423.
    Citations: 2     Fields:    
  28. Yu J, Plaza JA, Schieke SM. Metastatic Sarcomatoid Lung Cancer: A Rare Cutaneous Spindle Cell Neoplasm. Am J Dermatopathol. 2016 Mar; 38(3):e36-9. PMID: 26894781.
    Citations: 2     Fields:    Translation:Humans
  29. Payette MJ, Weston G, Humphrey S, Yu J, Holland KE. Lichen planus and other lichenoid dermatoses: Kids are not just little people. Clin Dermatol. 2015 Nov-Dec; 33(6):631-43. PMID: 26686015.
    Citations: 6     Fields:    Translation:Humans
  30. Yu J, Siegel DH, Drolet BA, Blei F, Epstein LG, Metry D, Heyer GL. Prevalence and Clinical Characteristics of Headaches in PHACE Syndrome. J Child Neurol. 2016 Mar; 31(4):468-73. PMID: 26271792.
    Citations: 4     Fields:    Translation:Humans
  31. Yu J, Ravikumar S, Plaza JA, Troy JL, Schieke SM. Targeting the adnexal epithelium: an unusual case of syringometaplasia in a patient on vemurafenib. Am J Dermatopathol. 2015 May; 37(5):e57-60. PMID: 25839889.
    Citations:    Fields:    Translation:HumansCells
  32. Bougaki M, Searles RJ, Kida K, Yu J, Buys ES, Ichinose F. Nos3 protects against systemic inflammation and myocardial dysfunction in murine polymicrobial sepsis. Shock. 2010 Sep; 34(3):281-90. PMID: 19997049.
    Citations: 23     Fields:    Translation:AnimalsCells
  33. Minamishima S, Bougaki M, Sips PY, Yu JD, Minamishima YA, Elrod JW, Lefer DJ, Bloch KD, Ichinose F. Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice. Circulation. 2009 Sep 08; 120(10):888-96. PMID: 19704099.
    Citations: 94     Fields:    Translation:AnimalsCells
  34. Nishida T, Yu JD, Minamishima S, Sips PY, Searles RJ, Buys ES, Janssens S, Brouckaert P, Bloch KD, Ichinose F. Protective effects of nitric oxide synthase 3 and soluble guanylate cyclase on the outcome of cardiac arrest and cardiopulmonary resuscitation in mice. Crit Care Med. 2009 Jan; 37(1):256-62. PMID: 19050616.
    Citations: 13     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.