Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Joseph A. Majzoub, M.D.

Other Positions

Characterization of Oncomodulin and Its Receptor
Summer, 05/23/10 - 08/27/10
Correlations of Polymorphisms in the Glucose-6-Phosphatase Gene PASTEUR
Summer, 06/26/00 - 08/18/00

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K12DK063696 (LAFFEL, LORI M) Sep 30, 2002 - Jun 30, 2010
    Career Development in Diabetes for Pediatric Endocrinolo
    Role: Co-Principal Investigator
  2. T32DK063702 (LAFFEL, LORI M) Sep 30, 2002 - Jun 30, 2008
    Training Grant in Diabetes for Pediatric Endocrinologis*
    Role: Co-Principal Investigator
  3. P50HL067669 (KOUREMBANAS, STELLA) Sep 30, 2001 - Jul 31, 2007
    Injury, inflammation &repair: effect on developing lung
    Role: Co-Principal Investigator
  4. P01HL067669 (KOUREMBANAS, STELLA) Sep 30, 2001 - Jul 31, 2006
    Injury, inflammation &repair: effect on developing lung
    Role: Co-Principal Investigator
  5. P50HL056398 (BERNFIELD, MERTON R) Dec 1, 1996 - Nov 30, 2001
    Role: Co-Principal Investigator
This researcher has shared information about their research resources in the eagle-i Network. To update or add resource records, contact eagle-i@hms.harvard.edu.
Majzoub Lab - Mouse strains (20) and Virus strains (3)

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Edward HL, D'Gama AM, Wojcik MH, Brownstein CA, Kenna MA, Grant PE, Majzoub JA, Agrawal PB. A novel missense mutation in TFAP2B associated with Char syndrome and central diabetes insipidus. Am J Med Genet A. 2019 Jul; 179(7):1299-1303. PMID: 31012281.
  2. Stefater MA, Wolfsdorf JI, Ma NS, Majzoub JA. Glycogen storage disease presenting as Cushing syndrome. JIMD Rep. 2019 May; 47(1):17-22. PMID: 31240162.
  3. Allen BD, Liao CY, Shu J, Muglia LJ, Majzoub JA, Diaz V, Nelson JF. Hyperadrenocorticism of calorie restriction contributes to its anti-inflammatory action in mice. Aging Cell. 2019 Jun; 18(3):e12944. PMID: 30938024.
  4. Almontashiri NAM, Berry GT, Majzoub J, Peake RWA. Abnormal Glycerol Metabolism in a Child with Global Developmental Delay, Adrenal Insufficiency, and Intellectual Disability. Clin Chem. 2018 Dec; 64(12):1785-1787. PMID: 30487191.
    Citations:    Fields:    
  5. Leviton A, Allred EN, Joseph RM, O'Shea TM, Majzoub J, Kuban KCK. Behavioural dysfunctions of 10-year-old children born extremely preterm associated with corticotropin-releasing hormone expression in the placenta. Acta Paediatr. 2018 Nov; 107(11):1932-1936. PMID: 29992644.
    Citations:    Fields:    
  6. Majzoub JA, Topor LS. A New Model for Adrenarche: Inhibition of 3ß-Hydroxysteroid Dehydrogenase Type 2 by Intra-Adrenal Cortisol. Horm Res Paediatr. 2018; 89(5):311-319. PMID: 29847819.
    Citations:    Fields:    Translation:HumansAnimals
  7. James-Todd T, March MI, Seiglie J, Gupta M, Brown FM, Majzoub JA. Racial differences in neonatal hypoglycemia among very early preterm births. J Perinatol. 2018 03; 38(3):258-263. PMID: 29209031.
    Citations:    Fields:    
  8. Zhang R, Asai M, Mahoney CE, Joachim M, Shen Y, Gunner G, Majzoub JA. Loss of hypothalamic corticotropin-releasing hormone markedly reduces anxiety behaviors in mice. Mol Psychiatry. 2017 05; 22(5):733-744. PMID: 27595593.
    Citations: 6     Fields:    Translation:AnimalsCells
  9. Schneuer FJ, Bower C, Holland AJ, Tasevski V, Jamieson SE, Barker A, Lee L, Majzoub JA, Nassar N. Maternal first trimester serum levels of free-beta human chorionic gonadotrophin and male genital anomalies. Hum Reprod. 2016 08; 31(8):1895-903. PMID: 27496947.
    Citations:    Fields:    Translation:Humans
  10. Leviton A, Allred EN, Kuban KC, O'Shea TM, Paneth N, Majzoub J. Brain disorders associated with corticotropin-releasing hormone expression in the placenta among children born before the 28th week of gestation. Acta Paediatr. 2016 Jan; 105(1):e7-11. PMID: 26331704.
    Citations: 1     Fields:    Translation:Humans
  11. Herold KC, Majzoub JA, Melmed S, Pendergrass M, Schlumberger M. Endocrinology research-reflecting on the past decade and looking to the next. Nat Rev Endocrinol. 2015 Nov; 11(11):672-80. PMID: 26460340.
    Citations: 1     Fields:    Translation:Humans
  12. Thomas JL, Rajapaksha M, Mack VL, DeMars GA, Majzoub JA, Bose HS. Regulation of human 3ß-hydroxysteroid dehydrogenase type 2 by adrenal corticosteroids and product-feedback by androstenedione in human adrenarche. J Pharmacol Exp Ther. 2015 Jan; 352(1):67-76. PMID: 25355646.
    Citations: 1     Fields:    Translation:HumansCells
  13. Brownstein CA, Beggs AH, Homer N, Merriman B, Yu TW, Flannery KC, DeChene ET, Towne MC, Savage SK, Price EN, Holm IA, Luquette LJ, Lyon E, Majzoub J, Neupert P, McCallie D, Szolovits P, Willard HF, Mendelsohn NJ, Temme R, Finkel RS, Yum SW, Medne L, Sunyaev SR, Adzhubey I, Cassa CA, de Bakker PI, Duzkale H, Dworzynski P, Fairbrother W, Francioli L, Funke BH, Giovanni MA, Handsaker RE, Lage K, Lebo MS, Lek M, Leshchiner I, MacArthur DG, McLaughlin HM, Murray MF, Pers TH, Polak PP, Raychaudhuri S, Rehm HL, Soemedi R, Stitziel NO, Vestecka S, Supper J, Gugenmus C, Klocke B, Hahn A, Schubach M, Menzel M, Biskup S, Freisinger P, Deng M, Braun M, Perner S, Smith RJ, Andorf JL, Huang J, Ryckman K, Sheffield VC, Stone EM, Bair T, Black-Ziegelbein EA, Braun TA, Darbro B, DeLuca AP, Kolbe DL, Scheetz TE, Shearer AE, Sompallae R, Wang K, Bassuk AG, Edens E, Mathews K, Moore SA, Shchelochkov OA, Trapane P, Bossler A, Campbell CA, Heusel JW, Kwitek A, Maga T, Panzer K, Wassink T, Van Daele D, Azaiez H, Booth K, Meyer N, Segal MM, Williams MS, Tromp G, White P, Corsmeier D, Fitzgerald-Butt S, Herman G, Lamb-Thrush D, McBride KL, Newsom D, Pierson CR, Rakowsky AT, Maver A, Lovrecic L, Palandacic A, Peterlin B, Torkamani A, Wedell A, Huss M, Alexeyenko A, Lindvall JM, Magnusson M, Nilsson D, Stranneheim H, Taylan F, Gilissen C, Hoischen A, van Bon B, Yntema H, Nelen M, Zhang W, Sager J, Zhang L, Blair K, Kural D, Cariaso M, Lennon GG, Javed A, Agrawal S, Ng PC, Sandhu KS, Krishna S, Veeramachaneni V, Isakov O, Halperin E, Friedman E, Shomron N, Glusman G, Roach JC, Caballero J, Cox HC, Mauldin D, Ament SA, Rowen L, Richards DR, San Lucas FA, Gonzalez-Garay ML, Caskey CT, Bai Y, Huang Y, Fang F, Zhang Y, Wang Z, Barrera J, Garcia-Lobo JM, González-Lamuño D, Llorca J, Rodriguez MC, Varela I, Reese MG, De La Vega FM, Kiruluta E, Cargill M, Hart RK, Sorenson JM, Lyon GJ, Stevenson DA, Bray BE, Moore BM, Eilbeck K, Yandell M, Zhao H, Hou L, Chen X, Yan X, Chen M, Li C, Yang C, Gunel M, Li P, Kong Y, Alexander AC, Albertyn ZI, Boycott KM, Bulman DE, Gordon PM, Innes AM, Knoppers BM, Majewski J, Marshall CR, Parboosingh JS, Sawyer SL, Samuels ME, Schwartzentruber J, Kohane IS, Margulies DM. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge. Genome Biol. 2014 Mar 25; 15(3):R53. PMID: 24667040.
    Citations: 35     Fields:    Translation:Humans
  14. Freedman BD, Kempna PB, Carlone DL, Shah M, Guagliardo NA, Barrett PQ, Gomez-Sanchez CE, Majzoub JA, Breault DT. Adrenocortical zonation results from lineage conversion of differentiated zona glomerulosa cells. Dev Cell. 2013 Sep 30; 26(6):666-673. PMID: 24035414.
    Citations: 35     Fields:    Translation:AnimalsCells
  15. Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE, Ferket P, Linhart K, Ho C, Novoselova TV, Garg S, Ridderstråle M, Marcus C, Hirschhorn JN, Keogh JM, O'Rahilly S, Chan LF, Clark AJ, Farooqi IS, Majzoub JA. Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity. Science. 2013 Jul 19; 341(6143):275-8. PMID: 23869016.
    Citations: 29     Fields:    Translation:HumansAnimals
  16. Sharara-Chami RI, Zhou Y, Ebert S, Pacak K, Ozcan U, Majzoub JA. Epinephrine deficiency results in intact glucose counter-regulation, severe hepatic steatosis and possible defective autophagy in fasting mice. Int J Biochem Cell Biol. 2012 Jun; 44(6):905-13. PMID: 22405854.
    Citations: 6     Fields:    Translation:AnimalsCells
  17. Trivedi S, Joachim M, McElrath T, Kliman HJ, Allred EN, Fichorova RN, Onderdonk A, Heitor F, Chaychi L, Leviton A, Majzoub JA. Fetal-placental inflammation, but not adrenal activation, is associated with extreme preterm delivery. Am J Obstet Gynecol. 2012 Mar; 206(3):236.e1-8. PMID: 22264652.
    Citations: 11     Fields:    Translation:Humans
  18. Topor LS, Asai M, Dunn J, Majzoub JA. Cortisol stimulates secretion of dehydroepiandrosterone in human adrenocortical cells through inhibition of 3betaHSD2. J Clin Endocrinol Metab. 2011 Jan; 96(1):E31-9. PMID: 20943790.
    Citations: 13     Fields:    Translation:HumansCells
  19. Dauber A, Feldman HA, Majzoub JA. Nocturnal Dexamethasone versus Hydrocortisone for the Treatment of Children with Congenital Adrenal Hyperplasia. Int J Pediatr Endocrinol. 2010; 2010. PMID: 20871859.
    Citations: 1     
  20. Sharara-Chami RI, Joachim M, Mulcahey M, Ebert S, Majzoub JA. Effect of epinephrine deficiency on cold tolerance and on brown adipose tissue. Mol Cell Endocrinol. 2010 Oct 26; 328(1-2):34-9. PMID: 20619316.
    Citations: 6     Fields:    Translation:Animals
  21. Dauber A, Kellogg M, Majzoub JA. Monitoring of therapy in congenital adrenal hyperplasia. Clin Chem. 2010 Aug; 56(8):1245-51. PMID: 20558634.
    Citations: 13     Fields:    Translation:Humans
  22. Sharara-Chami RI, Joachim M, Pacak K, Majzoub JA. Glucocorticoid treatment--effect on adrenal medullary catecholamine production. Shock. 2010 Feb; 33(2):213-7. PMID: 19503019.
    Citations: 2     Fields:    Translation:AnimalsCells
  23. Shaw ND, Majzoub JA. Permanent Neonatal Diabetes in a Patient with a KCNJ11/Q52R Mutation Accompanied by Intermittent Hypoglycemia and Liver Failure. Int J Pediatr Endocrinol. 2009; 2009:453240. PMID: 19956803.
  24. Annesley T, Majzoub J, Hsing A, Wu A, Rockwood A, Mason D. Mass spectrometry in the clinical laboratory: how have we done, and where do we need to be? Clin Chem. 2009 Jun; 55(6):1236-9. PMID: 19395433.
    Citations: 2     Fields:    
  25. Fasting MH, Oken E, Mantzoros CS, Rich-Edwards JW, Majzoub JA, Kleinman K, Rifas-Shiman SL, Vik T, Gillman MW. Maternal levels of corticotropin-releasing hormone during pregnancy in relation to adiponectin and leptin in early childhood. J Clin Endocrinol Metab. 2009 Apr; 94(4):1409-15. PMID: 19190112.
    Citations: 8     Fields:    Translation:Humans
  26. Scribner KB, Pawlak DB, Aubin CM, Majzoub JA, Ludwig DS. Long-term effects of dietary glycemic index on adiposity, energy metabolism, and physical activity in mice. Am J Physiol Endocrinol Metab. 2008 Nov; 295(5):E1126-31. PMID: 18780772.
    Citations: 21     Fields:    Translation:AnimalsPHPublic Health
  27. Morra M, Geigenmuller U, Curran J, Rainville IR, Brennan T, Curtis J, Reichert V, Hovhannisyan H, Majzoub J, Miller DT. Genetic diagnosis of primary immune deficiencies. Immunol Allergy Clin North Am. 2008 May; 28(2):387-412, x. PMID: 18424339.
    Citations: 3     Fields:    Translation:Humans
  28. Rich-Edwards JW, Mohllajee AP, Kleinman K, Hacker MR, Majzoub J, Wright RJ, Gillman MW. Elevated midpregnancy corticotropin-releasing hormone is associated with prenatal, but not postpartum, maternal depression. J Clin Endocrinol Metab. 2008 May; 93(5):1946-51. PMID: 18303075.
    Citations: 25     Fields:    Translation:Humans
  29. Linhart KB, Majzoub JA. Pomc knockout mice have secondary hyperaldosteronism despite an absence of adrenocorticotropin. Endocrinology. 2008 Feb; 149(2):681-6. PMID: 17991729.
    Citations: 1     Fields:    Translation:Animals
  30. Majzoub JA, Srivatsa A. Diabetes insipidus: clinical and basic aspects. Pediatr Endocrinol Rev. 2006 Dec; 4 Suppl 1:60-5. PMID: 17261971.
    Citations: 7     Fields:    Translation:HumansAnimals
  31. Gillman MW, Rich-Edwards JW, Huh S, Majzoub JA, Oken E, Taveras EM, Rifas-Shiman SL. Maternal corticotropin-releasing hormone levels during pregnancy and offspring adiposity. Obesity (Silver Spring). 2006 Sep; 14(9):1647-53. PMID: 17030976.
    Citations: 23     Fields:    Translation:Humans
  32. Strong EF, Kleinman KP, Gillman MW, Clark I, Emanuel RL, Majzoub JA, Rich-Edwards JW. Measuring corticotropin-releasing hormone in pregnant women - comparing blood collection protocols for epidemiological studies. Paediatr Perinat Epidemiol. 2006 Jan; 20(1):67-71. PMID: 16420343.
    Citations: 4     Fields:    Translation:Humans
  33. McElhinney DB, Colan SD, Moran AM, Wypij D, Lin M, Majzoub JA, Crawford EC, Bartlett JM, McGrath EA, Newburger JW. Recombinant human growth hormone treatment for dilated cardiomyopathy in children. Pediatrics. 2004 Oct; 114(4):e452-8. PMID: 15466071.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  34. Silverman ES, Breault DT, Vallone J, Subramanian S, Yilmaz AD, Mathew S, Subramaniam V, Tantisira K, Pacák K, Weiss ST, Majzoub JA. Corticotropin-releasing hormone deficiency increases allergen-induced airway inflammation in a mouse model of asthma. J Allergy Clin Immunol. 2004 Oct; 114(4):747-54. PMID: 15480311.
    Citations: 17     Fields:    Translation:Animals
  35. Wise-Faberowski L, Soriano SG, Ferrari L, McManus ML, Wolfsdorf JI, Majzoub J, Scott RM, Truog R, Rockoff MA. Perioperative management of diabetes insipidus in children. J Neurosurg Anesthesiol. 2004 Jul; 16(3):220-5. PMID: 15211159.
    Citations: 3     Fields:    Translation:Humans
  36. Kubovcakova L, Tybitanclova K, Sabban EL, Majzoub J, Zorad S, Vietor I, Wagner EF, Krizanova O, Kvetnansky R. Catecholamine synthesizing enzymes and their modulation by immobilization stress in knockout mice. Ann N Y Acad Sci. 2004 Jun; 1018:458-65. PMID: 15240402.
    Citations: 4     Fields:    Translation:Animals
  37. Venihaki M, Sakihara S, Subramanian S, Dikkes P, Weninger SC, Liapakis G, Graf T, Majzoub JA. Urocortin III, a brain neuropeptide of the corticotropin-releasing hormone family: modulation by stress and attenuation of some anxiety-like behaviours. J Neuroendocrinol. 2004 May; 16(5):411-22. PMID: 15117334.
    Citations: 32     Fields:    Translation:Animals
  38. Pagan YL, Hirschhorn J, Yang B, D'Souza-Li L, Majzoub JA, Hendy GN. Maternal activating mutation of the calcium-sensing receptor: implications for calcium metabolism in the neonate. J Pediatr Endocrinol Metab. 2004 Apr; 17(4):673-7. PMID: 15198301.
    Citations:    Fields:    Translation:Humans
  39. Jeong KH, Sakihara S, Widmaier EP, Majzoub JA. Impaired leptin expression and abnormal response to fasting in corticotropin-releasing hormone-deficient mice. Endocrinology. 2004 Jul; 145(7):3174-81. PMID: 15033910.
    Citations: 4     Fields:    Translation:Animals
  40. Wise-Faberowski L, Soriano SG, Ferrari L, McManus ML, Wolfsdorf JI, Majzoub J, Scott RM, Truog R, Rockoff MA. Perioperative management of diabetes insipidus in children [corrected]. J Neurosurg Anesthesiol. 2004 Jan; 16(1):14-9. PMID: 14676564.
    Citations: 1     Fields:    Translation:Humans
  41. Brewer JA, Bethin KE, Schaefer ML, Muglia LM, Vogt SK, Weninger SC, Majzoub JA, Muglia LJ. Dissecting adrenal and behavioral responses to stress by targeted gene inactivation in mice. Stress. 2003 Jun; 6(2):121-5. PMID: 12775331.
    Citations: 3     Fields:    Translation:Animals
  42. Venihaki M, Majzoub J. Lessons from CRH knockout mice. Neuropeptides. 2002 Apr-Jun; 36(2-3):96-102. PMID: 12359501.
    Citations: 4     Fields:    Translation:Animals
  43. Gordon CM, Dougherty DD, Fischman AJ, Emans SJ, Grace E, Lamm R, Alpert NM, Majzoub JA, Rauch SL. Neural substrates of anorexia nervosa: a behavioral challenge study with positron emission tomography. J Pediatr. 2001 Jul; 139(1):51-7. PMID: 11445794.
    Citations: 17     Fields:    Translation:Humans
  44. Rich-Edwards J, Krieger N, Majzoub J, Zierler S, Lieberman E, Gillman M. Maternal experiences of racism and violence as predictors of preterm birth: rationale and study design. Paediatr Perinat Epidemiol. 2001 Jul; 15 Suppl 2:124-35. PMID: 11520405.
    Citations: 28     Fields:    Translation:Humans
  45. Muglia LJ, Jacobson L, Weninger SC, Karalis KP, Jeong K, Majzoub JA. The physiology of corticotropin-releasing hormone deficiency in mice. Peptides. 2001 May; 22(5):725-31. PMID: 11337085.
    Citations: 12     Fields:    Translation:Animals
  46. Seth KA, Majzoub JA. Repressor element silencing transcription factor/neuron-restrictive silencing factor (REST/NRSF) can act as an enhancer as well as a repressor of corticotropin-releasing hormone gene transcription. J Biol Chem. 2001 Apr 27; 276(17):13917-23. PMID: 11278361.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  47. Moran AM, Colan SD, Majzoub JA, Newburger JW. Exogenous growth hormone: a new therapy for dilated cardiomyopathy. Prog Pediatr Cardiol. 2000 Nov 04; 12(1):125-132. PMID: 11114552.
  48. Muglia LJ, Bethin KE, Jacobson L, Vogt SK, Majzoub JA. Pituitary-adrenal axis regulation in CRH-deficient mice. Endocr Res. 2000 Nov; 26(4):1057-66. PMID: 11196416.
    Citations: 7     Fields:    Translation:Animals
  49. Wohl ME, Majzoub JA. Asthma, steroids, and growth. N Engl J Med. 2000 Oct 12; 343(15):1113-4. PMID: 11027747.
    Citations:    Fields:    Translation:Humans
  50. Gordon CM, Emans SJ, DuRant RH, Mantzoros C, Grace E, Harper GP, Majzoub JA. Endocrinologic and psychological effects of short-term dexamethasone in anorexia nervosa. Eat Weight Disord. 2000 Sep; 5(3):175-82. PMID: 11082797.
    Citations:    Fields:    Translation:Humans
  51. Iwasaki Y, Oiso Y, Saito H, Majzoub JA. Effects of various mutations in the neurophysin/glycopeptide portion of the vasopressin gene on vasopressin expression in vitro. Tohoku J Exp Med. 2000 Aug; 191(4):187-202. PMID: 11038011.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  52. Venihaki M, Carrigan A, Dikkes P, Majzoub JA. Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci U S A. 2000 Jun 20; 97(13):7336-41. PMID: 10861000.
    Citations: 14     Fields:    Translation:Animals
  53. Muglia LJ, Jacobson L, Luedke C, Vogt SK, Schaefer ML, Dikkes P, Fukuda S, Sakai Y, Suda T, Majzoub JA. Corticotropin-releasing hormone links pituitary adrenocorticotropin gene expression and release during adrenal insufficiency. J Clin Invest. 2000 May; 105(9):1269-77. PMID: 10792002.
    Citations: 15     Fields:    Translation:Animals
  54. Jeong KH, Jacobson L, Paca K K, Widmaier EP, Goldstein DS, Majzoub JA. Impaired Basal and Restraint-Induced Epinephrine Secretion in Corticotropin-Releasing Hormone- Deficient Mice. Endocrinology. 2000 Mar 01; 141(3):1142-1150. PMID: 28201181.
  55. Jeong KH, Jacobson L, Pacák K, Widmaier EP, Goldstein DS, Majzoub JA. Impaired basal and restraint-induced epinephrine secretion in corticotropin-releasing hormone-deficient mice. Endocrinology. 2000 Mar; 141(3):1142-50. PMID: 10698191.
    Citations: 21     Fields:    Translation:Animals
  56. Gordon CM, Dougherty DD, Rauch SL, Emans SJ, Grace E, Lamm R, Alpert NM, Majzoub JA, Fischman AJ. Neuroanatomy of human appetitive function: A positron emission tomography investigation. Int J Eat Disord. 2000 Mar; 27(2):163-71. PMID: 10657889.
    Citations: 12     Fields:    Translation:Humans
  57. Jacobson L, Muglia LJ, Weninger SC, Pacák K, Majzoub JA. CRH deficiency impairs but does not block pituitary-adrenal responses to diverse stressors. Neuroendocrinology. 2000 Feb; 71(2):79-87. PMID: 10686522.
    Citations: 17     Fields:    Translation:Animals
  58. Weninger SC, Peters LL, Majzoub JA. Urocortin Expression in the Edinger-Westphal Nucleus Is Up-Regulated by Stress and Corticotropin-Releasing Hormone Deficiency1. Endocrinology. 2000 Jan 01; 141(1):256-263. PMID: 28201113.
  59. Weninger SC, Peters LL, Majzoub JA. Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and corticotropin-releasing hormone deficiency. Endocrinology. 2000 Jan; 141(1):256-63. PMID: 10614646.
    Citations: 21     Fields:    Translation:AnimalsCells
  60. Gudmundsson K, Majzoub JA, Bradwin G, Mandel S, Rifai N. Virilising 21-hydroxylase deficiency: timing of newborn screening and confirmatory tests can be crucial. J Pediatr Endocrinol Metab. 1999 Nov-Dec; 12(6):895-901. PMID: 10614550.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  61. Arbiser JL, Karalis K, Viswanathan A, Koike C, Anand-Apte B, Flynn E, Zetter B, Majzoub JA. Corticotropin-releasing hormone stimulates angiogenesis and epithelial tumor growth in the skin. J Invest Dermatol. 1999 Nov; 113(5):838-42. PMID: 10571742.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  62. Weninger SC, Muglia LJ, Jacobson L, Majzoub JA. CRH-deficient mice have a normal anorectic response to chronic stress. Regul Pept. 1999 Oct 22; 84(1-3):69-74. PMID: 10535410.
    Citations: 8     Fields:    Translation:Animals
  63. Weninger SC, Dunn AJ, Muglia LJ, Dikkes P, Miczek KA, Swiergiel AH, Berridge CW, Majzoub JA. Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):8283-8. PMID: 10393986.
    Citations: 40     Fields:    Translation:AnimalsCells
  64. Zurakowski D, Di Canzio J, Majzoub JA. Pediatric reference intervals for serum thyroxine, triiodothyronine, thyrotropin, and free thyroxine. Clin Chem. 1999 Jul; 45(7):1087-91. PMID: 10388488.
    Citations: 15     Fields:    Translation:HumansCells
  65. Karalis KP, Kontopoulos E, Muglia LJ, Majzoub JA. Corticotropin-releasing hormone deficiency unmasks the proinflammatory effect of epinephrine. Proc Natl Acad Sci U S A. 1999 Jun 08; 96(12):7093-7. PMID: 10359844.
    Citations: 12     Fields:    Translation:Animals
  66. Wölfl S, Martinez C, Majzoub JA. Inducible binding of cyclic adenosine 3',5'-monophosphate (cAMP)-responsive element binding protein (CREB) to a cAMP-responsive promoter in vivo. Mol Endocrinol. 1999 May; 13(5):659-69. PMID: 10319317.
    Citations: 19     Fields:    Translation:HumansCells
  67. Jeong KH, Jacobson L, Widmaier EP, Majzoub JA. Normal suppression of the reproductive axis following stress in corticotropin-releasing hormone-deficient mice. Endocrinology. 1999 Apr; 140(4):1702-8. PMID: 10098506.
    Citations: 10     Fields:    Translation:Animals
  68. Venihaki M, Majzoub JA. Animal models of CRH deficiency. Front Neuroendocrinol. 1999 Apr; 20(2):122-45. PMID: 10328987.
    Citations: 8     Fields:    Translation:HumansAnimals
  69. Ludwig DS, Majzoub JA, Al-Zahrani A, Dallal GE, Blanco I, Roberts SB. High glycemic index foods, overeating, and obesity. Pediatrics. 1999 Mar; 103(3):E26. PMID: 10049982.
    Citations: 88     Fields:    Translation:HumansCTClinical Trials
  70. Lopez MF, Dikkes P, Zurakowski D, Villa-Komaroff L, Majzoub JA. Regulation of hepatic glycogen in the insulin-like growth factor II-deficient mouse. Endocrinology. 1999 Mar; 140(3):1442-8. PMID: 10067873.
    Citations: 3     Fields:    Translation:AnimalsCells
  71. Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA. Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am J Respir Cell Mol Biol. 1999 Feb; 20(2):181-8. PMID: 9922208.
    Citations: 23     Fields:    Translation:Animals
  72. Majzoub JA, McGregor JA, Lockwood CJ, Smith R, Taggart MS, Schulkin J. A central theory of preterm and term labor: putative role for corticotropin-releasing hormone. Am J Obstet Gynecol. 1999 Jan; 180(1 Pt 3):S232-41. PMID: 9914624.
    Citations: 14     Fields:    Translation:Humans
  73. Majzoub JA, Karalis KP. Placental corticotropin-releasing hormone: function and regulation. Am J Obstet Gynecol. 1999 Jan; 180(1 Pt 3):S242-6. PMID: 9914625.
    Citations: 12     Fields:    Translation:HumansAnimals
  74. Grant FD, Ahmadi A, Hosley CM, Majzoub JA. Two novel mutations of the vasopressin gene associated with familial diabetes insipidus and identification of an asymptomatic carrier infant. J Clin Endocrinol Metab. 1998 Nov; 83(11):3958-64. PMID: 9814475.
    Citations: 1     Fields:    Translation:Humans
  75. Hanley K, Feingold KR, Kömüves LG, Elias PM, Muglia LJ, Majzoub JA, Williams ML. Glucocorticoid deficiency delays stratum corneum maturation in the fetal mouse. J Invest Dermatol. 1998 Sep; 111(3):440-4. PMID: 9740238.
    Citations: 10     Fields:    Translation:Animals
  76. Emanuel RL, Iwasaki Y, Arbiser ZK, Velez EM, Emerson CH, Majzoub JA. Vasopressin messenger ribonucleic acid regulation via the protein kinase A pathway. Endocrinology. 1998 Jun; 139(6):2831-7. PMID: 9607791.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Gordon Cm, Majzoub JA, Marsh DJ, Mulliken JB, Ponder BA, Robinson BG, Eng C. Four cases of mucosal neuroma syndrome: multiple endocrine neoplasm 2B or not 2B? J Clin Endocrinol Metab. 1998 Jan; 83(1):17-20. PMID: 9435410.
    Citations: 2     Fields:    Translation:Humans
  78. Iwasaki Y, Oiso Y, Saito H, Majzoub JA. Positive and negative regulation of the rat vasopressin gene promoter. Endocrinology. 1997 Dec; 138(12):5266-74. PMID: 9389510.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  79. Fraefel C, Jacoby DR, Lage C, Hilderbrand H, Chou JY, Alt FW, Breakefield XO, Majzoub JA. Gene transfer into hepatocytes mediated by helper virus-free HSV/AAV hybrid vectors. Mol Med. 1997 Dec; 3(12):813-25. PMID: 9440115.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  80. Gordon MS, Majzoub JA, Williams GH, Gordon MB. Sodium balance modulates thirst in normal man. Endocr Res. 1997 Nov; 23(4):377-92. PMID: 9430825.
    Citations:    Fields:    Translation:HumansCells
  81. Muglia LJ, Jacobson L, Weninger SC, Luedke CE, Bae DS, Jeong KH, Majzoub JA. Impaired diurnal adrenal rhythmicity restored by constant infusion of corticotropin-releasing hormone in corticotropin-releasing hormone-deficient mice. J Clin Invest. 1997 Jun 15; 99(12):2923-9. PMID: 9185516.
    Citations: 26     Fields:    Translation:Animals
  82. Jacobson L, Zurakowski D, Majzoub JA. Protein malnutrition increases plasma adrenocorticotropin and anterior pituitary proopiomelanocortin messenger ribonucleic acid in the rat. Endocrinology. 1997 Mar; 138(3):1048-57. PMID: 9048608.
    Citations: 10     Fields:    Translation:Animals
  83. Karalis K, Muglia LJ, Bae D, Hilderbrand H, Majzoub JA. CRH and the immune system. J Neuroimmunol. 1997 Feb; 72(2):131-6. PMID: 9042104.
    Citations: 35     Fields:    Translation:Animals
  84. Hill AG, Jacobson L, Gonzalez J, Rounds J, Majzoub JA, Wilmore DW. Chronic central nervous system exposure to interleukin-1 beta causes catabolism in the rat. Am J Physiol. 1996 Nov; 271(5 Pt 2):R1142-8. PMID: 8945946.
    Citations: 6     Fields:    Translation:Animals
  85. Karalis K, Goodwin G, Majzoub JA. Cortisol blockade of progesterone: a possible molecular mechanism involved in the initiation of human labor. Nat Med. 1996 May; 2(5):556-60. PMID: 8616715.
    Citations: 34     Fields:    Translation:HumansCells
  86. Wölfl S, Martinez C, Rich A, Majzoub JA. Transcription of the human corticotropin-releasing hormone gene in NPLC cells is correlated with Z-DNA formation. Proc Natl Acad Sci U S A. 1996 Apr 16; 93(8):3664-8. PMID: 8622993.
    Citations: 8     Fields:    Translation:HumansCells
  87. Majzoub JA, Muglia LJ. Knockout mice. N Engl J Med. 1996 Apr 04; 334(14):904-7. PMID: 8596575.
    Citations: 8     Fields:    Translation:Animals
  88. Muglia L, Jacobson L, Majzoub JA. Production of corticotropin-releasing hormone-deficient mice by targeted mutation in embryonic stem cells. Ann N Y Acad Sci. 1996 Mar 22; 780:49-59. PMID: 8602739.
    Citations: 4     Fields:    Translation:AnimalsCells
  89. Majzoub JA, Muglia LJ, Martinez C, Jacobson L. Molecular and transgenic studies of the corticotropin-releasing hormone gene. Ann N Y Acad Sci. 1995 Dec 29; 771:293-300. PMID: 8597407.
    Citations: 3     Fields:    Translation:AnimalsCells
  90. Karalis K, Majzoub JA. Regulation of placental corticotropin-releasing hormone by steroids. Possible implications in labor initiation. Ann N Y Acad Sci. 1995 Dec 29; 771:551-5. PMID: 8597430.
    Citations: 2     Fields:    Translation:HumansCells
  91. Muglia L, Jacobson L, Dikkes P, Majzoub JA. Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature. 1995 Feb 02; 373(6513):427-32. PMID: 7830793.
    Citations: 90     Fields:    Translation:AnimalsCells
  92. Muglia LJ, Jenkins NA, Gilbert DJ, Copeland NG, Majzoub JA. Expression of the mouse corticotropin-releasing hormone gene in vivo and targeted inactivation in embryonic stem cells. J Clin Invest. 1994 May; 93(5):2066-72. PMID: 8182138.
    Citations: 22     Fields:    Translation:AnimalsCells
  93. Arbiser JL, Martinez C, Arbiser ZK, Adler GK, Rosen LB, Majzoub JA. Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC. Endocrinology. 1994 Feb; 134(2):582-7. PMID: 7507828.
    Citations:    Fields:    Translation:HumansCells
  94. Emanuel RL, Robinson BG, Seely EW, Graves SW, Kohane I, Saltzman D, Barbieri R, Majzoub JA. Corticotrophin releasing hormone levels in human plasma and amniotic fluid during gestation. Clin Endocrinol (Oxf). 1994 Feb; 40(2):257-62. PMID: 8137526.
    Citations: 5     Fields:    Translation:Humans
  95. Arbiser JL, Arbiser ZK, Majzoub JA. Effects of hydroxyurea and cyclic adenosine monophosphate/protein kinase A inhibitors on the expression of the human chorionic gonadotropin alpha subunit and c-myc genes in choriocarcinoma. J Endocrinol Invest. 1993 Dec; 16(11):849-56. PMID: 8144861.
    Citations: 1     Fields:    Translation:HumansCells
  96. Hirsch AT, Majzoub JA, Ren CJ, Scales KM, Creager MA. Contribution of vasopressin to blood pressure regulation during hypovolemic hypotension in humans. J Appl Physiol (1985). 1993 Nov; 75(5):1984-8. PMID: 8307850.
    Citations: 3     Fields:    Translation:HumansCells
  97. Grant FD, Reventos J, Kawabata S, Miller M, Gordon JW, Majzoub JA. Transgenic mouse models of vasopressin expression. Hypertension. 1993 Oct; 22(4):640-5. PMID: 8406671.
    Citations:    Fields:    Translation:AnimalsCells
  98. Grant FD, Reventos J, Gordon JW, Kawabata S, Miller M, Majzoub JA. Tissue-specific expression and osmotic regulation of a rat vasopressin gene in transgenic mice. Ann N Y Acad Sci. 1993 Jul 22; 689:530-3. PMID: 8373039.
    Citations:    Fields:    Translation:AnimalsCells
  99. Grant FD, Reventos J, Gordon JW, Kawabata S, Miller M, Majzoub JA. Expression of the rat arginine vasopressin gene in transgenic mice. Mol Endocrinol. 1993 May; 7(5):659-67. PMID: 8100353.
    Citations: 7     Fields:    Translation:Animals
  100. Arbiser JL, Arbiser ZK, Majzoub JA. Differential regulation of choriocarcinoma gene expression by DNA synthesis inhibitors. Endocr J. 1993 Apr; 40(2):263-8. PMID: 7951513.
    Citations: 3     Fields:    Translation:HumansCells
  101. Majzoub JA, Emanuel R, Adler G, Martinez C, Robinson B, Wittert G. Second messenger regulation of mRNA for corticotropin-releasing factor. Ciba Found Symp. 1993; 172:30-43; discussion 43-58. PMID: 8491092.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  102. Emanuel RL, Girard DM, Thull DL, Majzoub JA. Regulated expression of vasopressin gene by cAMP and phorbol ester in primary rat fetal hypothalamic cultures. Mol Cell Endocrinol. 1992 Jul; 86(1-2):29-36. PMID: 1355050.
    Citations: 3     Fields:    Translation:AnimalsCells
  103. Rosen LB, Majzoub JA, Adler GK. Effects of glucocorticoid on corticotropin-releasing hormone gene regulation by second messenger pathways in NPLC and AtT-20 cells. Endocrinology. 1992 Apr; 130(4):2237-44. PMID: 1547737.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  104. Adler GK, Rosen LB, Fiandaca MJ, Majzoub JA. Protein kinase-C activation increases the quantity and poly(A) tail length of corticotropin-releasing hormone messenger RNA in NPLC cells. Mol Endocrinol. 1992 Mar; 6(3):476-84. PMID: 1350054.
    Citations: 7     Fields:    Translation:HumansCells
  105. Robinson BG, Mealy K, Wilmore DW, Majzoub JA. The effect of insulin-induced hypoglycemia on gene expression in the hypothalamic-pituitary-adrenal axis of the rat. Endocrinology. 1992 Feb; 130(2):920-5. PMID: 1310284.
    Citations: 2     Fields:    Translation:Animals
  106. Arbiser JL, Arbiser ZK, Majzoub JA. Regulation of gene expression in choriocarcinoma by methotrexate and hydroxyurea. Endocrinology. 1991 Feb; 128(2):972-8. PMID: 1989875.
    Citations: 6     Fields:    Translation:HumansCells
  107. Michie HR, Majzoub JA, O'Dwyer ST, Revhaug A, Wilmore DW. Both cyclooxygenase-dependent and cyclooxygenase-independent pathways mediate the neuroendocrine response in humans. Surgery. 1990 Aug; 108(2):254-9; discussion 259-61. PMID: 2116676.
    Citations: 2     Fields:    Translation:HumansCells
  108. Emanuel RL, Girard DM, Thull DL, Majzoub JA. Second messengers involved in the regulation of corticotropin-releasing hormone mRNA and peptide in cultured rat fetal hypothalamic primary cultures. Endocrinology. 1990 Jun; 126(6):3016-21. PMID: 2351106.
    Citations: 10     Fields:    Translation:AnimalsCells
  109. Adler GK, Smas CM, Fiandaca M, Frim DM, Majzoub JA. Regulated expression of the human corticotropin releasing hormone gene by cyclic AMP. Mol Cell Endocrinol. 1990 Apr 17; 70(2):165-74. PMID: 2161364.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  110. Mealy K, Robinson B, Millette CF, Majzoub J, Wilmore DW. The testicular effects of tumor necrosis factor. Ann Surg. 1990 Apr; 211(4):470-5. PMID: 2108622.
    Citations: 7     Fields:    Translation:AnimalsCells
  111. Frim DM, Robinson BG, Pasieka KB, Majzoub JA. Differential regulation of corticotropin-releasing hormone mRNA in rat brain. Am J Physiol. 1990 Apr; 258(4 Pt 1):E686-92. PMID: 2333962.
    Citations: 9     Fields:    Translation:Animals
  112. Emanuel RL, Thull DL, Girard DM, Majzoub JA. Developmental expression of corticotropin releasing hormone messenger RNA and peptide in rat hypothalamus. Peptides. 1989 Nov-Dec; 10(6):1165-9. PMID: 2576125.
    Citations:    Fields:    Translation:Animals
  113. Hirsch AT, Dzau VJ, Majzoub JA, Creager MA. Vasopressin-mediated forearm vasodilation in normal humans. Evidence for a vascular vasopressin V2 receptor. J Clin Invest. 1989 Aug; 84(2):418-26. PMID: 2527249.
    Citations: 13     Fields:    Translation:Humans
  114. Graves SW, Adler G, Stuenkel C, Sharma K, Brena A, Majzoub J. Increases in plasma digitalis-like factor activity during insulin-induced hypoglycemia. Neuroendocrinology. 1989 Jun; 49(6):586-91. PMID: 2671776.
    Citations:    Fields:    Translation:Humans
  115. Robinson BG, Arbiser JL, Emanuel RL, Majzoub JA. Species-specific placental corticotropin releasing hormone messenger RNA and peptide expression. Mol Cell Endocrinol. 1989 Apr; 62(2):337-41. PMID: 2787253.
    Citations: 12     Fields:    Translation:HumansAnimals
  116. Robinson BG, D'Angio LA, Pasieka KB, Majzoub JA. Preprocorticotropin releasing hormone: cDNA sequence and in vitro processing. Mol Cell Endocrinol. 1989 Feb; 61(2):175-80. PMID: 2783917.
    Citations: 4     Fields:    Translation:HumansCells
  117. Robinson BG, Frim DM, Schwartz WJ, Majzoub JA. Vasopressin mRNA in the suprachiasmatic nuclei: daily regulation of polyadenylate tail length. Science. 1988 Jul 15; 241(4863):342-4. PMID: 3388044.
    Citations: 31     Fields:    Translation:Animals
  118. Robinson BG, Emanuel RL, Frim DM, Majzoub JA. Glucocorticoid stimulates expression of corticotropin-releasing hormone gene in human placenta. Proc Natl Acad Sci U S A. 1988 Jul; 85(14):5244-8. PMID: 2839838.
    Citations: 44     Fields:    Translation:HumansCells
  119. Frim DM, Emanuel RL, Robinson BG, Smas CM, Adler GK, Majzoub JA. Characterization and gestational regulation of corticotropin-releasing hormone messenger RNA in human placenta. J Clin Invest. 1988 Jul; 82(1):287-92. PMID: 3260606.
    Citations: 17     Fields:    Translation:HumansCells
  120. Carrazana EJ, Pasieka KB, Majzoub JA. The vasopressin mRNA poly(A) tract is unusually long and increases during stimulation of vasopressin gene expression in vivo. Mol Cell Biol. 1988 Jun; 8(6):2267-74. PMID: 2841576.
    Citations: 29     Fields:    Translation:AnimalsCells
  121. Caulfield MP, Duong LT, O'Brien R, Majzoub JA, Rosenblatt M. A chemically synthesized radiolabeled signal peptide: design, preparation, and biological evaluation of an iodinated analog of preproparathyroid hormone. Mol Endocrinol. 1988 May; 2(5):452-8. PMID: 3419434.
    Citations:    Fields:    Translation:HumansCells
  122. Adler GK, Smas CM, Majzoub JA. Expression and dexamethasone regulation of the human corticotropin-releasing hormone gene in a mouse anterior pituitary cell line. J Biol Chem. 1988 Apr 25; 263(12):5846-52. PMID: 2965706.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  123. Arbiser JL, Morton CC, Bruns GA, Majzoub JA. Human corticotropin releasing hormone gene is located on the long arm of chromosome 8. Cytogenet Cell Genet. 1988; 47(3):113-6. PMID: 3259914.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  124. Nabel EG, Colucci WS, Lilly LS, Cutler SS, Majzoub JA, St John Sutton MG, Dzau VJ, Creager MA. Relationship of cardiac chamber volume to baroreflex activity in normal humans. J Clin Endocrinol Metab. 1987 Sep; 65(3):475-81. PMID: 3624410.
    Citations:    Fields:    Translation:HumansCells
  125. Adler GK, Majzoub JA. Influence of infused hypertonic saline on the response to insulin-induced hypoglycemia in man. J Clin Endocrinol Metab. 1987 Jul; 65(1):116-21. PMID: 3034950.
    Citations: 2     Fields:    Translation:Humans
  126. Majzoub JA, Carrazana EJ, Shulman JS, Baker KJ, Emanuel RL. Defective regulation of vasopressin gene expression in Brattleboro rats. Am J Physiol. 1987 May; 252(5 Pt 1):E637-42. PMID: 3578512.
    Citations: 6     Fields:    Translation:Animals
  127. Majzoub JA, Pappey A, Burg R, Habener JF. Vasopressin gene is expressed at low levels in the hypothalamus of the Brattleboro rat. Proc Natl Acad Sci U S A. 1984 Sep; 81(17):5296-9. PMID: 6591192.
    Citations: 5     Fields:    Translation:AnimalsCells
  128. Majzoub JA, Rich A, van Boom J, Habener JF. Vasopressin and oxytocin mRNA regulation in the rat assessed by hybridization with synthetic oligonucleotides. J Biol Chem. 1983 Dec 10; 258(23):14061-4. PMID: 6689019.
    Citations: 14     Fields:    Translation:AnimalsCells
  129. Majzoub JA, Dee PC, Habener JF. Cellular and cell-free processing of parathyroid secretory proteins. J Biol Chem. 1982 Apr 10; 257(7):3581-8. PMID: 7061498.
    Citations: 3     Fields:    Translation:AnimalsCells
  130. Majzoub JA, Rosenblatt M, Fennick B, Maunus R, Kronenberg HM, Potts JT, Habener JF. Synthetic pre-proparathyroid hormone leader sequence inhibits cell-free processing of placental, parathyroid, and pituitary prehormones. J Biol Chem. 1980 Dec 10; 255(23):11478-83. PMID: 7440551.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  131. Kronenberg HM, McDevitt BE, Majzoub JA, Nathans J, Sharp PA, Potts JT, Rich A. Cloning and nucleotide sequence of DNA coding for bovine preproparathyroid hormone. Proc Natl Acad Sci U S A. 1979 Oct; 76(10):4981-5. PMID: 388425.
    Citations: 23     Fields:    Translation:AnimalsCells
  132. Majzoub JA, Kronenberg HM, Potts JT, Rich A, Habener JF. Identification and cell-free translation of mRNA coding for a precursor of parathyroid secretory protein. J Biol Chem. 1979 Aug 10; 254(15):7449-55. PMID: 457691.
    Citations: 6     Fields:    Translation:AnimalsCells
  133. Graboys TB, Majzoub JA. Letter: "Smudge" ECG. N Engl J Med. 1975 Jan 02; 292(1):50. PMID: 1109197.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.