Harvard Catalyst Profiles

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Arjun Ramesh Khanna, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Musaeus CS, Engedal K, Høgh P, Jelic V, Khanna AR, Kjaer TW, Mørup M, Naik M, Oeksengaard AR, Santarnecchi E, Snaedal J, Wahlund LO, Waldemar G, Andersen BB. Changes in the left temporal microstate are a sign of cognitive decline in patients with Alzheimer's disease. Brain Behav. 2020 Jun; 10(6):e01630. PMID: 32338460.
    Citations:    
  2. Piantadosi A, Kanjilal S, Ganesh V, Khanna A, Hyle EP, Rosand J, Bold T, Metsky HC, Lemieux J, Leone MJ, Freimark L, Matranga CB, Adams G, McGrath G, Zamirpour S, Telford S, Rosenberg E, Cho T, Frosch MP, Goldberg MB, Mukerji SS, Sabeti PC. Rapid Detection of Powassan Virus in a Patient With Encephalitis by Metagenomic Sequencing. Clin Infect Dis. 2018 02 10; 66(5):789-792. PMID: 29020227.
    Citations: 1     Fields:    
  3. Santarnecchi E, Khanna AR, Musaeus CS, Benwell CSY, Davila P, Farzan F, Matham S, Pascual-Leone A, Shafi MM. EEG Microstate Correlates of Fluid Intelligence and Response to Cognitive Training. Brain Topogr. 2017 Jul; 30(4):502-520. PMID: 28493012.
    Citations: 2     Fields:    Translation:Humans
  4. Shekarabi M, Zhang J, Khanna AR, Ellison DH, Delpire E, Kahle KT. WNK Kinase Signaling in Ion Homeostasis and Human Disease. Cell Metab. 2017 02 07; 25(2):285-299. PMID: 28178566.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  5. Zhang J, Gao G, Begum G, Wang J, Khanna AR, Shmukler BE, Daubner GM, de Los Heros P, Davies P, Varghese J, Bhuiyan MI, Duan J, Zhang J, Duran D, Alper SL, Sun D, Elledge SJ, Alessi DR, Kahle KT. Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain. Sci Rep. 2016 10 26; 6:35986. PMID: 27782176.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  6. Khanna AR, Yanamadala V, Coumans JV. Effect of intraoperative navigation on operative time in 1-level lumbar fusion surgery. J Clin Neurosci. 2016 Oct; 32:72-6. PMID: 27364319.
    Citations:    Fields:    Translation:Humans
  7. Kahle KT, Khanna AR, Duan J, Staley KJ, Delpire E, Poduri A. The KCC2 Cotransporter and Human Epilepsy: Getting Excited About Inhibition. Neuroscientist. 2016 12; 22(6):555-562. PMID: 27130838.
    Citations: 9     Fields:    Translation:HumansAnimals
  8. Kahle KT, Schmouth JF, Lavastre V, Latremoliere A, Zhang J, Andrews N, Omura T, Laganière J, Rochefort D, Hince P, Castonguay G, Gaudet R, Mapplebeck JC, Sotocinal SG, Duan J, Ward C, Khanna AR, Mogil JS, Dion PA, Woolf CJ, Inquimbert P, Rouleau GA. Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition. Sci Signal. 2016 Mar 29; 9(421):ra32. PMID: 27025876.
    Citations: 4     Fields:    Translation:AnimalsCells
  9. Merner ND, Mercado A, Khanna AR, Hodgkinson A, Bruat V, Awadalla P, Gamba G, Rouleau GA, Kahle KT. Gain-of-function missense variant in SLC12A2, encoding the bumetanide-sensitive NKCC1 cotransporter, identified in human schizophrenia. J Psychiatr Res. 2016 Jun; 77:22-6. PMID: 26955005.
    Citations: 5     Fields:    Translation:AnimalsCells
  10. Khanna AR, Coumans JV. Spontaneous Improvement of Chiari I Malformation and Syringomyelia in a Patient With Cystic Fibrosis: Case Report. Neurosurgery. 2016 Feb; 78(2):E305-8. PMID: 26308731.
    Citations: 1     Fields:    Translation:Humans
  11. Merner ND, Chandler MR, Bourassa C, Liang B, Khanna AR, Dion P, Rouleau GA, Kahle KT. Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia. Front Cell Neurosci. 2015; 9:386. PMID: 26528127.
    Citations: 11     
  12. Adragna NC, Ravilla NB, Lauf PK, Begum G, Khanna AR, Sun D, Kahle KT. Regulated phosphorylation of the K-Cl cotransporter KCC3 is a molecular switch of intracellular potassium content and cell volume homeostasis. Front Cell Neurosci. 2015; 9:255. PMID: 26217182.
    Citations: 4     
  13. Kahle KT, Khanna AR, Alper SL, Adragna NC, Lauf PK, Sun D, Delpire E. K-Cl cotransporters, cell volume homeostasis, and neurological disease. Trends Mol Med. 2015 Aug; 21(8):513-23. PMID: 26142773.
    Citations: 14     Fields:    Translation:HumansCells
  14. Friedel P, Kahle KT, Zhang J, Hertz N, Pisella LI, Buhler E, Schaller F, Duan J, Khanna AR, Bishop PN, Shokat KM, Medina I. WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons. Sci Signal. 2015 Jun 30; 8(383):ra65. PMID: 26126716.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  15. Khanna A, Pascual-Leone A, Michel CM, Farzan F. Microstates in resting-state EEG: current status and future directions. Neurosci Biobehav Rev. 2015 Feb; 49:105-13. PMID: 25526823.
    Citations: 24     Fields:    Translation:Humans
  16. Walcott BP, Khanna A, Yanamadala V, Coumans JV, Peterfreund RA. Cost analysis of spinal and general anesthesia for the surgical treatment of lumbar spondylosis. J Clin Neurosci. 2015 Mar; 22(3):539-43. PMID: 25510535.
    Citations:    Fields:    Translation:Humans
  17. Khanna A, Pascual-Leone A, Farzan F. Reliability of resting-state microstate features in electroencephalography. PLoS One. 2014; 9(12):e114163. PMID: 25479614.
    Citations: 7     Fields:    Translation:Humans
  18. Walcott BP, Khanna A, Kwon CS, Phillips HW, Nahed BV, Coumans JV. Time interval to surgery and outcomes following the surgical treatment of acute traumatic subdural hematoma. J Clin Neurosci. 2014 Dec; 21(12):2107-11. PMID: 25065950.
    Citations: 4     Fields:    Translation:Humans
  19. Kahle KT, Merner ND, Friedel P, Silayeva L, Liang B, Khanna A, Shang Y, Lachance-Touchette P, Bourassa C, Levert A, Dion PA, Walcott B, Spiegelman D, Dionne-Laporte A, Hodgkinson A, Awadalla P, Nikbakht H, Majewski J, Cossette P, Deeb TZ, Moss SJ, Medina I, Rouleau GA. Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy. EMBO Rep. 2014 Jul; 15(7):766-74. PMID: 24928908.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  20. Kahle KT, Khanna A, Clapham DE, Woolf CJ. Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain. JAMA Neurol. 2014 May; 71(5):640-5. PMID: 24615367.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  21. Khanna A, Walcott BP, Kahle KT, Simard JM. Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans. Neurosurg Focus. 2014 Jan; 36(1):E11. PMID: 24380477.
    Citations: 5     Fields:    Translation:Humans
  22. Khanna A, Kahle KT, Walcott BP, Gerzanich V, Simard JM. Disruption of ion homeostasis in the neurogliovascular unit underlies the pathogenesis of ischemic cerebral edema. Transl Stroke Res. 2014 Feb; 5(1):3-16. PMID: 24323726.
    Citations: 22     Fields:    Translation:HumansCells
  23. Khanna A, Venteicher AS, Walcott BP, Kahle KT, Mordes DA, William CM, Ghogawala Z, Ogilvy CS. Glioblastoma mimicking an arteriovenous malformation. Front Neurol. 2013; 4:144. PMID: 24137154.
    Citations: 2     
  24. Strong C, Yanamadala V, Khanna A, Walcott BP, Nahed BV, Borges LF, Coumans JV. Surgical treatment options and management strategies of metastatic renal cell carcinoma to the lumbar spinal nerve roots. J Clin Neurosci. 2013 Nov; 20(11):1546-9. PMID: 23931936.
    Citations: 6     Fields:    Translation:Humans
  25. Khanna A, Walcott BP, Kahle KT. Limitations of Current GABA Agonists in Neonatal Seizures: Toward GABA Modulation Via the Targeting of Neuronal Cl(-) Transport. Front Neurol. 2013; 4:78. PMID: 23805124.
    Citations: 9     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.