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Mehdi Najafzadeh, Ph.D.

Title
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Department
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Biography
2007 - 2008
Graduate Entrance Scholarship
2009 - 2011
Frederick Banting and Charles Best Canada Graduate Scholarship
2009 - 2011
Four-Year Fellowship, University of British Columbia
2012 - 2014
CIHR Postdoctoral Fellowship

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG060163 (Mehdi Najafzadeh) Aug 1, 2018 - Jul 30, 2023
    NIH/NIA
    Generalizing data from randomized trials to predict long-term treatment outcomes in older populations
    Role: PI

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Darrow JJ, Najafzadeh M, Stefanini K, Kesselheim AS. Regulatory approval characteristics of antimicrobial versus non-antimicrobial products, 1984-2018: an evaluation of Food and Drug Administration flexibilities. Lancet Infect Dis. 2020 Jul; 20(7):e159-e164. PMID: 32502431.
    Citations:    
  2. Greenzang KA, Al-Sayegh H, Ma C, Najafzadeh M, Wittenberg E, Mack JW. Parental Considerations Regarding Cure and Late Effects for Children With Cancer. Pediatrics. 2020 05; 145(5). PMID: 32284427.
    Citations:    
  3. D'Andrea E, Ahnen DJ, Sussman DA, Najafzadeh M. Quantifying the impact of adherence to screening strategies on colorectal cancer incidence and mortality. Cancer Med. 2020 01; 9(2):824-836. PMID: 31777197.
    Citations:    
  4. Patorno E, Najafzadeh M, Pawar A, Franklin JM, Déruaz-Luyet A, Brodovicz KG, Santiago Ortiz AJ, Bessette LG, Kulldorff M, Schneeweiss S. The EMPagliflozin compaRative effectIveness and SafEty (EMPRISE) study programme: Design and exposure accrual for an evaluation of empagliflozin in routine clinical care. Endocrinol Diabetes Metab. 2020 Jan; 3(1):e00103. PMID: 31922030.
    Citations:    
  5. Silva IR, Gagne JJ, Najafzadeh M, Kulldorff M. Exact sequential analysis for multiple weighted binomial end points. Stat Med. 2020 02 10; 39(3):340-351. PMID: 31769079.
    Citations:    
  6. Sarpatwari A, DiBello J, Zakarian M, Najafzadeh M, Kesselheim AS. Competition and price among brand-name drugs in the same class: A systematic review of the evidence. PLoS Med. 2019 07; 16(7):e1002872. PMID: 31361747.
    Citations:    
  7. Li DG, Najafzadeh M, Kesselheim AS, Mostaghimi A. Spending on World Health Organization essential medicines in Medicare Part D, 2011-15: retrospective cost analysis. BMJ. 2019 07 17; 366:l4257. PMID: 31315833.
    Citations:    
  8. D'Andrea E, Choudhry NK, Raby B, Weinhouse GL, Najafzadeh M. A bronchial-airway gene-expression classifier to improve the diagnosis of lung cancer: Clinical outcomes and cost-effectiveness analysis. Int J Cancer. 2020 02 01; 146(3):781-790. PMID: 30977121.
    Citations:    
  9. Donnan JR, Johnston K, Chibrikov E, Marra CA, Aubrey-Bassler K, Najafzadeh M, Nguyen H, Gamble JM. Capturing Adult Patient Preferences Toward Benefits and Risks of Second-Line Antihyperglycemic Medications Used in Type 2 Diabetes: A Discrete Choice Experiment. Can J Diabetes. 2020 Feb; 44(1):6-13. PMID: 31311729.
    Citations:    
  10. Patorno E, Pawar A, Franklin JM, Najafzadeh M, Déruaz-Luyet A, Brodovicz KG, Sambevski S, Bessette LG, Santiago Ortiz AJ, Kulldorff M, Schneeweiss S. Empagliflozin and the Risk of Heart Failure Hospitalization in Routine Clinical Care. Circulation. 2019 06 18; 139(25):2822-2830. PMID: 30955357.
    Citations:    
  11. Najafzadeh M, Schneeweiss S, Choudhry NK, Avorn J, Gagne JJ. General Population vs. Patient Preferences in Anticoagulant Therapy: A Discrete Choice Experiment. Patient. 2019 04; 12(2):235-246. PMID: 30242575.
    Citations:    Fields:    
  12. Sinha MS, Najafzadeh M, Rajasingh EK, Love J, Kesselheim AS. Labeling Changes and Costs for Clinical Trials Performed Under the US Food and Drug Administration Pediatric Exclusivity Extension, 2007 to 2012. JAMA Intern Med. 2018 11 01; 178(11):1458-1466. PMID: 30264138.
    Citations:    
  13. Wang SV, Schneeweiss S, Gagne JJ, Evers T, Gerlinger C, Desai R, Najafzadeh M. Using Real-World Data to Extrapolate Evidence From Randomized Controlled Trials. Clin Pharmacol Ther. 2019 05; 105(5):1156-1163. PMID: 30107034.
    Citations:    Fields:    
  14. Gagne JJ, Tsacogianis T, Bruce Wirta S, Rogers JR, Calado F, Chang CL, Turner SJ, Schlienger RG, Balas B, Abdurrob A, Najafzadeh M, Wang SV. Characteristics of early sacubitril/valsartan patients and considerations for studies in electronic health record data. J Comp Eff Res. 2018 11; 7(11):1073-1082. PMID: 30156128.
    Citations:    Fields:    
  15. Najafzadeh M, Schneeweiss S, Choudhry NK, Wang SV, Gagne JJ. Simulation for Predicting Effectiveness and Safety of New Cardiovascular Drugs in Routine Care Populations. Clin Pharmacol Ther. 2018 11; 104(5):1008-1015. PMID: 29424437.
    Citations:    Fields:    
  16. Najafzadeh M. Evolution of Herpes Zoster Vaccines and Their Economic Value. JAMA Intern Med. 2018 02 01; 178(2):258-259. PMID: 29297047.
    Citations:    Fields:    
  17. Najafzadeh M, Garces JA, Maciel A. Economic Evaluation of Implementing a Novel Pharmacogenomic Test (IDgenetix®) to Guide Treatment of Patients with Depression and/or Anxiety. Pharmacoeconomics. 2017 Dec; 35(12):1297-1310. PMID: 29110140.
    Citations: 1     Fields:    Translation:Humans
  18. Najafzadeh M, Gagne JJ, Schneeweiss S. Synergies From Integrating Randomized Controlled Trials and Real-World Data Analyses. Clin Pharmacol Ther. 2017 Dec; 102(6):914-916. PMID: 29034448.
    Citations:    Fields:    Translation:Humans
  19. McWilliams JM, Najafzadeh M, Shrank WH, Polinski JM. Association of Changes in Medication Use and Adherence With Accountable Care Organization Exposure in Patients With Cardiovascular Disease or Diabetes. JAMA Cardiol. 2017 09 01; 2(9):1019-1023. PMID: 28700790.
    Citations: 1     Fields:    
  20. Mamiya H, Tahara RK, Tolaney SM, Choudhry NK, Najafzadeh M. Cost-effectiveness of palbociclib in hormone receptor-positive advanced breast cancer. Ann Oncol. 2017 Aug 01; 28(8):1825-1831. PMID: 28472324.
    Citations:    Fields:    Translation:Humans
  21. Huybrechts KF, Desai RJ, Park M, Gagne JJ, Najafzadeh M, Avorn J. The Potential Return on Public Investment in Detecting Adverse Drug Effects. Med Care. 2017 06; 55(6):545-551. PMID: 28505041.
    Citations:    Fields:    
  22. Najafzadeh M, Schneeweiss S. From Trial to Target Populations - Calibrating Real-World Data. N Engl J Med. 2017 Mar 30; 376(13):1203-1205. PMID: 28355503.
    Citations: 3     Fields:    Translation:Humans
  23. Marra F, Chong M, Najafzadeh M. Increasing incidence associated with herpes zoster infection in British Columbia, Canada. BMC Infect Dis. 2016 Oct 20; 16(1):589. PMID: 27765026.
    Citations: 5     Fields:    
  24. Najafzadeh M, Schnipper JL, Shrank WH, Kymes S, Brennan TA, Choudhry NK . Economic Value of Pharmacist-Led Medication Reconciliation for Reducing Medication Errors After Hospital Discharge. American Journal of Managed Care. 2016; 10(22):654-61. View Publication.
  25. Najafzadeh M, Schnipper JL, Shrank WH, Kymes S, Brennan TA, Choudhry NK. Economic value of pharmacist-led medication reconciliation for reducing medication errors after hospital discharge. Am J Manag Care. 2016 Oct; 22(10):654-661. PMID: 28557517.
    Citations:    Fields:    Translation:Humans
  26. Mott DJ, Najafzadeh M. Whose preferences should be elicited for use in health-care decision-making? A case study using anticoagulant therapy. Expert Rev Pharmacoecon Outcomes Res. 2016; 16(1):33-9. PMID: 26560704.
    Citations: 2     Fields:    Translation:Humans
  27. Ungar WJ, Hadioonzadeh A, Najafzadeh M, Tsao NW, Dell S, Lynd LD. Parents and adolescents preferences for asthma control: a best-worst scaling choice experiment using an orthogonal main effects design. BMC Pulm Med. 2015 Nov 17; 15:146. PMID: 26577906.
    Citations: 1     Fields:    Translation:Humans
  28. Gagne JJ, Najafzadeh M, Choudhry NK, Bykov K, Kahler KH, Martin D, Rogers JR, Schneeweiss S. Comparison of Benefit-Risk Assessment Methods for Prospective Monitoring of Newly Marketed Drugs: A Simulation Study. Value Health. 2015 Dec; 18(8):1057-62. PMID: 26686791.
    Citations:    Fields:    Translation:Humans
  29. Najafzadeh M, Kim SC, Patterson C, Schneeweiss S, Katz JN, Brick GW, Ready JE, Polinski JM, Patorno E. Patients' perception about risks and benefits of antithrombotic treatment for the prevention of venous thromboembolism (VTE) after orthopedic surgery: a qualitative study. BMC Musculoskelet Disord. 2015 Oct 26; 16:319. PMID: 26503220.
    Citations: 1     Fields:    Translation:Humans
  30. Gagne JJ, Bykov K, Najafzadeh M, Choudhry NK, Martin DP, Kahler KH, Rogers JR, Schneeweiss S. Prospective Benefit-Risk Monitoring of New Drugs for Rapid Assessment of Net Favorability in Electronic Health Care Data. Value Health. 2015 Dec; 18(8):1063-9. PMID: 26686792.
    Citations: 1     Fields:    Translation:Humans
  31. Najafzadeh M, Andersson K, Shrank WH, Krumme AA, Matlin OS, Brennan T, Avorn J, Choudhry NK. Cost-effectiveness of novel regimens for the treatment of hepatitis C virus. Ann Intern Med. 2015 Mar 17; 162(6):407-19. PMID: 25775313.
    Citations: 56     Fields:    Translation:HumansCells
  32. Najafzadeh M, Schneeweiss S, Choudhry N, Bykov K, Kahler KH, Martin DP, Gagne JJ. A unified framework for classification of methods for benefit-risk assessment. Value Health. 2015 Mar; 18(2):250-9. PMID: 25773560.
    Citations: 1     Fields:    Translation:Humans
  33. Najafzadeh M, Gagne JJ, Choudhry NK, Polinski JM, Avorn J, Schneeweiss SS. Patients' preferences in anticoagulant therapy: discrete choice experiment. Circ Cardiovasc Qual Outcomes. 2014 Nov; 7(6):912-9. PMID: 25387782.
    Citations: 3     Fields:    Translation:Humans
  34. Ungar WJ, Hadioonzadeh A, Najafzadeh M, Tsao NW, Dell S, Lynd LD. Quantifying preferences for asthma control in parents and adolescents using best-worst scaling. Respir Med. 2014 Jun; 108(6):842-51. PMID: 24780719.
    Citations: 5     Fields:    Translation:Humans
  35. Shields AE, Najafzadeh M, Schachter AB. Bumps along the translational pathway: anticipating uptake of tailored smoking cessation treatment. Per Med. 2013 11 01; 10(8):813-825. PMID: 24409196.
    Citations: 2     
  36. Najafzadeh M, Johnston KM, Peacock SJ, Connors JM, Marra MA, Lynd LD, Marra CA. Genomic testing to determine drug response: measuring preferences of the public and patients using Discrete Choice Experiment (DCE). BMC Health Serv Res. 2013 Oct 31; 13:454. PMID: 24176050.
    Citations: 4     Fields:    Translation:Humans
  37. Najafzadeh M, Marra CA, Lynd L, Wiseman S. Authors' response to "comparative effectiveness and personalized medicine" by Dr. J.C. Hornberger. Value Health. 2013 Jun; 16(4):697. PMID: 23796305.
    Citations:    
  38. Najafzadeh M, Davis JC, Joshi P, Marra C. Barriers for integrating personalized medicine into clinical practice: a qualitative analysis. Am J Med Genet A. 2013 Apr; 161A(4):758-63. PMID: 23444119.
    Citations: 4     Fields:    Translation:Humans
  39. Sadatsafavi M, Bansback N, Zafari Z, Najafzadeh M, Marra C. Need for speed: an efficient algorithm for calculation of single-parameter expected value of partial perfect information. Value Health. 2013 Mar-Apr; 16(2):438-48. PMID: 23538197.
    Citations: 8     Fields:    Translation:Humans
  40. Najafzadeh M, Marra CA, Lynd LD, Sadatsafavi M, FitzGerald JM, McManus B, Sin D. Future impact of various interventions on the burden of COPD in Canada: a dynamic population model. PLoS One. 2012; 7(10):e46746. PMID: 23071626.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  41. Najafzadeh M, Marra CA, Lynd LD, Wiseman SM. Cost-effectiveness of using a molecular diagnostic test to improve preoperative diagnosis of thyroid cancer. Value Health. 2012 Dec; 15(8):1005-13. PMID: 23244801.
    Citations: 5     Fields:    Translation:Humans
  42. Najafzadeh M, Lynd LD, Davis JC, Bryan S, Anis A, Marra M, Marra CA. Barriers to integrating personalized medicine into clinical practice: a best-worst scaling choice experiment. Genet Med. 2012 May; 14(5):520-6. PMID: 22241089.
    Citations: 12     Fields:    Translation:Humans
  43. Davis JC, Marra CA, Robertson MC, Najafzadeh M, Liu-Ambrose T. Sustained economic benefits of resistance training in community-dwelling senior women. J Am Geriatr Soc. 2011 Jul; 59(7):1232-7. PMID: 21718265.
    Citations: 2     Fields:    Translation:Humans
  44. Davis JC, Marra CA, Beattie BL, Robertson MC, Najafzadeh M, Graf P, Nagamatsu LS, Liu-Ambrose T. Sustained cognitive and economic benefits of resistance training among community-dwelling senior women: a 1-year follow-up study of the Brain Power study. Arch Intern Med. 2010 Dec 13; 170(22):2036-8. PMID: 21149764.
    Citations: 8     Fields:    Translation:Humans
  45. Lester RT, Ritvo P, Mills EJ, Kariri A, Karanja S, Chung MH, Jack W, Habyarimana J, Sadatsafavi M, Najafzadeh M, Marra CA, Estambale B, Ngugi E, Ball TB, Thabane L, Gelmon LJ, Kimani J, Ackers M, Plummer FA. Effects of a mobile phone short message service on antiretroviral treatment adherence in Kenya (WelTel Kenya1): a randomised trial. Lancet. 2010 Nov 27; 376(9755):1838-45. PMID: 21071074.
    Citations: 386     Fields:    Translation:HumansCells
  46. Lynd LD, Marra CA, Najafzadeh M, Sadatsafavi M. A quantitative evaluation of the regulatory assessment of the benefits and risks of rofecoxib relative to naproxen: an application of the incremental net-benefit framework. Pharmacoepidemiol Drug Saf. 2010 Nov; 19(11):1172-80. PMID: 20602338.
    Citations: 2     Fields:    Translation:Humans
  47. Davis JC, Marra CA, Robertson MC, Khan KM, Najafzadeh M, Ashe MC, Liu-Ambrose T. Economic evaluation of dose-response resistance training in older women: a cost-effectiveness and cost-utility analysis. Osteoporos Int. 2011 May; 22(5):1355-66. PMID: 20683707.
    Citations: 11     Fields:    Translation:Humans
  48. Johnston KM, Marra CA, Connors JM, Najafzadeh M, Sehn L, Peacock SJ. Cost-effectiveness of the addition of rituximab to CHOP chemotherapy in first-line treatment for diffuse large B-cell lymphoma in a population-based observational cohort in British Columbia, Canada. Value Health. 2010 Sep-Oct; 13(6):703-11. PMID: 20561333.
    Citations: 7     Fields:    Translation:Humans
  49. Davis JC, Marra CA, Najafzadeh M, Liu-Ambrose T. The independent contribution of executive functions to health related quality of life in older women. BMC Geriatr. 2010 Apr 01; 10:16. PMID: 20359355.
    Citations: 14     Fields:    Translation:Humans
  50. Lynd LD, Najafzadeh M, Colley L, Byrne MF, Willan AR, Sculpher MJ, Johnson FR, Hauber AB. Using the incremental net benefit framework for quantitative benefit-risk analysis in regulatory decision-making--a case study of alosetron in irritable bowel syndrome. Value Health. 2010 Jun-Jul; 13(4):411-7. PMID: 19744297.
    Citations: 4     Fields:    Translation:Humans
  51. Najafzadeh M, Marra CA, Galanis E, Patrick DM. Cost effectiveness of herpes zoster vaccine in Canada. Pharmacoeconomics. 2009; 27(12):991-1004. PMID: 19908924.
    Citations: 14     Fields:    Translation:Humans
  52. Najafzadeh M, Marra CA, Sadatsafavi M, Aaron SD, Sullivan SD, Vandemheen KL, Jones PW, Fitzgerald JM. Cost effectiveness of therapy with combinations of long acting bronchodilators and inhaled steroids for treatment of COPD. Thorax. 2008 Nov; 63(11):962-7. PMID: 18621985.
    Citations: 17     Fields:    Translation:Humans
  53. Najafzadeh M, Sadatsafavi M, Marra CA. Interpretation of results of the cost-effectiveness analysis reported by Pellissier et al. on October 2007. Vaccine. 2008 Sep 26; 26(41):5244; author reply 5245. PMID: 18619510.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  54. Sadatsafavi M, Najafzadeh M, Lynd L, Marra C. Reliability studies of diagnostic tests are not using enough observers for robust estimation of interobserver agreement: a simulation study. J Clin Epidemiol. 2008 Jul; 61(7):722-7. PMID: 18486446.
    Citations: 7     Fields:    Translation:Humans
  55. Sadatsafavi M, Najafzadeh M, Marra C. Technical note: acceptability curves could be misleading when correlated strategies are compared. Med Decis Making. 2008 May-Jun; 28(3):306-7. PMID: 18270304.
    Citations: 2     Fields:    Translation:Humans
  56. Marra CA, Marion SA, Guh DP, Najafzadeh M, Wolfe F, Esdaile JM, Clarke AE, Gignac MA, Anis AH. Not all "quality-adjusted life years" are equal. J Clin Epidemiol. 2007 Jun; 60(6):616-24. PMID: 17493521.
    Citations: 25     Fields:    Translation:Humans
  57. Sadatsafavi M, Najafzadeh M. Cost-optimisation of screening for latent tuberculosis in close contacts. Eur Respir J. 2006 Dec; 28(6):1285; author reply 1285-6. PMID: 17138688.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.