Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Craig Todd Basson, M.D.,Ph.D., M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. RC1HL100579 (HATCHER, CATHY J) Sep 30, 2009 - Aug 31, 2012
    Let-7 miRNA control of heart development
    Role: Co-Principal Investigator
  2. R01HL080663 (BASSON, CRAIG T) Apr 1, 2005 - Mar 31, 2010
    TBX5 and Coronary Blood Vessel Development
    Role: Principal Investigator
  3. R01HL066214 (BASSON, CRAIG T) Jul 1, 2001 - Jun 30, 2007
    Role: Principal Investigator
  4. R01HL061785 (HATCHER, CATHY J) Jul 1, 1999 - Jun 30, 2013
    Molecular Genetics of Carney Complex
    Role: Co-Principal Investigator
  5. K08HL003468 (BASSON, CRAIG T) Jul 1, 1996 - Jun 30, 2001
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Rader DJ, Maratos-Flier E, Nguyen A, Hom D, Ferriere M, Li Y, Kompa J, Martic M, Hinder M, Basson CT, Yowe D, Diener J, Goldfine AB. LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in obese adults with modest hypertriglyceridemia. J Clin Endocrinol Metab. 2021 Aug 25. PMID: 34431493.
    Citations:    Fields:    
  2. Tan S, Ignatenko S, Wagner F, Dokras A, Seufert J, Zwanziger D, Dunschen K, Zakaria M, Huseinovic N, Basson CT, Mahling P, Fuhrer D, Hinder M. Licogliflozin versus placebo in women with polycystic ovary syndrome: A randomized, double-blind, phase 2 trial. Diabetes Obes Metab. 2021 Nov; 23(11):2595-2599. PMID: 34263971.
    Citations:    Fields:    
  3. Kahaly GJ, Stan MN, Frommer L, Gergely P, Colin L, Amer A, Schuhmann I, Espie P, Rush JS, Basson C, He Y. A Novel Anti-CD40 Monoclonal Antibody, Iscalimab, for Control of Graves Hyperthyroidism-A Proof-of-Concept Trial. J Clin Endocrinol Metab. 2020 03 01; 105(3). PMID: 31512728.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  4. Kahaly GJ, Stan MN, Frommer L, Gergely P, Colin L, Amer A, Schuhmann I, Espie P, Rush JS, Basson C, He YL. A Novel Anti-Cd40 Monoclonal Antibody, Iscalimab, for Control of Graves' Hyperthyroidism - A Proof-Of-Concept Trial. J Clin Endocrinol Metab. 2019 Sep 12. PMID: 31511866.
  5. Kahaly GJ, Stan MN, Frommer L, Gergely P, Colin L, Amer A, Schuhmann I, Espie P, Rush JS, Basson C, He YL. A Novel Anti-Cd40 Monoclonal Antibody, Iscalimab, for Control of Graves' Hyperthyroidism - A Proof-Of-Concept Trial. J Clin Endocrinol Metab. 2019 Sep 12. PMID: 31511865.
  6. Russell KS, Yates DP, Kramer CM, Feller A, Mahling P, Colin L, Clough T, Wang T, LaPerna L, Patel A, Lawall H, Shennak MM, Fulmer J, Nikol S, Smith WB, Müller OJ, Ratchford EV, Basson CT. A randomized, placebo-controlled trial of canakinumab in patients with peripheral artery disease. Vasc Med. 2019 10; 24(5):414-421. PMID: 31277561.
    Citations: 3     Fields:    Translation:Humans
  7. Koch AW, Schiering N, Melkko S, Ewert S, Salter J, Zhang Y, McCormack P, Yu J, Huang X, Chiu YH, Chen Z, Schleeger S, Horny G, DiPetrillo K, Muller L, Hein A, Villard F, Scharenberg M, Ramage P, Hassiepen U, Côté S, DeGagne J, Krantz C, Eder J, Stoll B, Kulmatycki K, Feldman DL, Hoffmann P, Basson CT, Frost RJA, Khder Y. MAA868, a novel FXI antibody with a unique binding mode, shows durable effects on markers of anticoagulation in humans. Blood. 2019 03 28; 133(13):1507-1516. PMID: 30692123.
    Citations: 9     Fields:    Translation:HumansAnimals
  8. Choudhury RP, Birks JS, Mani V, Biasiolli L, Robson MD, L'Allier PL, Gingras MA, Alie N, McLaughlin MA, Basson CT, Schecter AD, Svensson EC, Zhang Y, Yates D, Tardif JC, Fayad ZA. Arterial Effects of Canakinumab in Patients With Atherosclerosis and Type 2 Diabetes or Glucose Intolerance. J Am Coll Cardiol. 2016 10 18; 68(16):1769-1780. PMID: 27737744.
    Citations: 20     Fields:    Translation:HumansCTClinical Trials
  9. Weinsaft JW, Devereux RB, Preiss LR, Feher A, Roman MJ, Basson CT, Geevarghese A, Ravekes W, Dietz HC, Holmes K, Habashi J, Pyeritz RE, Bavaria J, Milewski K, LeMaire SA, Morris S, Milewicz DM, Prakash S, Maslen C, Song HK, Silberbach GM, Shohet RV, McDonnell N, Hendershot T, Eagle KA, Asch FM. Aortic Dissection in Patients With Genetically Mediated Aneurysms: Incidence and Predictors in the GenTAC Registry. J Am Coll Cardiol. 2016 06 14; 67(23):2744-2754. PMID: 27282895.
    Citations: 17     Fields:    Translation:Humans
  10. Diman NY, Brooks G, Kruithof BP, Elemento O, Seidman JG, Seidman CE, Basson CT, Hatcher CJ. Tbx5 is required for avian and Mammalian epicardial formation and coronary vasculogenesis. Circ Res. 2014 Oct 24; 115(10):834-44. PMID: 25245104.
    Citations: 13     Fields:    Translation:Animals
  11. Ganesh SK, Arnett DK, Assimes TL, Assimes TL, Basson CT, Chakravarti A, Ellinor PT, Engler MB, Goldmuntz E, Herrington DM, Hershberger RE, Hong Y, Johnson JA, Kittner SJ, McDermott DA, Meschia JF, Mestroni L, O'Donnell CJ, Psaty BM, Vasan RS, Ruel M, Shen WK, Terzic A, Waldman SA. Genetics and genomics for the prevention and treatment of cardiovascular disease: update: a scientific statement from the American Heart Association. Circulation. 2013 Dec 24; 128(25):2813-51. PMID: 24297835.
    Citations: 34     Fields:    Translation:Humans
  12. Cheng CH, Leferovich J, Zhang XM, Bedelbaeva K, Gourevitch D, Hatcher CJ, Basson CT, Heber-Katz E, Marx KA. Keratin gene expression profiles after digit amputation in C57BL/6 vs. regenerative MRL mice imply an early regenerative keratinocyte activated-like state. Physiol Genomics. 2013 Jun 03; 45(11):409-21. PMID: 23512742.
    Citations: 10     Fields:    Translation:AnimalsCells
  13. Bee KJ, Wilkes DC, Devereux RB, Basson CT, Hatcher CJ. TGFßRIIb mutations trigger aortic aneurysm pathogenesis by altering transforming growth factor ß2 signal transduction. Circ Cardiovasc Genet. 2012 Dec; 5(6):621-9. PMID: 23099432.
    Citations: 11     Fields:    Translation:HumansCells
  14. Kroner BL, Tolunay HE, Basson CT, Pyeritz RE, Holmes KW, Maslen CL, Milewicz DM, LeMaire SA, Hendershot T, Desvigne-Nickens P, Devereux RB, Dietz HC, Song HK, Ringer D, Mitchell M, Weinsaft JW, Ravekes W, Menashe V, Eagle KA. The National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions (GenTAC): results from phase I and scientific opportunities in phase II. Am Heart J. 2011 Oct; 162(4):627-632.e1. PMID: 21982653.
    Citations: 18     Fields:    Translation:Humans
  15. Mendoza DD, Kochar M, Devereux RB, Basson CT, Min JK, Holmes K, Dietz HC, Milewicz DM, LeMaire SA, Pyeritz RE, Bavaria JE, Maslen CL, Song H, Kroner BL, Eagle KA, Weinsaft JW. Impact of image analysis methodology on diagnostic and surgical classification of patients with thoracic aortic aneurysms. Ann Thorac Surg. 2011 Sep; 92(3):904-12. PMID: 21723533.
    Citations: 19     Fields:    Translation:Humans
  16. Kim L, Devereux RB, Basson CT. Impact of genetic insights into mendelian disease on cardiovascular clinical practice. Circulation. 2011 Feb 08; 123(5):544-50. PMID: 21300962.
    Citations: 3     Fields:    Translation:Humans
  17. Charitakis K, Basson CT. Can genetic testing improve our aim in hypertrophic cardiomyopathy? Circ Res. 2010 May 14; 106(9):1446-8. PMID: 20466986.
    Citations: 3     Fields:    Translation:Humans
  18. Wolf M, Basson CT. The molecular genetics of congenital heart disease: a review of recent developments. Curr Opin Cardiol. 2010 May; 25(3):192-7. PMID: 20186050.
    Citations: 23     Fields:    Translation:Humans
  19. Hatcher CJ, Basson CT. Specification of the cardiac conduction system by transcription factors. Circ Res. 2009 Sep 25; 105(7):620-30. PMID: 19797194.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  20. Song HK, Bavaria JE, Kindem MW, Holmes KW, Milewicz DM, Maslen CL, Pyeritz RE, Basson CT, Eagle K, Tolunay HE, Kroner BL, Dietz H, Menashe V, Devereux RB, Desvigne-Nickens P, Ravekes W, Weinsaft JW, Brambilla D, Stylianou MP, Hendershot T, Mitchell MS, LeMaire SA. Surgical treatment of patients enrolled in the national registry of genetically triggered thoracic aortic conditions. Ann Thorac Surg. 2009 Sep; 88(3):781-7; discussion 787-8. PMID: 19699898.
    Citations: 6     Fields:    Translation:Humans
  21. Kobayashi K, Luo M, Zhang Y, Wilkes DC, Ge G, Grieskamp T, Yamada C, Liu TC, Huang G, Basson CT, Kispert A, Greenspan DS, Sato TN. Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction. Nat Cell Biol. 2009 Jan; 11(1):46-55. PMID: 19079247.
    Citations: 100     Fields:    Translation:AnimalsCells
  22. McDermott DA, Hatcher CJ, Basson CT. Atrial Fibrillation and Other Clinical Manifestations of Altered TBX5 Dosage in Typical Holt-Oram Syndrome. Circ Res. 2008 Sep 26; 103(7):e96. PMID: 18818409.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  23. Lin AE, Basson CT, Goldmuntz E, Magoulas PL, McDermott DA, McDonald-McGinn DM, McPherson E, Morris CA, Noonan J, Nowak C, Pierpont ME, Pyeritz RE, Rope AF, Zackai E, Pober BR. Adults with genetic syndromes and cardiovascular abnormalities: clinical history and management. Genet Med. 2008 Jul; 10(7):469-94. PMID: 18580689.
    Citations: 22     Fields:    Translation:HumansCells
  24. Hatcher CJ, Basson CT. Disrupted intercalated discs. Is kindlin-2 required? Circ Res. 2008 Feb 29; 102(4):392-4. PMID: 18309105.
    Citations: 6     Fields:    Translation:AnimalsCells
  25. Gordon E, Panaghie G, Deng L, Bee KJ, Roepke TK, Krogh-Madsen T, Christini DJ, Ostrer H, Basson CT, Chung W, Abbott GW. A KCNE2 mutation in a patient with cardiac arrhythmia induced by auditory stimuli and serum electrolyte imbalance. Cardiovasc Res. 2008 Jan; 77(1):98-106. PMID: 18006462.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  26. Pierpont ME, Basson CT, Benson DW, Gelb BD, Giglia TM, Goldmuntz E, McGee G, Sable CA, Srivastava D, Webb CL. Genetic basis for congenital heart defects: current knowledge: a scientific statement from the American Heart Association Congenital Cardiac Defects Committee, Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. Circulation. 2007 Jun 12; 115(23):3015-38. PMID: 17519398.
    Citations: 277     Fields:    Translation:Humans
  27. Arnett DK, Baird AE, Barkley RA, Basson CT, Boerwinkle E, Ganesh SK, Herrington DM, Hong Y, Jaquish C, McDermott DA, O'Donnell CJ. Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group. Circulation. 2007 Jun 05; 115(22):2878-901. PMID: 17515457.
    Citations: 70     Fields:    Translation:Humans
  28. Mishra RK, Basson CT. Treatment goals for the management of lipids and inflammation for patients with coronary artery disease. Curr Treat Options Cardiovasc Med. 2007 Feb; 9(1):3-10. PMID: 17378971.
    Citations: 1     
  29. Charitakis K, Basson CT. Degenerating heart valves: fill them up with filamin? Circulation. 2007 Jan 02; 115(1):2-4. PMID: 17200451.
    Citations: 3     Fields:    Translation:HumansCells
  30. Bee KJ, Wilkes D, Devereux RB, Lerman BB, Dietz HC, Basson CT. Structural and functional genetic disorders of the great vessels and outflow tracts. Ann N Y Acad Sci. 2006 Nov; 1085:256-69. PMID: 17182942.
    Citations:    Fields:    Translation:HumansCells
  31. Heuser A, Plovie ER, Ellinor PT, Grossmann KS, Shin JT, Wichter T, Basson CT, Lerman BB, Sasse-Klaassen S, Thierfelder L, MacRae CA, Gerull B. Mutant desmocollin-2 causes arrhythmogenic right ventricular cardiomyopathy. Am J Hum Genet. 2006 Dec; 79(6):1081-8. PMID: 17186466.
    Citations: 76     Fields:    Translation:HumansAnimalsCells
  32. Burton KA, McDermott DA, Wilkes D, Poulsen MN, Nolan MA, Goldstein M, Basson CT, McKnight GS. Haploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and men. Mol Endocrinol. 2006 Oct; 20(10):2504-13. PMID: 16728532.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  33. Wilkes D, Charitakis K, Basson CT. Inherited disposition to cardiac myxoma development. Nat Rev Cancer. 2006 Feb; 6(2):157-65. PMID: 16491075.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  34. McDermott DA, Basson CT, Hatcher CJ. Genetics of cardiac septation defects and their pre-implantation diagnosis. Methods Mol Med. 2006; 126:19-42. PMID: 16930004.
    Citations: 2     Fields:    Translation:HumansCells
  35. Hatcher CJ, Basson CT. Taking a bite out of hypertrophic cardiomyopathy: soy diet and disease. J Clin Invest. 2006 Jan; 116(1):16-9. PMID: 16395397.
    Citations:    Fields:    Translation:HumansAnimals
  36. McDermott DA, Bressan MC, He J, Lee JS, Aftimos S, Brueckner M, Gilbert F, Graham GE, Hannibal MC, Innis JW, Pierpont ME, Raas-Rothschild A, Shanske AL, Smith WE, Spencer RH, St John-Sutton MG, van Maldergem L, Waggoner DJ, Weber M, Basson CT. TBX5 genetic testing validates strict clinical criteria for Holt-Oram syndrome. Pediatr Res. 2005 Nov; 58(5):981-6. PMID: 16183809.
    Citations: 48     Fields:    Translation:HumansCells
  37. McDermott DA, He J, Song YS, Kligman I, Basson CT. Update: PGD and Holt-Oram syndrome. . 2005 Jul 15; 136(2):223. PMID: 15940699.
    Citations: 2     Translation:Humans
  38. Bennett KR, Heath BJ, Creswell LL, Veugelers MA, McDermott DA, Barksdale S, Goldstein M, Basson CT. The carney complex: unusual skin findings and recurrent cardiac myxoma. Arch Dermatol. 2005 Jul; 141(7):916-8. PMID: 16027322.
    Citations: 1     Fields:    Translation:Humans
  39. Wilkes D, McDermott DA, Basson CT. Clinical phenotypes and molecular genetic mechanisms of Carney complex. Lancet Oncol. 2005 Jul; 6(7):501-8. PMID: 15992699.
    Citations: 17     Fields:    Translation:HumansAnimals
  40. Gerull B, Heuser A, Wichter T, Paul M, Basson CT, McDermott DA, Lerman BB, Markowitz SM, Ellinor PT, MacRae CA, Peters S, Grossmann KS, Drenckhahn J, Michely B, Sasse-Klaassen S, Birchmeier W, Dietz R, Breithardt G, Schulze-Bahr E, Thierfelder L. Mutations in the desmosomal protein plakophilin-2 are common in arrhythmogenic right ventricular cardiomyopathy. Nat Genet. 2004 Nov; 36(11):1162-4. PMID: 15489853.
    Citations: 214     Fields:    Translation:HumansCells
  41. Fraidenraich D, Stillwell E, Romero E, Wilkes D, Manova K, Basson CT, Benezra R. Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science. 2004 Oct 08; 306(5694):247-52. PMID: 15472070.
    Citations: 64     Fields:    Translation:AnimalsCells
  42. Veugelers M, Wilkes D, Burton K, McDermott DA, Song Y, Goldstein MM, La Perle K, Vaughan CJ, O'Hagan A, Bennett KR, Meyer BJ, Legius E, Karttunen M, Norio R, Kaariainen H, Lavyne M, Neau JP, Richter G, Kirali K, Farnsworth A, Stapleton K, Morelli P, Takanashi Y, Bamforth JS, Eitelberger F, Noszian I, Manfroi W, Powers J, Mochizuki Y, Imai T, Ko GT, Driscoll DA, Goldmuntz E, Edelberg JM, Collins A, Eccles D, Irvine AD, McKnight GS, Basson CT. Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14222-7. PMID: 15371594.
    Citations: 54     Fields:    Translation:HumansAnimalsCells
  43. Veugelers M, Bressan M, McDermott DA, Weremowicz S, Morton CC, Mabry CC, Lefaivre JF, Zunamon A, Destree A, Chaudron JM, Basson CT. Mutation of perinatal myosin heavy chain associated with a Carney complex variant. N Engl J Med. 2004 Jul 29; 351(5):460-9. PMID: 15282353.
    Citations: 39     Fields:    Translation:Humans
  44. Farr MA, Basson CT. Sparking the failing heart. N Engl J Med. 2004 Jul 08; 351(2):185-7. PMID: 15247360.
    Citations: 8     Fields:    Translation:HumansAnimals
  45. Hatcher CJ, Diman NY, Kim MS, Pennisi D, Song Y, Goldstein MM, Mikawa T, Basson CT. A role for Tbx5 in proepicardial cell migration during cardiogenesis. Physiol Genomics. 2004 Jul 08; 18(2):129-40. PMID: 15138308.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  46. He J, McDermott DA, Song Y, Gilbert F, Kligman I, Basson CT. Preimplantation genetic diagnosis of human congenital heart malformation and Holt-Oram syndrome. . 2004 Apr 01; 126A(1):93-8. PMID: 15039979.
    Citations: 5     Translation:HumansCells
  47. Zhou HM, Weskamp G, Chesneau V, Sahin U, Vortkamp A, Horiuchi K, Chiusaroli R, Hahn R, Wilkes D, Fisher P, Baron R, Manova K, Basson CT, Hempstead B, Blobel CP. Essential role for ADAM19 in cardiovascular morphogenesis. Mol Cell Biol. 2004 Jan; 24(1):96-104. PMID: 14673146.
    Citations: 35     Fields:    Translation:Animals
  48. Hatcher CJ, Diman NY, McDermott DA, Basson CT. Transcription factor cascades in congenital heart malformation. Trends Mol Med. 2003 Dec; 9(12):512-5. PMID: 14659463.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  49. Lerman BB, Basson CT. High-risk patients with ventricular preexcitation--a pendulum in motion. N Engl J Med. 2003 Nov 06; 349(19):1787-9. PMID: 14602876.
    Citations: 3     Fields:    Translation:Humans
  50. Collavoli A, Hatcher CJ, He J, Okin D, Deo R, Basson CT. TBX5 nuclear localization is mediated by dual cooperative intramolecular signals. J Mol Cell Cardiol. 2003 Oct; 35(10):1191-5. PMID: 14519429.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  51. Hatcher CJ, Basson CT. Modeling development of the epicardium and coronary vasculature: in vitro veritas? Circ Res. 2003 Mar 21; 92(5):477-9. PMID: 12649259.
    Citations: 1     Fields:    Translation:AnimalsCells
  52. Vaughan CJ, Hom Y, Okin DA, McDermott DA, Lerman BB, Basson CT. Molecular genetic analysis of PRKAG2 in sporadic Wolff-Parkinson-White syndrome. J Cardiovasc Electrophysiol. 2003 Mar; 14(3):263-8. PMID: 12716108.
    Citations: 4     Fields:    Translation:Humans
  53. Basson CT, Aretz HT. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 11-2002. A 27-year-old woman with two intracardiac masses and a history of endocrinopathy. N Engl J Med. 2002 Apr 11; 346(15):1152-8. PMID: 11948276.
    Citations: 9     Fields:    Translation:Humans
  54. Huang T, Lock JE, Marshall AC, Basson C, Seidman JG, Seidman CE. Causes of clinical diversity in human TBX5 mutations. Cold Spring Harb Symp Quant Biol. 2002; 67:115-20. PMID: 12858531.
    Citations: 2     Fields:    Translation:Humans
  55. Hatcher CJ, Basson CT. Getting the T-box dose right. Nat Med. 2001 Nov; 7(11):1185-6. PMID: 11689880.
    Citations: 7     Fields:    Translation:HumansAnimals
  56. Kim MS, Basson CT. Wrapping up DiGeorge syndrome in a T-box? Pediatr Res. 2001 Sep; 50(3):307-8. PMID: 11518813.
    Citations:    Fields:    Translation:HumansAnimals
  57. Vaughan CJ, Delanty N, Basson CT. Statin therapy and stroke prevention. Curr Opin Cardiol. 2001 Jul; 16(4):219-24. PMID: 11574782.
    Citations: 8     Fields:    Translation:Humans
  58. Basson CT. A molecular basis for Wolff-Parkinson-White syndrome. N Engl J Med. 2001 Jun 14; 344(24):1861-4. PMID: 11407351.
    Citations: 3     Fields:    Translation:HumansCells
  59. Vaughan CJ, Casey M, He J, Veugelers M, Henderson K, Guo D, Campagna R, Roman MJ, Milewicz DM, Devereux RB, Basson CT. Identification of a chromosome 11q23.2-q24 locus for familial aortic aneurysm disease, a genetically heterogeneous disorder. Circulation. 2001 May 22; 103(20):2469-75. PMID: 11369687.
    Citations: 33     Fields:    Translation:HumansCells
  60. Guo D, Hasham S, Kuang SQ, Vaughan CJ, Boerwinkle E, Chen H, Abuelo D, Dietz HC, Basson CT, Shete SS, Milewicz DM. Familial thoracic aortic aneurysms and dissections: genetic heterogeneity with a major locus mapping to 5q13-14. Circulation. 2001 May 22; 103(20):2461-8. PMID: 11369686.
    Citations: 45     Fields:    Translation:HumansCells
  61. Albertsen H, Thliveris A, Riley JH, Munroe DJ, Watkins P, Basson CT. Deriving probes from large-insert clones by PCR methods. Curr Protoc Hum Genet. 2001 May; Chapter 5:Unit 5.9. PMID: 18428296.
    Citations:    Fields:    Translation:HumansCells
  62. Vaughan CJ, Veugelers M, Basson CT. Tumors and the heart: molecular genetic advances. Curr Opin Cardiol. 2001 May; 16(3):195-200. PMID: 11357016.
    Citations: 4     Fields:    Translation:Humans
  63. Hatcher CJ, Kim MS, Mah CS, Goldstein MM, Wong B, Mikawa T, Basson CT. TBX5 transcription factor regulates cell proliferation during cardiogenesis. Dev Biol. 2001 Feb 15; 230(2):177-88. PMID: 11161571.
    Citations: 32     Fields:    Translation:HumansAnimalsCells
  64. Vaughan CJ, Delanty N, Basson CT. Do statins afford neuroprotection in patients with cerebral ischaemia and stroke? CNS Drugs. 2001; 15(8):589-96. PMID: 11524031.
    Citations: 6     Fields:    Translation:Humans
  65. Casey M, Vaughan CJ, He J, Hatcher CJ, Winter JM, Weremowicz S, Montgomery K, Kucherlapati R, Morton CC, Basson CT. Mutations in the protein kinase A R1alpha regulatory subunit cause familial cardiac myxomas and Carney complex. J Clin Invest. 2000 Sep; 106(5):R31-8. PMID: 10974026.
    Citations: 60     Fields:    Translation:HumansCells
  66. Hatcher CJ, Goldstein MM, Mah CS, Delia CS, Basson CT. Identification and localization of TBX5 transcription factor during human cardiac morphogenesis. Dev Dyn. 2000 Sep; 219(1):90-5. PMID: 10974675.
    Citations: 29     Fields:    Translation:HumansAnimals
  67. Vaughan CJ, Weremowicz S, Goldstein MM, Casey M, Hart M, Hahn RT, Devereux RB, Girardi L, Schoen FJ, Fletcher JA, Morton CC, Basson CT. A t(2;19)(p13;p13.2) in a giant invasive cardiac lipoma from a patient with multiple lipomatosis. Genes Chromosomes Cancer. 2000 Jun; 28(2):133-7. PMID: 10824997.
    Citations: 5     Fields:    Translation:HumansCells
  68. Basson CT. Holt-Oram syndrome vs heart-hand syndrome. Circulation. 2000 May 09; 101(18):E191. PMID: 10801768.
    Citations: 2     Fields:    Translation:HumansCells
  69. Hatcher CJ, Kim MS, Basson CT. Atrial form and function: lessons from human molecular genetics. Trends Cardiovasc Med. 2000 Apr; 10(3):93-101. PMID: 11428001.
    Citations: 2     Fields:    Translation:HumansAnimals
  70. Vaughan CJ, Gotto AM, Basson CT. The evolving role of statins in the management of atherosclerosis. J Am Coll Cardiol. 2000 Jan; 35(1):1-10. PMID: 10636252.
    Citations: 85     Fields:    Translation:Humans
  71. Vaughan CJ, Basson CT. Molecular determinants of atrial and ventricular septal defects and patent ductus arteriosus. Am J Med Genet. 2000; 97(4):304-9. PMID: 11376442.
    Citations: 16     Fields:    Translation:HumansAnimals
  72. Goldstein MM, Casey M, Carney JA, Basson CT. Molecular genetic diagnosis of the familial myxoma syndrome (Carney complex). Am J Med Genet. 1999 Sep 03; 86(1):62-5. PMID: 10440831.
    Citations: 5     Fields:    Translation:HumansCells
  73. Basson CT, Huang T, Lin RC, Bachinsky DR, Weremowicz S, Vaglio A, Bruzzone R, Quadrelli R, Lerone M, Romeo G, Silengo M, Pereira A, Krieger J, Mesquita SF, Kamisago M, Morton CC, Pierpont ME, Müller CW, Seidman JG, Seidman CE. Different TBX5 interactions in heart and limb defined by Holt-Oram syndrome mutations. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2919-24. PMID: 10077612.
    Citations: 92     Fields:    Translation:HumansCells
  74. Mah CS, Vaughan CJ, Basson CT. Advances in the molecular genetics of congenital structural heart disease. Genet Test. 1999; 3(2):157-72. PMID: 10464664.
    Citations: 2     Fields:    Translation:HumansAnimals
  75. Casey M, Mah C, Merliss AD, Kirschner LS, Taymans SE, Denio AE, Korf B, Irvine AD, Hughes A, Carney JA, Stratakis CA, Basson CT. Identification of a novel genetic locus for familial cardiac myxomas and Carney complex. Circulation. 1998 Dec 08; 98(23):2560-6. PMID: 9843463.
    Citations: 30     Fields:    Translation:HumansCells
  76. Stratakis CA, Kirschner LS, Taymans SE, Tomlinson IP, Marsh DJ, Torpy DJ, Giatzakis C, Eccles DM, Theaker J, Houlston RS, Blouin JL, Antonarakis SE, Basson CT, Eng C, Carney JA. Carney complex, Peutz-Jeghers syndrome, Cowden disease, and Bannayan-Zonana syndrome share cutaneous and endocrine manifestations, but not genetic loci. J Clin Endocrinol Metab. 1998 Aug; 83(8):2972-6. PMID: 9709978.
    Citations: 13     Fields:    Translation:Humans
  77. Schott JJ, Benson DW, Basson CT, Pease W, Silberbach GM, Moak JP, Maron BJ, Seidman CE, Seidman JG. Congenital heart disease caused by mutations in the transcription factor NKX2-5. Science. 1998 Jul 03; 281(5373):108-11. PMID: 9651244.
    Citations: 326     Fields:    Translation:HumansAnimalsCells
  78. Benson DW, Sharkey A, Fatkin D, Lang P, Basson CT, McDonough B, Strauss AW, Seidman JG, Seidman CE. Reduced penetrance, variable expressivity, and genetic heterogeneity of familial atrial septal defects. Circulation. 1998 May 26; 97(20):2043-8. PMID: 9610535.
    Citations: 22     Fields:    Translation:HumansCells
  79. Basson CT, MacRae CA, Korf B, Merliss A. Genetic heterogeneity of familial atrial myxoma syndromes (Carney complex). Am J Cardiol. 1997 Apr 01; 79(7):994-5. PMID: 9104925.
    Citations: 4     Fields:    Translation:HumansCells
  80. Basson CT, Bachinsky DR, Lin RC, Levi T, Elkins JA, Soults J, Grayzel D, Kroumpouzou E, Traill TA, Leblanc-Straceski J, Renault B, Kucherlapati R, Seidman JG, Seidman CE. Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome. Nat Genet. 1997 Jan; 15(1):30-5. PMID: 8988165.
    Citations: 273     Fields:    Translation:HumansAnimalsCells
  81. Benson DW, Basson CT, MacRae CA. New understandings in the genetics of congenital heart disease. Curr Opin Pediatr. 1996 Oct; 8(5):505-11. PMID: 8946132.
    Citations: 8     Fields:    Translation:Humans
  82. Basson CT, MacRae CA, Schoenberg-Fejzo M, Morton CC, Spinner NB, Genin A, Krug E, Seidman JG, Seidman CE. Identification, characterization, and chromosomal localization of the human homolog (hES) of ES/130. Genomics. 1996 Aug 01; 35(3):628-31. PMID: 8812507.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  83. MacRae CA, Ghaisas N, Kass S, Donnelly S, Basson CT, Watkins HC, Anan R, Thierfelder LH, McGarry K, Rowland E, et al. Familial Hypertrophic cardiomyopathy with Wolff-Parkinson-White syndrome maps to a locus on chromosome 7q3. J Clin Invest. 1995 Sep; 96(3):1216-20. PMID: 7657794.
    Citations: 26     Fields:    Translation:HumansCells
  84. Basson CT, Solomon SD, Weissman B, MacRae CA, Poznanski AK, Prieto F, Ruiz de la Fuente S, Pease WE, Levin SE, Holmes LB, et al. Genetic heterogeneity of heart-hand syndromes. Circulation. 1995 Mar 01; 91(5):1326-9. PMID: 7867169.
    Citations: 16     Fields:    Translation:HumansCells
  85. Kass S, MacRae C, Graber HL, Sparks EA, McNamara D, Boudoulas H, Basson CT, Baker PB, Cody RJ, Fishman MC, et al. A gene defect that causes conduction system disease and dilated cardiomyopathy maps to chromosome 1p1-1q1. Nat Genet. 1994 Aug; 7(4):546-51. PMID: 7951328.
    Citations: 24     Fields:    Translation:HumansCells
  86. Basson CT, Cowley GS, Solomon SD, Weissman B, Poznanski AK, Traill TA, Seidman JG, Seidman CE. The clinical and genetic spectrum of the Holt-Oram syndrome (heart-hand syndrome) N Engl J Med. 1994 Mar 31; 330(13):885-91. PMID: 8114858.
    Citations: 80     Fields:    Translation:HumansCells
  87. Johnson WC, Pagano TG, Basson CT, Madri JA, Gooley P, Armitage IM. Biologically active Arg-Gly-Asp oligopeptides assume a type II beta-turn in solution. Biochemistry. 1993 Jan 12; 32(1):268-73. PMID: 8418846.
    Citations: 9     Fields:    Translation:Cells
  88. Basson CT, Kocher O, Basson MD, Asis A, Madri JA. Differential modulation of vascular cell integrin and extracellular matrix expression in vitro by TGF-beta 1 correlates with reciprocal effects on cell migration. J Cell Physiol. 1992 Oct; 153(1):118-28. PMID: 1522126.
    Citations: 28     Fields:    Translation:AnimalsCells
  89. Madri JA, Bell L, Marx M, Merwin JR, Basson C, Prinz C. Effects of soluble factors and extracellular matrix components on vascular cell behavior in vitro and in vivo: models of de-endothelialization and repair. J Cell Biochem. 1991 Feb; 45(2):123-30. PMID: 1711525.
    Citations: 13     Fields:    Translation:AnimalsCells
  90. Basson CT, Knowles WJ, Bell L, Albelda SM, Castronovo V, Liotta LA, Madri JA. Spatiotemporal segregation of endothelial cell integrin and nonintegrin extracellular matrix-binding proteins during adhesion events. J Cell Biol. 1990 Mar; 110(3):789-801. PMID: 2407741.
    Citations: 27     Fields:    Translation:AnimalsCells
  91. Madri JA, Kocher O, Merwin JR, Bell L, Tucker A, Basson CT. Interactions of vascular cells with transforming growth factors-beta. Ann N Y Acad Sci. 1990; 593:243-58. PMID: 1695825.
    Citations: 5     Fields:    Translation:AnimalsCells
  92. Basson CT, Grace AM, Roberts R. Enzyme kinetics of a highly purified mitochondrial creatine kinase in comparison with cytosolic forms. Mol Cell Biochem. 1985 Jul; 67(2):151-9. PMID: 4047027.
    Citations: 5     Fields:    Translation:AnimalsCells
  93. Nicolson GL, Dulski K, Basson C, Welch DR. Preferential organ attachment and invasion in vitro by B16 melanoma cells selected for differing metastatic colonization and invasive properties. Invasion Metastasis. 1985; 5(3):144-58. PMID: 3997411.
    Citations: 20     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.