Harvard Catalyst Profiles

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Xiao-Feng Zheng, Ph.D.


Yale University, New Haven, CTPh.D05/2012Genetics
University of Maryland, College Park, MDB.S05/2005Chemistry and Biochemistry
2005 - 2006
National Cancer Institute Cancer Research Training Award
2015 - 2017
American Cancer Society Postdoctoral Fellowship
2021 - 2022
Friends of Dana-Farber Fund: Women's Cancer Research
2022 - 2022
Susan F. Smith Center for Women's Cancers Breast and Gynecologic Cancer Innovation Award

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li F, Kozono D, Deraska P, Branigan T, Dunn C, Zheng XF, Parmar K, Nguyen H, DeCaprio J, Shapiro GI, Chowdhury D, D'Andrea AD. CHK1 Inhibitor Blocks Phosphorylation of FAM122A and Promotes Replication Stress. Mol Cell. 2020 11 05; 80(3):410-422.e6. PMID: 33108758.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  2. Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, Zheng XF, Flynn HR, Snijders AP, Chowdhury D, Cesare AJ, Boulton SJ. CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle. Nature. 2019 11; 575(7783):523-527. PMID: 31723267; PMCID: PMC6874499.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  3. Zheng XF, Acharya SS, Choe KN, Nikhil K, Adelmant G, Satapathy SR, Sharma S, Viccaro K, Rana S, Natarajan A, Sicinski P, Marto JA, Shah K, Chowdhury D. A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1. Nat Commun. 2019 09 18; 10(1):4252. PMID: 31534152.
    Citations: 6     Fields:    Translation:HumansCells
  4. Drané P, Brault ME, Cui G, Meghani K, Chaubey S, Detappe A, Parnandi N, He Y, Zheng XF, Botuyan MV, Kalousi A, Yewdell WT, Münch C, Harper JW, Chaudhuri J, Soutoglou E, Mer G, Chowdhury D. TIRR regulates 53BP1 by masking its histone methyl-lysine binding function. Nature. 2017 03 09; 543(7644):211-216. PMID: 28241136.
    Citations: 53     Fields:    Translation:HumansAnimalsCells
  5. Xue X, Papusha A, Choi K, Bonner JN, Kumar S, Niu H, Kaur H, Zheng XF, Donnianni RA, Lu L, Lichten M, Zhao X, Ira G, Sung P. Differential regulation of the anti-crossover and replication fork regression activities of Mph1 by Mte1. Genes Dev. 2016 03 15; 30(6):687-99. PMID: 26966246.
    Citations: 14     Fields:    Translation:AnimalsCells
  6. Zheng XF, Kalev P, Chowdhury D. Emerging role of protein phosphatases changes the landscape of phospho-signaling in DNA damage response. DNA Repair (Amst). 2015 Aug; 32:58-65. PMID: 25956864.
    Citations: 12     Fields:    Translation:HumansCells
  7. Zhao Q, Saro D, Sachpatzidis A, Singh TR, Schlingman D, Zheng XF, Mack A, Tsai MS, Mochrie S, Regan L, Meetei AR, Sung P, Xiong Y. The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun. 2014; 5:2987. PMID: 24390579.
    Citations: 16     Fields:    Translation:HumansCells
  8. Daee DL, Ferrari E, Longerich S, Zheng XF, Xue X, Branzei D, Sung P, Myung K. Rad5-dependent DNA repair functions of the Saccharomyces cerevisiae FANCM protein homolog Mph1. J Biol Chem. 2012 Aug 03; 287(32):26563-75. PMID: 22696213; PMCID: PMC3410997.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  9. Islam MN, Paquet N, Fox D, Dray E, Zheng XF, Klein H, Sung P, Wang W. A variant of the breast cancer type 2 susceptibility protein (BRC) repeat is essential for the RECQL5 helicase to interact with RAD51 recombinase for genome stabilization. J Biol Chem. 2012 Jul 06; 287(28):23808-18. PMID: 22645136.
    Citations: 26     Fields:    Translation:HumansAnimalsCells
  10. Beaucher M, Zheng XF, Amariei F, Rong YS. Multiple pathways suppress telomere addition to DNA breaks in the Drosophila germline. Genetics. 2012 Jun; 191(2):407-17. PMID: 22446318; PMCID: PMC3374307.
    Citations: 15     Fields:    Translation:AnimalsCells
  11. Zheng XF, Prakash R, Saro D, Longerich S, Niu H, Sung P. Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protein. DNA Repair (Amst). 2011 Oct 10; 10(10):1034-43. PMID: 21880555.
    Citations: 43     Fields:    Translation:AnimalsCells
  12. Singh TR, Saro D, Ali AM, Zheng XF, Du CH, Killen MW, Sachpatzidis A, Wahengbam K, Pierce AJ, Xiong Y, Sung P, Meetei AR. MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM. Mol Cell. 2010 Mar 26; 37(6):879-86. PMID: 20347429.
    Citations: 119     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.