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Kate Jeffrey, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI144877 (JEFFREY, KATE LOUISA) Feb 6, 2019 - Jan 31, 2021
    NIH/NIAID
    Distinguishing immunomodulatory intestinal viruses through examination of viruses attached to RIG-I and MDA-5
    Role: Principal Investigator
  2. R01DK119996 (JEFFREY, KATE LOUISA) Sep 20, 2018 - Aug 31, 2022
    NIH/NIDDK
    Understanding the role of Epigenetic Reader SP140 in IBD
    Role: Principal Investigator
  3. R01AI107087 (JEFFREY, KATE LOUISA) Jul 1, 2014 - Jun 30, 2019
    NIH/NIAID
    Argonaute proteins in the mammalian antiviral response
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Murano T, Najibi M, Paulus GLC, Adiliaghdam F, Valencia-Guerrero A, Selig M, Wang X, Jeffrey K, Xavier RJ, Lassen KG, Irazoqui JE. Transcription factor TFEB cell-autonomously modulates susceptibility to intestinal epithelial cell injury in vivo. Sci Rep. 2017 10 24; 7(1):13938. PMID: 29066772.
    Citations:    Fields:    
  2. Jeffrey KL, Li Y, Ding SW. Reply to 'Questioning antiviral RNAi in mammals'. Nat Microbiol. 2017 04 25; 2:17053. PMID: 28440274.
    Citations: 2     Fields:    
  3. Mehta S, Cronkite DA, Basavappa M, Saunders TL, Adiliaghdam F, Amatullah H, Morrison SA, Pagan JD, Anthony RM, Tonnerre P, Lauer GM, Lee JC, Digumarthi S, Pantano L, Ho Sui SJ, Ji F, Sadreyev R, Zhou C, Mullen AC, Kumar V, Li Y, Wijmenga C, Xavier RJ, Means TK, Jeffrey KL. Maintenance of macrophage transcriptional programs and intestinal homeostasis by epigenetic reader SP140. Sci Immunol. 2017 Mar 03; 2(9). PMID: 28783698.
    Citations: 2     Fields:    
  4. Fusco DN, Pratt H, Kandilas S, Cheon SS, Lin W, Cronkite DA, Basavappa M, Jeffrey KL, Anselmo A, Sadreyev R, Yapp C, Shi X, O'Sullivan JF, Gerszten RE, Tomaru T, Yoshino S, Satoh T, Chung RT. HELZ2 Is an IFN Effector Mediating Suppression of Dengue Virus. Front Microbiol. 2017; 8:240. PMID: 28265266.
    Citations:    
  5. Li Y, Basavappa M, Lu J, Dong S, Cronkite DA, Prior JT, Reinecker HC, Hertzog P, Han Y, Li WX, Cheloufi S, Karginov FV, Ding SW, Jeffrey KL. Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells. Nat Microbiol. 2016 Dec 05; 2:16250. PMID: 27918527.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  6. Bandyopadhaya A, Tsurumi A, Maura D, Jeffrey KL, Rahme LG. A quorum-sensing signal promotes host tolerance training through HDAC1-mediated epigenetic reprogramming. Nat Microbiol. 2016 Oct 03; 1:16174. PMID: 27694949.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  7. Mehta S, Jeffrey KL. Beyond receptors and signaling: epigenetic factors in the regulation of innate immunity. Immunol Cell Biol. 2015 Mar; 93(3):233-44. PMID: 25559622.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  8. Chiang HS, Zhao Y, Song JH, Liu S, Wang N, Terhorst C, Sharpe AH, Basavappa M, Jeffrey KL, Reinecker HC. GEF-H1 controls microtubule-dependent sensing of nucleic acids for antiviral host defenses. Nat Immunol. 2014 Jan; 15(1):63-71. PMID: 24270516.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  9. Marazzi I, Ho JS, Kim J, Manicassamy B, Dewell S, Albrecht RA, Seibert CW, Schaefer U, Jeffrey KL, Prinjha RK, Lee K, García-Sastre A, Roeder RG, Tarakhovsky A. Suppression of the antiviral response by an influenza histone mimic. Nature. 2012 Mar 14; 483(7390):428-33. PMID: 22419161.
    Citations: 88     Fields:    Translation:HumansCells
  10. Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung CW, Chandwani R, Marazzi I, Wilson P, Coste H, White J, Kirilovsky J, Rice CM, Lora JM, Prinjha RK, Lee K, Tarakhovsky A. Suppression of inflammation by a synthetic histone mimic. Nature. 2010 Dec 23; 468(7327):1119-23. PMID: 21068722.
    Citations: 424     Fields:    Translation:AnimalsCells
  11. Cheong C, Matos I, Choi JH, Dandamudi DB, Shrestha E, Longhi MP, Jeffrey KL, Anthony RM, Kluger C, Nchinda G, Koh H, Rodriguez A, Idoyaga J, Pack M, Velinzon K, Park CG, Steinman RM. Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell. 2010 Oct 29; 143(3):416-29. PMID: 21029863.
    Citations: 229     Fields:    Translation:AnimalsCells
  12. Yang JS, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, Papapetrou EP, Sadelain M, O'Carroll D, Lai EC. Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc Natl Acad Sci U S A. 2010 Aug 24; 107(34):15163-8. PMID: 20699384.
    Citations: 157     Fields:    Translation:HumansAnimalsCells
  13. Jeffrey K. Rechallenging immunological memory. Nat Med. 2007 Oct; 13(10):1142. PMID: 17917658.
    Citations: 1     Fields:    Translation:AnimalsCells
  14. Jeffrey KL, Camps M, Rommel C, Mackay CR. Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nat Rev Drug Discov. 2007 May; 6(5):391-403. PMID: 17473844.
    Citations: 147     Fields:    Translation:HumansAnimalsCells
  15. Jeffrey KL, Brummer T, Rolph MS, Liu SM, Callejas NA, Grumont RJ, Gillieron C, Mackay F, Grey S, Camps M, Rommel C, Gerondakis SD, Mackay CR. Positive regulation of immune cell function and inflammatory responses by phosphatase PAC-1. Nat Immunol. 2006 Mar; 7(3):274-83. PMID: 16474395.
    Citations: 82     Fields:    Translation:HumansAnimalsCells
  16. Moffatt JD, Jeffrey KL, Cocks TM. Protease-activated receptor-2 activating peptide SLIGRL inhibits bacterial lipopolysaccharide-induced recruitment of polymorphonuclear leukocytes into the airways of mice. Am J Respir Cell Mol Biol. 2002 Jun; 26(6):680-4. PMID: 12034566.
    Citations: 24     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.