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Javier Andres Villafuerte Galvez, M.D.

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Biography
Universidad Peruana Cayetano Heredia, Lima, PeruMD03/2011Medicine
Beth Israel Deaconess Medical Center, Boston, MA09/2013Research Fellowship in Gastroenterology
Beth Israel Deaconess Medical Center, Boston, MA09/2016Internal Medicine
Harvard Medical School , Boston, MA2018Certificate in Applied Biostatistics
Beth Israel Deaconess Medical Center, Boston, MA10/2021Fellowship in Gastroenterology, Hepatology and Nutrition
2016
"Nuestras Estrellas" Award for Advancing the Care of Latino Patients
2020
Award in recognition of extraordinary efforts during the COVID-19 pandemic

Overview
My research and clinical practice focus on patients with immune-mediated disease of the digestive tract. I have had broad exposure and training in internal medicine and gastroenterology. I have specific expertise and interest in analysis and integration of highly dimensional biological marker datasets and patient level clinical outcomes, specifically immune markers; for which I intend to pursue further formal training and hands-on mentored experience. During my training, I have collaborated with various groups in areas within my interest including global health, inflammatory bowel disease, celiac disease and Clostridioides difficile infection. Key skills acquired include clinical expertise, establishment and maintenance of collaborations, balancing of clinical and research duties, critical data analysis and troubleshooting, construction and revision of research products, among others. This has led to multiple peer reviewed articles, the granting of my faculty position and has laid the groundwork for a period of mentored career development to continue my transition towards being an independent researcher

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Alonso CD, Pollock NR, Garey KW, Gonzales-Luna AJ, Williams DN, Daugherty K, Cuddemi C, Villafuerte-Gálvez J, White NC, Chen X, Xu H, Sprague R, Barrett C, Miller M, Foussadier A, Lantz A, Banz A, Kelly CP. Higher In Vivo Fecal Concentrations of Clostridioides difficile Toxins A and B in Patients With North American Pulsed-Field Gel Electrophoresis Type 1/Ribotype 027 Strain Infection. Clin Infect Dis. 2022 11 30; 75(11):2019-2022. PMID: 35607815.
    Citations:    Fields:    
  2. Cao Y, Wang L, Ke S, Kelly CP, Pollock NR, Villafuerte Gálvez JA, Daugherty K, Xu H, Yao J, Chen Y, Liu YY, Chen X. Analysis of Intestinal Mycobiota of Patients with Clostridioides difficile Infection among a Prospective Inpatient Cohort. Microbiol Spectr. 2022 08 31; 10(4):e0136222. PMID: 35867408; PMCID: PMC9430669.
    Citations:    Fields:    
  3. Alonso CD, Kelly CP, Garey KW, Gonzales-Luna AJ, Williams D, Daugherty K, Cuddemi C, Villafuerte-Gálvez J, White NC, Chen X, Xu H, Sprague R, Barrett C, Miller M, Foussadier A, Lantz A, Banz A, Pollock NR. Ultrasensitive and Quantitative Toxin Measurement Correlates With Baseline Severity, Severe Outcomes, and Recurrence Among Hospitalized Patients With Clostridioides difficile Infection. Clin Infect Dis. 2022 07 06; 74(12):2142-2149. PMID: 34537841; PMCID: PMC9258941.
    Citations:    Fields:    Translation:HumansCells
  4. Villafuerte-Gálvez JA, Silvester JA. Dating While Gluten-Free-Don't Kiss and Don't Tell? Dig Dis Sci. 2022 11; 67(11):4976-4978. PMID: 35635629.
    Citations:    Fields:    
  5. Silva-Santisteban A, Agnihotri A, Cruz-Romero C, Nasser IA, Malvar GL, Nsubuga JP, Villafuerte Gálvez JA, Bonder A, Pleskow DK, Berzin TM, Sawhney MS. EUS imaging for the diagnosis of nonalcoholic fatty liver disease. Gastrointest Endosc. 2022 Apr; 95(4):711-716. PMID: 34915035.
    Citations: 1     Fields:    Translation:Humans
  6. Villafuerte-Gálvez JA. Proton Pump Inhibitors and Incident Clostridioides difficile Infection: Beyond Controversy, Pragmatic Approaches Are Needed. Clin Infect Dis. 2021 06 15; 72(12):e1090-e1092. PMID: 33320187.
    Citations:    Fields:    Translation:HumansCells
  7. Alonso CD, Papamichael K, Sprague R, Barrett C, Gonzales-Luna AJ, Daugherty K, Garey KW, Villafuerte-Gálvez J, Xu H, Lin Q, Wang L, Chen X, Pollock NR, Kelly CP. Humoral Immune Response to Clostridioides difficile Toxins A and B in Hospitalized Immunocompromised Patients With C difficile Infection. Open Forum Infect Dis. 2021 Jul; 8(7):ofab286. PMID: 34258317; PMCID: PMC8271131.
    Citations:    
  8. Cao Y, Wang L, Ke S, Villafuerte Gálvez JA, Pollock NR, Barrett C, Sprague R, Daugherty K, Xu H, Lin Q, Yao J, Chen Y, Kelly CP, Liu YY, Chen X. Fecal Mycobiota Combined With Host Immune Factors Distinguish Clostridioides difficile Infection From Asymptomatic Carriage. Gastroenterology. 2021 06; 160(7):2328-2339.e6. PMID: 33684427; PMCID: PMC8169571.
    Citations: 7     Fields:    Translation:HumansCells
  9. Villafuerte Gálvez JA, Silvester JA. Safety of a GFD in Pregnant Women Without Celiac Disease: Investigating Ingrained Habits. Dig Dis Sci. 2020 10; 65(10):2751-2753. PMID: 32651744; PMCID: PMC7494618.
    Citations:    Fields:    Translation:Humans
  10. Mendo-Lopez R, Villafuerte-Gálvez J, White N, Mahoney MV, Kelly CP, Alonso CD. Recent developments in the management of recurrent Clostridioides difficile infection. Anaerobe. 2020 Apr; 62:102108. PMID: 31606481.
    Citations: 3     Fields:    Translation:HumansCells
  11. Huang J, Kelly CP, Bakirtzi K, Villafuerte Gálvez JA, Lyras D, Mileto SJ, Larcombe S, Xu H, Yang X, Shields KS, Zhu W, Zhang Y, Goldsmith JD, Patel IJ, Hansen J, Huang M, Yla-Herttuala S, Moss AC, Paredes-Sabja D, Pothoulakis C, Shah YM, Wang J, Chen X. Clostridium difficile toxins induce VEGF-A and vascular permeability to promote disease pathogenesis. Nat Microbiol. 2019 02; 4(2):269-279. PMID: 30510170; PMCID: PMC6559218.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  12. Villafuerte-Gálvez JA, Kelly CP. Proton pump inhibitors and risk of Clostridium difficile infection: association or causation? Curr Opin Gastroenterol. 2018 Jan; 34(1):11-18. PMID: 29095766.
    Citations: 5     Fields:    Translation:HumansCells
  13. Villafuerte Gálvez JA, Kelly CP. Bezlotoxumab: anti-toxin B monoclonal antibody to prevent recurrence of Clostridium difficile infection. Expert Rev Gastroenterol Hepatol. 2017 Jul; 11(7):611-622. PMID: 28636484.
    Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  14. Kabbani TA, Pallav K, Dowd SE, Villafuerte-Galvez J, Vanga RR, Castillo NE, Hansen J, Dennis M, Leffler DA, Kelly CP. Prospective randomized controlled study on the effects of Saccharomyces boulardii CNCM I-745 and amoxicillin-clavulanate or the combination on the gut microbiota of healthy volunteers. Gut Microbes. 2017 01 02; 8(1):17-32. PMID: 27973989.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  15. Patel I, Wungjiranirun M, Theethira T, Villafuerte-Galvez J, Castillo N, Akbari M, Alonso CD, Leffler DA, Kelly CP. Lack of adherence to SHEA-IDSA treatment guidelines for Clostridium difficile infection is associated with increased mortality. J Antimicrob Chemother. 2017 02; 72(2):574-581. PMID: 28115504; PMCID: PMC6074846.
    Citations: 7     Fields:    Translation:HumansCells
  16. Villafuerte-Galvez J, Vanga RR, Dennis M, Hansen J, Leffler DA, Kelly CP, Mukherjee R. Factors governing long-term adherence to a gluten-free diet in adult patients with coeliac disease. Aliment Pharmacol Ther. 2015 Sep; 42(6):753-60. PMID: 26206401.
    Citations: 24     Fields:    Translation:Humans
  17. Castillo NE, Vanga RR, Theethira TG, Rubio-Tapia A, Murray JA, Villafuerte J, Bonder A, Mukherjee R, Hansen J, Dennis M, Kelly CP, Leffler DA. Prevalence of abnormal liver function tests in celiac disease and the effect of a gluten-free diet in the US population. Am J Gastroenterol. 2015 Aug; 110(8):1216-22. PMID: 26150087.
    Citations: 12     Fields:    Translation:Humans
  18. Gashin L, Villafuerte-Galvez J, Leffler DA, Obuch J, Cheifetz AS. Utility of CT in the emergency department in patients with ulcerative colitis. Inflamm Bowel Dis. 2015 Apr; 21(4):793-800. PMID: 25742397.
    Citations: 3     Fields:    Translation:Humans
  19. Pallav K, Dowd SE, Villafuerte J, Yang X, Kabbani T, Hansen J, Dennis M, Leffler DA, Newburg DS, Kelly CP. Effects of polysaccharopeptide from Trametes versicolor and amoxicillin on the gut microbiome of healthy volunteers: a randomized clinical trial. Gut Microbes. 2014 Jul 01; 5(4):458-67. PMID: 25006989.
    Citations: 22     Fields:    Translation:HumansAnimals
  20. Kabbani TA, Vanga RR, Leffler DA, Villafuerte-Galvez J, Pallav K, Hansen J, Mukherjee R, Dennis M, Kelly CP. Celiac disease or non-celiac gluten sensitivity? An approach to clinical differential diagnosis. Am J Gastroenterol. 2014 May; 109(5):741-6; quiz 747. PMID: 24619056.
    Citations: 25     Fields:    Translation:Humans
  21. Kabbani TA, Kelly CP, Betensky RA, Hansen J, Pallav K, Villafuerte-Gálvez JA, Vanga R, Mukherjee R, Novero A, Dennis M, Leffler DA. Patients with celiac disease have a lower prevalence of non-insulin-dependent diabetes mellitus and metabolic syndrome. Gastroenterology. 2013 May; 144(5):912-917.e1. PMID: 23354016; PMCID: PMC3755346.
    Citations: 15     Fields:    Translation:Humans
  22. Villafuerte-Gálvez J, Sotelo-Olivera MI, Cok J, Piscoya-Rivera A, Huerta-Mercado J. Colonoscopic findings in Peruvian patients with chronic diarrhea. PLoS One. 2012; 7(10):e46690. PMID: 23094029.
    Citations: 2     Fields:    Translation:Humans
  23. Machicado JD, Villafuerte-Galvez J, Marcos LA. Prevalence of irritable bowel syndrome in South America. Clin Gastroenterol Hepatol. 2013 Jan; 11(1):102. PMID: 22902775.
    Citations:    Fields:    Translation:Humans
  24. Peña-Oscuvilca A, Saldaña-Gastulo JJ, Villafuerte-Gálvez J, Paz-Marchena A, Alvarado-Gamarra AG. [Considering scientific publications for the entry to the medical residency in Peru]. Rev Peru Med Exp Salud Publica. 2010 Oct-Dec; 27(4):650-2. PMID: 21308211.
    Citations:    Fields:    
  25. Villafuerte-Gálvez J. [Impact of direct link to full-text articles from gastroenterological journals in PubMed]. Rev Gastroenterol Peru. 2009 Jan-Mar; 29(1):75-6. PMID: 19424413.
    Citations:    Fields:    
  26. Villafuerte-Galvez J, Curioso WH, Miranda JJ. The role of medical students in the fight to control neglected tropical diseases: a view from Peru. PLoS Negl Trop Dis. 2008 Sep 24; 2(9):e292. PMID: 18836555.
    Citations: 2     Fields:    Translation:HumansAnimals
  27. Villafuerte-Galvez J, Curioso WH. Teaching global health at the frontlines. A multidisciplinary course in Peru presents basic concepts to students. PLoS Med. 2007 Jun; 4(6):e130. PMID: 17550301; PMCID: PMC1885452.
    Citations: 7     Fields:    Translation:Humans
  28. Villafuerte-Gálvez J, Curioso WH, Gayoso O. Biomedical journals and global poverty: is HINARI a step backwards? PLoS Med. 2007 Jun; 4(6):e220. PMID: 17594171; PMCID: PMC1896213.
    Citations: 14     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.