Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Nicholas Stylopoulos, M.D.

Profile Picture


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R56DK125816 (STYLOPOULOS, NICHOLAS) Aug 1, 2020 - Jul 31, 2021
    Intestinal Mechanisms and Molecular Predictors of Type 2 Diabetes Remission After Roux-en-Y Gastric Bypass Surgery
    Role: Principal Investigator
  2. R21OD029996 (STYLOPOULOS, NICHOLAS) Jul 1, 2020 - Jun 30, 2022
    The Burmese Python as a Model System for the Study of Metabolism and Organ Regeneration
    Role: Principal Investigator
  3. R01DK108642 (STYLOPOULOS, NICHOLAS) Sep 24, 2015 - Aug 31, 2020
    Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Saeidi N, Stefater M, Stylopoulos N. Effect of Diet versus Gastric Bypass on Metabolic Function in Diabetes. N Engl J Med. 2020 12 10; 383(24):2391-2392. PMID: 33296570.
    Citations:    Fields:    Translation:Humans
  2. Ryou M, Stylopoulos N. Endoscopic ultrasound-guided sampling and profiling of portal circulation in human patients for metabolic research studies and biomarker assessment. Am J Physiol Gastrointest Liver Physiol. 2020 11 01; 319(5):G584-G588. PMID: 32877219.
    Citations: 1     Fields:    Translation:Humans
  3. Ryou M, Stylopoulos N, Baffy G. Nonalcoholic fatty liver disease and portal hypertension. Explor Med. 2020; 1:149-169. PMID: 32685936.
    Citations: 5     
  4. Stefater MA, Pacheco JA, Bullock K, Pierce K, Deik A, Liu E, Clish C, Stylopoulos N. Portal Venous Metabolite Profiling After RYGB in Male Rats Highlights Changes in Gut-Liver Axis. J Endocr Soc. 2020 Feb 01; 4(2):bvaa003. PMID: 32099946.
  5. Abidi W, Nestoridi E, Feldman H, Stefater M, Clish C, Thompson CC, Stylopoulos N. Differential Metabolomic Signatures in Patients with Weight Regain and Sustained Weight Loss After Gastric Bypass Surgery: A Pilot Study. Dig Dis Sci. 2020 04; 65(4):1144-1154. PMID: 31385097.
    Citations: 7     Fields:    Translation:Humans
  6. Martinez EE, Panciotti C, Pereira LM, Kellogg MD, Stylopoulos N, Mehta NM. Gastrointestinal Hormone Profiles Associated With Enteral Nutrition Tolerance and Gastric Emptying in Pediatric Critical Illness: A Pilot Study. JPEN J Parenter Enteral Nutr. 2020 03; 44(3):472-480. PMID: 31304610.
    Citations:    Fields:    Translation:Humans
  7. Meoli L, Ben-Zvi D, Panciotti C, Kvas S, Pizarro P, Munoz R, Stylopoulos N. Intestine-Specific Overexpression of LDLR Enhances Cholesterol Excretion and Induces Metabolic Changes in Male Mice. Endocrinology. 2019 04 01; 160(4):744-758. PMID: 30566603.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  8. Courcoulas AP, Stefater MA, Shirley E, Gourash WF, Stylopoulos N. The Feasibility of Examining the Effects of Gastric Bypass Surgery on Intestinal Metabolism: Prospective, Longitudinal Mechanistic Clinical Trial. JMIR Res Protoc. 2019 Jan 24; 8(1):e12459. PMID: 30679147.
  9. Tao R, Wang C, Stöhr O, Qiu W, Hu Y, Miao J, Dong XC, Leng S, Stefater M, Stylopoulos N, Lin L, Copps KD, White MF. Publisher Correction: Inactivating hepatic follistatin alleviates hyperglycemia. Nat Med. 2018 Oct; 24(10):1628. PMID: 30111893.
    Citations:    Fields:    
  10. Ben-Zvi D, Meoli L, Abidi WM, Nestoridi E, Panciotti C, Castillo E, Pizarro P, Shirley E, Gourash WF, Thompson CC, Munoz R, Clish CB, Anafi RC, Courcoulas AP, Stylopoulos N. Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species. Cell Metab. 2018 08 07; 28(2):310-323.e6. PMID: 30043755.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  11. Tao R, Wang C, Stöhr O, Qiu W, Hu Y, Miao J, Dong XC, Leng S, Stefater M, Stylopoulos N, Lin L, Copps KD, White MF. Inactivating hepatic follistatin alleviates hyperglycemia. Nat Med. 2018 07; 24(7):1058-1069. PMID: 29867232.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  12. Meoli L, Gupta NK, Saeidi N, Panciotti CA, Biddinger SB, Corey KE, Stylopoulos N. Nonalcoholic fatty liver disease and gastric bypass surgery regulate serum and hepatic levels of pyruvate kinase isoenzyme M2. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E613-E621. PMID: 29462566.
    Citations: 4     Fields:    Translation:HumansAnimals
  13. Zaytouni T, Tsai PY, Hitchcock DS, DuBois CD, Freinkman E, Lin L, Morales-Oyarvide V, Lenehan PJ, Wolpin BM, Mino-Kenudson M, Torres EM, Stylopoulos N, Clish CB, Kalaany NY. Critical role for arginase 2 in obesity-associated pancreatic cancer. Nat Commun. 2017 08 14; 8(1):242. PMID: 28808255.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  14. Mumphrey MB, Hao Z, Townsend RL, Patterson LM, Morrison CD, Münzberg H, Stylopoulos N, Ye J, Berthoud HR. Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade. Obesity (Silver Spring). 2014 Aug; 22(8):1847-53. PMID: 24799258.
    Citations: 11     Fields:    Translation:Animals
  15. Ye J, Hao Z, Mumphrey MB, Townsend RL, Patterson LM, Stylopoulos N, Münzberg H, Morrison CD, Drucker DJ, Berthoud HR. GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents. Am J Physiol Regul Integr Comp Physiol. 2014 Mar 01; 306(5):R352-62. PMID: 24430883.
    Citations: 86     Fields:    Translation:Animals
  16. Saeidi N, Meoli L, Nestoridi E, Gupta NK, Kvas S, Kucharczyk J, Bonab AA, Fischman AJ, Yarmush ML, Stylopoulos N. Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass. Science. 2013 Jul 26; 341(6144):406-10. PMID: 23888041.
    Citations: 146     Fields:    Translation:AnimalsCells
  17. Saeidi N, Nestoridi E, Kucharczyk J, Uygun MK, Yarmush ML, Stylopoulos N. Sleeve gastrectomy and Roux-en-Y gastric bypass exhibit differential effects on food preferences, nutrient absorption and energy expenditure in obese rats. Int J Obes (Lond). 2012 Nov; 36(11):1396-402. PMID: 23044855.
    Citations: 42     Fields:    Translation:Animals
  18. Muñoz R, Carmody JS, Stylopoulos N, Davis P, Kaplan LM. Isolated duodenal exclusion increases energy expenditure and improves glucose homeostasis in diet-induced obese rats. Am J Physiol Regul Integr Comp Physiol. 2012 Nov 15; 303(10):R985-93. PMID: 22972837.
    Citations: 11     Fields:    Translation:Animals
  19. Hatoum IJ, Stylopoulos N, Vanhoose AM, Boyd KL, Yin DP, Ellacott KL, Ma LL, Blaszczyk K, Keogh JM, Cone RD, Farooqi IS, Kaplan LM. Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery. J Clin Endocrinol Metab. 2012 Jun; 97(6):E1023-31. PMID: 22492873.
    Citations: 73     Fields:    Translation:HumansAnimalsCells
  20. Nestoridi E, Kvas S, Kucharczyk J, Stylopoulos N. Resting energy expenditure and energetic cost of feeding are augmented after Roux-en-Y gastric bypass in obese mice. Endocrinology. 2012 May; 153(5):2234-44. PMID: 22416083.
    Citations: 52     Fields:    Translation:Animals
  21. Kucharczyk J, Nestoridi E, Kvas S, Andrews R, Stylopoulos N. Probing the mechanisms of the metabolic effects of weight loss surgery in humans using a novel mouse model system. J Surg Res. 2013 Jan; 179(1):e91-8. PMID: 22504136.
    Citations: 10     Fields:    Translation:HumansAnimals
  22. Stylopoulos N, Aguirre V. Mechanisms of bariatric surgery and implications for the development of endoluminal therapies for obesity. Gastrointest Endosc. 2009 Dec; 70(6):1167-75. PMID: 19560763.
    Citations: 4     Fields:    Translation:Humans
  23. Stylopoulos N, Hoppin AG, Kaplan LM. Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats. Obesity (Silver Spring). 2009 Oct; 17(10):1839-47. PMID: 19556976.
    Citations: 95     Fields:    Translation:Animals
  24. Aguirre V, Stylopoulos N, Grinbaum R, Kaplan LM. An endoluminal sleeve induces substantial weight loss and normalizes glucose homeostasis in rats with diet-induced obesity. Obesity (Silver Spring). 2008 Dec; 16(12):2585-92. PMID: 19279655.
    Citations: 32     Fields:    Translation:AnimalsCells
  25. Estépar RS, Stylopoulos N, Ellis R, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic ultrasound navigation system for transgastric access procedures. Comput Aided Surg. 2007 Nov; 12(6):311-24. PMID: 18066947.
    Citations: 10     Fields:    Translation:Humans
  26. Stylopoulos N, Vosburgh KG. Assessing technical skill in surgery and endoscopy: a set of metrics and an algorithm (C-PASS) to assess skills in surgical and endoscopic procedures. Surg Innov. 2007 Jun; 14(2):113-21. PMID: 17558017.
    Citations: 9     Fields:    Translation:Humans
  27. Vosburgh KG, Stylopoulos N, Estepar RS, Ellis RE, Samset E, Thompson CC. EUS with CT improves efficiency and structure identification over conventional EUS. Gastrointest Endosc. 2007 May; 65(6):866-70. PMID: 17466206.
    Citations: 9     Fields:    Translation:Animals
  28. San José Estépar R, Stylopoulos N, Ellis RE, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic-ultrasound navigation system for transgastric access procedures. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):445-53. PMID: 17354921.
    Citations: 3     Fields:    Translation:Humans
  29. Maithel SK, Stylopoulos N, Jones DB, Rattner DW, Kaplan LM. Intact Leptin Signaling Is Required for Changes in Food Intake After Roux-en-Y Gastric Bypass in Rats. Digestive Disease Week, Chicago, IL, USA. 2005.
  30. Stylopoulos N, Davis P, Pettit JD, Rattner DW, Kaplan LM. Changes in serum ghrelin predict weight loss after Roux-en-Y gastric bypass in rats. Surg Endosc. 2005 Jul; 19(7):942-6. PMID: 15920683.
    Citations: 23     Fields:    Translation:Animals
  31. Stylopoulos N, Rattner DW. The history of hiatal hernia surgery: from Bowditch to laparoscopy. Ann Surg. 2005 Jan; 241(1):185-93. PMID: 15622007.
    Citations: 48     Fields:    Translation:Humans
  32. Maithel SK, Villegas L, Stylopoulos N, Dawson S, Jones DB. Simulated laparoscopy using a head-mounted display vs traditional video monitor: an assessment of performance and muscle fatigue. Surg Endosc. 2005 Mar; 19(3):406-11. PMID: 15624063.
    Citations: 19     Fields:    
  33. Stylopoulos N, Cotin S, Maithel SK, Ottensmeye M, Jackson PG, Bardsley RS, Neumann PF, Rattner DW, Dawson SL. Computer-enhanced laparoscopic training system (CELTS): bridging the gap. Surg Endosc. 2004 May; 18(5):782-9. PMID: 15216861.
    Citations: 16     Fields:    Translation:Humans
  34. Stylopoulos N, Rattner D. Robotics and ergonomics. Surg Clin North Am. 2003 Dec; 83(6):1321-37. PMID: 14712869.
    Citations: 21     Fields:    Translation:Humans
  35. Sims C, Stylopoulos N, Clavijo J, Barlow C. Histologic characteristics of laparoscopic saline-enhanced electrosurgery of liver and splenic injuries. Surg Endosc. 2003 Nov; 17(11):1739-43. PMID: 12739124.
    Citations:    Fields:    Translation:Animals
  36. Cotin S, Stylopoulos N, Neumann P, Ottensmeyer M, Dawson S. A software based implementation for evaluating surgical performance using kinematic analysis. 2003.
  37. Stylopoulos N, Cotin S, Dawson S, Ottensmeyer M, Neumann P, Bardsley R, Russell M, Jackson P, Rattner D. CELTS: a clinically-based Computer Enhanced Laparoscopic Training System. Stud Health Technol Inform. 2003; 94:336-42. PMID: 15455919.
    Citations: 3     Fields:    
  38. Stylopoulos N, Rattner DW. Paraesophageal hernia: when to operate? Adv Surg. 2003; 37:213-29. PMID: 12953635.
    Citations: 5     Fields:    Translation:Humans
  39. Stylopoulos N, Gazelle GS, Rattner DW. A cost--utility analysis of treatment options for inguinal hernia in 1,513,008 adult patients. Surg Endosc. 2003 Feb; 17(2):180-9. PMID: 12415334.
    Citations: 30     Fields:    Translation:Humans
  40. Stylopoulos N, Gazelle GS, Rattner DW. Paraesophageal hernias: operation or observation? Ann Surg. 2002 Oct; 236(4):492-500; discussion 500-1. PMID: 12368678.
    Citations: 102     Fields:    Translation:Humans
  41. Stylopoulos N, Bunker CJ, Rattner DW. Development of achalasia secondary to laparoscopic Nissen fundoplication. J Gastrointest Surg. 2002 May-Jun; 6(3):368-76; discussion 377-78. PMID: 12022989.
    Citations: 16     Fields:    Translation:Humans
  42. Tay BK, Stylopoulos N, De S, Rattner DW, Srinivasan MA. Measurement of in-vivo force response of intra-abdominal soft tissues for surgical simulation. Stud Health Technol Inform. 2002; 85:514-9. PMID: 15458143.
    Citations: 1     Fields:    Translation:HumansAnimals
  43. Linos DA, Stylopoulos N. How accurate is computed tomography in predicting the real size of adrenal tumors? A retrospective study. Arch Surg. 1997 Jul; 132(7):740-3. PMID: 9230858.
    Citations: 5     Fields:    Translation:Humans
  44. Linos DA, Stylopoulos N, Boukis M, Souvatzoglou A, Raptis S, Papadimitriou J. Anterior, posterior, or laparoscopic approach for the management of adrenal diseases? Am J Surg. 1997 Feb; 173(2):120-5. PMID: 9074377.
    Citations: 16     Fields:    Translation:Humans
  45. Linos DA, Stylopoulos N, Raptis SA. Adrenaloma: a call for more aggressive management. World J Surg. 1996 Sep; 20(7):788-92; discussion 792-3. PMID: 8678952.
    Citations: 11     Fields:    Translation:Humans
  46. Ferreiro JA, Stylopoulos N. Oncocytic differentiation in salivary gland tumours. J Laryngol Otol. 1995 Jun; 109(6):569-71. PMID: 7643006.
    Citations: 3     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Stylopoulos's Networks
Click the
buttons for more information and interactive visualizations!
Concepts (245)
Co-Authors (27)
Similar People (60)
Same Department 
Physical Neighbors
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.