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Nicholas Stylopoulos, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DK108642 (STYLOPOULOS, NICHOLAS) Sep 24, 2015 - Aug 31, 2020
    NIH/NIDDK
    Intestinal Metabolic Reprogramming as a Key Mechanism of Gastric Bypass in Humans
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Meoli L, Ben-Zvi D, Panciotti C, Kvas S, Pizarro P, Munoz R, Stylopoulos N. Intestine-Specific Overexpression of LDLR Enhances Cholesterol Excretion and Induces Metabolic Changes in Male Mice. Endocrinology. 2019 Apr 01; 160(4):744-758. PMID: 30566603.
    Citations:    Fields:    
  2. Courcoulas AP, Stefater MA, Shirley E, Gourash WF, Stylopoulos N. The Feasibility of Examining the Effects of Gastric Bypass Surgery on Intestinal Metabolism: Prospective, Longitudinal Mechanistic Clinical Trial. JMIR Res Protoc. 2019 Jan 24; 8(1):e12459. PMID: 30679147.
    Citations:    
  3. Tao R, Wang C, Stöhr O, Qiu W, Hu Y, Miao J, Dong XC, Leng S, Stefater M, Stylopoulos N, Lin L, Copps KD, White MF. Publisher Correction: Inactivating hepatic follistatin alleviates hyperglycemia. Nat Med. 2018 Oct; 24(10):1628. PMID: 30111893.
    Citations:    Fields:    
  4. Ben-Zvi D, Meoli L, Abidi WM, Nestoridi E, Panciotti C, Castillo E, Pizarro P, Shirley E, Gourash WF, Thompson CC, Munoz R, Clish CB, Anafi RC, Courcoulas AP, Stylopoulos N. Time-Dependent Molecular Responses Differ between Gastric Bypass and Dieting but Are Conserved Across Species. Cell Metab. 2018 Aug 07; 28(2):310-323.e6. PMID: 30043755.
    Citations:    Fields:    
  5. Tao R, Wang C, Stöhr O, Qiu W, Hu Y, Miao J, Dong XC, Leng S, Stefater M, Stylopoulos N, Lin L, Copps KD, White MF. Inactivating hepatic follistatin alleviates hyperglycemia. Nat Med. 2018 07; 24(7):1058-1069. PMID: 29867232.
    Citations: 1     Fields:    
  6. Meoli L, Gupta NK, Saeidi N, Panciotti CA, Biddinger SB, Corey KE, Stylopoulos N. Nonalcoholic fatty liver disease and gastric bypass surgery regulate serum and hepatic levels of pyruvate kinase isoenzyme M2. Am J Physiol Endocrinol Metab. 2018 10 01; 315(4):E613-E621. PMID: 29462566.
    Citations:    Fields:    
  7. Zaytouni T, Tsai PY, Hitchcock DS, DuBois CD, Freinkman E, Lin L, Morales-Oyarvide V, Lenehan PJ, Wolpin BM, Mino-Kenudson M, Torres EM, Stylopoulos N, Clish CB, Kalaany NY. Critical role for arginase 2 in obesity-associated pancreatic cancer. Nat Commun. 2017 08 14; 8(1):242. PMID: 28808255.
    Citations:    Fields:    Translation:HumansAnimalsCells
  8. Mumphrey MB, Hao Z, Townsend RL, Patterson LM, Morrison CD, Münzberg H, Stylopoulos N, Ye J, Berthoud HR. Reversible hyperphagia and obesity in rats with gastric bypass by central MC3/4R blockade. Obesity (Silver Spring). 2014 Aug; 22(8):1847-53. PMID: 24799258.
    Citations: 7     Fields:    Translation:Animals
  9. Ye J, Hao Z, Mumphrey MB, Townsend RL, Patterson LM, Stylopoulos N, Münzberg H, Morrison CD, Drucker DJ, Berthoud HR. GLP-1 receptor signaling is not required for reduced body weight after RYGB in rodents. Am J Physiol Regul Integr Comp Physiol. 2014 Mar 01; 306(5):R352-62. PMID: 24430883.
    Citations: 47     Fields:    Translation:Animals
  10. Saeidi N, Meoli L, Nestoridi E, Gupta NK, Kvas S, Kucharczyk J, Bonab AA, Fischman AJ, Yarmush ML, Stylopoulos N. Reprogramming of intestinal glucose metabolism and glycemic control in rats after gastric bypass. Science. 2013 Jul 26; 341(6144):406-10. PMID: 23888041.
    Citations: 86     Fields:    Translation:AnimalsCells
  11. Saeidi N, Nestoridi E, Kucharczyk J, Uygun MK, Yarmush ML, Stylopoulos N. Sleeve gastrectomy and Roux-en-Y gastric bypass exhibit differential effects on food preferences, nutrient absorption and energy expenditure in obese rats. Int J Obes (Lond). 2012 Nov; 36(11):1396-402. PMID: 23044855.
    Citations: 26     Fields:    Translation:Animals
  12. Muñoz R, Carmody JS, Stylopoulos N, Davis P, Kaplan LM. Isolated duodenal exclusion increases energy expenditure and improves glucose homeostasis in diet-induced obese rats. Am J Physiol Regul Integr Comp Physiol. 2012 Nov 15; 303(10):R985-93. PMID: 22972837.
    Citations: 10     Fields:    Translation:Animals
  13. Hatoum IJ, Stylopoulos N, Vanhoose AM, Boyd KL, Yin DP, Ellacott KL, Ma LL, Blaszczyk K, Keogh JM, Cone RD, Farooqi IS, Kaplan LM. Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery. J Clin Endocrinol Metab. 2012 Jun; 97(6):E1023-31. PMID: 22492873.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  14. Nestoridi E, Kvas S, Kucharczyk J, Stylopoulos N. Resting energy expenditure and energetic cost of feeding are augmented after Roux-en-Y gastric bypass in obese mice. Endocrinology. 2012 May; 153(5):2234-44. PMID: 22416083.
    Citations: 35     Fields:    Translation:Animals
  15. Kucharczyk J, Nestoridi E, Kvas S, Andrews R, Stylopoulos N. Probing the mechanisms of the metabolic effects of weight loss surgery in humans using a novel mouse model system. J Surg Res. 2013 Jan; 179(1):e91-8. PMID: 22504136.
    Citations: 7     Fields:    Translation:HumansAnimals
  16. Stylopoulos N, Aguirre V. Mechanisms of bariatric surgery and implications for the development of endoluminal therapies for obesity. Gastrointest Endosc. 2009 Dec; 70(6):1167-75. PMID: 19560763.
    Citations: 3     Fields:    Translation:Humans
  17. Stylopoulos N, Hoppin AG, Kaplan LM. Roux-en-Y gastric bypass enhances energy expenditure and extends lifespan in diet-induced obese rats. Obesity (Silver Spring). 2009 Oct; 17(10):1839-47. PMID: 19556976.
    Citations: 85     Fields:    Translation:Animals
  18. Aguirre V, Stylopoulos N, Grinbaum R, Kaplan LM. An endoluminal sleeve induces substantial weight loss and normalizes glucose homeostasis in rats with diet-induced obesity. Obesity (Silver Spring). 2008 Dec; 16(12):2585-92. PMID: 19279655.
    Citations: 29     Fields:    Translation:AnimalsCells
  19. Estépar RS, Stylopoulos N, Ellis R, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic ultrasound navigation system for transgastric access procedures. Comput Aided Surg. 2007 Nov; 12(6):311-24. PMID: 18066947.
    Citations: 9     Fields:    Translation:Humans
  20. Stylopoulos N, Vosburgh KG. Assessing technical skill in surgery and endoscopy: a set of metrics and an algorithm (C-PASS) to assess skills in surgical and endoscopic procedures. Surg Innov. 2007 Jun; 14(2):113-21. PMID: 17558017.
    Citations: 6     Fields:    Translation:Humans
  21. Vosburgh KG, Stylopoulos N, Estepar RS, Ellis RE, Samset E, Thompson CC. EUS with CT improves efficiency and structure identification over conventional EUS. Gastrointest Endosc. 2007 May; 65(6):866-70. PMID: 17466206.
    Citations: 9     Fields:    Translation:Animals
  22. San José Estépar R, Stylopoulos N, Ellis RE, Samset E, Westin CF, Thompson C, Vosburgh K. Towards scarless surgery: an endoscopic-ultrasound navigation system for transgastric access procedures. Med Image Comput Comput Assist Interv. 2006; 9(Pt 1):445-53. PMID: 17354921.
    Citations: 3     Fields:    Translation:Humans
  23. Maithel SK, Stylopoulos N, Jones DB, Rattner DW, Kaplan LM. Intact Leptin Signaling Is Required for Changes in Food Intake After Roux-en-Y Gastric Bypass in Rats. Digestive Disease Week, Chicago, IL, USA. 2005.
  24. Stylopoulos N, Davis P, Pettit JD, Rattner DW, Kaplan LM. Changes in serum ghrelin predict weight loss after Roux-en-Y gastric bypass in rats. Surg Endosc. 2005 Jul; 19(7):942-6. PMID: 15920683.
    Citations: 22     Fields:    Translation:Animals
  25. Stylopoulos N, Rattner DW. The history of hiatal hernia surgery: from Bowditch to laparoscopy. Ann Surg. 2005 Jan; 241(1):185-93. PMID: 15622007.
    Citations: 33     Fields:    Translation:Humans
  26. Maithel SK, Villegas L, Stylopoulos N, Dawson S, Jones DB. Simulated laparoscopy using a head-mounted display vs traditional video monitor: an assessment of performance and muscle fatigue. Surg Endosc. 2005 Mar; 19(3):406-11. PMID: 15624063.
    Citations: 13     Fields:    
  27. Stylopoulos N, Cotin S, Maithel SK, Ottensmeye M, Jackson PG, Bardsley RS, Neumann PF, Rattner DW, Dawson SL. Computer-enhanced laparoscopic training system (CELTS): bridging the gap. Surg Endosc. 2004 May; 18(5):782-9. PMID: 15216861.
    Citations: 12     Fields:    Translation:Humans
  28. Stylopoulos N, Rattner D. Robotics and ergonomics. Surg Clin North Am. 2003 Dec; 83(6):1321-37. PMID: 14712869.
    Citations: 13     Fields:    Translation:Humans
  29. Sims C, Stylopoulos N, Clavijo J, Barlow C. Histologic characteristics of laparoscopic saline-enhanced electrosurgery of liver and splenic injuries. Surg Endosc. 2003 Nov; 17(11):1739-43. PMID: 12739124.
    Citations:    Fields:    Translation:Animals
  30. Cotin S, Stylopoulos N, Neumann P, Ottensmeyer M, Dawson S. A software based implementation for evaluating surgical performance using kinematic analysis. 2003.
  31. Stylopoulos N, Cotin S, Dawson S, Ottensmeyer M, Neumann P, Bardsley R, Russell M, Jackson P, Rattner D. CELTS: a clinically-based Computer Enhanced Laparoscopic Training System. Stud Health Technol Inform. 2003; 94:336-42. PMID: 15455919.
    Citations: 3     Fields:    
  32. Stylopoulos N, Rattner DW. Paraesophageal hernia: when to operate? Adv Surg. 2003; 37:213-29. PMID: 12953635.
    Citations: 1     Fields:    Translation:Humans
  33. Stylopoulos N, Gazelle GS, Rattner DW. A cost--utility analysis of treatment options for inguinal hernia in 1,513,008 adult patients. Surg Endosc. 2003 Feb; 17(2):180-9. PMID: 12415334.
    Citations: 25     Fields:    Translation:Humans
  34. Stylopoulos N, Gazelle GS, Rattner DW. Paraesophageal hernias: operation or observation? Ann Surg. 2002 Oct; 236(4):492-500; discussion 500-1. PMID: 12368678.
    Citations: 80     Fields:    Translation:Humans
  35. Stylopoulos N, Bunker CJ, Rattner DW. Development of achalasia secondary to laparoscopic Nissen fundoplication. J Gastrointest Surg. 2002 May-Jun; 6(3):368-76; discussion 377-78. PMID: 12022989.
    Citations: 14     Fields:    Translation:Humans
  36. Tay BK, Stylopoulos N, De S, Rattner DW, Srinivasan MA. Measurement of in-vivo force response of intra-abdominal soft tissues for surgical simulation. Stud Health Technol Inform. 2002; 85:514-9. PMID: 15458143.
    Citations: 1     Fields:    Translation:HumansAnimals
  37. Linos DA, Stylopoulos N. How accurate is computed tomography in predicting the real size of adrenal tumors? A retrospective study. Arch Surg. 1997 Jul; 132(7):740-3. PMID: 9230858.
    Citations: 5     Fields:    Translation:Humans
  38. Linos DA, Stylopoulos N, Boukis M, Souvatzoglou A, Raptis S, Papadimitriou J. Anterior, posterior, or laparoscopic approach for the management of adrenal diseases? Am J Surg. 1997 Feb; 173(2):120-5. PMID: 9074377.
    Citations: 14     Fields:    Translation:Humans
  39. Linos DA, Stylopoulos N, Raptis SA. Adrenaloma: a call for more aggressive management. World J Surg. 1996 Sep; 20(7):788-92; discussion 792-3. PMID: 8678952.
    Citations: 10     Fields:    Translation:Humans
  40. Ferreiro JA, Stylopoulos N. Oncocytic differentiation in salivary gland tumours. J Laryngol Otol. 1995 Jun; 109(6):569-71. PMID: 7643006.
    Citations: 3     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.