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Axel Schambach, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Löfvall H, Rothe M, Schambach A, Henriksen K, Richter J, Moscatelli I. Hematopoietic Stem Cell-Targeted Neonatal Gene Therapy with a Clinically Applicable Lentiviral Vector Corrects Osteopetrosis in oc/oc Mice. Hum Gene Ther. 2019 Jul 03. PMID: 31179768.
    Citations:    
  2. Oberschmidt O, Morgan M, Huppert V, Kessler J, Gardlowski T, Matthies N, Aleksandrova K, Arseniev L, Schambach A, Koehl U, Kloess S. Development of Automated Separation, Expansion, and Quality Control Protocols for Clinical-Scale Manufacturing of Primary Human NK Cells and Alpharetroviral Chimeric Antigen Receptor Engineering. Hum Gene Ther Methods. 2019 Jun; 30(3):102-120. PMID: 30997855.
    Citations:    
  3. Kloess S, Oberschmidt O, Dahlke J, Vu XK, Neudoerfl C, Kloos A, Gardlowski T, Matthies N, Heuser M, Meyer J, Sauer M, Falk C, Koehl U, Schambach A, Morgan MA. Preclinical Assessment of Suitable Natural Killer Cell Sources for Chimeric Antigen Receptor Natural Killer-Based "Off-the-Shelf" Acute Myeloid Leukemia Immunotherapies. Hum Gene Ther. 2019 Apr; 30(4):381-401. PMID: 30734584.
    Citations:    
  4. Klapdor R, Wang S, Morgan M, Dörk T, Hacker U, Hillemanns P, Büning H, Schambach A. Characterization of a Novel Third-Generation Anti-CD24-CAR against Ovarian Cancer. Int J Mol Sci. 2019 Feb 03; 20(3). PMID: 30717444.
    Citations:    
  5. Ackermann M, Kempf H, Hetzel M, Hesse C, Hashtchin AR, Brinkert K, Schott JW, Haake K, Kühnel MP, Glage S, Figueiredo C, Jonigk D, Sewald K, Schambach A, Wronski S, Moritz T, Martin U, Zweigerdt R, Munder A, Lachmann N. Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections. Nat Commun. 2018 11 30; 9(1):5088. PMID: 30504915.
    Citations:    Fields:    Translation:HumansAnimalsCells
  6. Poletti V, Urbinati F, Charrier S, Corre G, Hollis RP, Campo Fernandez B, Martin S, Rothe M, Schambach A, Kohn DB, Mavilio F. Pre-clinical Development of a Lentiviral Vector Expressing the Anti-sickling ßAS3 Globin for Gene Therapy for Sickle Cell Disease. Mol Ther Methods Clin Dev. 2018 Dec 14; 11:167-179. PMID: 30533448.
    Citations:    
  7. Morgan MA, Schambach A. Engineering CAR-T Cells for Improved Function Against Solid Tumors. Front Immunol. 2018; 9:2493. PMID: 30420856.
    Citations:    
  8. Philipp F, Selich A, Rothe M, Hoffmann D, Rittinghausen S, Morgan MA, Klatt D, Glage S, Lienenklaus S, Neuhaus V, Sewald K, Braun A, Schambach A. Human Teratoma-Derived Hematopoiesis Is a Highly Polyclonal Process Supported by Human Umbilical Vein Endothelial Cells. Stem Cell Reports. 2018 Nov 13; 11(5):1051-1060. PMID: 30344010.
    Citations:    Fields:    
  9. Paredes R, Schneider M, Stevens A, White DJ, K Williamson AJ, Muter J, Pearson S, Kelly JR, Connors K, Wiseman DH, Chadwick JA, Löffler H, Teng HY, Lovell S, Unwin R, van de Vrugt HJ, Smith H, Kustikova O, Schambach A, P Somervaille TC, Pierce A, Whetton AD, Meyer S. Erratum: EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association. Nucleic Acids Res. 2018 09 19; 46(16):8663. PMID: 30102373.
    Citations:    Fields:    
  10. Knopp Y, Geis FK, Heckl D, Horn S, Neumann T, Kuehle J, Meyer J, Fehse B, Baum C, Morgan M, Meyer J, Schambach A, Galla M. Transient Retrovirus-Based CRISPR/Cas9 All-in-One Particles for Efficient, Targeted Gene Knockout. Mol Ther Nucleic Acids. 2018 Dec 07; 13:256-274. PMID: 30317165.
    Citations:    
  11. Paredes R, Schneider M, Stevens A, White DJ, Williamson AJK, Muter J, Pearson S, Kelly JR, Connors K, Wiseman DH, Chadwick JA, Löffler H, Teng HY, Lovell S, Unwin R, van de Vrugt HJ, Smith H, Kustikova O, Schambach A, Somervaille TCP, Pierce A, Whetton AD, Meyer S. EVI1 carboxy-terminal phosphorylation is ATM-mediated and sustains transcriptional modulation and self-renewal via enhanced CtBP1 association. Nucleic Acids Res. 2018 Sep 06; 46(15):7662-7674. PMID: 29939287.
    Citations:    Fields:    
  12. Morgan MA, Schambach A. Chimeric Antigen Receptor T Cells: Extending Translation from Liquid to Solid Tumors. Hum Gene Ther. 2018 10; 29(10):1083-1097. PMID: 30156435.
    Citations:    Fields:    
  13. Hammerschmidt SI, Werth K, Rothe M, Galla M, Permanyer M, Patzer GE, Bubke A, Frenk DN, Selich A, Lange L, Schambach A, Bošnjak B, Förster R. CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo. Front Immunol. 2018; 9:1949. PMID: 30210501.
    Citations:    
  14. Maetzig T, Morgan M, Schambach A. Fluorescent genetic barcoding for cellular multiplex analyses. Exp Hematol. 2018 11; 67:10-17. PMID: 30098396.
    Citations:    Fields:    
  15. van Diepen L, Buettner FFR, Hoffmann D, Thiesler CT, von Bohlen Und Halbach O, von Bohlen Und Halbach V, Jensen LR, Steinemann D, Edvardson S, Elpeleg O, Schambach A, Gerardy-Schahn R, Kuss AW. A patient-specific induced pluripotent stem cell model for West syndrome caused by ST3GAL3 deficiency. Eur J Hum Genet. 2018 12; 26(12):1773-1783. PMID: 30089820.
    Citations:    
  16. Salari A, Thomay K, Lentes J, Ebersold J, Hagedorn M, Skawran B, Davenport C, Schambach A, Schlegelberger B, Göhring G. Effect of TP53 contact and conformational mutations on cell survival and erythropoiesis of human hematopoietic stem cells in a long term culture model. Oncotarget. 2018 Jul 06; 9(52):29869-29876. PMID: 30042819.
    Citations:    
  17. Brendel C, Rothe M, Santilli G, Charrier S, Stein S, Kunkel H, Abriss D, Müller-Kuller U, Gaspar B, Modlich U, Galy A, Schambach A, Thrasher AJ, Grez M. Non-Clinical Efficacy and Safety Studies on G1XCGD, a Lentiviral Vector for Ex Vivo Gene Therapy of X-Linked Chronic Granulomatous Disease. Hum Gene Ther Clin Dev. 2018 06; 29(2):69-79. PMID: 29664709.
    Citations:    Fields:    
  18. Poletti V, Charrier S, Corre G, Gjata B, Vignaud A, Zhang F, Rothe M, Schambach A, Gaspar HB, Thrasher AJ, Mavilio F. Preclinical Development of a Lentiviral Vector for Gene Therapy of X-Linked Severe Combined Immunodeficiency. Mol Ther Methods Clin Dev. 2018 Jun 15; 9:257-269. PMID: 29707600.
    Citations:    
  19. Labuhn M, Adams FF, Ng M, Knoess S, Schambach A, Charpentier EM, Schwarzer A, Mateo JL, Klusmann JH, Heckl D. Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications. Nucleic Acids Res. 2018 02 16; 46(3):1375-1385. PMID: 29267886.
    Citations: 1     Fields:    
  20. Adams FF, Hoffmann T, Zuber J, Heckl D, Schambach A, Schwarzer A. Pooled Generation of Lentiviral Tetracycline-Regulated microRNA Embedded Short Hairpin RNA Libraries. Hum Gene Ther Methods. 2018 02; 29(1):16-29. PMID: 29325442.
    Citations:    Fields:    Translation:HumansCells
  21. Ghosh S, Carmo M, Calero-Garcia M, Ricciardelli I, Bustamante Ogando JC, Blundell MP, Schambach A, Ashton-Rickardt PG, Booth C, Ehl S, Lehmberg K, Thrasher AJ, Gaspar HB. T-cell gene therapy for perforin deficiency corrects cytotoxicity defects and prevents hemophagocytic lymphohistiocytosis manifestations. J Allergy Clin Immunol. 2018 Sep; 142(3):904-913.e3. PMID: 29355678.
    Citations: 1     Fields:    
  22. Neehus AL, Lam J, Haake K, Merkert S, Schmidt N, Mucci A, Ackermann M, Schubert M, Happle C, Kühnel MP, Blank P, Philipp F, Goethe R, Jonigk D, Martin U, Kalinke U, Baumann U, Schambach A, Roesler J, Lachmann N. Impaired IFN?-Signaling and Mycobacterial Clearance in IFN?R1-Deficient Human iPSC-Derived Macrophages. Stem Cell Reports. 2018 01 09; 10(1):7-16. PMID: 29249666.
    Citations:    Fields:    Translation:HumansCells
  23. Hetzel M, Mucci A, Blank P, Nguyen AHH, Schiller J, Halle O, Kühnel MP, Billig S, Meineke R, Brand D, Herder V, Baumgärtner W, Bange FC, Goethe R, Jonigk D, Förster R, Gentner B, Casanova JL, Bustamante J, Schambach A, Kalinke U, Lachmann N. Hematopoietic stem cell gene therapy for IFN?R1 deficiency protects mice from mycobacterial infections. Blood. 2018 02 01; 131(5):533-545. PMID: 29233822.
    Citations: 1     Fields:    Translation:AnimalsCells
  24. Schambach A, Schott JW, Morgan MA. Uncoupling the Oncogenic Engine. Cancer Res. 2017 11 15; 77(22):6060-6064. PMID: 29097608.
    Citations:    Fields:    Translation:HumansCells
  25. Geis FK, Galla M, Hoffmann D, Kuehle J, Zychlinski D, Maetzig T, Schott JW, Schwarzer A, Goffinet C, Goff SP, Schambach A. Correction to: Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells. Retrovirology. 2017 10 18; 14(1):48. PMID: 29047401.
    Citations:    Fields:    
  26. Biasco L, Rothe M, Büning H, Schambach A. Analyzing the Genotoxicity of Retroviral Vectors in Hematopoietic Cell Gene Therapy. Mol Ther Methods Clin Dev. 2018 Mar 16; 8:21-30. PMID: 29159200.
    Citations: 1     
  27. Moscatelli I, Löfvall H, Schneider Thudium C, Rothe M, Montano C, Kertész Z, Sirin M, Schulz A, Schambach A, Henriksen K, Richter J. Targeting NSG Mice Engrafting Cells with a Clinically Applicable Lentiviral Vector Corrects Osteoclasts in Infantile Malignant Osteopetrosis. Hum Gene Ther. 2018 08; 29(8):938-949. PMID: 28726516.
    Citations:    Fields:    
  28. Biasco L, Rothe M, Schott JW, Schambach A. Integrating Vectors for Gene Therapy and Clonal Tracking of Engineered Hematopoiesis. Hematol Oncol Clin North Am. 2017 10; 31(5):737-752. PMID: 28895844.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  29. Peking P, Koller U, Duarte B, Murillas R, Wolf S, Maetzig T, Rothe M, Kocher T, García M, Brachtl G, Schambach A, Larcher F, Reichelt J, Bauer JW, Murauer EM. An RNA-targeted therapy for dystrophic epidermolysis bullosa. Nucleic Acids Res. 2017 Sep 29; 45(17):10259-10269. PMID: 28973459.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  30. Hetzel M, Suzuki T, Hashtchin AR, Arumugam P, Carey B, Schwabbauer M, Kuhn A, Meyer J, Schambach A, Van Der Loo J, Moritz T, Trapnell BC, Lachmann N. Function and Safety of Lentivirus-Mediated Gene Transfer for CSF2RA-Deficiency. Hum Gene Ther Methods. 2017 12; 28(6):318-329. PMID: 28854814.
    Citations:    Fields:    Translation:HumansAnimalsCells
  31. Klapdor R, Wang S, Hacker U, Büning H, Morgan M, Dörk T, Hillemanns P, Schambach A. Improved Killing of Ovarian Cancer Stem Cells by Combining a Novel Chimeric Antigen Receptor-Based Immunotherapy and Chemotherapy. Hum Gene Ther. 2017 10; 28(10):886-896. PMID: 28836469.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  32. Klöß S, Oberschmidt O, Morgan M, Dahlke J, Arseniev L, Huppert V, Granzin M, Gardlowski T, Matthies N, Soltenborn S, Schambach A, Koehl U. Optimization of Human NK Cell Manufacturing: Fully Automated Separation, Improved Ex Vivo Expansion Using IL-21 with Autologous Feeder Cells, and Generation of Anti-CD123-CAR-Expressing Effector Cells. Hum Gene Ther. 2017 10; 28(10):897-913. PMID: 28810809.
    Citations: 4     Fields:    Translation:HumansCells
  33. Kunkiel J, Gödecke N, Ackermann M, Hoffmann D, Schambach A, Lachmann N, Wirth D, Moritz T. The CpG-sites of the CBX3 ubiquitous chromatin opening element are critical structural determinants for the anti-silencing function. Sci Rep. 2017 08 11; 7(1):7919. PMID: 28801671.
    Citations:    Fields:    
  34. Schwarzer A, Emmrich S, Schmidt F, Beck D, Ng M, Reimer C, Adams FF, Grasedieck S, Witte D, Käbler S, Wong JWH, Shah A, Huang Y, Jammal R, Maroz A, Jongen-Lavrencic M, Schambach A, Kuchenbauer F, Pimanda JE, Reinhardt D, Heckl D, Klusmann JH. The non-coding RNA landscape of human hematopoiesis and leukemia. Nat Commun. 2017 08 09; 8(1):218. PMID: 28794406.
    Citations: 8     Fields:    Translation:HumansCells
  35. Stahlhut M, Schambach A, Kustikova OS. Multimodal Lentiviral Vectors for Pharmacologically Controlled Switching Between Constitutive Single Gene Expression and Tetracycline-Regulated Multiple Gene Collaboration. Hum Gene Ther Methods. 2017 08; 28(4):191-204. PMID: 28683573.
    Citations:    Fields:    Translation:AnimalsCells
  36. Pittermann E, Lachmann N, MacLean G, Emmrich S, Ackermann M, Göhring G, Schlegelberger B, Welte K, Schambach A, Heckl D, Orkin SH, Cantz T, Klusmann JH. Gene correction of HAX1 reversed Kostmann disease phenotype in patient-specific induced pluripotent stem cells. Blood Adv. 2017 Jun 13; 1(14):903-914. PMID: 29296734.
    Citations:    
  37. Geis FK, Galla M, Hoffmann D, Kuehle J, Zychlinski D, Maetzig T, Schott JW, Schwarzer A, Goffinet C, Goff SP, Schambach A. Potent and reversible lentiviral vector restriction in murine induced pluripotent stem cells. Retrovirology. 2017 05 31; 14(1):34. PMID: 28569216.
    Citations: 2     Fields:    Translation:AnimalsCells
  38. Vink CA, Counsell JR, Perocheau DP, Karda R, Buckley SMK, Brugman MH, Galla M, Schambach A, McKay TR, Waddington SN, Howe SJ. Eliminating HIV-1 Packaging Sequences from Lentiviral Vector Proviruses Enhances Safety and Expedites Gene Transfer for Gene Therapy. Mol Ther. 2017 08 02; 25(8):1790-1804. PMID: 28550974.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  39. Adams FF, Heckl D, Hoffmann T, Talbot SR, Kloos A, Thol F, Heuser M, Zuber J, Schambach A, Schwarzer A. An optimized lentiviral vector system for conditional RNAi and efficient cloning of microRNA embedded short hairpin RNA libraries. Biomaterials. 2017 Sep; 139:102-115. PMID: 28599149.
    Citations: 1     Fields:    Translation:HumansCells
  40. Huang J, Khan A, Au BC, Barber DL, López-Vásquez L, Prokopishyn NL, Boutin M, Rothe M, Rip JW, Abaoui M, Nagree MS, Dworski S, Schambach A, Keating A, West ML, Klassen J, Turner PV, Sirrs S, Rupar CA, Auray-Blais C, Foley R, Medin JA. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34+ Cells for Correction of Fabry Disease. Mol Ther Methods Clin Dev. 2017 Jun 16; 5:241-258. PMID: 28603745.
    Citations: 3     
  41. Debnath S, Jaako P, Siva K, Rothe M, Chen J, Dahl M, Gaspar HB, Flygare J, Schambach A, Karlsson S. Lentiviral Vectors with Cellular Promoters Correct Anemia and Lethal Bone Marrow Failure in a Mouse Model for Diamond-Blackfan Anemia. Mol Ther. 2017 08 02; 25(8):1805-1814. PMID: 28434866.
    Citations:    Fields:    Translation:HumansAnimalsCells
  42. Westhaus S, Deest M, Nguyen ATX, Stanke F, Heckl D, Costa R, Schambach A, Manns MP, Berg T, Vondran FWR, Sarrazin C, Ciesek S, von Hahn T. Scavenger receptor class B member 1 (SCARB1) variants modulate hepatitis C virus replication cycle and viral load. J Hepatol. 2017 08; 67(2):237-245. PMID: 28363797.
    Citations: 1     Fields:    Translation:HumansCells
  43. Pfaff N, Liebhaber S, Möbus S, Beh-Pajooh A, Fiedler J, Pfanne A, Schambach A, Thum T, Cantz T, Moritz T. Inhibition of miRNA-212/132 improves the reprogramming of fibroblasts into induced pluripotent stem cells by de-repressing important epigenetic remodelling factors. Stem Cell Res. 2017 04; 20:70-75. PMID: 28314201.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  44. Montano Almendras CP, Thudium CS, Löfvall H, Moscatelli I, Schambach A, Henriksen K, Richter J. Forced expression of human macrophage colony-stimulating factor in CD34+ cells promotes monocyte differentiation in vitro and in vivo but blunts osteoclastogenesis in vitro. Eur J Haematol. 2017 May; 98(5):517-526. PMID: 28160330.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  45. Ehrlich M, Mozafari S, Glatza M, Starost L, Velychko S, Hallmann AL, Cui QL, Schambach A, Kim KP, Bachelin C, Marteyn A, Hargus G, Johnson RM, Antel J, Sterneckert J, Zaehres H, Schöler HR, Baron-Van Evercooren A, Kuhlmann T. Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors. Proc Natl Acad Sci U S A. 2017 03 14; 114(11):E2243-E2252. PMID: 28246330.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  46. Endele M, Loeffler D, Kokkaliaris KD, Hilsenbeck O, Skylaki S, Hoppe PS, Schambach A, Stanley ER, Schroeder T. CSF-1-induced Src signaling can instruct monocytic lineage choice. Blood. 2017 03 23; 129(12):1691-1701. PMID: 28159742.
    Citations:    Fields:    Translation:AnimalsCells
  47. Maetzig T, Ruschmann J, Lai CK, Ngom M, Imren S, Rosten P, Norddahl GL, von Krosigk N, Sanchez Milde L, May C, Selich A, Rothe M, Dhillon I, Schambach A, Humphries RK. A Lentiviral Fluorescent Genetic Barcoding System for Flow Cytometry-Based Multiplex Tracking. Mol Ther. 2017 03 01; 25(3):606-620. PMID: 28253481.
    Citations: 4     Fields:    Translation:HumansCells
  48. Müller LU, Milsom MD, Kim MO, Schambach A, Schuesler T, Williams DA. Rapid Lentiviral Transduction Preserves the Engraftment Potential of Fanca-/- Hematopoietic Stem Cells. Mol Ther. 2008 Jun; 16(6):1154-1160. PMID: 28178472.
    Citations:    Fields:    
  49. Huang J, Liu Y, Au BC, Barber DL, Arruda A, Schambach A, Rothe M, Minden MD, Paige CJ, Medin JA. Preclinical validation: LV/IL-12 transduction of patient leukemia cells for immunotherapy of AML. Mol Ther Methods Clin Dev. 2016; 3:16074. PMID: 27933304.
    Citations: 2     
  50. Metcalf JA, Ma X, Linders B, Wu S, Schambach A, Ohlemiller KK, Kovacs A, Bigg M, He L, Tollefsen DM, Ponder KP. A Self-inactivating ?-Retroviral Vector Reduces Manifestations of Mucopolysaccharidosis I in Mice. Mol Ther. 2010 Feb; 18(2):334-342. PMID: 28182939.
    Citations:    
  51. Eggenschwiler R, Moslem M, Fráguas MS, Galla M, Papp O, Naujock M, Fonfara I, Gensch I, Wähner A, Beh-Pajooh A, Mussolino C, Tauscher M, Steinemann D, Wegner F, Petri S, Schambach A, Charpentier E, Cathomen T, Cantz T. Improved bi-allelic modification of a transcriptionally silent locus in patient-derived iPSC by Cas9 nickase. Sci Rep. 2016 12 02; 6:38198. PMID: 27910942.
    Citations: 4     Fields:    Translation:HumansCells
  52. Punwani D, Kawahara M, Yu J, Sanford U, Roy S, Patel K, Carbonaro DA, Karlen AD, Khan S, Cornetta K, Rothe M, Schambach A, Kohn DB, Malech HL, McIvor RS, Puck JM, Cowan MJ. Lentivirus Mediated Correction of Artemis-Deficient Severe Combined Immunodeficiency. Hum Gene Ther. 2017 01; 28(1):112-124. PMID: 27611239.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  53. Mucci A, Kunkiel J, Suzuki T, Brennig S, Glage S, Kühnel MP, Ackermann M, Happle C, Kuhn A, Schambach A, Trapnell BC, Hansen G, Moritz T, Lachmann N. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency. Stem Cell Reports. 2016 08 09; 7(2):292-305. PMID: 27453007.
    Citations: 6     Fields:    Translation:AnimalsCells
  54. Schott JW, Morgan M, Galla M, Schambach A. Viral and Synthetic RNA Vector Technologies and Applications. Mol Ther. 2016 09; 24(9):1513-27. PMID: 27377044.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  55. Börger AK, Eicke D, Wolf C, Gras C, Aufderbeck S, Schulze K, Engels L, Eiz-Vesper B, Schambach A, Guzman CA, Lachmann N, Moritz T, Martin U, Blasczyk R, Figueiredo C. Generation of HLA-Universal iPSC-Derived Megakaryocytes and Platelets for Survival Under Refractoriness Conditions. Mol Med. 2016 Sep; 22:274-285. PMID: 27262025.
    Citations: 6     Fields:    
  56. Hübner J, Hoseini SS, Suerth JD, Hoffmann D, Maluski M, Herbst J, Maul H, Ghosh A, Eiz-Vesper B, Yuan Q, Ott M, Heuser M, Schambach A, Sauer MG. Generation of Genetically Engineered Precursor T-Cells From Human Umbilical Cord Blood Using an Optimized Alpharetroviral Vector Platform. Mol Ther. 2016 08; 24(7):1216-26. PMID: 27138041.
    Citations: 1     Fields:    Translation:HumansCells
  57. Garcia-Gomez M, Calabria A, Garcia-Bravo M, Benedicenti F, Kosinski P, López-Manzaneda S, Hill C, Del Mar Mañu-Pereira M, Martín MA, Orman I, Vives-Corrons JL, Kung C, Schambach A, Jin S, Bueren JA, Montini E, Navarro S, Segovia JC. Safe and Efficient Gene Therapy for Pyruvate Kinase Deficiency. Mol Ther. 2016 08; 24(7):1187-98. PMID: 27138040.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  58. Labenski V, Suerth JD, Barczak E, Heckl D, Levy C, Bernadin O, Charpentier E, Williams DA, Fehse B, Verhoeyen E, Schambach A. Alpharetroviral self-inactivating vectors produced by a superinfection-resistant stable packaging cell line allow genetic modification of primary human T lymphocytes. Biomaterials. 2016 08; 97:97-109. PMID: 27162078.
    Citations: 2     Fields:    Translation:HumansCells
  59. Salari A, Thomay K, Himmler K, Vajen B, Schienke A, Hagedorn M, Ebersold J, Kreipe HH, Krüger A, Schambach A, Schlegelberger B, Göhring G. Establishing a murine xenograft-model for long-term analysis of factors inducing chromosomal instability in myelodysplastic syndrome: Pitfalls and successes. Cancer Genet. 2016 06; 209(6):258-66. PMID: 27184732.
    Citations: 1     Fields:    Translation:HumansAnimals
  60. Manukjan G, Ripperger T, Venturini L, Stadler M, Göhring G, Schambach A, Schlegelberger B, Steinemann D. GABP is necessary for stem/progenitor cell maintenance and myeloid differentiation in human hematopoiesis and chronic myeloid leukemia. Stem Cell Res. 2016 05; 16(3):677-81. PMID: 27100840.
    Citations:    Fields:    Translation:HumansCells
  61. Selich A, Daudert J, Hass R, Philipp F, von Kaisenberg C, Paul G, Cornils K, Fehse B, Rittinghausen S, Schambach A, Rothe M. Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology. Stem Cells Transl Med. 2016 May; 5(5):591-601. PMID: 27034413.
    Citations: 5     Fields:    Translation:HumansCells
  62. Song G, Pacher M, Balakrishnan A, Yuan Q, Tsay HC, Yang D, Reetz J, Brandes S, Dai Z, Pützer BM, Araúzo-Bravo MJ, Steinemann D, Luedde T, Schwabe RF, Manns MP, Schöler HR, Schambach A, Cantz T, Ott M, Sharma AD. Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis. Cell Stem Cell. 2016 06 02; 18(6):797-808. PMID: 26923201.
    Citations: 27     Fields:    Translation:AnimalsCells
  63. Karpinski J, Hauber I, Chemnitz J, Schäfer C, Paszkowski-Rogacz M, Chakraborty D, Beschorner N, Hofmann-Sieber H, Lange UC, Grundhoff A, Hackmann K, Schrock E, Abi-Ghanem J, Pisabarro MT, Surendranath V, Schambach A, Lindner C, van Lunzen J, Hauber J, Buchholz F. Directed evolution of a recombinase that excises the provirus of most HIV-1 primary isolates with high specificity. Nat Biotechnol. 2016 Apr; 34(4):401-9. PMID: 26900663.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  64. Viereck J, Kumarswamy R, Foinquinos A, Xiao K, Avramopoulos P, Kunz M, Dittrich M, Maetzig T, Zimmer K, Remke J, Just A, Fendrich J, Scherf K, Bolesani E, Schambach A, Weidemann F, Zweigerdt R, de Windt LJ, Engelhardt S, Dandekar T, Batkai S, Thum T. Long noncoding RNA Chast promotes cardiac remodeling. Sci Transl Med. 2016 Feb 17; 8(326):326ra22. PMID: 26888430.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  65. Papapetrou EP, Schambach A. Gene Insertion Into Genomic Safe Harbors for Human Gene Therapy. Mol Ther. 2016 Apr; 24(4):678-84. PMID: 26867951.
    Citations: 10     Fields:    Translation:Humans
  66. Abbey M, Hakim C, Anand R, Lafera J, Schambach A, Kispert A, Taft MH, Kaever V, Kotlyarov A, Gaestel M, Menon MB. GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis. Sci Rep. 2016 Jan 28; 6:20007. PMID: 26818767.
    Citations: 4     Fields:    Translation:AnimalsCells
  67. Thiesler CT, Cajic S, Hoffmann D, Thiel C, van Diepen L, Hennig R, Sgodda M, Weißmann R, Reichl U, Steinemann D, Diekmann U, Huber NM, Oberbeck A, Cantz T, Kuss AW, Körner C, Schambach A, Rapp E, Buettner FF. Glycomic Characterization of Induced Pluripotent Stem Cells Derived from a Patient Suffering from Phosphomannomutase 2 Congenital Disorder of Glycosylation (PMM2-CDG). Mol Cell Proteomics. 2016 Apr; 15(4):1435-52. PMID: 26785728.
    Citations: 6     Fields:    Translation:HumansCells
  68. Maetzig T, Schambach A. Development of Inducible Molecular Switches Based on All-in-One Lentiviral Vectors Equipped with Drug Controlled FLP Recombinase. Methods Mol Biol. 2016; 1448:23-39. PMID: 27317170.
    Citations:    Fields:    Translation:HumansAnimalsCells
  69. Stahlhut M, Schambach A, Kustikova OS. Transduction of Murine Hematopoietic Stem Cells with Tetracycline-regulated Lentiviral Vectors. Methods Mol Biol. 2016; 1448:65-76. PMID: 27317173.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  70. Stahlhut M, Ha TC, Morgan M, Schambach A, Kustikova OS. Comparison of Tetracycline-regulated Promoters in Lentiviral-based Vectors in Murine Transplantation Studies. Curr Gene Ther. 2016; 16(4):242-248. PMID: 27739375.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  71. Schambach A, Morgan M. Retroviral Vectors for Cancer Gene Therapy. Recent Results Cancer Res. 2016; 209:17-35. PMID: 28101685.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  72. Brennig S, Lachmann N, Buchegger T, Hetzel M, Schambach A, Moritz T. Chemoprotection of murine hematopoietic cells by combined gene transfer of cytidine deaminase (CDD) and multidrug resistance 1 gene (MDR1). J Exp Clin Cancer Res. 2015 Dec 12; 34:148. PMID: 26651614.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  73. Regelin M, Blume J, Pommerencke J, Vakilzadeh R, Witzlau K, Lyszkiewicz M, Zietara N, Saran N, Schambach A, Krueger A. Responsiveness of Developing T Cells to IL-7 Signals Is Sustained by miR-17~92. J Immunol. 2015 Nov 15; 195(10):4832-40. PMID: 26475928.
    Citations: 3     Fields:    Translation:AnimalsCells
  74. Hoffmann D, Göhring G, Heuser M, Ganser A, Schambach A, Morgan MA. Letter to the Editor: Production of Mature Healthy Hematopoietic Cells from Induced Pluripotent Stem Cells Derived from an AML Diagnostic Sample Containing the t(8;21) Translocation. Stem Cells. 2016 Mar; 34(3):797-9. PMID: 26388310.
    Citations:    Fields:    Translation:HumansCells
  75. Schott JW, Hoffmann D, Schambach A. Retrovirus-based vectors for transient and permanent cell modification. Curr Opin Pharmacol. 2015 Oct; 24:135-46. PMID: 26433198.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  76. Suerth JD, Morgan MA, Kloess S, Heckl D, Neudörfl C, Falk CS, Koehl U, Schambach A. Efficient generation of gene-modified human natural killer cells via alpharetroviral vectors. J Mol Med (Berl). 2016 Jan; 94(1):83-93. PMID: 26300042.
    Citations: 8     Fields:    Translation:HumansCells
  77. Dreyer AK, Hoffmann D, Lachmann N, Ackermann M, Steinemann D, Timm B, Siler U, Reichenbach J, Grez M, Moritz T, Schambach A, Cathomen T. TALEN-mediated functional correction of X-linked chronic granulomatous disease in patient-derived induced pluripotent stem cells. Biomaterials. 2015 Nov; 69:191-200. PMID: 26295532.
    Citations: 12     Fields:    Translation:HumansCells
  78. Ripperger T, Manukjan G, Meyer J, Wolter S, Schambach A, Bohne J, Modlich U, Li Z, Skawran B, Schlegelberger B, Steinemann D. The heteromeric transcription factor GABP activates the ITGAM/CD11b promoter and induces myeloid differentiation. Biochim Biophys Acta. 2015 Sep; 1849(9):1145-54. PMID: 26170143.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  79. Heinz N, Ehrnström B, Schambach A, Schwarzer A, Modlich U, Schiedlmeier B. Comparison of Different Cytokine Conditions Reveals Resveratrol as a New Molecule for Ex Vivo Cultivation of Cord Blood-Derived Hematopoietic Stem Cells. Stem Cells Transl Med. 2015 Sep; 4(9):1064-72. PMID: 26160960.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  80. Rissone A, Weinacht KG, la Marca G, Bishop K, Giocaliere E, Jagadeesh J, Felgentreff K, Dobbs K, Al-Herz W, Jones M, Chandrasekharappa S, Kirby M, Wincovitch S, Simon KL, Itan Y, DeVine A, Schlaeger T, Schambach A, Sood R, Notarangelo LD, Candotti F. Reticular dysgenesis-associated AK2 protects hematopoietic stem and progenitor cell development from oxidative stress. J Exp Med. 2015 Jul 27; 212(8):1185-202. PMID: 26150473.
    Citations: 8     Fields:    Translation:AnimalsCells
  81. Dobbs K, Domínguez Conde C, Zhang SY, Parolini S, Audry M, Chou J, Haapaniemi E, Keles S, Bilic I, Okada S, Massaad MJ, Rounioja S, Alwahadneh AM, Serwas NK, Capuder K, Çiftçi E, Felgentreff K, Ohsumi TK, Pedergnana V, Boisson B, Haskologlu S, Ensari A, Schuster M, Moretta A, Itan Y, Patrizi O, Rozenberg F, Lebon P, Saarela J, Knip M, Petrovski S, Goldstein DB, Parrott RE, Savas B, Schambach A, Tabellini G, Bock C, Chatila TA, Comeau AM, Geha RS, Abel L, Buckley RH, Ikinciogullari A, Al-Herz W, Helminen M, Dogu F, Casanova JL, Boztug K, Notarangelo LD. Inherited DOCK2 Deficiency in Patients with Early-Onset Invasive Infections. N Engl J Med. 2015 Jun 18; 372(25):2409-22. PMID: 26083206.
    Citations: 26     Fields:    Translation:HumansCells
  82. Uhlig KM, Schülke S, Scheuplein VA, Malczyk AH, Reusch J, Kugelmann S, Muth A, Koch V, Hutzler S, Bodmer BS, Schambach A, Buchholz CJ, Waibler Z, Scheurer S, Mühlebach MD. Lentiviral Protein Transfer Vectors Are an Efficient Vaccine Platform and Induce a Strong Antigen-Specific Cytotoxic T Cell Response. J Virol. 2015 Sep; 89(17):9044-60. PMID: 26085166.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  83. Stahlhut M, Schwarzer A, Eder M, Yang M, Li Z, Morgan M, Schambach A, Kustikova OS. Lentiviral vector system for coordinated constitutive and drug controlled tetracycline-regulated gene co-expression. Biomaterials. 2015 Sep; 63:189-201. PMID: 26113075.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  84. Manukjan G, Ripperger T, Santer L, von Neuhoff N, Ganser A, Schambach A, Schlegelberger B, Steinemann D. Expression of the ETS transcription factor GABPa is positively correlated to the BCR-ABL1/ABL1 ratio in CML patients and affects imatinib sensitivity in vitro. Exp Hematol. 2015 Oct; 43(10):880-90. PMID: 26072332.
    Citations: 1     Fields:    Translation:HumansCells
  85. Rahman SH, Kuehle J, Reimann C, Mlambo T, Alzubi J, Maeder ML, Riedel H, Fisch P, Cantz T, Rudolph C, Mussolino C, Joung JK, Schambach A, Cathomen T. Rescue of DNA-PK Signaling and T-Cell Differentiation by Targeted Genome Editing in a prkdc Deficient iPSC Disease Model. PLoS Genet. 2015 May; 11(5):e1005239. PMID: 26000857.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  86. Zhang H, Goudeva L, Immenschuh S, Schambach A, Skokowa J, Eiz-Vesper B, Blasczyk R, Figueiredo C. miR-155 is associated with the leukemogenic potential of the class IV granulocyte colony-stimulating factor receptor in CD34? progenitor cells. Mol Med. 2015 Apr 09; 20:736-46. PMID: 25730818.
    Citations: 4     Fields:    Translation:HumansCells
  87. Schott JW, Jaeschke NM, Hoffmann D, Maetzig T, Ballmaier M, Godinho T, Cathomen T, Schambach A. Deciphering the impact of parameters influencing transgene expression kinetics after repeated cell transduction with integration-deficient retroviral vectors. Cytometry A. 2015 May; 87(5):405-18. PMID: 25728583.
    Citations: 1     Fields:    Translation:HumansCells
  88. Glienke W, Esser R, Priesner C, Suerth JD, Schambach A, Wels WS, Grez M, Kloess S, Arseniev L, Koehl U. Advantages and applications of CAR-expressing natural killer cells. Front Pharmacol. 2015; 6:21. PMID: 25729364.
    Citations: 51     
  89. Lachmann N, Ackermann M, Frenzel E, Liebhaber S, Brennig S, Happle C, Hoffmann D, Klimenkova O, Lüttge D, Buchegger T, Kühnel MP, Schambach A, Janciauskiene S, Figueiredo C, Hansen G, Skokowa J, Moritz T. Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies. Stem Cell Reports. 2015 Feb 10; 4(2):282-96. PMID: 25680479.
    Citations: 20     Fields:    Translation:HumansCells
  90. Dahl M, Doyle A, Olsson K, Månsson JE, Marques ARA, Mirzaian M, Aerts JM, Ehinger M, Rothe M, Modlich U, Schambach A, Karlsson S. Lentiviral gene therapy using cellular promoters cures type 1 Gaucher disease in mice. Mol Ther. 2015 May; 23(5):835-844. PMID: 25655314.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  91. Müller-Kuller U, Ackermann M, Kolodziej S, Brendel C, Fritsch J, Lachmann N, Kunkel H, Lausen J, Schambach A, Moritz T, Grez M. A minimal ubiquitous chromatin opening element (UCOE) effectively prevents silencing of juxtaposed heterologous promoters by epigenetic remodeling in multipotent and pluripotent stem cells. Nucleic Acids Res. 2015 Feb 18; 43(3):1577-92. PMID: 25605798.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  92. Coci EG, Maetzig T, Zychlinski D, Rothe M, Suerth JD, Klein C, Schambach A. Novel self-inactivating vectors for reconstitution of Wiskott-Aldrich syndrome. Curr Gene Ther. 2015; 15(3):245-54. PMID: 25619887.
    Citations: 3     Fields:    
  93. Carmo M, Risma KA, Arumugam P, Tiwari S, Hontz AE, Montiel-Equihua CA, Alonso-Ferrero ME, Blundell MP, Schambach A, Baum C, Malik P, Thrasher AJ, Jordan MB, Gaspar HB. Perforin gene transfer into hematopoietic stem cells improves immune dysregulation in murine models of perforin deficiency. Mol Ther. 2015 Apr; 23(4):737-45. PMID: 25523759.
    Citations: 6     Fields:    Translation:AnimalsCells
  94. Suerth JD, Labenski V, Schambach A. Alpharetroviral vectors: from a cancer-causing agent to a useful tool for human gene therapy. Viruses. 2014 Dec 05; 6(12):4811-38. PMID: 25490763.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  95. Lyszkiewicz M, Zietara N, Föhse L, Puchalka J, Diestelhorst J, Witzlau K, Prinz I, Schambach A, Krueger A. Limited niche availability suppresses murine intrathymic dendritic-cell development from noncommitted progenitors. Blood. 2015 Jan 15; 125(3):457-64. PMID: 25411428.
    Citations: 5     Fields:    Translation:AnimalsCells
  96. Coci EG, Thau-Habermann N, Maetzig T, Li Z, Klein C, Petri S, Schambach A. TEMPORARY REMOVAL: Assessment of hematopoietic and neurologic pathophysiology of HCLS1-associated protein X-1 deficiency in a Hax1-knockout mouse model. Exp Hematol. 2014 Oct 28. PMID: 25448489.
    Citations:    Fields:    
  97. Hacein-Bey-Abina S, Pai SY, Gaspar HB, Armant M, Berry CC, Blanche S, Bleesing J, Blondeau J, de Boer H, Buckland KF, Caccavelli L, Cros G, De Oliveira S, Fernández KS, Guo D, Harris CE, Hopkins G, Lehmann LE, Lim A, London WB, van der Loo JC, Malani N, Male F, Malik P, Marinovic MA, McNicol AM, Moshous D, Neven B, Oleastro M, Picard C, Ritz J, Rivat C, Schambach A, Shaw KL, Sherman EA, Silberstein LE, Six E, Touzot F, Tsytsykova A, Xu-Bayford J, Baum C, Bushman FD, Fischer A, Kohn DB, Filipovich AH, Notarangelo LD, Cavazzana M, Williams DA, Thrasher AJ. A modified ?-retrovirus vector for X-linked severe combined immunodeficiency. N Engl J Med. 2014 Oct 09; 371(15):1407-17. PMID: 25295500.
    Citations: 65     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  98. Liu L, Xu Y, He M, Zhang M, Cui F, Lu L, Yao M, Tian W, Benda C, Zhuang Q, Huang Z, Li W, Li X, Zhao P, Fan W, Luo Z, Li Y, Wu Y, Hutchins AP, Wang D, Tse HF, Schambach A, Frampton J, Qin B, Bao X, Yao H, Zhang B, Sun H, Pei D, Wang H, Wang J, Esteban MA. Transcriptional pause release is a rate-limiting step for somatic cell reprogramming. Cell Stem Cell. 2014 Nov 06; 15(5):574-88. PMID: 25312495.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  99. Haemmerle R, Phaltane R, Rothe M, Schröder S, Schambach A, Moritz T, Modlich U. Clonal Dominance With Retroviral Vector Insertions Near the ANGPT1 and ANGPT2 Genes in a Human Xenotransplant Mouse Model. Mol Ther Nucleic Acids. 2014 Oct 07; 3:e200. PMID: 25291142.
    Citations: 5     
  100. Jaako P, Debnath S, Olsson K, Modlich U, Rothe M, Schambach A, Flygare J, Karlsson S. Gene therapy cures the anemia and lethal bone marrow failure in a mouse model of RPS19-deficient Diamond-Blackfan anemia. Haematologica. 2014 Dec; 99(12):1792-8. PMID: 25216681.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  101. Wang J, Sun Q, Morita Y, Jiang H, Groß A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wüstefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL. A Differentiation Checkpoint Limits Hematopoietic Stem Cell Self-Renewal in Response to DNA Damage. Cell. 2014 Sep 11; 158(6):1444. PMID: 28915370.
    Citations: 1     Fields:    
  102. Menon MB, Sawada A, Chaturvedi A, Mishra P, Schuster-Gossler K, Galla M, Schambach A, Gossler A, Förster R, Heuser M, Kotlyarov A, Kinoshita M, Gaestel M. Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet. 2014 Aug; 10(8):e1004558. PMID: 25122120.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  103. Schambach A. Toward a safer integration profile of MLV-based retroviral vectors. Mol Ther. 2014 Aug; 22(8):1405-1406. PMID: 25082089.
    Citations: 1     Fields:    
  104. Warlich E, Schambach A, Lock D, Wedekind D, Glage S, Eckardt D, Bosio A, Knöbel S. FAS-based cell depletion facilitates the selective isolation of mouse induced pluripotent stem cells. PLoS One. 2014; 9(7):e102171. PMID: 25029550.
    Citations:    Fields:    Translation:HumansAnimalsCells
  105. Huang J, Guo X, Fan N, Song J, Zhao B, Ouyang Z, Liu Z, Zhao Y, Yan Q, Yi X, Schambach A, Frampton J, Esteban MA, Yang D, Yang H, Lai L. RAG1/2 knockout pigs with severe combined immunodeficiency. J Immunol. 2014 Aug 01; 193(3):1496-503. PMID: 24973446.
    Citations: 26     Fields:    Translation:AnimalsCells
  106. Pike-Overzet K, Baum C, Bredius RG, Cavazzana M, Driessen GJ, Fibbe WE, Gaspar HB, Hoeben RC, Lagresle-Peyrou C, Lankester A, Meij P, Schambach A, Thrasher A, Van Dongen JJ, Zwaginga JJ, Staal FJ. Successful RAG1-SCID gene therapy depends on the level of RAG1 expression. J Allergy Clin Immunol. 2014 Jul; 134(1):242-3. PMID: 25117803.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  107. Limbourg A, Schnabel S, Lozanovski VJ, Napp LC, Ha TC, Maetzig T, Bauersachs J, Naim HY, Schambach A, Limbourg FP. Genetic reporter analysis reveals an expandable reservoir of OCT4+ cells in adult skin. Cell Regen (Lond). 2014; 3(1):9. PMID: 25408888.
    Citations:    
  108. Turan S, Qiao J, Madden S, Benham C, Kotz M, Schambach A, Bode J. Expanding Flp-RMCE options: the potential of Recombinase Mediated Twin-Site Targeting (RMTT). Gene. 2014 Aug 10; 546(2):135-44. PMID: 24905650.
    Citations: 3     Fields:    Translation:AnimalsCells
  109. Felgentreff K, Du L, Weinacht KG, Dobbs K, Bartish M, Giliani S, Schlaeger T, DeVine A, Schambach A, Woodbine LJ, Davies G, Baxi SN, van der Burg M, Bleesing J, Gennery A, Manis J, Pan-Hammarström Q, Notarangelo LD. Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells. Proc Natl Acad Sci U S A. 2014 Jun 17; 111(24):8889-94. PMID: 24889605.
    Citations: 12     Fields:    Translation:HumansCells
  110. Moiani A, Suerth JD, Gandolfi F, Rizzi E, Severgnini M, De Bellis G, Schambach A, Mavilio F. Genome-wide analysis of alpharetroviral integration in human hematopoietic stem/progenitor cells. Genes (Basel). 2014 May 16; 5(2):415-29. PMID: 24840152.
    Citations: 5     
  111. Emmrich S, Rasche M, Schöning J, Reimer C, Keihani S, Maroz A, Xie Y, Li Z, Schambach A, Reinhardt D, Klusmann JH. miR-99a/100~125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFß and Wnt signaling. Genes Dev. 2014 Apr 15; 28(8):858-74. PMID: 24736844.
    Citations: 40     Fields:    Translation:HumansAnimalsCells
  112. Bobis-Wozowicz S, Galla M, Alzubi J, Kuehle J, Baum C, Schambach A, Cathomen T. Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery. Sci Rep. 2014 Apr 11; 4:4656. PMID: 24722320.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  113. Kustikova OS, Stahlhut M, Ha TC, Scherer R, Schambach A, Baum C. Dose response and clonal variability of lentiviral tetracycline-regulated vectors in murine hematopoietic cells. Exp Hematol. 2014 Jul; 42(7):505-515.e7. PMID: 24674753.
    Citations: 3     Fields:    Translation:AnimalsCells
  114. Braun CJ, Boztug K, Paruzynski A, Witzel M, Schwarzer A, Rothe M, Modlich U, Beier R, Göhring G, Steinemann D, Fronza R, Ball CR, Haemmerle R, Naundorf S, Kühlcke K, Rose M, Fraser C, Mathias L, Ferrari R, Abboud MR, Al-Herz W, Kondratenko I, Maródi L, Glimm H, Schlegelberger B, Schambach A, Albert MH, Schmidt M, von Kalle C, Klein C. Gene therapy for Wiskott-Aldrich syndrome--long-term efficacy and genotoxicity. Sci Transl Med. 2014 Mar 12; 6(227):227ra33. PMID: 24622513.
    Citations: 100     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  115. Maetzig T, Kuehle J, Schwarzer A, Turan S, Rothe M, Chaturvedi A, Morgan M, Ha TC, Heuser M, Hammerschmidt W, Baum C, Schambach A. All-in-One inducible lentiviral vector systems based on drug controlled FLP recombinase. Biomaterials. 2014 May; 35(14):4345-56. PMID: 24529624.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  116. Wunderlich S, Kircher M, Vieth B, Haase A, Merkert S, Beier J, Göhring G, Glage S, Schambach A, Curnow EC, Pääbo S, Martin U, Enard W. Primate iPS cells as tools for evolutionary analyses. Stem Cell Res. 2014 May; 12(3):622-9. PMID: 24631741.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  117. Kuehle J, Turan S, Cantz T, Hoffmann D, Suerth JD, Maetzig T, Zychlinski D, Klein C, Steinemann D, Baum C, Bode J, Schambach A. Modified lentiviral LTRs allow Flp recombinase-mediated cassette exchange and in vivo tracing of "factor-free" induced pluripotent stem cells. Mol Ther. 2014 May; 22(5):919-28. PMID: 24434935.
    Citations: 13     Fields:    Translation:AnimalsCells
  118. Lachmann N, Happle C, Ackermann M, Lüttge D, Wetzke M, Merkert S, Hetzel M, Kensah G, Jara-Avaca M, Mucci A, Skuljec J, Dittrich AM, Pfaff N, Brennig S, Schambach A, Steinemann D, Göhring G, Cantz T, Martin U, Schwerk N, Hansen G, Moritz T. Gene correction of human induced pluripotent stem cells repairs the cellular phenotype in pulmonary alveolar proteinosis. Am J Respir Crit Care Med. 2014 Jan 15; 189(2):167-82. PMID: 24279725.
    Citations: 22     Fields:    Translation:HumansCells
  119. Rothe M, Schambach A, Biasco L. Safety of gene therapy: new insights to a puzzling case. Curr Gene Ther. 2014; 14(6):429-36. PMID: 25245088.
    Citations: 9     Fields:    Translation:HumansAnimals
  120. Rothe M, Modlich U, Schambach A. Biosafety challenges for use of lentiviral vectors in gene therapy. Curr Gene Ther. 2013 Dec; 13(6):453-68. PMID: 24195603.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  121. Ackermann M, Lachmann N, Hartung S, Eggenschwiler R, Pfaff N, Happle C, Mucci A, Göhring G, Niemann H, Hansen G, Schambach A, Cantz T, Zweigerdt R, Moritz T. Promoter and lineage independent anti-silencing activity of the A2 ubiquitous chromatin opening element for optimized human pluripotent stem cell-based gene therapy. Biomaterials. 2014 Feb; 35(5):1531-42. PMID: 24290698.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  122. Zwingenberger S, Yao Z, Jacobi A, Vater C, Valladares RD, Li C, Nich C, Rao AJ, Christman JE, Antonios JK, Gibon E, Schambach A, Maetzig T, Goodman SB, Stiehler M. Enhancement of BMP-2 induced bone regeneration by SDF-1a mediated stem cell recruitment. Tissue Eng Part A. 2014 Feb; 20(3-4):810-8. PMID: 24090366.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  123. Hauber I, Hofmann-Sieber H, Chemnitz J, Dubrau D, Chusainow J, Stucka R, Hartjen P, Schambach A, Ziegler P, Hackmann K, Schröck E, Schumacher U, Lindner C, Grundhoff A, Baum C, Manz MG, Buchholz F, Hauber J. Highly significant antiviral activity of HIV-1 LTR-specific tre-recombinase in humanized mice. PLoS Pathog. 2013; 9(9):e1003587. PMID: 24086129.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  124. Gupta SS, Maetzig T, Maertens GN, Sharif A, Rothe M, Weidner-Glunde M, Galla M, Schambach A, Cherepanov P, Schulz TF. Bromo- and extraterminal domain chromatin regulators serve as cofactors for murine leukemia virus integration. J Virol. 2013 Dec; 87(23):12721-36. PMID: 24049186.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  125. Kaufmann KB, Büning H, Galy A, Schambach A, Grez M. Gene therapy on the move. EMBO Mol Med. 2013 11; 5(11):1642-61. PMID: 24106209.
    Citations: 34     Fields:    Translation:Humans
  126. Mandel K, Yang Y, Schambach A, Glage S, Otte A, Hass R. Mesenchymal stem cells directly interact with breast cancer cells and promote tumor cell growth in vitro and in vivo. Stem Cells Dev. 2013 Dec 01; 22(23):3114-27. PMID: 23895436.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  127. Eggenschwiler R, Loya K, Wu G, Sharma AD, Sgodda M, Zychlinski D, Herr C, Steinemann D, Teckman J, Bals R, Ott M, Schambach A, Schöler HR, Cantz T. Sustained knockdown of a disease-causing gene in patient-specific induced pluripotent stem cells using lentiviral vector-based gene therapy. Stem Cells Transl Med. 2013 Sep; 2(9):641-54. PMID: 23926210.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  128. Schambach A, Moritz T. Toward position-independent retroviral vector expression in pluripotent stem cells. Mol Ther. 2013 Aug; 21(8):1474-7. PMID: 23903574.
    Citations:    Fields:    Translation:AnimalsCells
  129. Gürlevik E, Fleischmann-Mundt B, Armbrecht N, Longerich T, Woller N, Kloos A, Hoffmann D, Schambach A, Wirth TC, Manns MP, Zender L, Kubicka S, Kühnel F. Adjuvant gemcitabine therapy improves survival in a locally induced, R0-resectable model of metastatic intrahepatic cholangiocarcinoma. Hepatology. 2013 Sep; 58(3):1031-41. PMID: 23686746.
    Citations: 9     Fields:    Translation:Animals
  130. Stein S, Scholz S, Schwäble J, Sadat MA, Modlich U, Schultze-Strasser S, Diaz M, Chen-Wichmann L, Müller-Kuller U, Brendel C, Fronza R, Kaufmann KB, Naundorf S, Pech NK, Travers JB, Matute JD, Presson RG, Sandusky GE, Kunkel H, Rudolf E, Dillmann A, von Kalle C, Kühlcke K, Baum C, Schambach A, Dinauer MC, Schmidt M, Grez M. From bench to bedside: preclinical evaluation of a self-inactivating gammaretroviral vector for the gene therapy of X-linked chronic granulomatous disease. Hum Gene Ther Clin Dev. 2013 Jun; 24(2):86-98. PMID: 23845071.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  131. Rittelmeyer I, Rothe M, Brugman MH, Iken M, Schambach A, Manns MP, Baum C, Modlich U, Ott M. Hepatic lentiviral gene transfer is associated with clonal selection, but not with tumor formation in serially transplanted rodents. Hepatology. 2013 Jul; 58(1):397-408. PMID: 23258554.
    Citations: 12     Fields:    Translation:AnimalsCells
  132. Brugman MH, Suerth JD, Rothe M, Suerbaum S, Schambach A, Modlich U, Kustikova O, Baum C. Evaluating a ligation-mediated PCR and pyrosequencing method for the detection of clonal contribution in polyclonal retrovirally transduced samples. Hum Gene Ther Methods. 2013 Apr; 24(2):68-79. PMID: 23384086.
    Citations: 12     Fields:    Translation:AnimalsCells
  133. Pfaff N, Lachmann N, Ackermann M, Kohlscheen S, Brendel C, Maetzig T, Niemann H, Antoniou MN, Grez M, Schambach A, Cantz T, Moritz T. A ubiquitous chromatin opening element prevents transgene silencing in pluripotent stem cells and their differentiated progeny. Stem Cells. 2013 Mar; 31(3):488-99. PMID: 23307570.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  134. Kotlarz D, Zietara N, Uzel G, Weidemann T, Braun CJ, Diestelhorst J, Krawitz PM, Robinson PN, Hecht J, Puchalka J, Gertz EM, Schäffer AA, Lawrence MG, Kardava L, Pfeifer D, Baumann U, Pfister ED, Hanson EP, Schambach A, Jacobs R, Kreipe H, Moir S, Milner JD, Schwille P, Mundlos S, Klein C. Loss-of-function mutations in the IL-21 receptor gene cause a primary immunodeficiency syndrome. J Exp Med. 2013 Mar 11; 210(3):433-43. PMID: 23440042.
    Citations: 51     Fields:    Translation:HumansCells
  135. Sundarasetty BS, Singh VK, Salguero G, Geffers R, Rickmann M, Macke L, Borchers S, Figueiredo C, Schambach A, Gullberg U, Provasi E, Bonini C, Ganser A, Woelfel T, Stripecke R. Lentivirus-induced dendritic cells for immunization against high-risk WT1(+) acute myeloid leukemia. Hum Gene Ther. 2013 Feb; 24(2):220-37. PMID: 23311414.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  136. Schambach A, Zychlinski D, Ehrnstroem B, Baum C. Biosafety features of lentiviral vectors. Hum Gene Ther. 2013 Feb; 24(2):132-42. PMID: 23311447.
    Citations: 21     Fields:    Translation:HumansCells
  137. Galla M, Schambach A, Baum C. Retrovirus-based mRNA transfer for transient cell manipulation. Methods Mol Biol. 2013; 969:139-61. PMID: 23296933.
    Citations: 4     Fields:    Translation:AnimalsCells
  138. Grabundzija I, Wang J, Sebe A, Erdei Z, Kajdi R, Devaraj A, Steinemann D, Szuhai K, Stein U, Cantz T, Schambach A, Baum C, Izsvák Z, Sarkadi B, Ivics Z. Sleeping Beauty transposon-based system for cellular reprogramming and targeted gene insertion in induced pluripotent stem cells. Nucleic Acids Res. 2013 Feb 01; 41(3):1829-47. PMID: 23275558.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  139. Zwingenberger S, Yao Z, Jacobi A, Vater C, Valladares RD, Li C, Nich C, Rao AJ, Christman JE, Antonios JK, Gibon E, Schambach A, Mätzig T, Günther KP, Goodman SB, Stiehler M. Stem cell attraction via SDF-1a expressing fat tissue grafts. J Biomed Mater Res A. 2013 Jul; 101(7):2067-74. PMID: 23281045.
    Citations: 3     Fields:    Translation:AnimalsCells
  140. Kaufmann KB, Brendel C, Suerth JD, Mueller-Kuller U, Chen-Wichmann L, Schwäble J, Pahujani S, Kunkel H, Schambach A, Baum C, Grez M. Alpharetroviral vector-mediated gene therapy for X-CGD: functional correction and lack of aberrant splicing. Mol Ther. 2013 Mar; 21(3):648-61. PMID: 23207695.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  141. Wiedemann A, Hemmer K, Bernemann I, Göhring G, Pogozhykh O, Figueiredo C, Glage S, Schambach A, Schwamborn JC, Blasczyk R, Müller T. Induced pluripotent stem cells generated from adult bone marrow-derived cells of the nonhuman primate (Callithrix jacchus) using a novel quad-cistronic and excisable lentiviral vector. Cell Reprogram. 2012 Dec; 14(6):485-96. PMID: 23194452.
    Citations: 10     Fields:    Translation:AnimalsCells
  142. Wunderlich S, Haase A, Merkert S, Beier J, Schwanke K, Schambach A, Glage S, Göhring G, Curnow EC, Martin U. Induction of pluripotent stem cells from a cynomolgus monkey using a polycistronic simian immunodeficiency virus-based vector, differentiation toward functional cardiomyocytes, and generation of stably expressing reporter lines. Cell Reprogram. 2012 Dec; 14(6):471-84. PMID: 23194451.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  143. Maetzig T, Baum C, Schambach A. Retroviral protein transfer: falling apart to make an impact. Curr Gene Ther. 2012 Oct; 12(5):389-409. PMID: 22934617.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  144. Schambach A, Baum C. Vectorizing mRNA and proteins. Curr Gene Ther. 2012 Oct; 12(5):345-6. PMID: 23211015.
    Citations:    Fields:    Translation:HumansAnimals
  145. Suerth JD, Schambach A, Baum C. Genetic modification of lymphocytes by retrovirus-based vectors. Curr Opin Immunol. 2012 Oct; 24(5):598-608. PMID: 22995202.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  146. Zhou Q, Schneider IC, Edes I, Honegger A, Bach P, Schönfeld K, Schambach A, Wels WS, Kneissl S, Uckert W, Buchholz CJ. T-cell receptor gene transfer exclusively to human CD8(+) cells enhances tumor cell killing. Blood. 2012 Nov 22; 120(22):4334-42. PMID: 22898597.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  147. Weinacht KG, Brauer PM, Felgentreff K, Devine A, Gennery AR, Giliani S, Al-Herz W, Schambach A, Zúñiga-Pflücker JC, Notarangelo LD. The role of induced pluripotent stem cells in research and therapy of primary immunodeficiencies. Curr Opin Immunol. 2012 Oct; 24(5):617-24. PMID: 22841347.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  148. Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÁ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, Zhou D, Griffin JH, Baum C, Weiler H, Hauer-Jensen M. Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity. Nat Med. 2012 Jul; 18(7):1123-9. PMID: 22729286.
    Citations: 49     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  149. Daenthanasanmak A, Salguero G, Borchers S, Figueiredo C, Jacobs R, Sundarasetty BS, Schneider A, Schambach A, Eiz-Vesper B, Blasczyk R, Weissinger EM, Ganser A, Stripecke R. Integrase-defective lentiviral vectors encoding cytokines induce differentiation of human dendritic cells and stimulate multivalent immune responses in vitro and in vivo. Vaccine. 2012 Jul 20; 30(34):5118-31. PMID: 22691433.
    Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  150. Otte A, Göhring G, Steinemann D, Schlegelberger B, Groos S, Länger F, Kreipe HH, Schambach A, Neumann T, Hillemanns P, Park-Simon TW, Hass R. A tumor-derived population (SCCOHT-1) as cellular model for a small cell ovarian carcinoma of the hypercalcemic type. Int J Oncol. 2012 Aug; 41(2):765-75. PMID: 22581215.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  151. Thol F, Yun H, Sonntag AK, Damm F, Weissinger EM, Krauter J, Wagner K, Morgan M, Wichmann M, Göhring G, Bug G, Ottmann O, Hofmann WK, Schambach A, Schlegelberger B, Haferlach T, Bowen D, Mills K, Ganser A, Heuser M. Prognostic significance of combined MN1, ERG, BAALC, and EVI1 (MEBE) expression in patients with myelodysplastic syndromes. Ann Hematol. 2012 Aug; 91(8):1221-33. PMID: 22488406.
    Citations: 8     Fields:    Translation:Humans
  152. Wang J, Sun Q, Morita Y, Jiang H, Gross A, Lechel A, Hildner K, Guachalla LM, Gompf A, Hartmann D, Schambach A, Wuestefeld T, Dauch D, Schrezenmeier H, Hofmann WK, Nakauchi H, Ju Z, Kestler HA, Zender L, Rudolph KL. A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage. Cell. 2012 Mar 02; 148(5):1001-14. PMID: 22385964.
    Citations: 116     Fields:    Translation:HumansAnimalsCells
  153. Müller LU, Milsom MD, Harris CE, Vyas R, Brumme KM, Parmar K, Moreau LA, Schambach A, Park IH, London WB, Strait K, Schlaeger T, Devine AL, Grassman E, D'Andrea A, Daley GQ, Williams DA. Overcoming reprogramming resistance of Fanconi anemia cells. Blood. 2012 Jun 07; 119(23):5449-57. PMID: 22371882.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  154. Suerth JD, Maetzig T, Brugman MH, Heinz N, Appelt JU, Kaufmann KB, Schmidt M, Grez M, Modlich U, Baum C, Schambach A. Alpharetroviral self-inactivating vectors: long-term transgene expression in murine hematopoietic cells and low genotoxicity. Mol Ther. 2012 May; 20(5):1022-32. PMID: 22334016.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  155. Koch L, Deiwick A, Schlie S, Michael S, Gruene M, Coger V, Zychlinski D, Schambach A, Reimers K, Vogt PM, Chichkov B. Skin tissue generation by laser cell printing. Biotechnol Bioeng. 2012 Jul; 109(7):1855-63. PMID: 22328297.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  156. Abdollahpour H, Appaswamy G, Kotlarz D, Diestelhorst J, Beier R, Schäffer AA, Gertz EM, Schambach A, Kreipe HH, Pfeifer D, Engelhardt KR, Rezaei N, Grimbacher B, Lohrmann S, Sherkat R, Klein C. The phenotype of human STK4 deficiency. Blood. 2012 Apr 12; 119(15):3450-7. PMID: 22294732.
    Citations: 67     Fields:    Translation:HumansCells
  157. Brennig S, Rattmann I, Lachmann N, Schambach A, Williams DA, Moritz T. In vivo enrichment of cytidine deaminase gene-modified hematopoietic cells by prolonged cytosine-arabinoside application. Cytotherapy. 2012 Apr; 14(4):451-60. PMID: 22242831.
    Citations: 4     Fields:    Translation:AnimalsCells
  158. Voelkel C, Galla M, Dannhauser PN, Maetzig T, Sodeik B, Schambach A, Baum C. Pseudotype-independent nonspecific uptake of gammaretroviral and lentiviral particles in human cells. Hum Gene Ther. 2012 Mar; 23(3):274-86. PMID: 22010882.
    Citations: 7     Fields:    Translation:HumansCells
  159. Abdulkerim E, Baganz S, Schambach A, Kasper C, Scheper T. Production and purification of TGFb-1 in CHO-Cells. BMC Proc. 2011; 5 Suppl 8:P134. PMID: 22373440.
    Citations:    
  160. Knippenberg S, Thau N, Schwabe K, Dengler R, Schambach A, Hass R, Petri S. Intraspinal injection of human umbilical cord blood-derived cells is neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis. Neurodegener Dis. 2012; 9(3):107-20. PMID: 22122965.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  161. Haake C, Bonk S, Parsiegla J, Tomala M, Loya K, Sgodda M, Cantz T, Schambach A, Kasper C, Scheper T. Comparison of the activity and pluripotency maintaining potential of human leukemia inhibitory factor (LIF) produced in E.coli and CHO cells. BMC Proc. 2011; 5 Suppl 8:P109. PMID: 22373201.
    Citations:    
  162. Pfaff N, Fiedler J, Holzmann A, Schambach A, Moritz T, Cantz T, Thum T. miRNA screening reveals a new miRNA family stimulating iPS cell generation via regulation of Meox2. EMBO Rep. 2011 Oct 28; 12(11):1153-9. PMID: 21941297.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  163. Jaako P, Flygare J, Olsson K, Quere R, Ehinger M, Henson A, Ellis S, Schambach A, Baum C, Richter J, Larsson J, Bryder D, Karlsson S. Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia. Blood. 2011 Dec 01; 118(23):6087-96. PMID: 21989989.
    Citations: 40     Fields:    Translation:AnimalsCells
  164. Schott JW, Galla M, Godinho T, Baum C, Schambach A. Viral and non-viral approaches for transient delivery of mRNA and proteins. Curr Gene Ther. 2011 Oct; 11(5):382-98. PMID: 21787295.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  165. Li W, Wang X, Fan W, Zhao P, Chan YC, Chen S, Zhang S, Guo X, Zhang Y, Li Y, Cai J, Qin D, Li X, Yang J, Peng T, Zychlinski D, Hoffmann D, Zhang R, Deng K, Ng KM, Menten B, Zhong M, Wu J, Li Z, Chen Y, Schambach A, Tse HF, Pei D, Esteban MA. Modeling abnormal early development with induced pluripotent stem cells from aneuploid syndromes. Hum Mol Genet. 2012 Jan 01; 21(1):32-45. PMID: 21949351.
    Citations: 21     Fields:    Translation:HumansCells
  166. Avedillo Díez I, Zychlinski D, Coci EG, Galla M, Modlich U, Dewey RA, Schwarzer A, Maetzig T, Mpofu N, Jaeckel E, Boztug K, Baum C, Klein C, Schambach A. Development of novel efficient SIN vectors with improved safety features for Wiskott-Aldrich syndrome stem cell based gene therapy. Mol Pharm. 2011 Oct 03; 8(5):1525-37. PMID: 21851067.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  167. Pfaff N, Lachmann N, Kohlscheen S, Sgodda M, Araúzo-Bravo MJ, Greber B, Kues W, Glage S, Baum C, Niemann H, Schambach A, Cantz T, Moritz T. Efficient hematopoietic redifferentiation of induced pluripotent stem cells derived from primitive murine bone marrow cells. Stem Cells Dev. 2012 Mar 20; 21(5):689-701. PMID: 21732815.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  168. Huston MW, van Til NP, Visser TP, Arshad S, Brugman MH, Cattoglio C, Nowrouzi A, Li Y, Schambach A, Schmidt M, Baum C, von Kalle C, Mavilio F, Zhang F, Blundell MP, Thrasher AJ, Verstegen MM, Wagemaker G. Correction of murine SCID-X1 by lentiviral gene therapy using a codon-optimized IL2RG gene and minimal pretransplant conditioning. Mol Ther. 2011 Oct; 19(10):1867-77. PMID: 21750532.
    Citations: 14     Fields:    Translation:AnimalsCells
  169. Wu G, Liu N, Rittelmeyer I, Sharma AD, Sgodda M, Zaehres H, Bleidissel M, Greber B, Gentile L, Han DW, Rudolph C, Steinemann D, Schambach A, Ott M, Schöler HR, Cantz T. Generation of healthy mice from gene-corrected disease-specific induced pluripotent stem cells. PLoS Biol. 2011 Jul; 9(7):e1001099. PMID: 21765802.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  170. Maetzig T, Galla M, Baum C, Schambach A. Gammaretroviral vectors: biology, technology and application. Viruses. 2011 06; 3(6):677-713. PMID: 21994751.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  171. Galla M, Schambach A, Falk CS, Maetzig T, Kuehle J, Lange K, Zychlinski D, Heinz N, Brugman MH, Göhring G, Izsvák Z, Ivics Z, Baum C. Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery. Nucleic Acids Res. 2011 Sep 01; 39(16):7147-60. PMID: 21609958.
    Citations: 21     Fields: