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Hsiao-Ying Wey, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21DA047133 (WEY, HSIAO-YING) Jun 15, 2018 - Jun 30, 2020
    NIH/NIDA
    Measure Mu-opioid Receptor Desensitization in vivo
    Role: Principal Investigator
  2. R00DA037928 (WEY, HSIAO-YING) Sep 1, 2016 - Aug 31, 2019
    NIH/NIDA
    Assessing Dynamic Opioid-Dopamine Interactions Using Simultaneous PET/MRI
    Role: Principal Investigator
  3. K99DA037928 (WEY, HSIAO-YING) Jul 15, 2014 - Jun 30, 2016
    NIH/NIDA
    Assessing Dynamic Opioid-Dopamine Interactions Using Simultaneous PET/MRI
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM. PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia. J Clin Invest. 2019 Jan 02; 129(1):364-372. PMID: 30530989.
    Citations:    Fields:    
  2. Placzek MS, Schroeder FA, Che T, Wey HY, Neelamegam R, Wang C, Roth BL, Hooker JM. Discrepancies in Kappa Opioid Agonist Binding Revealed through PET Imaging. ACS Chem Neurosci. 2019 Jan 16; 10(1):384-395. PMID: 30212182.
    Citations:    Fields:    
  3. Gale EM, Wey HY, Ramsay I, Yen YF, Sosnovik DE, Caravan P. A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism. Radiology. 2018 03; 286(3):865-872. PMID: 29117483.
    Citations: 1     Fields:    Translation:Animals
  4. Van de Bittner GC, Van de Bittner KC, Wey HY, Rowe W, Dharanipragada R, Ying X, Hurst W, Giovanni A, Alving K, Gupta A, Hoekman J, Hooker JM. Positron Emission Tomography Assessment of the Intranasal Delivery Route for Orexin A. ACS Chem Neurosci. 2018 02 21; 9(2):358-368. PMID: 29035509.
    Citations:    Fields:    Translation:AnimalsCells
  5. Sander CY, Mandeville JB, Wey HY, Catana C, Hooker JM, Rosen BR. Effects of flow changes on radiotracer binding: Simultaneous measurement of neuroreceptor binding and cerebral blood flow modulation. J Cereb Blood Flow Metab. 2019 Jan; 39(1):131-146. PMID: 28816571.
    Citations: 3     Fields:    
  6. Hooker JM, Strebl MG, Schroeder FA, Wey HY, Ambardekar AV, McKinsey TA, Schoenberger M. Imaging cardiac SCN5A using the novel F-18 radiotracer radiocaine. Sci Rep. 2017 02 16; 7:42136. PMID: 28205593.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Kochunov P, Wey HY, Fox PT, Lancaster JL, Davis MD, Wang DJ, Lin AL, Bastarrachea RA, Andrade MC, Mattern V, Frost P, Higgins PB, Comuzzie AG, Voruganti VS. Changes in Cerebral Blood Flow during an Alteration in Glycemic State in a Large Non-human Primate (Papio hamadryas sp.). Front Neurosci. 2017; 11:49. PMID: 28261040.
    Citations: 2     
  8. Van de Bittner GC, Riley MM, Cao L, Ehses J, Herrick SP, Ricq EL, Wey HY, O'Neill MJ, Ahmed Z, Murray TK, Smith JE, Wang C, Schroeder FA, Albers MW, Hooker JM. Nasal neuron PET imaging quantifies neuron generation and degeneration. J Clin Invest. 2017 Feb 01; 127(2):681-694. PMID: 28112682.
    Citations: 2     Fields:    Translation:Animals
  9. Keliher EJ, Ye YX, Wojtkiewicz GR, Aguirre AD, Tricot B, Senders ML, Groenen H, Fay F, Perez-Medina C, Calcagno C, Carlucci G, Reiner T, Sun Y, Courties G, Iwamoto Y, Kim HY, Wang C, Chen JW, Swirski FK, Wey HY, Hooker J, Fayad ZA, Mulder WJ, Weissleder R, Nahrendorf M. Polyglucose nanoparticles with renal elimination and macrophage avidity facilitate PET imaging in ischaemic heart disease. Nat Commun. 2017 01 16; 8:14064. PMID: 28091604.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  10. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The Modulation Effect of Longitudinal Acupuncture on Resting State Functional Connectivity in Knee Osteoarthritis Patients. Mol Pain. 2015 01; 11. PMID: 27655921.
    Citations:    
  11. Wey HY, Gilbert TM, Zürcher NR, She A, Bhanot A, Taillon BD, Schroeder FA, Wang C, Haggarty SJ, Hooker JM. Insights into neuroepigenetics through human histone deacetylase PET imaging. Sci Transl Med. 2016 08 10; 8(351):351ra106. PMID: 27510902.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  12. Mandeville JB, Sander CYM, Wey HY, Hooker JM, Hansen HD, Svarer C, Knudsen GM, Rosen BR. A regularized full reference tissue model for PET neuroreceptor mapping. Neuroimage. 2016 Oct 01; 139:405-414. PMID: 27364474.
    Citations:    Fields:    Translation:HumansAnimals
  13. Placzek MS, Zhao W, Wey HY, Morin TM, Hooker JM. PET Neurochemical Imaging Modes. Semin Nucl Med. 2016 Jan; 46(1):20-7. PMID: 26687854.
    Citations: 2     Fields:    Translation:HumansAnimals
  14. Strebl MG, Wang C, Schroeder FA, Placzek MS, Wey HY, Van de Bittner GC, Neelamegam R, Hooker JM. Development of a Fluorinated Class-I HDAC Radiotracer Reveals Key Chemical Determinants of Brain Penetrance. ACS Chem Neurosci. 2016 05 18; 7(5):528-33. PMID: 26675505.
    Citations: 3     Fields:    Translation:Animals
  15. Chen X, Spaeth RB, Freeman SG, Scarborough DM, Hashmi JA, Wey HY, Egorova N, Vangel M, Mao J, Wasan AD, Edwards RR, Gollub RL, Kong J. The modulation effect of longitudinal acupuncture on resting state functional connectivity in knee osteoarthritis patients. Mol Pain. 2015 Oct 29; 11:67. PMID: 26511911.
    Citations: 12     Fields:    Translation:HumansCTClinical Trials
  16. Placzek MS, Van de Bittner GC, Wey HY, Lukas SE, Hooker JM. Immediate and Persistent Effects of Salvinorin A on the Kappa Opioid Receptor in Rodents, Monitored In Vivo with PET. Neuropsychopharmacology. 2015 Dec; 40(13):2865-72. PMID: 26058662.
    Citations: 1     Fields:    Translation:AnimalsCells
  17. Wey HY, Wang C, Schroeder FA, Logan J, Price JC, Hooker JM. Kinetic Analysis and Quantification of [¹¹C]Martinostat for in Vivo HDAC Imaging of the Brain. ACS Chem Neurosci. 2015 May 20; 6(5):708-15. PMID: 25768025.
    Citations: 5     Fields:    Translation:Animals
  18. Wey HY, Phillips KA, McKay DR, Laird AR, Kochunov P, Davis MD, Glahn DC, Blangero J, Duong TQ, Fox PT. Erratum to: Multi-region hemispheric specialization differentiates human from nonhuman primate brain function. Brain Struct Funct. 2014 Nov; 219(6):2195. PMID: 24046185.
    Citations:    
  19. Schroeder FA, Wang C, Van de Bittner GC, Neelamegam R, Takakura WR, Karunakaran A, Wey HY, Reis SA, Gale J, Zhang YL, Holson EB, Haggarty SJ, Hooker JM. PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat. ACS Chem Neurosci. 2014 Oct 15; 5(10):1055-62. PMID: 25188794.
    Citations: 4     Fields:    Translation:Animals
  20. Wang C, Schroeder FA, Wey HY, Borra R, Wagner FF, Reis S, Kim SW, Holson EB, Haggarty SJ, Hooker JM. In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs. J Med Chem. 2014 Oct 09; 57(19):7999-8009. PMID: 25203558.
    Citations: 12     Fields:    Translation:HumansAnimals
  21. Wey HY, Catana C, Hooker JM, Dougherty DD, Knudsen GM, Wang DJ, Chonde DB, Rosen BR, Gollub RL, Kong J. Simultaneous fMRI-PET of the opioidergic pain system in human brain. Neuroimage. 2014 Nov 15; 102 Pt 2:275-82. PMID: 25107855.
    Citations: 11     Fields:    Translation:Humans
  22. Rotstein BH, Wey HY, Shoup TM, Wilson AA, Liang SH, Hooker JM, Vasdev N. PET imaging of fatty acid amide hydrolase with [(18)F]DOPP in nonhuman primates. Mol Pharm. 2014 Nov 03; 11(11):3832-8. PMID: 25004399.
    Citations: 3     Fields:    Translation:Animals
  23. Villien M, Wey HY, Mandeville JB, Catana C, Polimeni JR, Sander CY, Zürcher NR, Chonde DB, Fowler JS, Rosen BR, Hooker JM. Dynamic functional imaging of brain glucose utilization using fPET-FDG. Neuroimage. 2014 Oct 15; 100:192-9. PMID: 24936683.
    Citations: 13     Fields:    Translation:HumansAnimals
  24. Ren H, Wey HY, Strebl M, Neelamegam R, Ritter T, Hooker JM. Synthesis and imaging validation of [¹8F]MDL100907 enabled by Ni-mediated fluorination. ACS Chem Neurosci. 2014 Jul 16; 5(7):611-5. PMID: 24845956.
    Citations: 7     Fields:    Translation:AnimalsCells
  25. Kong J, Spaeth RB, Wey HY, Cheetham A, Cook AH, Jensen K, Tan Y, Liu H, Wang D, Loggia ML, Napadow V, Smoller JW, Wasan AD, Gollub RL. S1 is associated with chronic low back pain: a functional and structural MRI study. Mol Pain. 2013 Aug 21; 9:43. PMID: 23965184.
    Citations: 10     Fields:    Translation:Humans
  26. Wey HY, Desai VR, Duong TQ. A review of current imaging methods used in stroke research. Neurol Res. 2013 Dec; 35(10):1092-102. PMID: 24070268.
    Citations: 3     Fields:    Translation:HumansAnimals
  27. Wey HY, Phillips KA, McKay DR, Laird AR, Kochunov P, Davis MD, Glahn DC, Blangero J, Duong TQ, Fox PT. Multi-region hemispheric specialization differentiates human from nonhuman primate brain function. Brain Struct Funct. 2014 Nov; 219(6):2187-94. PMID: 23928747.
    Citations: 10     Fields:    Translation:HumansAnimals
  28. Kong J, Jensen K, Loiotile R, Cheetham A, Wey HY, Tan Y, Rosen B, Smoller JW, Kaptchuk TJ, Gollub RL. Functional connectivity of the frontoparietal network predicts cognitive modulation of pain. Pain. 2013 Mar; 154(3):459-67. PMID: 23352757.
    Citations: 34     Fields:    Translation:Humans
  29. Huerta C, Li J, Wey H, Duong T. SU-E-I-72: Modulation of Hypothalamic Connectivity by Food Ingestion. Med Phys. 2012 Jun; 39(6Part5):3641. PMID: 28517643.
    Citations:    Fields:    
  30. Wey HY, Duong TQ. Multimodal MRI of nonhuman primate stroke. Transl Stroke Res. 2012 Mar; 3(1):84-9. PMID: 24323756.
    Citations: 1     Fields:    
  31. Wey HY, Kroma GM, Li J, Leland MM, Jones L, Duong TQ. MRI of perfusion-diffusion mismatch in non-human primate (baboon) stroke: a preliminary report. Open Neuroimag J. 2011; 5:147-52. PMID: 22253656.
    Citations: 3     
  32. Salinas FS, Szabó CÁ, Zhang W, Jones L, Leland MM, Wey HY, Duong TQ, Fox PT, Narayana S. Functional neuroimaging of the baboon during concurrent image-guided transcranial magnetic stimulation. Neuroimage. 2011 Aug 15; 57(4):1393-401. PMID: 21664276.
    Citations: 7     Fields:    Translation:Animals
  33. Zhang Y, Wey HY, San Emeterio Nateras O, Peng Q, De La Garza BH, Duong TQ. Anatomical, blood oxygenation level-dependent, and blood flow MRI of nonhuman primate (baboon) retina. Magn Reson Med. 2011 Aug; 66(2):546-54. PMID: 21360746.
    Citations: 3     Fields:    Translation:Animals
  34. Shih YY, Wey HY, De La Garza BH, Duong TQ. Striatal and cortical BOLD, blood flow, blood volume, oxygen consumption, and glucose consumption changes in noxious forepaw electrical stimulation. J Cereb Blood Flow Metab. 2011 Mar; 31(3):832-41. PMID: 20940730.
    Citations: 15     Fields:    Translation:Animals
  35. Wey HY, Wang DJ, Duong TQ. Baseline CBF, and BOLD, CBF, and CMRO2 fMRI of visual and vibrotactile stimulations in baboons. J Cereb Blood Flow Metab. 2011 Feb; 31(2):715-24. PMID: 20827260.
    Citations: 20     Fields:    Translation:Animals
  36. Kochunov P, Castro C, Davis DM, Dudley D, Wey HY, Purdy D, Fox PT, Simerly C, Schatten G. Fetal brain during a binge drinking episode: a dynamic susceptibility contrast MRI fetal brain perfusion study. Neuroreport. 2010 Jul 14; 21(10):716-21. PMID: 20505549.
    Citations: 7     Fields:    Translation:Animals
  37. Wey HY, Li J, Szabó CA, Fox PT, Leland MM, Jones L, Duong TQ. BOLD fMRI of visual and somatosensory-motor stimulations in baboons. Neuroimage. 2010 Oct 01; 52(4):1420-7. PMID: 20471483.
    Citations: 10     Fields:    Translation:Animals
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.