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profileYosef Maruvka, Ph.D.

TitleResearch Fellow in Medicine (EXT)
InstitutionMassachusetts General Hospital
DepartmentMedicine
AddressMassachusetts General Hospital
Cancer Ctr - 7
149 13th Street
Charlestown MA 02129
Phone617/726-5613
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Other Positions
TitlePostdoctoral Research Fellow
InstitutionHarvard T.H. Chan School of Public Health
DepartmentBiostatistics


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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Polak P, Kim J, Braunstein LZ, Karlic R, Haradhavala NJ, Tiao G, Rosebrock D, Livitz D, K├╝bler K, Mouw KW, Kamburov A, Maruvka YE, Leshchiner I, Lander ES, Golub TR, Zick A, Orthwein A, Lawrence MS, Batra RN, Caldas C, Haber DA, Laird PW, Shen H, Ellisen LW, D'Andrea AD, Chanock SJ, Foulkes WD, Getz G. A mutational signature reveals alterations underlying deficient homologous recombination repair in breast cancer. Nat Genet. 2017 Aug 21. PMID: 28825726.
    View in: PubMed
  2. Rheinbay E, Parasuraman P, Grimsby J, Tiao G, Engreitz JM, Kim J, Lawrence MS, Taylor-Weiner A, Rodriguez-Cuevas S, Rosenberg M, Hess J, Stewart C, Maruvka YE, Stojanov P, Cortes ML, Seepo S, Cibulskis C, Tracy A, Pugh TJ, Lee J, Zheng Z, Ellisen LW, Iafrate AJ, Boehm JS, Gabriel SB, Meyerson M, Golub TR, Baselga J, Hidalgo-Miranda A, Shioda T, Bernards A, Lander ES, Getz G. Recurrent and functional regulatory mutations in breast cancer. Nature. 2017 07 06; 547(7661):55-60. PMID: 28658208.
    View in: PubMed
  3. Hata AN, Niederst MJ, Archibald HL, Gomez-Caraballo M, Siddiqui FM, Mulvey HE, Maruvka YE, Ji F, Bhang HE, Krishnamurthy Radhakrishna V, Siravegna G, Hu H, Raoof S, Lockerman E, Kalsy A, Lee D, Keating CL, Ruddy DA, Damon LJ, Crystal AS, Costa C, Piotrowska Z, Bardelli A, Iafrate AJ, Sadreyev RI, Stegmeier F, Getz G, Sequist LV, Faber AC, Engelman JA. Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition. Nat Med. 2016 Mar; 22(3):262-9. PMID: 26828195; PMCID: PMC4900892.
  4. Haradhvala NJ, Polak P, Stojanov P, Covington KR, Shinbrot E, Hess JM, Rheinbay E, Kim J, Maruvka YE, Braunstein LZ, Kamburov A, Hanawalt PC, Wheeler DA, Koren A, Lawrence MS, Getz G. Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair. Cell. 2016 Jan 28; 164(3):538-49. PMID: 26806129; PMCID: PMC4753048 [Available on 01/28/17].
  5. Selmecki AM, Maruvka YE, Richmond PA, Guillet M, Shoresh N, Sorenson AL, De S, Kishony R, Michor F, Dowell R, Pellman D. Polyploidy can drive rapid adaptation in yeast. Nature. 2015 Mar 19; 519(7543):349-52. PMID: 25731168; PMCID: PMC4497379.
  6. Maruvka YE, Tang M, Michor F. On the validity of using increases in 5-year survival rates to measure success in the fight against cancer. PLoS One. 2014; 9(7):e83100. PMID: 25054541; PMCID: PMC4108307.
  7. Chapal-Ilani N, Maruvka YE, Spiro A, Reizel Y, Adar R, Shlush LI, Shapiro E. Comparing algorithms that reconstruct cell lineage trees utilizing information on microsatellite mutations. PLoS Comput Biol. 2013; 9(11):e1003297. PMID: 24244121; PMCID: PMC3828138.
  8. Maruvka YE, Shnerb NM. First principles theories for last name dynamics. Phys Life Rev. 2013 Dec; 10(4):422-3; discussion 426-7. PMID: 23973008.
    View in: PubMed
  9. Haeno H, Maruvka YE, Iwasa Y, Michor F. Stochastic Tunneling of Two Mutations in a Population of Cancer Cells. PLoS One. 2013; 8(6):e65724. PMID: 23840359; PMCID: PMC3694076.
  10. Maruvka YE, Shnerb NM, Kessler DA, Ricklefs RE. Model for macroevolutionary dynamics. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):E2460-9. PMID: 23781101; PMCID: PMC3703965.
  11. Ohashi K, Maruvka YE, Michor F, Pao W. Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease. J Clin Oncol. 2013 Mar 10; 31(8):1070-80. PMID: 23401451; PMCID: PMC3589701.
  12. Seri E, Maruvka YE, Shnerb NM. Neutral dynamics and cluster statistics in a tropical forest. Am Nat. 2012 Dec; 180(6):E161-73. PMID: 23149409.
    View in: PubMed
  13. Shlush LI, Chapal-Ilani N, Adar R, Pery N, Maruvka Y, Spiro A, Shouval R, Rowe JM, Tzukerman M, Bercovich D, Izraeli S, Marcucci G, Bloomfield CD, Zuckerman T, Skorecki K, Shapiro E. Cell lineage analysis of acute leukemia relapse uncovers the role of replication-rate heterogeneity and microsatellite instability. Blood. 2012 Jul 19; 120(3):603-12. PMID: 22645183.
    View in: PubMed
  14. Reizel Y, Itzkovitz S, Adar R, Elbaz J, Jinich A, Chapal-Ilani N, Maruvka YE, Nevo N, Marx Z, Horovitz I, Wasserstrom A, Mayo A, Shur I, Benayahu D, Skorecki K, Segal E, Dekel N, Shapiro E. Cell lineage analysis of the mammalian female germline. PLoS Genet. 2012; 8(2):e1002477. PMID: 22383887; PMCID: PMC3285577.
  15. Maruvka YE, Kessler DA, Shnerb NM. The birth-death-mutation process: a new paradigm for fat tailed distributions. PLoS One. 2011; 6(11):e26480. PMID: 22069453; PMCID: PMC3206027.
  16. Reizel Y, Chapal-Ilani N, Adar R, Itzkovitz S, Elbaz J, Maruvka YE, Segev E, Shlush LI, Dekel N, Shapiro E. Colon stem cell and crypt dynamics exposed by cell lineage reconstruction. PLoS Genet. 2011 Jul; 7(7):e1002192. PMID: 21829376; PMCID: PMC3145618.
  17. Maruvka YE, Shnerb NM, Bar-Yam Y, Wakeley J. Recovering population parameters from a single gene genealogy: an unbiased estimator of the growth rate. Mol Biol Evol. 2011 May; 28(5):1617-31. PMID: 21172828.
    View in: PubMed
  18. Maruvka YE, Shnerb NM. Polymorphism data can reveal the origin of species abundance statistics. PLoS Comput Biol. 2009 Apr; 5(4):e1000359. PMID: 19390605; PMCID: PMC2667257.
  19. Maruvka YE, Kalisky T, Shnerb NM. Nonlocal competition and the speciation transition on random networks. Phys Rev E Stat Nonlin Soft Matter Phys. 2008 Sep; 78(3 Pt 1):031920. PMID: 18851078.
    View in: PubMed
  20. Maruvka YE, Shnerb NM. Nonlocal competition and front propagation in branching-coalescence systems. Phys Rev E Stat Nonlin Soft Matter Phys. 2007 Apr; 75(4 Pt 1):042901. PMID: 17500943.
    View in: PubMed
  21. Maruvka YE, Shnerb NM. Nonlocal competition and logistic growth: patterns, defects, and fronts. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Jan; 73(1 Pt 1):011903. PMID: 16486181.
    View in: PubMed
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