Contact, publication, and social network information about Harvard faculty and fellows. Harvard Catalyst Profiles
Check out the new look and feel of Harvard Catalyst Profiles! Learn more on our About and Help pages.

Davide Cacchiarelli, Ph.D., Ph.D.

Title
Institution
Department
Address

Biography
2007 - 2011
Microsoft Research PhD Scholarship
2012 - 2015
Human Frontier Science Program Fellow

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
List All   |   Timeline
  1. Nehme R, Zuccaro E, Ghosh SD, Li C, Sherwood JL, Pietilainen O, Barrett LE, Limone F, Worringer KA, Kommineni S, Zang Y, Cacchiarelli D, Meissner A, Adolfsson R, Haggarty S, Madison J, Muller M, Arlotta P, Fu Z, Feng G, Eggan K. Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission. Cell Rep. 2018 May 22; 23(8):2509-2523. PMID: 29791859.
    View in: PubMed
  2. Cesana M, Guo MH, Cacchiarelli D, Wahlster L, Barragan J, Doulatov S, Vo LT, Salvatori B, Trapnell C, Clement K, Cahan P, Tsanov KM, Sousa PM, Tazon-Vega B, Bolondi A, Giorgi FM, Califano A, Rinn JL, Meissner A, Hirschhorn JN, Daley GQ. A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development. Cell Stem Cell. 2018 Apr 05; 22(4):575-588.e7. PMID: 29625070.
    View in: PubMed
  3. Galonska C, Charlton J, Mattei AL, Donaghey J, Clement K, Gu H, Mohammad AW, Stamenova EK, Cacchiarelli D, Klages S, Timmermann B, Cantz T, Schöler HR, Gnirke A, Ziller MJ, Meissner A. Genome-wide tracking of dCas9-methyltransferase footprints. Nat Commun. 2018 02 09; 9(1):597. PMID: 29426832.
    View in: PubMed
  4. Donaghey J, Thakurela S, Charlton J, Chen JS, Smith ZD, Gu H, Pop R, Clement K, Stamenova EK, Karnik R, Kelley DR, Gifford CA, Cacchiarelli D, Rinn JL, Gnirke A, Ziller MJ, Meissner A. Genetic determinants and epigenetic effects of pioneer-factor occupancy. Nat Genet. 2018 Feb; 50(2):250-258. PMID: 29358654.
    View in: PubMed
  5. Maddalena A, Tornabene P, Tiberi P, Minopoli R, Manfredi A, Mutarelli M, Rossi S, Simonelli F, Naggert JK, Cacchiarelli D, Auricchio A. Triple Vectors Expand AAV Transfer Capacity in the Retina. Mol Ther. 2018 Feb 07; 26(2):524-541. PMID: 29292161.
    View in: PubMed
  6. Smith ZD, Shi J, Gu H, Donaghey J, Clement K, Cacchiarelli D, Gnirke A, Michor F, Meissner A. Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer. Nature. 2017 09 28; 549(7673):543-547. PMID: 28959968.
    View in: PubMed
  7. Aguilar CA, Pop R, Shcherbina A, Watts A, Matheny RW, Cacchiarelli D, Han WM, Shin E, Nakhai SA, Jang YC, Carrigan CT, Gifford CA, Kottke MA, Cesana M, Lee J, Urso ML, Meissner A. Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma. Stem Cell Reports. 2016 11 08; 7(5):983-997. PMID: 27773702.
    View in: PubMed
  8. Brenan L, Andreev A, Cohen O, Pantel S, Kamburov A, Cacchiarelli D, Persky NS, Zhu C, Bagul M, Goetz EM, Burgin AB, Garraway LA, Getz G, Mikkelsen TS, Piccioni F, Root DE, Johannessen CM. Phenotypic Characterization of a Comprehensive Set of MAPK1/ERK2 Missense Mutants. Cell Rep. 2016 10 18; 17(4):1171-1183. PMID: 27760319.
    View in: PubMed
  9. Zhang J, Ratanasirintrawoot S, Chandrasekaran S, Wu Z, Ficarro SB, Yu C, Ross CA, Cacchiarelli D, Xia Q, Seligson M, Shinoda G, Xie W, Cahan P, Wang L, Ng SC, Tintara S, Trapnell C, Onder T, Loh YH, Mikkelsen T, Sliz P, Teitell MA, Asara JM, Marto JA, Li H, Collins JJ, Daley GQ. LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. Cell Stem Cell. 2016 07 07; 19(1):66-80. PMID: 27320042.
    View in: PubMed
  10. Cacchiarelli D, Trapnell C, Ziller MJ, Soumillon M, Cesana M, Karnik R, Donaghey J, Smith ZD, Ratanasirintrawoot S, Zhang X, Ho Sui SJ, Wu Z, Akopian V, Gifford CA, Doench J, Rinn JL, Daley GQ, Meissner A, Lander ES, Mikkelsen TS. Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced Pluripotency. Cell. 2015 Jul 16; 162(2):412-424. PMID: 26186193; PMCID: PMC4511597.
  11. Ziller MJ, Edri R, Yaffe Y, Donaghey J, Pop R, Mallard W, Issner R, Gifford CA, Goren A, Xing J, Gu H, Cachiarelli D, Tsankov A, Epstein C, Rinn JR, Mikkelsen TS, Kohlbacher O, Gnirke A, Bernstein BE, Elkabetz Y, Meissner A. Dissecting neural differentiation regulatory networks through epigenetic footprinting. Nature. 2015 Feb 19; 518(7539):355-359. PMID: 25533951; PMCID: PMC4336237.
  12. Schwartz S, Mumbach MR, Jovanovic M, Wang T, Maciag K, Bushkin GG, Mertins P, Ter-Ovanesyan D, Habib N, Cacchiarelli D, Sanjana NE, Freinkman E, Pacold ME, Satija R, Mikkelsen TS, Hacohen N, Zhang F, Carr SA, Lander ES, Regev A. Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10; 8(1):284-96. PMID: 24981863; PMCID: PMC4142486.
  13. Herlofsen SR, Høiby T, Cacchiarelli D, Zhang X, Mikkelsen TS, Brinchmann JE. Brief report: importance of SOX8 for in vitro chondrogenic differentiation of human mesenchymal stromal cells. Stem Cells. 2014 Jun; 32(6):1629-35. PMID: 24449344.
    View in: PubMed
  14. Trapnell C, Cacchiarelli D, Grimsby J, Pokharel P, Li S, Morse M, Lennon NJ, Livak KJ, Mikkelsen TS, Rinn JL. The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells. Nat Biotechnol. 2014 Apr; 32(4):381-386. PMID: 24658644; PMCID: PMC4122333.
  15. Twayana S, Legnini I, Cesana M, Cacchiarelli D, Morlando M, Bozzoni I. Biogenesis and function of non-coding RNAs in muscle differentiation and in Duchenne muscular dystrophy. Biochem Soc Trans. 2013 Aug; 41(4):844-9. PMID: 23863142.
    View in: PubMed
  16. Cesana M, Cacchiarelli D, Legnini I, Santini T, Sthandier O, Chinappi M, Tramontano A, Bozzoni I. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell. 2011 Oct 14; 147(2):358-69. PMID: 22000014; PMCID: PMC3234495.
  17. Cacchiarelli D, Legnini I, Martone J, Cazzella V, D'Amico A, Bertini E, Bozzoni I. miRNAs as serum biomarkers for Duchenne muscular dystrophy. EMBO Mol Med. 2011 May; 3(5):258-65. PMID: 21425469; PMCID: PMC3112257.
  18. Cacchiarelli D, Incitti T, Martone J, Cesana M, Cazzella V, Santini T, Sthandier O, Bozzoni I. miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy. EMBO Rep. 2011 Feb; 12(2):136-41. PMID: 21212803; PMCID: PMC3049433.
  19. Cacchiarelli D, Martone J, Girardi E, Cesana M, Incitti T, Morlando M, Nicoletti C, Santini T, Sthandier O, Barberi L, Auricchio A, Musarò A, Bozzoni I. MicroRNAs involved in molecular circuitries relevant for the Duchenne muscular dystrophy pathogenesis are controlled by the dystrophin/nNOS pathway. Cell Metab. 2010 Oct 06; 12(4):341-51. PMID: 20727829.
    View in: PubMed
  20. Ballarino M, Pagano F, Girardi E, Morlando M, Cacchiarelli D, Marchioni M, Proudfoot NJ, Bozzoni I. Coupled RNA processing and transcription of intergenic primary microRNAs. Mol Cell Biol. 2009 Oct; 29(20):5632-8. PMID: 19667074; PMCID: PMC2756881.
  21. Cacchiarelli D, Santoni D, Bozzoni I. MicroRNAs as prime players in a combinatorial view of evolution. RNA Biol. 2008 Jul-Sep; 5(3):120-122. PMID: 18698151.
    View in: PubMed
  22. Pavoni E, Cacchiarelli D, Tittarelli R, Orsini M, Galtieri A, Giardina B, Brancaccio A. Duplication of the dystroglycan gene in most branches of teleost fish. BMC Mol Biol. 2007 May 17; 8:34. PMID: 17509131; PMCID: PMC1885269.
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: FAS faculty should contact the Office for Scholarly Communication (oschulmail.harvard.edu) for general questions about Profiles. For data questions, please contact Raelyn Lincoln (raelyn_lincolnharvard.edu) from the FAS Division of Science; Jennifer Shephard (jmshephfas.harvard.edu) from the FAS Division of Social Science; or Alexander Parker (afparkerfas.harvard.edu) from the FAS Division of Arts and Humanities.
Cacchiarelli's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (111)
Explore
_
Co-Authors (32)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_