Harvard Catalyst Profiles

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Max Friesen, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Schulman S, El-Darzi E, Florido MH, Friesen M, Merrill-Skoloff G, Brake MA, Schuster CR, Lin L, Westrick RJ, Cowan CA, Flaumenhaft R, BioResource N, Ouwehand WH, Peerlinck K, Freson K, Turro E, Furie B. A coagulation defect arising from heterozygous premature termination of tissue factor. J Clin Invest. 2020 Jul 14. PMID: 32663190.
    Citations:    
  2. Toyohara T, Roudnicky F, Florido MHC, Nakano T, Yu H, Katsuki S, Lee M, Meissner T, Friesen M, Davidow LS, Ptaszek L, Abe T, Rubin LL, Pereira AC, Aikawa M, Cowan CA. Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis. Cell Stem Cell. 2020 Jul 02; 27(1):178-180. PMID: 32619513.
    Citations:    
  3. Toyohara T, Roudnicky F, Florido MHC, Nakano T, Yu H, Katsuki S, Lee M, Meissner T, Friesen M, Davidow LS, Ptaszek L, Abe T, Rubin LL, Pereira AC, Aikawa M, Cowan CA. Patient hiPSCs Identify Vascular Smooth Muscle Arylacetamide Deacetylase as Protective against Atherosclerosis. Cell Stem Cell. 2020 Jul 02; 27(1):147-157.e7. PMID: 32413331.
    Citations:    
  4. Friesen M, Warren CR, Yu H, Toyohara T, Ding Q, Florido MHC, Sayre C, Pope BD, Goff LA, Rinn JL, Cowan CA. Mitoregulin Controls ß-Oxidation in Human and Mouse Adipocytes. Stem Cell Reports. 2020 04 14; 14(4):590-602. PMID: 32243843.
    Citations:    
  5. Roudnicky F, Lan Y, Friesen M, Dernick G, Zhang JD, Staempfli A, Bordag N, Wagner-Golbs A, Christensen K, Ebeling M, Graf M, Burcin M, Meyer CA, Cowan CA, Patsch C. Modeling the Effects of Severe Metabolic Disease by Genome Editing of hPSC-Derived Endothelial Cells Reveals an Inflammatory Phenotype. Int J Mol Sci. 2019 Dec 09; 20(24). PMID: 31835296.
    Citations:    
  6. Chen Z, Yu H, Shi X, Warren CR, Lotta LA, Friesen M, Meissner TB, Langenberg C, Wabitsch M, Wareham N, Benson MD, Gerszten RE, Cowan CA. Functional Screening of Candidate Causal Genes for Insulin Resistance in Human Preadipocytes and Adipocytes. Circ Res. 2020 01 31; 126(3):330-346. PMID: 31739742.
    Citations:    
  7. Friesen M, Cowan CA. Adipocyte Metabolism and Insulin Signaling Perturbations: Insights from Genetics. Trends Endocrinol Metab. 2019 06; 30(6):396-406. PMID: 31072658.
    Citations:    
  8. Friesen M, Cowan CA. FPLD2 LMNA mutation R482W dysregulates iPSC-derived adipocyte function and lipid metabolism. Biochem Biophys Res Commun. 2018 01 01; 495(1):254-260. PMID: 29108996.
    Citations: 2     Fields:    Translation:HumansCells
  9. Friesen M, Camahort R, Lee YK, Xia F, Gerszten RE, Rhee EP, Deo RC, Cowan CA. Activation of IRF1 in Human Adipocytes Leads to Phenotypes Associated with Metabolic Disease. Stem Cell Reports. 2017 05 09; 8(5):1164-1173. PMID: 28416283.
    Citations:    Fields:    Translation:HumansAnimalsCells
  10. Warren CR, O'Sullivan JF, Friesen M, Becker CE, Zhang X, Liu P, Wakabayashi Y, Morningstar JE, Shi X, Choi J, Xia F, Peters DT, Florido MHC, Tsankov AM, Duberow E, Comisar L, Shay J, Jiang X, Meissner A, Musunuru K, Kathiresan S, Daheron L, Zhu J, Gerszten RE, Deo RC, Vasan RS, O'Donnell CJ, Cowan CA. Induced Pluripotent Stem Cell Differentiation Enables Functional Validation of GWAS Variants in Metabolic Disease. Cell Stem Cell. 2017 04 06; 20(4):547-557.e7. PMID: 28388431.
    Citations: 9     Fields:    Translation:HumansCells
  11. Friesen M, Hudak CS, Warren CR, Xia F, Cowan CA. Adipocyte insulin receptor activity maintains adipose tissue mass and lifespan. Biochem Biophys Res Commun. 2016 08 05; 476(4):487-492. PMID: 27246738.
    Citations: 1     Fields:    Translation:AnimalsCells
  12. Peters DT, Henderson CA, Warren CR, Friesen M, Xia F, Becker CE, Musunuru K, Cowan CA. Asialoglycoprotein receptor 1 is a specific cell-surface marker for isolating hepatocytes derived from human pluripotent stem cells. Development. 2016 05 01; 143(9):1475-81. PMID: 27143754.
    Citations: 2     Fields:    Translation:HumansCells
  13. Mandal PK, Ferreira LM, Collins R, Meissner TB, Boutwell CL, Friesen M, Vrbanac V, Garrison BS, Stortchevoi A, Bryder D, Musunuru K, Brand H, Tager AM, Allen TM, Talkowski ME, Rossi DJ, Cowan CA. Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9. Cell Stem Cell. 2014 Nov 06; 15(5):643-52. PMID: 25517468.
    Citations: 104     Fields:    Translation:HumansAnimalsCells
  14. Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, Schinzel RT, Xia F, Tang A, Xia Y, Figueroa E, Wann A, Ahfeldt T, Daheron L, Zhang F, Rubin LL, Peng LF, Chung RT, Musunuru K, Cowan CA. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 2013 Feb 07; 12(2):238-51. PMID: 23246482.
    Citations: 187     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.