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Peggy Sue Lai, M.D.

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Biography
Harvard School of Public Health, Boston, MAMPH05/2013Quantitative Methods

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AI144119 (LAI, PEGGY SUE) Jan 1, 2019 - Dec 31, 2023
    NIH/NIAID
    The school microbiome and asthma morbidity in inner-city children
    Role: Principal Investigator
  2. K23ES023700 (LAI, PEGGY SUE) Sep 23, 2013 - May 31, 2018
    NIH/NIEHS
    Endotoxin, the airway transcriptome, and obstructive lung disease
    Role: Principal Investigator
  3. F32ES020082 (LAI, PEGGY SUE) Apr 15, 2012 - May 31, 2013
    NIH/NIEHS
    Lung disease due to chronic endotoxin exposure in mouse and human models
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Lai PS, Christiani DC. Impact of occupational exposure on human microbiota. Curr Opin Allergy Clin Immunol. 2019 Apr; 19(2):86-91. PMID: 30507717.
    Citations:    Fields:    
  2. Baxi SN, Sheehan WJ, Sordillo JE, Muilenberg ML, Rogers CA, Gaffin JM, Permaul P, Lai PS, Louisias M, Petty CR, Fu C, Gold DR, Phipatanakul W. Association between fungal spore exposure in inner-city schools and asthma morbidity. Ann Allergy Asthma Immunol. 2019 Jun; 122(6):610-615.e1. PMID: 30904580.
    Citations:    
  3. Louisias M, Petty CR, Sheehan W, Lai P, Phipatanakul W. Use of a School-Based Survey to Screen Students for Symptoms Concerning for Asthma. Clin Pediatr (Phila). 2019 May; 58(5):586-589. PMID: 30829046.
    Citations:    
  4. Lai PS, Bebell LM, Meney C, Valeri L, White MC. Epidemiology of antibiotic-resistant wound infections from six countries in Africa. BMJ Glob Health. 2017; 2(Suppl 4):e000475. PMID: 29588863.
    Citations: 1     
  5. Lai PS, Kolde R, Franzosa EA, Gaffin JM, Baxi SN, Sheehan WJ, Gold DR, Gevers D, Xavier RJ, Phipatanakul W. The classroom microbiome and asthma morbidity in children attending 3 inner-city schools. J Allergy Clin Immunol. 2018 Jun; 141(6):2311-2313. PMID: 29518428.
    Citations:    Fields:    
  6. Gaffin JM, Hauptman M, Petty CR, Sheehan WJ, Lai PS, Wolfson JM, Gold DR, Coull BA, Koutrakis P, Phipatanakul W. Nitrogen dioxide exposure in school classrooms of inner-city children with asthma. J Allergy Clin Immunol. 2018 Jun; 141(6):2249-2255.e2. PMID: 28988796.
    Citations: 1     Fields:    
  7. Lai PS, Massoud AH, Xia M, Petty CR, Cunningham A, Chatila TA, Phipatanakul W. Gene-environment interaction between an IL4R variant and school endotoxin exposure contributes to asthma symptoms in inner-city children. J Allergy Clin Immunol. 2018 Feb; 141(2):794-796.e3. PMID: 28943468.
    Citations:    Fields:    
  8. Lai PS, Allen JG, Hutchinson DS, Ajami NJ, Petrosino JF, Winters T, Hug C, Wartenberg GR, Vallarino J, Christiani DC. Impact of environmental microbiota on human microbiota of workers in academic mouse research facilities: An observational study. PLoS One. 2017; 12(7):e0180969. PMID: 28704437.
    Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  9. Jhun I, Lai PS, Phipatanakul W. Reply. J Allergy Clin Immunol Pract. 2017 Jul - Aug; 5(4):1165-1166. PMID: 28689836.
    Citations:    Fields:    
  10. Phipatanakul W, Koutrakis P, Coull BA, Kang CM, Wolfson JM, Ferguson ST, Petty CR, Samnaliev M, Cunningham A, Sheehan WJ, Gaffin JM, Baxi SN, Lai PS, Permaul P, Liang L, Thorne PS, Adamkiewicz G, Brennan KJ, Baccarelli AA, Gold DR. The School Inner-City Asthma Intervention Study: Design, rationale, methods, and lessons learned. Contemp Clin Trials. 2017 09; 60:14-23. PMID: 28619649.
    Citations: 2     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  11. Muyanja D, Allen JG, Vallarino J, Valeri L, Kakuhikire B, Bangsberg DR, Christiani DC, Tsai AC, Lai PS. Kerosene lighting contributes to household air pollution in rural Uganda. Indoor Air. 2017 09; 27(5):1022-1029. PMID: 28267233.
    Citations:    Fields:    Translation:HumansPHPublic Health
  12. White MC, Longstaff L, Lai PS. Effect of Pre-operative Anaemia on Post-operative Complications in Low-Resource Settings. World J Surg. 2017 Mar; 41(3):644-649. PMID: 27837236.
    Citations: 1     Fields:    Translation:Humans
  13. Sheehan WJ, Permaul P, Petty CR, Coull BA, Baxi SN, Gaffin JM, Lai PS, Gold DR, Phipatanakul W. Association Between Allergen Exposure in Inner-City Schools and Asthma Morbidity Among Students. JAMA Pediatr. 2017 01 01; 171(1):31-38. PMID: 27893060.
    Citations: 6     Fields:    Translation:HumansAnimalsPHPublic Health
  14. White MC, Horner KC, Lai PS. Retrospective Review of the Anaesthetic Management of Maxillectomies and Mandibulectomies for Benign Tumours in Sub-Saharan Africa. PLoS One. 2016; 11(10):e0165090. PMID: 27788172.
    Citations:    Fields:    Translation:Humans
  15. Jhun I, Gaffin JM, Coull BA, Huffaker MF, Petty CR, Sheehan WJ, Baxi SN, Lai PS, Kang CM, Wolfson JM, Gold DR, Koutrakis P, Phipatanakul W. School Environmental Intervention to Reduce Particulate Pollutant Exposures for Children with Asthma. J Allergy Clin Immunol Pract. 2017 Jan - Feb; 5(1):154-159.e3. PMID: 27641483.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  16. Gaffin JM, Petty CR, Hauptman M, Kang CM, Wolfson JM, Abu Awad Y, Di Q, Lai PS, Sheehan WJ, Baxi S, Coull BA, Schwartz JD, Gold DR, Koutrakis P, Phipatanakul W. Modeling indoor particulate exposures in inner-city school classrooms. J Expo Sci Environ Epidemiol. 2017 09; 27(5):451-457. PMID: 27599884.
    Citations: 2     Fields:    Translation:PHPublic Health
  17. Lai PS, Hang JQ, Zhang FY, Sun J, Zheng BY, Su L, Washko GR, Christiani DC. Imaging Phenotype of Occupational Endotoxin-Related Lung Function Decline. Environ Health Perspect. 2016 09; 124(9):1436-42. PMID: 27138294.
    Citations:    Fields:    Translation:HumansPHPublic Health
  18. Shrime MG, Ferket BS, Scott DJ, Lee J, Barragan-Bradford D, Pollard T, Arabi YM, Al-Dorzi HM, Baron RM, Hunink MG, Celi LA, Lai PS. Time-Limited Trials of Intensive Care for Critically Ill Patients With Cancer: How Long Is Long Enough? JAMA Oncol. 2016 Jan; 2(1):76-83. PMID: 26469222.
    Citations: 5     Fields:    Translation:Humans
  19. Shenoy ES, Lai PS, Shepard JA, Kradin RL. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 39-2015. A 22-Year-Old Man with Hypoxemia and Shock. N Engl J Med. 2015 Dec 17; 373(25):2456-66. PMID: 26672848.
    Citations: 1     Fields:    Translation:HumansCells
  20. Lai PS, Sheehan WJ, Gaffin JM, Petty CR, Coull BA, Gold DR, Phipatanakul W. School Endotoxin Exposure and Asthma Morbidity in Inner-city Children. Chest. 2015 Nov; 148(5):1251-1258. PMID: 26087201.
    Citations: 5     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  21. Lai PS, Liang L, Cibas ES, Liu AH, Gold DR, Baccarelli A, Phipatanakul W. Alternate methods of nasal epithelial cell sampling for airway genomic studies. J Allergy Clin Immunol. 2015 Oct; 136(4):1120-3.e4. PMID: 26037550.
    Citations: 2     Fields:    Translation:HumansCells
  22. Lai PS, Hang JQ, Valeri L, Zhang FY, Zheng BY, Mehta AJ, Shi J, Su L, Brown D, Eisen EA, Christiani DC. Endotoxin and gender modify lung function recovery after occupational organic dust exposure: a 30-year study. Occup Environ Med. 2015 Aug; 72(8):546-552. PMID: 25666844.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  23. Lai P, Hang JQ, Zhang FY, Zheng BY, Valeri L, Eisen E, Christiani D. 0031 Lung Function Improvement is Sustained after Work Cessation in Shanghai Cotton and Silk Textile Workers. Occup Environ Med. 2014 Jun; 71 Suppl 1:A3. PMID: 25018313.
    Citations:    
  24. Lai PS, Hang JQ, Zhang FY, Lin X, Zheng BY, Dai HL, Su L, Cai T, Christiani DC. Gender differences in the effect of occupational endotoxin exposure on impaired lung function and death: the Shanghai Textile Worker Study. Occup Environ Med. 2014 Feb; 71(2):118-125. PMID: 24297825.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  25. Baxi SN, Muilenberg ML, Rogers CA, Sheehan WJ, Gaffin J, Permaul P, Kopel LS, Lai PS, Lane JP, Bailey A, Petty CR, Fu C, Gold DR, Phipatanakul W. Exposures to molds in school classrooms of children with asthma. Pediatr Allergy Immunol. 2013 Nov; 24(7):697-703. PMID: 24112429.
    Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  26. Lai PS, Mita C, Thompson BT. What is the clinical significance of pulmonary hypertension in acute respiratory distress syndrome? A review. Minerva Anestesiol. 2014 May; 80(5):574-85. PMID: 24193181.
    Citations:    Fields:    Translation:Humans
  27. Lai PS, Thompson BT. Why activated protein C was not successful in severe sepsis and septic shock: are we still tilting at windmills? Curr Infect Dis Rep. 2013 Oct; 15(5):407-12. PMID: 23925482.
    Citations: 2     
  28. Lai PS, Hofmann O, Baron RM, Cernadas M, Meng QR, Bresler HS, Brass DM, Yang IV, Schwartz DA, Christiani DC, Hide W. Integrating murine gene expression studies to understand obstructive lung disease due to chronic inhaled endotoxin. PLoS One. 2013; 8(5):e62910. PMID: 23675439.
    Citations:    Fields:    Translation:AnimalsCells
  29. Mayaud L, Lai PS, Clifford GD, Tarassenko L, Celi LA, Annane D. Dynamic data during hypotensive episode improves mortality predictions among patients with sepsis and hypotension. Crit Care Med. 2013 Apr; 41(4):954-62. PMID: 23385106.
    Citations: 16     Fields:    Translation:Humans
  30. Lai PS, Christiani DC. Long-term respiratory health effects in textile workers. Curr Opin Pulm Med. 2013 Mar; 19(2):152-7. PMID: 23361196.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  31. Lai PS, Matteau A, Iddriss A, Hawes JC, Ranieri V, Thompson BT. An updated meta-analysis to understand the variable efficacy of drotrecogin alfa (activated) in severe sepsis and septic shock. Minerva Anestesiol. 2013 Jan; 79(1):33-43. PMID: 23174922.
    Citations: 5     Fields:    Translation:Humans
  32. Lai PS, Fresco JM, Pinilla MA, Macias AA, Brown RD, Englert JA, Hofmann O, Lederer JA, Hide W, Christiani DC, Cernadas M, Baron RM. Chronic endotoxin exposure produces airflow obstruction and lung dendritic cell expansion. Am J Respir Cell Mol Biol. 2012 Aug; 47(2):209-17. PMID: 22517795.
    Citations: 8     Fields:    Translation:AnimalsCellsPHPublic Health
  33. Lai PS, Cohen DW, DeCamp MM, Fazio S, Roberts DH. A 40-year-old woman with an asymptomatic cystic lesion in her right lung. Chest. 2009 Aug; 136(2):622-627. PMID: 19666763.
    Citations: 1     Fields:    Translation:Humans
  34. Ruan B, Lai PS, Yeh CW, Wilson WK, Pang J, Xu R, Matsuda SP, Schroepfer GJ. Alternative pathways of sterol synthesis in yeast. Use of C(27) sterol tracers to study aberrant double-bond migrations and evaluate their relative importance. Steroids. 2002 Dec; 67(13-14):1109-19. PMID: 12441197.
    Citations: 2     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.