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Manoj K Gupta, Ph.D.

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Biography
2009
Best Poster presentation award in 5th international NRW meeting on stem cell research in Germany
2010
ISSCR travel grant award
2010
Ist Best Poster award in 5th Annual GSZ meeting, Germany
2014
Seahorse Bioscience Travel grant award
2017 - 2020
JDRF Advanced Postdoctoral Fellowship Award

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gupta MK, Vadde R. Identification and characterization of differentially expressed genes in Type 2 Diabetes using in silico approach. Comput Biol Chem. 2019 Jan 24; 79:24-35. PMID: 30708140.
    Citations:    Fields:    
  2. Gupta MK, Vadde R. Insights into the structure-function relationship of both wild and mutant zinc transporter ZnT8 in human: a computational structural biology approach. J Biomol Struct Dyn. 2019 Jan 11; 1-15. PMID: 30633652.
    Citations:    Fields:    
  3. Gavali S, Gupta MK, Daswani B, Wani MR, Sirdeshmukh R, Khatkhatay MI. LYN, a key mediator in estrogen-dependent suppression of osteoclast differentiation, survival, and function. Biochim Biophys Acta Mol Basis Dis. 2019 Mar 01; 1865(3):547-557. PMID: 30579930.
    Citations:    
  4. Gupta MK, Vadde R. In silico identification of natural product inhibitors for ?-secretase activating protein, a therapeutic target for Alzheimer's disease. J Cell Biochem. 2018 Dec 19. PMID: 30565717.
    Citations:    Fields:    
  5. Rao TN, Gupta MK, Softic S, Wang LD, Jang YC, Thomou T, Bezy O, Kulkarni RN, Kahn CR, Wagers AJ. Attenuation of PKCd enhances metabolic activity and promotes expansion of blood progenitors. EMBO J. 2018 Dec 14; 37(24). PMID: 30446598.
    Citations:    Fields:    
  6. Gupta MK, De Jesus DF, Kahraman S, Valdez IA, Shamsi F, Yi L, Swensen AC, Tseng YH, Qian WJ, Kulkarni RN. Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation. Mol Metab. 2018 Dec; 18:153-163. PMID: 30316806.
    Citations:    Fields:    
  7. Softic S, Gupta MK, Wang GX, Fujisaka S, O'Neill BT, Rao TN, Willoughby J, Harbison C, Fitzgerald K, Ilkayeva O, Newgard CB, Cohen DE, Kahn CR. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2017 Nov 01; 127(11):4059-4074. PMID: 28972537.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  8. Valdez IA, Dirice E, Gupta MK, Shirakawa J, Teo AKK, Kulkarni RN. Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation. Cell Rep. 2016 Apr 19; 15(3):460-470. PMID: 27068459; PMCID: PMC4838491.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  9. Gupta MK, Ajay AK. Fat on sale: role of adipose-derived stem cells as anti-fibrosis agent in regenerative medicine. Stem Cell Res Ther. 2015 Dec 01; 6:233. PMID: 26620570; PMCID: PMC4666015.
    Citations: 1     Fields:    Translation:AnimalsCells
  10. Gupta MK, Teo AK, Rao TN, Bhatt S, Kleinridders A, Shirakawa J, Takatani T, Hu J, De Jesus DF, Windmueller R, Wagers AJ, Kulkarni RN. Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts. Stem Cells Transl Med. 2015 Oct; 4(10):1101-8. PMID: 26253715; PMCID: PMC4572895.
    Citations: 3     Fields:    Translation:HumansCells
  11. Bhatt S, Gupta MK, Khamaisi M, Martinez R, Gritsenko MA, Wagner BK, Guye P, Busskamp V, Shirakawa J, Wu G, Liew CW, Clauss TR, Valdez I, El Ouaamari A, Dirice E, Takatani T, Keenan HA, Smith RD, Church G, Weiss R, Wagers AJ, Qian WJ, King GL, Kulkarni RN. Preserved DNA Damage Checkpoint Pathway Protects against Complications in Long-Standing Type 1 Diabetes. Cell Metab. 2015 Aug 04; 22(2):239-52. PMID: 26244933; PMCID: PMC4589213.
    Citations: 9     Fields:    Translation:HumansCells
  12. Teo AK, Gupta MK, Doria A, Kulkarni RN. Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools. Mol Metab. 2015 Sep; 4(9):593-604. PMID: 26413465.
    Citations: 2     Fields:    
  13. Rao TN, Marks-Bluth J, Sullivan J, Gupta MK, Chandrakanthan V, Fitch SR, Ottersbach K, Jang YC, Piao X, Kulkarni RN, Serwold T, Pimanda JE, Wagers AJ. High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice. Stem Cell Res. 2015 May; 14(3):307-22. PMID: 25840412; PMCID: PMC4439311.
    Citations: 3     Fields:    Translation:AnimalsCells
  14. Gupta MK, Rao TN. Hearty miR-363 controls HAND1 in cardiac cell specification. Stem Cell Res Ther. 2014 Jul 29; 5(4):89. PMID: 25157599; PMCID: PMC4282149.
    Citations:    Fields:    Translation:HumansCells
  15. Fatima A, Kaifeng S, Dittmann S, Xu G, Gupta MK, Linke M, Zechner U, Nguemo F, Milting H, Farr M, Hescheler J, Saric T. The disease-specific phenotype in cardiomyocytes derived from induced pluripotent stem cells of two long QT syndrome type 3 patients. PLoS One. 2013; 8(12):e83005. PMID: 24349418; PMCID: PMC3859612.
    Citations: 20     Fields:    Translation:HumansCellsCTClinical Trials
  16. Nguemo F, Fleischmann BK, Gupta MK, Saric T, Malan D, Liang H, Pfannkuche K, Bloch W, Schunkert H, Hescheler J, Reppel M. The L-type Ca2+ channels blocker nifedipine represses mesodermal fate determination in murine embryonic stem cells. PLoS One. 2013; 8(1):e53407. PMID: 23320083; PMCID: PMC3539992.
    Citations: 5     Fields:    Translation:AnimalsCells
  17. Shao K, Koch C, Gupta MK, Lin Q, Lenz M, Laufs S, Denecke B, Schmidt M, Linke M, Hennies HC, Hescheler J, Zenke M, Zechner U, Šaric T, Wagner W. Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles. Mol Ther. 2013 Jan; 21(1):240-50. PMID: 23032973; PMCID: PMC3538313.
    Citations: 22     Fields:    Translation:HumansCells
  18. Gupta MK, Illich DJ, Gaarz A, Matzkies M, Nguemo F, Pfannkuche K, Liang H, Classen S, Reppel M, Schultze JL, Hescheler J, Saric T. Global transcriptional profiles of beating clusters derived from human induced pluripotent stem cells and embryonic stem cells are highly similar. BMC Dev Biol. 2010 Sep 15; 10:98. PMID: 20843318; PMCID: PMC2946283.
    Citations: 32     Fields:    Translation:HumansCells
  19. Pfannkuche K, Fatima A, Gupta MK, Dieterich R, Hescheler J. Initial colony morphology-based selection for iPS cells derived from adult fibroblasts is substantially improved by temporary UTF1-based selection. PLoS One. 2010 Mar 08; 5(3):e9580. PMID: 20221450; PMCID: PMC2833193.
    Citations: 10     Fields:    Translation:AnimalsCells
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.