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profileChristopher J McDougle, M.D.

TitleNancy Lurie Marks Professor of Psychiatry
InstitutionMassachusetts General Hospital
DepartmentPsychiatry
AddressMassachusetts General Hospital
Dept of Psychiatry
55 Fruit St
Boston MA 02114
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01MH083739     (MCDOUGLE, CHRISTOPHER J)Jul 1, 2010 - Sep 30, 2014
NIH/NIMH
1/4-RUPP Autism Network: Guanfacine for the Treatment of Hyperactivity in PDD
Role: Principal Investigator

R01MH077600     (MCDOUGLE, CHRISTOPHER J)Apr 1, 2007 - Mar 31, 2014
NIH/NIMH
Targeted Pharmacologic Interventions for Autism
Role: Principal Investigator

R01MH072964     (MCDOUGLE, CHRISTOPHER J)Jul 1, 2005 - May 31, 2011
NIH/NIMH
Novel Pharmacological Strategies in Autism
Role: Principal Investigator

U10MH066766     (MCDOUGLE, CHRISTOPHER J)Sep 15, 2002 - Jul 31, 2008
NIH/NIMH
RUPP-PI
Role: Principal Investigator

N01MH070001     (MCDOUGLE, CHRISTOPHER J)Sep 30, 1997 - Mar 31, 2001
NIH/NIMH
RESEARCH UNITS ON PEDIATRIC PSYCHOPHARMACOLOGY--AUTISM-278970001
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Criado KK, Sharp WG, McCracken CE, De Vinck-Baroody O, Dong L, Aman MG, McDougle CJ, McCracken JT, Eugene Arnold L, Weitzman C, Leventhal JM, Vitiello B, Scahill L. Overweight and obese status in children with autism spectrum disorder and disruptive behavior. Autism. 2017 Mar 01; 1362361316683888. PMID: 28325061.
    View in: PubMed
  2. Wink LK, Minshawi NF, Shaffer RC, Plawecki MH, Posey DJ, Horn PS, Adams R, Pedapati EV, Schaefer TL, McDougle CJ, Swiezy NB, Erickson CA. d-Cycloserine enhances durability of social skills training in autism spectrum disorder. Mol Autism. 2017; 8:2. PMID: 28138381.
    View in: PubMed
  3. Neumeyer AM, Cano Sokoloff N, McDonnell E, Macklin EA, McDougle CJ, Misra M. Bone microarchitecture in adolescent boys with autism spectrum disorder. Bone. 2017 Apr; 97:139-146. PMID: 28088646.
    View in: PubMed
  4. Mody M, Shui AM, Nowinski LA, Golas SB, Ferrone C, O'Rourke JA, McDougle CJ. Communication Deficits and the Motor System: Exploring Patterns of Associations in Autism Spectrum Disorder (ASD). J Autism Dev Disord. 2017 Jan; 47(1):155-162. PMID: 27785593.
    View in: PubMed
  5. Scahill L, Bearss K, Sarhangian R, McDougle CJ, Arnold LE, Aman MG, McCracken JT, Tierney E, Gillespie S, Postorino V, Vitiello B. Using a Patient-Centered Outcome Measure to Test Methylphenidate Versus Placebo in Children with Autism Spectrum Disorder. J Child Adolesc Psychopharmacol. 2017 Mar; 27(2):125-131. PMID: 27893955.
    View in: PubMed
  6. Neumeyer AM, Cano Sokoloff N, McDonnell E, Macklin EA, McDougle CJ, Misra M. Bone Accrual in Males with Autism Spectrum Disorder. J Pediatr. 2017 Feb; 181:195-201.e6. PMID: 27887681.
    View in: PubMed
  7. Vo LC, Snyder C, McCracken C, McDougle CJ, McCracken JT, Aman MG, Tierney E, Arnold LE, Levi D, Kelleman M, Carroll D, Morrissey J, Vitiello B, Scahill L. No Apparent Cardiac Conduction Effects of Acute Treatment with Risperidone in Children with Autism Spectrum Disorder. J Child Adolesc Psychopharmacol. 2016 Dec; 26(10):900-908. PMID: 27726426.
    View in: PubMed
  8. McDougle CJ. Atypical Antipsychotic-Induced Weight Gain in Children and Adolescents: Sometimes Less Is More. JAMA Psychiatry. 2016 Sep 01; 73(9):899-901. PMID: 27556412.
    View in: PubMed
  9. Krystal JH, Abi-Dargham A, Akbarian S, Arnsten AFT, Barch DM, Bearden CE, Braff DL, Brown ES, Bullmore ET, Carlezon WA, Carter CS, Cook EH, Daskalakis ZJ, DiLeone RJ, Duman RS, Grace AA, Hariri AR, Harrison PJ, Hiroi N, Kenny PJ, Kleinman JE, Krystal AD, Lewis DA, Lipska BK, Marder SR, Mason GF, Mathalon DH, McClung CA, McDougle CJ, McIntosh AM, McMahon FJ, Mirnics K, Monteggia LM, Narendran R, Nestler EJ, Neumeister A, O'Donovan MC, Öngür D, Pariante CM, Paulus MP, Pearlson G, Phillips ML, Pine DS, Pizzagalli DA, Pletnikov MV, Ragland JD, Rapoport JL, Ressler KJ, Russo SJ, Sanacora G, Sawa A, Schatzberg AF, Shaham Y, Shamay-Tsoory SG, Sklar P, State MW, Stein MB, Strakowski SM, Taylor SF, Turecki G, Turetsky BI, Weissman MM, Zachariou V, Zarate CA, Zubieta JK. Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research. Biol Psychiatry. 2016 Jul 15; 80(2):84-86. PMID: 27346079.
    View in: PubMed
  10. Rengit AC, McKowen JW, O'Brien J, Howe YJ, McDougle CJ. Brief Report: Autism Spectrum Disorder and Substance Use Disorder: A Review and Case Study. J Autism Dev Disord. 2016 Jul; 46(7):2514-9. PMID: 26944591.
    View in: PubMed
  11. Alexander-Bloch AF, McDougle CJ, Ullman Z, Sweetser DA. IQSEC2 and X-linked syndromal intellectual disability. Psychiatr Genet. 2016 Jun; 26(3):101-8. PMID: 27010919.
    View in: PubMed
  12. McGrath LM, Oates JM, Dai YG, Dodd HF, Waxler J, Clements CC, Weill S, Hoffnagle A, Anderson E, MacRae R, Mullett J, McDougle CJ, Pober BR, Smoller JW. Attention Bias to Emotional Faces Varies by IQ and Anxiety in Williams Syndrome. J Autism Dev Disord. 2016 06; 46(6):2174-85. PMID: 26886469; PMCID: PMC4860354 [Available on 06/01/17].
  13. Jacobs J, Schwartz A, McDougle CJ, Skotko BG. Rapid clinical deterioration in an individual with Down syndrome. Am J Med Genet A. 2016 Jul; 170(7):1899-902. PMID: 27149638.
    View in: PubMed
  14. Wink LK, Adams R, Wang Z, Klaunig JE, Plawecki MH, Posey DJ, McDougle CJ, Erickson CA. A randomized placebo-controlled pilot study of N-acetylcysteine in youth with autism spectrum disorder. Mol Autism. 2016; 7:26. PMID: 27103982; PMCID: PMC4839099.
  15. Scahill L, Jeon S, Boorin SJ, McDougle CJ, Aman MG, Dziura J, McCracken JT, Caprio S, Arnold LE, Nicol G, Deng Y, Challa SA, Vitiello B. Weight Gain and Metabolic Consequences of Risperidone in Young Children With Autism Spectrum Disorder. J Am Acad Child Adolesc Psychiatry. 2016 May; 55(5):415-23. PMID: 27126856; PMCID: PMC4851735 [Available on 05/01/17].
  16. Accordino RE, Kidd C, Politte LC, Henry CA, McDougle CJ. Psychopharmacological interventions in autism spectrum disorder. Expert Opin Pharmacother. 2016; 17(7):937-52. PMID: 26891879.
    View in: PubMed
  17. Broder-Fingert S, Shui A, Ferrone C, Iannuzzi D, Cheng ER, Giauque A, Connors S, McDougle CJ, Donelan K, Neumeyer A, Kuhlthau K. A Pilot Study of Autism-Specific Care Plans During Hospital Admission. Pediatrics. 2016 Feb; 137 Suppl 2:S196-204. PMID: 26908475.
    View in: PubMed
  18. Minshawi NF, Wink LK, Shaffer R, Plawecki MH, Posey DJ, Liu H, Hurwitz S, McDougle CJ, Swiezy NB, Erickson CA. A randomized, placebo-controlled trial of D-cycloserine for the enhancement of social skills training in autism spectrum disorders. Mol Autism. 2016; 7:2. PMID: 26770664; PMCID: PMC4712595.
  19. Calarge CA, Ziegler EE, Del Castillo N, Aman M, McDougle CJ, Scahill L, McCracken JT, Arnold LE. Iron homeostasis during risperidone treatment in children and adolescents. J Clin Psychiatry. 2015 Nov; 76(11):1500-5. PMID: 26301448.
    View in: PubMed
  20. Wink LK, Pedapati EV, Horn PS, McDougle CJ, Erickson CA. Multiple Antipsychotic Medication Use in Autism Spectrum Disorder. J Child Adolesc Psychopharmacol. 2017 Feb; 27(1):91-94. PMID: 26465194.
    View in: PubMed
  21. Scahill L, McCracken JT, King BH, Rockhill C, Shah B, Politte L, Sanders R, Minjarez M, Cowen J, Mullett J, Page C, Ward D, Deng Y, Loo S, Dziura J, McDougle CJ. Extended-Release Guanfacine for Hyperactivity in Children With Autism Spectrum Disorder. Am J Psychiatry. 2015 Dec; 172(12):1197-206. PMID: 26315981.
    View in: PubMed
  22. Aman M, Rettiganti M, Nagaraja HN, Hollway JA, McCracken J, McDougle CJ, Tierney E, Scahill L, Arnold LE, Hellings J, Posey DJ, Swiezy NB, Ghuman J, Grados M, Shah B, Vitiello B. Tolerability, Safety, and Benefits of Risperidone in Children and Adolescents with Autism: 21-Month Follow-up After 8-Week Placebo-Controlled Trial. J Child Adolesc Psychopharmacol. 2015 Aug; 25(6):482-93. PMID: 26262903; PMCID: PMC4545698.
  23. Chowdhury M, Aman MG, Lecavalier L, Smith T, Johnson C, Swiezy N, McCracken JT, King B, McDougle CJ, Bearss K, Deng Y, Scahill L. Factor structure and psychometric properties of the revised Home Situations Questionnaire for autism spectrum disorder: The Home Situations Questionnaire-Autism Spectrum Disorder. Autism. 2016 Jul; 20(5):528-37. PMID: 26187059.
    View in: PubMed
  24. Dominick K, Wink LK, McDougle CJ, Erickson CA. A Retrospective Naturalistic Study of Ziprasidone for Irritability in Youth with Autism Spectrum Disorder. J Child Adolesc Psychopharmacol. 2015 Jun; 25(5):397-401. PMID: 26091194.
    View in: PubMed
  25. Minshawi NF, Hurwitz S, Morriss D, McDougle CJ. Multidisciplinary assessment and treatment of self-injurious behavior in autism spectrum disorder and intellectual disability: integration of psychological and biological theory and approach. J Autism Dev Disord. 2015 Jun; 45(6):1541-68. PMID: 25395094.
    View in: PubMed
  26. Scahill L, Sukhodolsky DG, Anderberg E, Dimitropoulos A, Dziura J, Aman MG, McCracken J, Tierney E, Hallett V, Katz K, Vitiello B, McDougle C. Sensitivity of the modified Children's Yale-Brown Obsessive Compulsive Scale to detect change: Results from two multi-site trials. Autism. 2016 Feb; 20(2):145-52. PMID: 25882391.
    View in: PubMed
  27. Crowley B, Howe YJ, McDougle CJ. Topiramate for weight loss in two young adult women with autism spectrum disorder. J Child Adolesc Psychopharmacol. 2015 Mar; 25(2):183-5. PMID: 25746055.
    View in: PubMed
  28. Hulvershorn LA, Schroeder KM, Wink LK, Erickson CA, McDougle CJ. Psychopharmacologic treatment of children prenatally exposed to drugs of abuse. Hum Psychopharmacol. 2015 May; 30(3):164-72. PMID: 25737371.
    View in: PubMed
  29. Neumeyer AM, O'Rourke JA, Massa A, Lee H, Lawson EA, McDougle CJ, Misra M. Brief report: bone fractures in children and adults with autism spectrum disorders. J Autism Dev Disord. 2015 Mar; 45(3):881-7. PMID: 25193141; PMCID: PMC4590779.
  30. Zürcher NR, Bhanot A, McDougle CJ, Hooker JM. A systematic review of molecular imaging (PET and SPECT) in autism spectrum disorder: current state and future research opportunities. Neurosci Biobehav Rev. 2015 May; 52:56-73. PMID: 25684726.
    View in: PubMed
  31. Pouget JG, Gonçalves VF, Nurmi EL, P Laughlin C, Mallya KS, McCracken JT, Aman MG, McDougle CJ, Scahill L, Misener VL, Tiwari AK, Zai CC, Brandl EJ, Felsky D, Leung AQ, Lieberman JA, Meltzer HY, Potkin SG, Niedling C, Steimer W, Leucht S, Knight J, Müller DJ, Kennedy JL. Investigation of TSPO variants in schizophrenia and antipsychotic treatment outcomes. Pharmacogenomics. 2015 Jan; 16(1):5-22. PMID: 25560467.
    View in: PubMed
  32. Vahabzadeh A, Landino SM, Finger BC, Carlezon WA, McDougle CJ. Neural targets in the study and treatment of social cognition in autism spectrum disorder. Handb Exp Pharmacol. 2015; 228:309-34. PMID: 25977088.
    View in: PubMed
  33. McDougle CJ, Landino SM, Vahabzadeh A, O'Rourke J, Zurcher NR, Finger BC, Palumbo ML, Helt J, Mullett JE, Hooker JM, Carlezon WA. Toward an immune-mediated subtype of autism spectrum disorder. Brain Res. 2015 Aug 18; 1617:72-92. PMID: 25445995.
    View in: PubMed
  34. Bowers K, Wink LK, Pottenger A, McDougle CJ, Erickson C. Phenotypic differences in individuals with autism spectrum disorder born preterm and at term gestation. Autism. 2015 Aug; 19(6):758-63. PMID: 25192860.
    View in: PubMed
  35. Erickson CA, Ray B, Maloney B, Wink LK, Bowers K, Schaefer TL, McDougle CJ, Sokol DK, Lahiri DK. Impact of acamprosate on plasma amyloid-ß precursor protein in youth: a pilot analysis in fragile X syndrome-associated and idiopathic autism spectrum disorder suggests a pharmacodynamic protein marker. J Psychiatr Res. 2014 Dec; 59:220-8. PMID: 25300441; PMCID: PMC4253657 [Available on 12/01/15].
  36. Minshawi NF, Hurwitz S, Fodstad JC, Biebl S, Morriss DH, McDougle CJ. The association between self-injurious behaviors and autism spectrum disorders. Psychol Res Behav Manag. 2014; 7:125-36. PMID: 24748827; PMCID: PMC3990505.
  37. Erickson CA, Wink LK, Early MC, Stiegelmeyer E, Mathieu-Frasier L, Patrick V, McDougle CJ. Brief report: Pilot single-blind placebo lead-in study of acamprosate in youth with autistic disorder. J Autism Dev Disord. 2014 Apr; 44(4):981-7. PMID: 24052275.
    View in: PubMed
  38. Politte LC, Henry CA, McDougle CJ. Psychopharmacological interventions in autism spectrum disorder. Harv Rev Psychiatry. 2014 Mar-Apr; 22(2):76-92. PMID: 24614763.
    View in: PubMed
  39. Frazier JA, McDougle CJ. Special issue on autism spectrum disorders. Introduction. Harv Rev Psychiatry. 2014 Mar-Apr; 22(2):61-4. PMID: 24614761.
    View in: PubMed
  40. Hazen EP, Stornelli JL, O'Rourke JA, Koesterer K, McDougle CJ. Sensory symptoms in autism spectrum disorders. Harv Rev Psychiatry. 2014 Mar-Apr; 22(2):112-24. PMID: 24614766.
    View in: PubMed
  41. Adler BA, Wink LK, Early M, Shaffer R, Minshawi N, McDougle CJ, Erickson CA. Drug-refractory aggression, self-injurious behavior, and severe tantrums in autism spectrum disorders: a chart review study. Autism. 2015 Jan; 19(1):102-6. PMID: 24571823.
    View in: PubMed
  42. Wink LK, Early M, Schaefer T, Pottenger A, Horn P, McDougle CJ, Erickson CA. Body mass index change in autism spectrum disorders: comparison of treatment with risperidone and aripiprazole. J Child Adolesc Psychopharmacol. 2014 Mar; 24(2):78-82. PMID: 24564519.
    View in: PubMed
  43. Pineiro ML, Roberts AM, Waxler JL, Mullett JE, Pober BR, McDougle CJ. N-acetylcysteine for neuropsychiatric symptoms in a woman with Williams syndrome. J Child Neurol. 2014 Nov; 29(11):NP135-8. PMID: 24396132.
    View in: PubMed
  44. Carroll D, Hallett V, McDougle CJ, Aman MG, McCracken JT, Tierney E, Arnold LE, Sukhodolsky DG, Lecavalier L, Handen BL, Swiezy N, Johnson C, Bearss K, Vitiello B, Scahill L. Examination of aggression and self-injury in children with autism spectrum disorders and serious behavioral problems. Child Adolesc Psychiatr Clin N Am. 2014 Jan; 23(1):57-72. PMID: 24231167; PMCID: PMC4212264.
  45. Scahill L, Dimitropoulos A, McDougle CJ, Aman MG, Feurer ID, McCracken JT, Tierney E, Pu J, White S, Lecavalier L, Hallett V, Bearss K, King B, Arnold LE, Vitiello B. Children's Yale-Brown obsessive compulsive scale in autism spectrum disorder: component structure and correlates of symptom checklist. J Am Acad Child Adolesc Psychiatry. 2014 Jan; 53(1):97-107.e1. PMID: 24342389; PMCID: PMC3999641.
  46. Hallett V, Lecavalier L, Sukhodolsky DG, Cipriano N, Aman MG, McCracken JT, McDougle CJ, Tierney E, King BH, Hollander E, Sikich L, Bregman J, Anagnostou E, Donnelly C, Katsovich L, Dukes K, Vitiello B, Gadow K, Scahill L. Exploring the manifestations of anxiety in children with autism spectrum disorders. J Autism Dev Disord. 2013 Oct; 43(10):2341-52. PMID: 23400347; PMCID: PMC4038127.
  47. Lange N, McDougle C. Help for the child with autism. Sci Am. 2013 Oct; 309(4):72-7. PMID: 24137859.
    View in: PubMed
  48. McCracken JT, Badashova KK, Posey DJ, Aman MG, Scahill L, Tierney E, Arnold LE, Vitiello B, Whelan F, Chuang SZ, Davies M, Shah B, McDougle CJ, Nurmi EL. Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders. Pharmacogenomics J. 2014 Jun; 14(3):295-302. PMID: 23856854; PMCID: PMC4034115.
  49. Landsberger SA, Scott EL, Hulvershorn LA, Chapleau KM, Diaz DR, McDougle CJ. Mentorship of clinical-track junior faculty: impact of a facilitated peer-mentoring program to promote scholarly productivity. Acad Psychiatry. 2013 Jul 01; 37(4):288-9. PMID: 23820920.
    View in: PubMed
  50. Hazen EP, McDougle CJ, Volkmar FR. Changes in the diagnostic criteria for autism in DSM-5: controversies and concerns. J Clin Psychiatry. 2013 Jul; 74(7):739-40. PMID: 23945452.
    View in: PubMed
  51. Nurmi EL, Spilman SL, Whelan F, Scahill LL, Aman MG, McDougle CJ, Arnold LE, Handen B, Johnson C, Sukhodolsky DG, Posey DJ, Lecavalier L, Stigler KA, Ritz L, Tierney E, Vitiello B, McCracken JT. Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies. Transl Psychiatry. 2013 Jun 25; 3:e274. PMID: 23799528; PMCID: PMC3693401.
  52. Vahabzadeh A, McDougle CJ. Maternal folic acid supplementation and risk of autism. JAMA. 2013 Jun 05; 309(21):2208. PMID: 23736720.
    View in: PubMed
  53. Storch EA, Goddard AW, Grant JE, De Nadai AS, Goodman WK, Mutch PJ, Medlock C, Odlaug B, McDougle CJ, Murphy TK. Double-blind, placebo-controlled, pilot trial of paliperidone augmentation in serotonin reuptake inhibitor-resistant obsessive-compulsive disorder. J Clin Psychiatry. 2013 Jun; 74(6):e527-32. PMID: 23842022.
    View in: PubMed
  54. McDougle CJ. Sounding a wake-up call: improving the lives of adults with autism. J Am Acad Child Adolesc Psychiatry. 2013 Jun; 52(6):566-8. PMID: 23702444.
    View in: PubMed
  55. Handen BL, Johnson CR, Butter EM, Lecavalier L, Scahill L, Aman MG, McDougle CJ, Arnold LE, Swiezy NB, Sukhodolsky DG, Mulick JA, White SW, Bearss K, Hollway JA, Stigler KA, Dziura J, Yu S, Sacco K, Vitiello B. Use of a Direct Observational Measure in a Trial of Risperidone and Parent Training in Children with Pervasive Developmental Disorders. J Dev Phys Disabil. 2013 Jun 01; 25(3):355-371. PMID: 23730123.
    View in: PubMed
  56. Politte LC, McDougle CJ. Atypical antipsychotics in the treatment of children and adolescents with pervasive developmental disorders. Psychopharmacology (Berl). 2014 Mar; 231(6):1023-36. PMID: 23552907.
    View in: PubMed
  57. Scahill L, Hallett V, Aman MG, McDougle CJ, Eugene Arnold L, McCracken JT, Tierney E, Deng Y, Dziura J, Vitiello B. Brief Report: social disability in autism spectrum disorder: results from Research Units on Pediatric Psychopharmacology (RUPP) Autism Network trials. J Autism Dev Disord. 2013 Mar; 43(3):739-46. PMID: 23104617; PMCID: PMC3886122.
  58. Erickson CA, Wink LK, Ray B, Early MC, Stiegelmeyer E, Mathieu-Frasier L, Patrick V, Lahiri DK, McDougle CJ. Impact of acamprosate on behavior and brain-derived neurotrophic factor: an open-label study in youth with fragile X syndrome. Psychopharmacology (Berl). 2013 Jul; 228(1):75-84. PMID: 23436129.
    View in: PubMed
  59. McDougle CJ, Carlezon WA. Neuroinflammation and autism: toward mechanisms and treatments. Neuropsychopharmacology. 2013 Jan; 38(1):241-2. PMID: 23147483; PMCID: PMC3521978.
  60. Arnold LE, Aman MG, Li X, Butter E, Humphries K, Scahill L, Lecavalier L, McDougle CJ, Swiezy NB, Handen B, Wilson K, Stigler KA. Research Units of Pediatric Psychopharmacology (RUPP) autism network randomized clinical trial of parent training and medication: one-year follow-up. J Am Acad Child Adolesc Psychiatry. 2012 Nov; 51(11):1173-84. PMID: 23101743; PMCID: PMC3772659.
  61. Doyle CA, McDougle CJ. Pharmacologic treatments for the behavioral symptoms associated with autism spectrum disorders across the lifespan. Dialogues Clin Neurosci. 2012 Sep; 14(3):263-79. PMID: 23226952; PMCID: PMC3513681.
  62. Ho JG, Caldwell RL, McDougle CJ, Orsagh-Yentis DK, Erickson CA, Posey DJ, Stigler KA. The effects of aripiprazole on electrocardiography in children with pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2012 Aug; 22(4):277-83. PMID: 22849533; PMCID: PMC3472675.
  63. Anney R, Klei L, Pinto D, Almeida J, Bacchelli E, Baird G, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Casey J, Conroy J, Correia C, Corsello C, Crawford EL, de Jonge M, Delorme R, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Gilbert J, Gillberg C, Glessner JT, Green A, Green J, Guter SJ, Heron EA, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Jacob S, Kenny GP, Kim C, Kolevzon A, Kustanovich V, Lajonchere CM, Lamb JA, Law-Smith M, Leboyer M, Le Couteur A, Leventhal BL, Liu XQ, Lombard F, Lord C, Lotspeich L, Lund SC, Magalhaes TR, Mantoulan C, McDougle CJ, Melhem NM, Merikangas A, Minshew NJ, Mirza GK, Munson J, Noakes C, Nygren G, Papanikolaou K, Pagnamenta AT, Parrini B, Paton T, Pickles A, Posey DJ, Poustka F, Ragoussis J, Regan R, Roberts W, Roeder K, Roge B, Rutter ML, Schlitt S, Shah N, Sheffield VC, Soorya L, Sousa I, Stoppioni V, Sykes N, Tancredi R, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Vorstman JA, Wallace S, Wing K, Wittemeyer K, Wood S, Zurawiecki D, Zwaigenbaum L, Bailey AJ, Battaglia A, Cantor RM, Coon H, Cuccaro ML, Dawson G, Ennis S, Freitag CM, Geschwind DH, Haines JL, Klauck SM, McMahon WM, Maestrini E, Miller J, Monaco AP, Nelson SF, Nurnberger JI, Oliveira G, Parr JR, Pericak-Vance MA, Piven J, Schellenberg GD, Scherer SW, Vicente AM, Wassink TH, Wijsman EM, Betancur C, Buxbaum JD, Cook EH, Gallagher L, Gill M, Hallmayer J, Paterson AD, Sutcliffe JS, Szatmari P, Vieland VJ, Hakonarson H, Devlin B. Individual common variants exert weak effects on the risk for autism spectrum disorders. Hum Mol Genet. 2012 Nov 01; 21(21):4781-92. PMID: 22843504; PMCID: PMC3471395.
  64. Early MC, Erickson CA, Wink LK, McDougle CJ, Scott EL. Case report: 16-Year-old male with autistic disorder with preoccupation with female feet. J Autism Dev Disord. 2012 Jun; 42(6):1133-7. PMID: 21818675.
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  65. Farmer C, Lecavalier L, Yu S, Eugene Arnold L, McDougle CJ, Scahill L, Handen B, Johnson CR, Stigler KA, Bearss K, Swiezy NB, Aman MG. Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems. J Autism Dev Disord. 2012 Jun; 42(6):1037-44. PMID: 21822762; PMCID: PMC3911789.
  66. Stigler KA, Mullett JE, Erickson CA, Posey DJ, McDougle CJ. Paliperidone for irritability in adolescents and young adults with autistic disorder. Psychopharmacology (Berl). 2012 Sep; 223(2):237-45. PMID: 22549762.
    View in: PubMed
  67. Doyle CA, McDougle CJ. Pharmacotherapy to control behavioral symptoms in children with autism. Expert Opin Pharmacother. 2012 Aug; 13(11):1615-29. PMID: 22550944.
    View in: PubMed
  68. Scahill L, McDougle CJ, Aman MG, Johnson C, Handen B, Bearss K, Dziura J, Butter E, Swiezy NG, Arnold LE, Stigler KA, Sukhodolsky DD, Lecavalier L, Pozdol SL, Nikolov R, Hollway JA, Korzekwa P, Gavaletz A, Kohn AE, Koenig K, Grinnon S, Mulick JA, Yu S, Vitiello B. Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems. J Am Acad Child Adolesc Psychiatry. 2012 Feb; 51(2):136-46. PMID: 22265360; PMCID: PMC3941712.
  69. Orsagh-Yentis DK, Wink LK, Stigler KA, Erickson CA, McDougle CJ. Buspirone for bruxism in a child with pervasive developmental disorder-not otherwise specified. J Child Adolesc Psychopharmacol. 2011 Dec; 21(6):643-5. PMID: 22136097.
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  137. Morris DR, Meighen KG, McDougle CJ. Acute onset of obsessive-compulsive disorder in an adolescent with acute lymphoblastic leukemia. Psychosomatics. 2005 Sep-Oct; 46(5):458-60. PMID: 16145191.
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  138. Kratochvil CJ, Findling RL, McDougle CJ, Scahill L, Hamarman S. Pharmacological management of agitation and aggression in an adolescent with autism. J Am Acad Child Adolesc Psychiatry. 2005 Aug; 44(8):829-32. PMID: 16034286.
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  139. McDougle CJ, Scahill L, Aman MG, McCracken JT, Tierney E, Davies M, Arnold LE, Posey DJ, Martin A, Ghuman JK, Shah B, Chuang SZ, Swiezy NB, Gonzalez NM, Hollway J, Koenig K, McGough JJ, Ritz L, Vitiello B. Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology. Am J Psychiatry. 2005 Jun; 162(6):1142-8. PMID: 15930063.
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  140. Walsh KH, McDougle CJ. Pharmacological strategies for trichotillomania. Expert Opin Pharmacother. 2005 Jun; 6(6):975-84. PMID: 15952925.
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  141. Vitiello B, Aman MG, Scahill L, McCracken JT, McDougle CJ, Tierney E, Davies M, Arnold LE. Research knowledge among parents of children participating in a randomized clinical trial. J Am Acad Child Adolesc Psychiatry. 2005 Feb; 44(2):145-9. PMID: 15689727.
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  142. McDougle CJ, Erickson CA, Stigler KA, Posey DJ. Neurochemistry in the pathophysiology of autism. J Clin Psychiatry. 2005; 66 Suppl 10:9-18. PMID: 16401145.
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  143. Corson AH, Barkenbus JE, Posey DJ, Stigler KA, McDougle CJ. A retrospective analysis of quetiapine in the treatment of pervasive developmental disorders. J Clin Psychiatry. 2004 Nov; 65(11):1531-6. PMID: 15554768.
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  144. Posey DJ, Kem DL, Swiezy NB, Sweeten TL, Wiegand RE, McDougle CJ. A pilot study of D-cycloserine in subjects with autistic disorder. Am J Psychiatry. 2004 Nov; 161(11):2115-7. PMID: 15514414.
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  145. Walsh KH, McDougle CJ. Pharmacological augmentation strategies for treatment-resistant obsessive-compulsive disorder. Expert Opin Pharmacother. 2004 Oct; 5(10):2059-67. PMID: 15461541.
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  146. McDougle CJ. Methylphenidate an effective treatment for ADHD? J Autism Dev Disord. 2004 Oct; 34(5):593-4. PMID: 15628613.
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  147. Sweeten TL, Posey DJ, McDougle CJ. Brief report: autistic disorder in three children with cytomegalovirus infection. J Autism Dev Disord. 2004 Oct; 34(5):583-6. PMID: 15628611.
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  148. Tyrka AR, Carpenter LL, McDougle CJ, Kirwin PD, Owens MJ, Nemeroff CB, Strong DR, Price LH. Increased cerebrospinal fluid corticotropin-releasing factor concentrations during tryptophan depletion in healthy adults. Biol Psychiatry. 2004 Oct 01; 56(7):531-4. PMID: 15450791.
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  149. Martin A, Scahill L, Anderson GM, Aman M, Arnold LE, McCracken J, McDougle CJ, Tierney E, Chuang S, Vitiello B. Weight and leptin changes among risperidone-treated youths with autism: 6-month prospective data. Am J Psychiatry. 2004 Jun; 161(6):1125-7. PMID: 15169706.
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  150. Carpenter LL, Tyrka AR, McDougle CJ, Malison RT, Owens MJ, Nemeroff CB, Price LH. Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects. Neuropsychopharmacology. 2004 Apr; 29(4):777-84. PMID: 14702025.
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  151. Sweeten TL, Posey DJ, Shankar S, McDougle CJ. High nitric oxide production in autistic disorder: a possible role for interferon-gamma. Biol Psychiatry. 2004 Feb 15; 55(4):434-7. PMID: 14960298.
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  152. Meighen KG, Shelton HM, McDougle CJ. Ziprasidone treatment of two adolescents with psychosis. J Child Adolesc Psychopharmacol. 2004; 14(1):137-42. PMID: 15142401.
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  153. Posey DJ, Puntney JI, Sasher TM, Kem DL, McDougle CJ. Guanfacine treatment of hyperactivity and inattention in pervasive developmental disorders: a retrospective analysis of 80 cases. J Child Adolesc Psychopharmacol. 2004; 14(2):233-41. PMID: 15319020.
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  154. Stigler KA, Posey DJ, McDougle CJ. Aripiprazole for maladaptive behavior in pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2004; 14(3):455-63. PMID: 15650503.
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  155. Stigler KA, Potenza MN, Posey DJ, McDougle CJ. Weight gain associated with atypical antipsychotic use in children and adolescents: prevalence, clinical relevance, and management. Paediatr Drugs. 2004; 6(1):33-44. PMID: 14969568.
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  156. Hazaray E, Ehret J, Posey DJ, Petti TA, McDougle CJ. Intramuscular ziprasidone for acute agitation in adolescents. J Child Adolesc Psychopharmacol. 2004; 14(3):464-70. PMID: 15650504.
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  157. Stigler KA, Desmond LA, Posey DJ, Wiegand RE, McDougle CJ. A naturalistic retrospective analysis of psychostimulants in pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2004; 14(1):49-56. PMID: 15142391.
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  158. Arnold LE, Vitiello B, McDougle C, Scahill L, Shah B, Gonzalez NM, Chuang S, Davies M, Hollway J, Aman MG, Cronin P, Koenig K, Kohn AE, McMahon DJ, Tierney E. Parent-defined target symptoms respond to risperidone in RUPP autism study: customer approach to clinical trials. J Am Acad Child Adolesc Psychiatry. 2003 Dec; 42(12):1443-50. PMID: 14627879.
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  159. Sweeten TL, Bowyer SL, Posey DJ, Halberstadt GM, McDougle CJ. Increased prevalence of familial autoimmunity in probands with pervasive developmental disorders. Pediatrics. 2003 Nov; 112(5):e420. PMID: 14595086.
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  160. Sweeten TL, Posey DJ, McDougle CJ. High blood monocyte counts and neopterin levels in children with autistic disorder. Am J Psychiatry. 2003 Sep; 160(9):1691-3. PMID: 12944347.
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  161. McDougle CJ, Stigler KA, Posey DJ. Treatment of aggression in children and adolescents with autism and conduct disorder. J Clin Psychiatry. 2003; 64 Suppl 4:16-25. PMID: 12672261.
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  162. Carpenter LL, Heninger GR, McDougle CJ, Tyrka AR, Epperson CN, Price LH. Cerebrospinal fluid interleukin-6 in obsessive-compulsive disorder and trichotillomania. Psychiatry Res. 2002 Nov 15; 112(3):257-62. PMID: 12450635.
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  163. McDougle CJ, Posey D. Genetics of childhood disorders: XLIV. autism, part 3: psychopharmacology of autism. J Am Acad Child Adolesc Psychiatry. 2002 Nov; 41(11):1380-3. PMID: 12410082.
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  164. Marek GJ, Carpenter LL, McDougle CJ, Price LH. Synergistic action of 5-HT2A antagonists and selective serotonin reuptake inhibitors in neuropsychiatric disorders. Neuropsychopharmacology. 2003 Feb; 28(2):402-12. PMID: 12589395.
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  165. McDougle CJ, Kem DL, Posey DJ. Case series: use of ziprasidone for maladaptive symptoms in youths with autism. J Am Acad Child Adolesc Psychiatry. 2002 Aug; 41(8):921-7. PMID: 12164181.
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  166. McCracken JT, McGough J, Shah B, Cronin P, Hong D, Aman MG, Arnold LE, Lindsay R, Nash P, Hollway J, McDougle CJ, Posey D, Swiezy N, Kohn A, Scahill L, Martin A, Koenig K, Volkmar F, Carroll D, Lancor A, Tierney E, Ghuman J, Gonzalez NM, Grados M, Vitiello B, Ritz L, Davies M, Robinson J, McMahon D. Risperidone in children with autism and serious behavioral problems. N Engl J Med. 2002 Aug 01; 347(5):314-21. PMID: 12151468.
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  167. Posey DJ, McDougle CJ. Risperidone: a potential treatment for autism. Curr Opin Investig Drugs. 2002 Aug; 3(8):1212-6. PMID: 12211417.
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  169. Kem DL, Posey DJ, McDougle CJ. Priapism associated with trazodone in an adolescent with autism. J Am Acad Child Adolesc Psychiatry. 2002 Jul; 41(7):758. PMID: 12108798.
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  170. George TP, Potenza MN, Degen K, Sernyak MJ, Woods S, McDougle CJ. Acute tryptophan depletion in schizophrenic patients treated with clozapine. Arch Gen Psychiatry. 2002 Mar; 59(3):291-2. PMID: 11879174.
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  171. Sweeten TL, Posey DJ, Shekhar A, McDougle CJ. The amygdala and related structures in the pathophysiology of autism. Pharmacol Biochem Behav. 2002 Mar; 71(3):449-55. PMID: 11830179.
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  172. Sweeten TL, Ferris M, McDougle CJ, Kwo P, Taylor MW. Induction of indoleamine 2,3-dioxygenase in vivo by IFN-con1. J Interferon Cytokine Res. 2001 Aug; 21(8):631-3. PMID: 11559441.
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  173. Potenza MN, McDougle CJ. Reply to comments on "Olanzapine treatment of children, adolescents, and adults with pervasive developmental disorders: an open-label pilot study". J Clin Psychopharmacol. 2001 Apr; 21(2):246-7. PMID: 11270929.
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  175. Posey DJ, McDougle CJ. The pathophysiology and treatment of autism. Curr Psychiatry Rep. 2001 Apr; 3(2):101-8. PMID: 11276404.
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  176. Walsh KH, McDougle CJ. Trichotillomania. Presentation, etiology, diagnosis and therapy. Am J Clin Dermatol. 2001; 2(5):327-33. PMID: 11721651.
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  177. Scahill L, McCracken J, McDougle CJ, Aman M, Arnold LE, Tierney E, Cronin P, Davies M, Ghuman J, Gonzalez N, Koenig K, Lindsay R, Martin A, McGough J, Posey DJ, Swiezy N, Volkmar F, Ritz L, Vitiello B. Methodological issues in designing a multisite trial of risperidone in children and adolescents with autism. J Child Adolesc Psychopharmacol. 2001; 11(4):377-88. PMID: 11838820.
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  178. Stigler KA, Potenza MN, McDougle CJ. Tolerability profile of atypical antipsychotics in children and adolescents. Paediatr Drugs. 2001; 3(12):927-42. PMID: 11772153.
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  179. Posey DJ, Guenin KD, Kohn AE, Swiezy NB, McDougle CJ. A naturalistic open-label study of mirtazapine in autistic and other pervasive developmental disorders. J Child Adolesc Psychopharmacol. 2001; 11(3):267-77. PMID: 11642476.
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  180. McDougle CJ, Kresch LE, Posey DJ. Repetitive thoughts and behavior in pervasive developmental disorders: treatment with serotonin reuptake inhibitors. J Autism Dev Disord. 2000 Oct; 30(5):427-35. PMID: 11098879.
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  181. McDougle CJ, Epperson CN, Pelton GH, Wasylink S, Price LH. A double-blind, placebo-controlled study of risperidone addition in serotonin reuptake inhibitor-refractory obsessive-compulsive disorder. Arch Gen Psychiatry. 2000 Aug; 57(8):794-801. PMID: 10920469.
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  182. Posey DJ, McDougle CJ. The pharmacotherapy of target symptoms associated with autistic disorder and other pervasive developmental disorders. Harv Rev Psychiatry. 2000 Jul-Aug; 8(2):45-63. PMID: 10902094.
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  183. Arnold LE, Aman MG, Martin A, Collier-Crespin A, Vitiello B, Tierney E, Asarnow R, Bell-Bradshaw F, Freeman BJ, Gates-Ulanet P, Klin A, McCracken JT, McDougle CJ, McGough JJ, Posey DJ, Scahill L, Swiezy NB, Ritz L, Volkmar F. Assessment in multisite randomized clinical trials of patients with autistic disorder: the Autism RUPP Network. Research Units on Pediatric Psychopharmacology. J Autism Dev Disord. 2000 Apr; 30(2):99-111. PMID: 10832774.
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  184. Klaeger D, McDougle CJ. Secretin in autism--a parent's perspective. J Autism Dev Disord. 2000 Feb; 30(1):72-3. PMID: 10819124.
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  185. McDougle CJ, Scahill L, McCracken JT, Aman MG, Tierney E, Arnold LE, Freeman BJ, Martin A, McGough JJ, Cronin P, Posey DJ, Riddle MA, Ritz L, Swiezy NB, Vitiello B, Volkmar FR, Votolato NA, Walson P. Research Units on Pediatric Psychopharmacology (RUPP) Autism Network. Background and rationale for an initial controlled study of risperidone. Child Adolesc Psychiatr Clin N Am. 2000 Jan; 9(1):201-24. PMID: 10674197.
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  186. Malison RT, Anand A, Pelton GH, Kirwin P, Carpenter L, McDougle CJ, Heninger GR, Price LH. Limited efficacy of ketoconazole in treatment-refractory major depression. J Clin Psychopharmacol. 1999 Oct; 19(5):466-70. PMID: 10505589.
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  187. Longhurst JG, Carpenter LL, Epperson CN, Price LH, McDougle CJ. Effects of catecholamine depletion with AMPT (alpha-methyl-para-tyrosine) in obsessive-compulsive disorder. Biol Psychiatry. 1999 Aug 15; 46(4):573-6. PMID: 10459409.
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  188. Weiss EL, Potenza MN, McDougle CJ, Epperson CN. Olanzapine addition in obsessive-compulsive disorder refractory to selective serotonin reuptake inhibitors: an open-label case series. J Clin Psychiatry. 1999 Aug; 60(8):524-7. PMID: 10485634.
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  189. Posey DI, Litwiller M, Koburn A, McDougle CJ. Paroxetine in autism. J Am Acad Child Adolesc Psychiatry. 1999 Feb; 38(2):111-2. PMID: 9951204.
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  190. Potenza MN, Holmes JP, Kanes SJ, McDougle CJ. Olanzapine treatment of children, adolescents, and adults with pervasive developmental disorders: an open-label pilot study. J Clin Psychopharmacol. 1999 Feb; 19(1):37-44. PMID: 9934941.
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  191. Dartnall NA, Holmes JP, Morgan SN, McDougle CJ. Brief report: two-year control of behavioral symptoms with risperidone in two profoundly retarded adults with autism. J Autism Dev Disord. 1999 Feb; 29(1):87-91. PMID: 10097998.
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  192. Posey DJ, Walsh KH, Wilson GA, McDougle CJ. Risperidone in the treatment of two very young children with autism. J Child Adolesc Psychopharmacol. 1999; 9(4):273-6. PMID: 10630457.
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  193. McDougle CJ, Barr LC, Goodman WK, Price LH. Possible role of neuropeptides in obsessive compulsive disorder. Psychoneuroendocrinology. 1999 Jan; 24(1):1-24. PMID: 10098217.
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  194. Epperson CN, Fasula D, Wasylink S, Price LH, McDougle CJ. Risperidone addition in serotonin reuptake inhibitor-resistant trichotillomania: three cases. J Child Adolesc Psychopharmacol. 1999; 9(1):43-9. PMID: 10357517.
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  195. Potenza MN, Wasylink S, Longhurst JG, Epperson CN, McDougle CJ. Olanzapine augmentation of fluoxetine in the treatment of refractory obsessive-compulsive disorder. J Clin Psychopharmacol. 1998 Oct; 18(5):423-4. PMID: 9790164.
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  197. Cappiello A, McDougle CJ, Delgado PL, Malison RT, Jatlow P, Charney DS, Heninger GR, Price LH. Lithium and desipramine versus desipramine alone in the treatment of severe major depression: a preliminary study. Int Clin Psychopharmacol. 1998 Sep; 13(5):191-8. PMID: 9817623.
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  198. McDougle CJ, Holmes JP, Carlson DC, Pelton GH, Cohen DJ, Price LH. A double-blind, placebo-controlled study of risperidone in adults with autistic disorder and other pervasive developmental disorders. Arch Gen Psychiatry. 1998 Jul; 55(7):633-41. PMID: 9672054.
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  199. Carpenter LL, Anderson GM, Pelton GH, Gudin JA, Kirwin PD, Price LH, Heninger GR, McDougle CJ. Tryptophan depletion during continuous CSF sampling in healthy human subjects. Neuropsychopharmacology. 1998 Jul; 19(1):26-35. PMID: 9608574.
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  200. McDougle CJ, Epperson CN, Price LH, Gelernter J. Evidence for linkage disequilibrium between serotonin transporter protein gene (SLC6A4) and obsessive compulsive disorder. Mol Psychiatry. 1998 May; 3(3):270-3. PMID: 9672904.
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  201. Price LH, Malison RT, McDougle CJ, Pelton GH, Heninger GR. The neurobiology of tryptophan depletion in depression: effects of intravenous tryptophan infusion. Biol Psychiatry. 1998 Mar 01; 43(5):339-47. PMID: 9513749.
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  202. Calvocoressi L, Libman D, Vegso SJ, McDougle CJ, Price LH. Global functioning of inpatients with obsessive-compulsive disorder, schizophrenia, and major depression. Psychiatr Serv. 1998 Mar; 49(3):379-81. PMID: 9525801.
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  203. McDougle CJ, Brodkin ES, Naylor ST, Carlson DC, Cohen DJ, Price LH. Sertraline in adults with pervasive developmental disorders: a prospective open-label investigation. J Clin Psychopharmacol. 1998 Feb; 18(1):62-6. PMID: 9472844.
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  204. Cappiello A, Sernyak MJ, Malison RT, McDougle CJ, Heninger GR, Price LH. Effects of acute tryptophan depletion in lithium-remitted manic patients: a pilot study. Biol Psychiatry. 1997 Dec 01; 42(11):1076-8. PMID: 9386862.
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  205. Longhurst JG, Potenza MN, McDougle CJ. Autism. N Engl J Med. 1997 Nov 20; 337(21):1555-6; author reply 1556-7. PMID: 9380125.
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  206. Price LH, Malison RT, McDougle CJ, McCance-Katz EF, Owen KR, Heninger GR. Neurobiology of tryptophan depletion in depression: effects of m-chlorophenylpiperazine (mCPP). Neuropsychopharmacology. 1997 Nov; 17(5):342-50. PMID: 9348549.
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  207. Price LH, Cappiello A, Malison RT, McDougle CJ, Pelton GH, Schöllnhammer G, Heninger GR. Effects of antiglucocorticoid treatment on 5-HT1A function in depressed patients and healthy subjects. Neuropsychopharmacology. 1997 Oct; 17(4):246-57. PMID: 9326749.
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  208. Barr LC, Goodman WK, Anand A, McDougle CJ, Price LH. Addition of desipramine to serotonin reuptake inhibitors in treatment-resistant obsessive-compulsive disorder. Am J Psychiatry. 1997 Sep; 154(9):1293-5. PMID: 9286191.
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  209. Leckman JF, Grice DE, Boardman J, Zhang H, Vitale A, Bondi C, Alsobrook J, Peterson BS, Cohen DJ, Rasmussen SA, Goodman WK, McDougle CJ, Pauls DL. Symptoms of obsessive-compulsive disorder. Am J Psychiatry. 1997 Jul; 154(7):911-7. PMID: 9210740.
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  210. McDougle CJ, Holmes JP, Bronson MR, Anderson GM, Volkmar FR, Price LH, Cohen DJ. Risperidone treatment of children and adolescents with pervasive developmental disorders: a prospective open-label study. J Am Acad Child Adolesc Psychiatry. 1997 May; 36(5):685-93. PMID: 9136504.
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  211. Epperson CN, Anderson GM, McDougle CJ. Sertraline and breast-feeding. N Engl J Med. 1997 Apr 17; 336(16):1189-90. PMID: 9102576.
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  212. McDougle CJ. Update on pharmacologic management of OCD: agents and augmentation. J Clin Psychiatry. 1997; 58 Suppl 12:11-7. PMID: 9393391.
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  213. Brodkin ES, McDougle CJ, Naylor ST, Cohen DJ, Price LH. Clomipramine in adults with pervasive developmental disorders: a prospective open-label investigation. J Child Adolesc Psychopharmacol. 1997; 7(2):109-21. PMID: 9334896.
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  214. Kirwin PD, Anderson GM, Chappell PB, Saberski L, Leckman JF, Geracioti TD, Heninger GR, Price LH, McDougle CJ. Assessment of diurnal variation of cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in healthy human females. Life Sci. 1997; 60(12):899-907. PMID: 9061047.
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  215. McDougle CJ, Naylor ST, Cohen DJ, Volkmar FR, Heninger GR, Price LH. A double-blind, placebo-controlled study of fluvoxamine in adults with autistic disorder. Arch Gen Psychiatry. 1996 Nov; 53(11):1001-8. PMID: 8911223.
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  216. Cappiello A, Malison RT, McDougle CJ, Vegso SJ, Charney DS, Heninger GR, Price LH. Seasonal variation in neuroendocrine and mood responses to i.v. L-tryptophan in depressed patients and healthy subjects. Neuropsychopharmacology. 1996 Nov; 15(5):475-83. PMID: 8914120.
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  217. McDougle CJ, Naylor ST, Cohen DJ, Aghajanian GK, Heninger GR, Price LH. Effects of tryptophan depletion in drug-free adults with autistic disorder. Arch Gen Psychiatry. 1996 Nov; 53(11):993-1000. PMID: 8911222.
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  218. Epperson CN, McDougle CJ, Price LH. Intranasal oxytocin in obsessive-compulsive disorder. Biol Psychiatry. 1996 Sep 15; 40(6):547-9. PMID: 8879477.
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  219. Epperson CN, McDougle CJ, Price LH. Intranasal oxytocin in trichotillomania. Biol Psychiatry. 1996 Sep 15; 40(6):559-60. PMID: 8879481.
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  220. Carpenter LL, McDougle CJ, Epperson CN, Price LH. A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder. Drug Saf. 1996 Aug; 15(2):116-34. PMID: 8884163.
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  221. McDougle CJ, Epperson CN, Price LH. Obsessive-compulsive symptoms with-neuroleptics. J Am Acad Child Adolesc Psychiatry. 1996 Jul; 35(7):837-8. PMID: 8768337.
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  222. Chappell P, Leckman J, Goodman W, Bissette G, Pauls D, Anderson G, Riddle M, Scahill L, McDougle C, Cohen D. Elevated cerebrospinal fluid corticotropin-releasing factor in Tourette's syndrome: comparison to obsessive compulsive disorder and normal controls. Biol Psychiatry. 1996 May 01; 39(9):776-83. PMID: 8731518.
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  223. Price LH, Malison RT, McDougle CJ, Pelton GH. Antiglucocorticoids as Treatments for Depression : Rationale for Use and Therapeutic Potential. CNS Drugs. 1996 May; 5(5):311-20. PMID: 26071044.
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  224. Kosten TR, Kosten TA, McDougle CJ, Hameedi FA, McCance EF, Rosen MI, Oliveto AH, Price LH. Gender differences in response to intranasal cocaine administration to humans. Biol Psychiatry. 1996 Jan 15; 39(2):147-8. PMID: 8717615.
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  225. Cappiello A, McDougle CJ, Malison RT, Heninger GR, Price LH. Yohimbine augmentation of fluvoxamine in refractory depression: a single-blind study. Biol Psychiatry. 1995 Dec 01; 38(11):765-7. PMID: 8580232.
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  226. McDougle CJ, Barr LC, Goodman WK, Pelton GH, Aronson SC, Anand A, Price LH. Lack of efficacy of clozapine monotherapy in refractory obsessive-compulsive disorder. Am J Psychiatry. 1995 Dec; 152(12):1812-4. PMID: 8526253.
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  227. McDougle CJ, Fleischmann RL, Epperson CN, Wasylink S, Leckman JF, Price LH. Risperidone addition in fluvoxamine-refractory obsessive-compulsive disorder: three cases. J Clin Psychiatry. 1995 Nov; 56(11):526-8. PMID: 7592506.
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  228. Malison RT, McDougle CJ, van Dyck CH, Scahill L, Baldwin RM, Seibyl JP, Price LH, Leckman JF, Innis RB. [123I]beta-CIT SPECT imaging of striatal dopamine transporter binding in Tourette's disorder. Am J Psychiatry. 1995 Sep; 152(9):1359-61. PMID: 7653693.
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  229. Lombroso PJ, Scahill L, King RA, Lynch KA, Chappell PB, Peterson BS, McDougle CJ, Leckman JF. Risperidone treatment of children and adolescents with chronic tic disorders: a preliminary report. J Am Acad Child Adolesc Psychiatry. 1995 Sep; 34(9):1147-52. PMID: 7559308.
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  230. Goodman WK, McDougle CJ, Price LH, Barr LC, Hills OF, Caplik JF, Charney DS, Heninger GR. m-Chlorophenylpiperazine in patients with obsessive-compulsive disorder: absence of symptom exacerbation. Biol Psychiatry. 1995 Aug 01; 38(3):138-49. PMID: 7578657.
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  231. Aronson SC, Black JE, McDougle CJ, Scanley BE, Jatlow P, Kosten TR, Heninger GR, Price LH. Serotonergic mechanisms of cocaine effects in humans. Psychopharmacology (Berl). 1995 May; 119(2):179-85. PMID: 7659765.
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  232. McDougle CJ, Kresch LE, Goodman WK, Naylor ST, Volkmar FR, Cohen DJ, Price LH. A case-controlled study of repetitive thoughts and behavior in adults with autistic disorder and obsessive-compulsive disorder. Am J Psychiatry. 1995 May; 152(5):772-7. PMID: 7726318.
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  233. Calvocoressi L, Lewis B, Harris M, Trufan SJ, Goodman WK, McDougle CJ, Price LH. Family accommodation in obsessive-compulsive disorder. Am J Psychiatry. 1995 Mar; 152(3):441-3. PMID: 7864273.
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  234. Anand A, Malison R, McDougle CJ, Price LH. Antiglucocorticoid treatment of refractory depression with ketoconazole: a case report. Biol Psychiatry. 1995 Mar 01; 37(5):338-40. PMID: 7748987.
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  235. McDougle CJ, Krystal JH, Price LH, Heninger GR, Charney DS. Noradrenergic response to acute ethanol administration in healthy subjects: comparison with intravenous yohimbine. Psychopharmacology (Berl). 1995 Mar; 118(2):127-35. PMID: 7617798.
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  236. Leckman JF, Goodman WK, Anderson GM, Riddle MA, Chappell PB, McSwiggan-Hardin MT, McDougle CJ, Scahill LD, Ort SI, Pauls DL, et al. Cerebrospinal fluid biogenic amines in obsessive compulsive disorder, Tourette's syndrome, and healthy controls. Neuropsychopharmacology. 1995 Feb; 12(1):73-86. PMID: 7766289.
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  237. Anand A, Charney DS, Delgado PL, McDougle CJ, Heninger GR, Price LH. Neuroendocrine and behavioral responses to intravenous m-chlorophenylpiperazine (mCPP) in depressed patients and healthy comparison subjects. Am J Psychiatry. 1994 Nov; 151(11):1626-30. PMID: 7943451.
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  238. Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM, Riddle MA, McSwiggan-Hardin M, McDougle CJ, et al. Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls. Arch Gen Psychiatry. 1994 Oct; 51(10):782-92. PMID: 7524462.
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  239. McDougle CJ, Black JE, Malison RT, Zimmermann RC, Kosten TR, Heninger GR, Price LH. Noradrenergic dysregulation during discontinuation of cocaine use in addicts. Arch Gen Psychiatry. 1994 Sep; 51(9):713-9. PMID: 8080348.
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  240. Barr LC, Goodman WK, McDougle CJ, Delgado PL, Heninger GR, Charney DS, Price LH. Tryptophan depletion in patients with obsessive-compulsive disorder who respond to serotonin reuptake inhibitors. Arch Gen Psychiatry. 1994 Apr; 51(4):309-17. PMID: 8161291.
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  241. Holzer JC, Goodman WK, McDougle CJ, Baer L, Boyarsky BK, Leckman JF, Price LH. Obsessive-compulsive disorder with and without a chronic tic disorder. A comparison of symptoms in 70 patients. Br J Psychiatry. 1994 Apr; 164(4):469-73. PMID: 8038934.
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  242. McDougle CJ, Goodman WK, Leckman JF, Lee NC, Heninger GR, Price LH. Haloperidol addition in fluvoxamine-refractory obsessive-compulsive disorder. A double-blind, placebo-controlled study in patients with and without tics. Arch Gen Psychiatry. 1994 Apr; 51(4):302-8. PMID: 8161290.
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  243. McDougle CJ, Goodman WK, Price LH. Dopamine antagonists in tic-related and psychotic spectrum obsessive compulsive disorder. J Clin Psychiatry. 1994 Mar; 55 Suppl:24-31. PMID: 7521326.
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  244. Leckman JF, Goodman WK, North WG, Chappell PB, Price LH, Pauls DL, Anderson GM, Riddle MA, McDougle CJ, Barr LC, et al. The role of central oxytocin in obsessive compulsive disorder and related normal behavior. Psychoneuroendocrinology. 1994; 19(8):723-49. PMID: 7991761.
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  245. Leckman JF, Grice DE, Barr LC, de Vries AL, Martin C, Cohen DJ, McDougle CJ, Goodman WK, Rasmussen SA. Tic-related vs. non-tic-related obsessive compulsive disorder. Anxiety. 1994-1995; 1(5):208-15. PMID: 9160576.
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  246. McDougle CJ, Goodman WK, Leckman JF, Price LH. The psychopharmacology of obsessive compulsive disorder. Implications for treatment and pathogenesis. Psychiatr Clin North Am. 1993 Dec; 16(4):749-66. PMID: 8309811.
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  247. McDougle CJ, Goodman WK, Leckman JF, Barr LC, Heninger GR, Price LH. The efficacy of fluvoxamine in obsessive-compulsive disorder: effects of comorbid chronic tic disorder. J Clin Psychopharmacol. 1993 Oct; 13(5):354-8. PMID: 8227493.
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  248. Sherman TL, McDougle CJ, Price LH. Paroxetine: a new serotonin reuptake inhibitor for the treatment of depression. Conn Med. 1993 Sep; 57(9):587-92. PMID: 8252846.
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  249. Goodman WK, McDougle CJ, Barr LC, Aronson SC, Price LH. Biological approaches to treatment-resistant obsessive compulsive disorder. J Clin Psychiatry. 1993 Jun; 54 Suppl:16-26. PMID: 8331098.
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  250. McDougle CJ, Goodman WK, Price LH. The pharmacotherapy of obsessive-compulsive disorder. Pharmacopsychiatry. 1993 May; 26 Suppl 1:24-9. PMID: 8378419.
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  251. Zimmermann RC, McDougle CJ, Schumacher M, Olcese J, Mason JW, Heninger GR, Price LH. Effects of acute tryptophan depletion on nocturnal melatonin secretion in humans. J Clin Endocrinol Metab. 1993 May; 76(5):1160-4. PMID: 8496306.
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  252. McDougle CJ, Naylor ST, Goodman WK, Volkmar FR, Cohen DJ, Price LH. Acute tryptophan depletion in autistic disorder: a controlled case study. Biol Psychiatry. 1993 Apr 01; 33(7):547-50. PMID: 8513041.
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  253. McDougle CJ, Goodman WK, Leckman JF, Holzer JC, Barr LC, McCance-Katz E, Heninger GR, Price LH. Limited therapeutic effect of addition of buspirone in fluvoxamine-refractory obsessive-compulsive disorder. Am J Psychiatry. 1993 Apr; 150(4):647-9. PMID: 8465885.
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  254. Rosen MI, Pearsall HR, McDougle CJ, Price LH, Woods SW, Kosten TR. Effects of acute buprenorphine on responses to intranasal cocaine: a pilot study. Am J Drug Alcohol Abuse. 1993; 19(4):451-64. PMID: 8273766.
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  255. Zimmermann RC, McDougle CJ, Schumacher M, Olcese J, Heninger GR, Price LH. Urinary 6-hydroxymelatonin sulfate as a measure of melatonin secretion during acute tryptophan depletion. Psychoneuroendocrinology. 1993; 18(8):567-78. PMID: 8127947.
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  256. McCance-Katz EF, Price LH, McDougle CJ, Kosten TR, Black JE, Jatlow PI. Concurrent cocaine-ethanol ingestion in humans: pharmacology, physiology, behavior, and the role of cocaethylene. Psychopharmacology (Berl). 1993; 111(1):39-46. PMID: 7870932.
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  257. McDougle CJ, Price LH, Palumbo JM, Kosten TR, Heninger GR, Kleber HD. Dopaminergic responsivity during cocaine abstinence: a pilot study. Psychiatry Res. 1992 Jul; 43(1):77-85. PMID: 1359594.
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  258. McDougle CJ, Price LH, Volkmar FR, Goodman WK, Ward-O'Brien D, Nielsen J, Bregman J, Cohen DJ. Clomipramine in autism: preliminary evidence of efficacy. J Am Acad Child Adolesc Psychiatry. 1992 Jul; 31(4):746-50. PMID: 1644740.
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  259. Goodman WK, McDougle CJ, Price LH. The role of serotonin and dopamine in the pathophysiology of obsessive compulsive disorder. Int Clin Psychopharmacol. 1992 Jun; 7 Suppl 1:35-8. PMID: 1517555.
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  260. Goodman WK, McDougle CJ, Price LH. Pharmacotherapy of obsessive compulsive disorder. J Clin Psychiatry. 1992 Apr; 53 Suppl:29-37. PMID: 1532962.
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  261. Barr LC, Goodman WK, Price LH, McDougle CJ, Charney DS. The serotonin hypothesis of obsessive compulsive disorder: implications of pharmacologic challenge studies. J Clin Psychiatry. 1992 Apr; 53 Suppl:17-28. PMID: 1532961.
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  262. Marek GJ, McDougle CJ, Price LH, Seiden LS. A comparison of trazodone and fluoxetine: implications for a serotonergic mechanism of antidepressant action. Psychopharmacology (Berl). 1992; 109(1-2):2-11. PMID: 1365657.
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  263. Krystal JH, McDougle CJ, Kosten TR, Price LH, Aghajanian GK, Charney DS. Baclofen-assisted detoxification from opiates. A pilot study. J Subst Abuse Treat. 1992; 9(2):139-42. PMID: 1324986.
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  264. Krystal JH, McDougle CJ, Woods SW, Price LH, Heninger GR, Charney DS. Dose-response relationship for oral idazoxan effects in healthy human subjects: comparison with oral yohimbine. Psychopharmacology (Berl). 1992; 108(3):313-9. PMID: 1355923.
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  265. Satel SL, Price LH, Palumbo JM, McDougle CJ, Krystal JH, Gawin F, Charney DS, Heninger GR, Kleber HD. Clinical phenomenology and neurobiology of cocaine abstinence: a prospective inpatient study. Am J Psychiatry. 1991 Dec; 148(12):1712-6. PMID: 1957935.
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  266. McDougle CJ, Southwick SM, Charney DS, St James RL. An open trial of fluoxetine in the treatment of posttraumatic stress disorder. J Clin Psychopharmacol. 1991 Oct; 11(5):325-7. PMID: 1765575.
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  267. Satel SL, McDougle CJ. Obsessions and compulsions associated with cocaine abuse. Am J Psychiatry. 1991 Jul; 148(7):947. PMID: 2053637.
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  268. McDougle CJ, Price LH, Goodman WK, Charney DS, Heninger GR. A controlled trial of lithium augmentation in fluvoxamine-refractory obsessive-compulsive disorder: lack of efficacy. J Clin Psychopharmacol. 1991 Jun; 11(3):175-84. PMID: 1820757.
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  269. Kosten TR, Frank JB, Dan E, McDougle CJ, Giller EL. Pharmacotherapy for posttraumatic stress disorder using phenelzine or imipramine. J Nerv Ment Dis. 1991 Jun; 179(6):366-70. PMID: 2051152.
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  270. Woods SW, O'Malley SS, Martini BL, McDougle CJ, Price LH, Krystal JH, Hoffer PB, Kosten TR. SPECT regional cerebral blood flow and neuropsychological testing in non-demented HIV-positive drug abusers: preliminary results. Prog Neuropsychopharmacol Biol Psychiatry. 1991; 15(5):649-62. PMID: 1956993.
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  271. McDougle CJ, Price LH, Goodman WK. Fluvoxamine treatment of coincident autistic disorder and obsessive-compulsive disorder: a case report. J Autism Dev Disord. 1990 Dec; 20(4):537-43. PMID: 2126264.
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  272. Goodman WK, McDougle CJ, Price LH, Riddle MA, Pauls DL, Leckman JF. Beyond the serotonin hypothesis: a role for dopamine in some forms of obsessive compulsive disorder? J Clin Psychiatry. 1990 Aug; 51 Suppl:36-43; discussion 55-8. PMID: 2199433.
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  273. McDougle CJ, Goodman WK, Price LH, Delgado PL, Krystal JH, Charney DS, Heninger GR. Neuroleptic addition in fluvoxamine-refractory obsessive-compulsive disorder. Am J Psychiatry. 1990 May; 147(5):652-4. PMID: 1970224.
    View in: PubMed
  274. McDougle CJ, Southwick SM. Emergence of an alternate personality in combat-related posttraumatic stress disorder. Hosp Community Psychiatry. 1990 May; 41(5):554-6. PMID: 2347575.
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  275. McDougle CJ, Southwick SM, Rohrbaugh RM. Tourette's disorder and associated complex behaviors: a case report. Yale J Biol Med. 1990 May-Jun; 63(3):209-14. PMID: 2238716; PMCID: PMC2589286.
  276. McDougle CJ, Goodman WK, Delgado PL, Price LH. Pathophysiology of obsessive-compulsive disorder. Am J Psychiatry. 1989 Oct; 146(10):1350-1. PMID: 2782483.
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  277. McDougle CJ, Milstein V. MHPG, ECT, and depression. Biol Psychiatry. 1985 Aug; 20(8):927. PMID: 4027307.
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