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Last Name

profileMohan K Malleshaiah, Ph.D.

TitleResearch Fellow in Systems Biology (INT)
InstitutionHarvard Medical School
DepartmentSystems Biology
AddressHarvard Medical School
Systems Biology WAB 5366
200 Longwood Ave
Boston MA 02115
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  1. Sugimura R, Jha DK, Han A, Soria-Valles C, da Rocha EL, Lu YF, Goettel JA, Serrao E, Rowe RG, Malleshaiah M, Wong I, Sousa P, Zhu TN, Ditadi A, Keller G, Engelman AN, Snapper SB, Doulatov S, Daley GQ. Haematopoietic stem and progenitor cells from human pluripotent stem cells. Nature. 2017 05 25; 545(7655):432-438. PMID: 28514439.
    View in: PubMed
  2. Michnick SW, Landry CR, Levy ED, Diss G, Ear PH, Kowarzyk J, Malleshaiah MK, Messier V, Tchekanda E. Protein-Fragment Complementation Assays for Large-Scale Analysis, Functional Dissection, and Spatiotemporal Dynamic Studies of Protein-Protein Interactions in Living Cells. Cold Spring Harb Protoc. 2016 Nov 01; 2016(11):pdb.top083543. PMID: 27803260.
    View in: PubMed
  3. Malleshaiah M, Tchekanda E, Michnick SW. Real-Time Protein-Fragment Complementation Assays for Studying Temporal, Spatial, and Spatiotemporal Dynamics of Protein-Protein Interactions in Living Cells. Cold Spring Harb Protoc. 2016 Nov 01; 2016(11):pdb.prot090068. PMID: 27803255.
    View in: PubMed
  4. Malleshaiah M, Padi M, Rué P, Quackenbush J, Martinez-Arias A, Gunawardena J. Nac1 Coordinates a Sub-network of Pluripotency Factors to Regulate Embryonic Stem Cell Differentiation. Cell Rep. 2016 Feb 09; 14(5):1181-94. PMID: 26832399; PMCID: PMC4749452.
  5. Malleshaiah M, Gunawardena J. Cybernetics, Redux: An Outside-In Strategy for Unraveling Cellular Function. Dev Cell. 2016 Jan 11; 36(1):2-4. PMID: 26766437.
    View in: PubMed
  6. Röck R, Bachmann V, Bhang HE, Malleshaiah M, Raffeiner P, Mayrhofer JE, Tschaikner PM, Bister K, Aanstad P, Pomper MG, Michnick SW, Stefan E. In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs. Sci Rep. 2015 Jun 23; 5:11133. PMID: 26099953; PMCID: PMC4477410.
  7. Stefan E, Malleshaiah MK, Breton B, Ear PH, Bachmann V, Beyermann M, Bouvier M, Michnick SW. PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades. Nat Commun. 2011 Dec 20; 2:598. PMID: 22186894; PMCID: PMC3247815.
  8. Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V. Protein-fragment complementation assays for large-scale analysis, functional dissection and dynamic studies of protein-protein interactions in living cells. Methods Mol Biol. 2011; 756:395-425. PMID: 21870242.
    View in: PubMed
  9. Malleshaiah MK, Shahrezaei V, Swain PS, Michnick SW. The scaffold protein Ste5 directly controls a switch-like mating decision in yeast. Nature. 2010 May 06; 465(7294):101-5. PMID: 20400943.
    View in: PubMed
  10. Michnick SW, Ear PH, Landry C, Malleshaiah MK, Messier V. A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein-protein interactions in living cells. Methods Enzymol. 2010; 470:335-68. PMID: 20946817.
    View in: PubMed
  11. Manderson EN, Malleshaiah M, Michnick SW. A novel genetic screen implicates Elm1 in the inactivation of the yeast transcription factor SBF. PLoS One. 2008 Jan 30; 3(1):e1500. PMID: 18231587; PMCID: PMC2198942.
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