Harvard Catalyst Profiles

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Amber Dahlin, Ph.D.

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Other Positions

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL152244 (DAHLIN, AMBER) Jun 1, 2020 - Apr 30, 2025
    Pharmacogenomics of Adrenal Suppression with Inhaled Corticosteroids (PhASIC)
    Role: Principal Investigator
  2. K01HL130629 (DAHLIN, AMBER) Jul 15, 2016 - Apr 30, 2021
    Role of microRNA molecules in therapeutic response to leukotriene modifying agents in asthma
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kachroo P, Stewart ID, Kelly RS, Stav M, Mendez K, Dahlin A, Soeteman DI, Chu SH, Huang M, Cote M, Knihtilä HM, Lee-Sarwar K, McGeachie M, Wang A, Wu AC, Virkud Y, Zhang P, Wareham NJ, Karlson EW, Wheelock CE, Clish C, Weiss ST, Langenberg C, Lasky-Su JA. Author Correction: Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma. Nat Med. 2022 Aug; 28(8):1723. PMID: 35859205.
    Citations:    Fields:    
  2. Wang AL, Lahousse L, Dahlin A, Edris A, McGeachie M, Lutz SM, Sordillo JE, Brusselle G, Lasky-Su J, Weiss ST, Iribarren C, Lu MX, Tantisira KG, Wu AC. Novel genetic variants associated with inhaled corticosteroid treatment response in older adults with asthma. Thorax. 2022 May 02. PMID: 35501119.
    Citations:    Fields:    
  3. Kachroo P, Stewart ID, Kelly RS, Stav M, Mendez K, Dahlin A, Soeteman DI, Chu SH, Huang M, Cote M, Knihtilä HM, Lee-Sarwar K, McGeachie M, Wang A, Wu AC, Virkud Y, Zhang P, Wareham NJ, Karlson EW, Wheelock CE, Clish C, Weiss ST, Langenberg C, Lasky-Su JA. Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma. Nat Med. 2022 04; 28(4):814-822. PMID: 35314841; PMCID: PMC9350737.
    Citations:    Fields:    Translation:Humans
  4. Sordillo JE, Lutz SM, Jorgenson E, Iribarren C, McGeachie M, Dahlin A, Tantisira K, Kelly R, Lasky-Su J, Sakornsakolpat P, Moll M, Cho MH, Wu AC. A polygenic risk score for asthma in a large racially diverse population. Clin Exp Allergy. 2021 11; 51(11):1410-1420. PMID: 34459047; PMCID: PMC8551047.
    Citations:    Fields:    Translation:Humans
  5. Wu AC, Dahlin A, Wang AL. The Role of Environmental Risk Factors on the Development of Childhood Allergic Rhinitis. Children (Basel). 2021 Aug 17; 8(8). PMID: 34438599; PMCID: PMC8391414.
    Citations: 1     
  6. Voorhies K, Sordillo JE, McGeachie M, Ampleford E, Wang AL, Lasky-Su J, Tantisira K, Dahlin A, Kelly RS, Ortega VE, Lutz SM, Wu AC. Age by Single Nucleotide Polymorphism Interactions on Bronchodilator Response in Asthmatics. J Pers Med. 2021 Jan 19; 11(1). PMID: 33477890; PMCID: PMC7833432.
    Citations: 2     
  7. Tian L, Wang XW, Wu AK, Fan Y, Friedman J, Dahlin A, Waldor MK, Weinstock GM, Weiss ST, Liu YY. Deciphering functional redundancy in the human microbiome. Nat Commun. 2020 12 04; 11(1):6217. PMID: 33277504.
    Citations: 27     Fields:    Translation:HumansCells
  8. Dahlin A, Sordillo JE, McGeachie M, Kelly RS, Tantisira KG, Lutz SM, Lasky-Su J, Wu AC. Genome-wide interaction study reveals age-dependent determinants of responsiveness to inhaled corticosteroids in individuals with asthma. PLoS One. 2020; 15(3):e0229241. PMID: 32119686; PMCID: PMC7051058.
    Citations: 7     Fields:    Translation:Humans
  9. Sordillo JE, Lutz SM, Kelly RS, McGeachie MJ, Dahlin A, Tantisira K, Clish C, Lasky-Su J, Wu AC. Plasmalogens Mediate the Effect of Age on Bronchodilator Response in Individuals With Asthma. Front Med (Lausanne). 2020; 7:38. PMID: 32118022.
    Citations: 3     
  10. McGeachie MJ, Sordillo JE, Dahlin A, Wang AL, Lutz SM, Tantisira KG, Panganiban R, Lu Q, Sajuthi S, Urbanek C, Kelly R, Saef B, Eng C, Oh SS, Kho AT, Croteau-Chonka DC, Weiss ST, Raby BA, Mak ACY, Rodriguez-Santana JR, Burchard EG, Seibold MA, Wu AC. Expression of SMARCD1 interacts with age in association with asthma control on inhaled corticosteroid therapy. Respir Res. 2020 Jan 28; 21(1):31. PMID: 31992292; PMCID: PMC6988322.
    Citations:    Fields:    Translation:Humans
  11. Kelly RS, Sordillo JE, Lutz SM, Avila L, Soto-Quiros M, Celedón JC, McGeachie MJ, Dahlin A, Tantisira K, Huang M, Clish CB, Weiss ST, Lasky-Su J, Wu AC. Pharmacometabolomics of Bronchodilator Response in Asthma and the Role of Age-Metabolite Interactions. Metabolites. 2019 Sep 07; 9(9). PMID: 31500319; PMCID: PMC6780678.
    Citations: 6     
  12. Park HW, Dahlin A, Qiu W, Tantisira KG. Gene expression changes in lymphoblastoid cell lines and primary B cells by dexamethasone. Pharmacogenet Genomics. 2019 04; 29(3):58-64. PMID: 30562215; PMCID: PMC7172499.
    Citations: 3     Fields:    Translation:HumansCells
  13. Sordillo JE, McGeachie M, Lutz SM, Lasky-Su J, Tantisira K, Tsai CH, Dahlin A, Kelly R, Wu AC. Longitudinal analysis of bronchodilator response in asthmatics and effect modification of age-related trends by genotype. Pediatr Pulmonol. 2019 02; 54(2):158-164. PMID: 30585438.
    Citations: 9     Fields:    Translation:Humans
  14. Dahlin A, Sordillo JE, Ziniti J, Iribarren C, Lu M, Weiss ST, Tantisira KG, Lu Q, Kan M, Himes BE, Jorgenson E, Wu AC. Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults. J Allergy Clin Immunol. 2019 04; 143(4):1633-1635. PMID: 30578877; PMCID: PMC6451881.
    Citations: 12     Fields:    Translation:Humans
  15. Virkud YV, Kelly RS, Croteau-Chonka DC, Celedón JC, Dahlin A, Avila L, Raby BA, Weiss ST, Lasky-Su JA. Novel eosinophilic gene expression networks associated with IgE in two distinct asthma populations. Clin Exp Allergy. 2018 12; 48(12):1654-1664. PMID: 30107053; PMCID: PMC6659730.
    Citations: 10     Fields:    Translation:HumansCells
  16. Kelly RS, Sordillo JE, Lasky-Su J, Dahlin A, Perng W, Rifas-Shiman SL, Weiss ST, Gold DR, Litonjua AA, Hivert MF, Oken E, Wu AC. Plasma metabolite profiles in children with current asthma. Clin Exp Allergy. 2018 10; 48(10):1297-1304. PMID: 29808611; PMCID: PMC6160355.
    Citations: 18     Fields:    Translation:Humans
  17. Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG. Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma. Am J Respir Crit Care Med. 2018 06 15; 197(12):1552-1564. PMID: 29509491; PMCID: PMC6006403.
    Citations: 49     Fields:    Translation:Humans
  18. Panganiban RA, Sun M, Dahlin A, Park HR, Kan M, Himes BE, Mitchel JA, Iribarren C, Jorgenson E, Randell SH, Israel E, Tantisira K, Shore S, Park JA, Weiss ST, Wu AC, Lu Q. A functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis. J Allergy Clin Immunol. 2018 11; 142(5):1469-1478.e2. PMID: 29330013; PMCID: PMC6037620.
    Citations: 46     Fields:    Translation:HumansCells
  19. Dahlin A, Qiu W, Litonjua AA, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Wu AC, Weiss ST, Tantisira KG. The phosphatidylinositide 3-kinase (PI3K) signaling pathway is a determinant of zileuton response in adults with asthma. Pharmacogenomics J. 2018 09; 18(5):665-677. PMID: 29298996; PMCID: PMC6150906.
    Citations: 3     Fields:    Translation:HumansCells
  20. Jiang X, Dahlin A, Weiss ST, Tantisira K, Lu Q. A high-throughput chemical screen identifies novel inhibitors and enhancers of anti-inflammatory functions of the glucocorticoid receptor. Sci Rep. 2017 08 07; 7(1):7405. PMID: 28785063.
    Citations: 5     Fields:    Translation:HumansCells
  21. Lasky-Su J, Dahlin A, Litonjua AA, Rogers AJ, McGeachie MJ, Baron RM, Gazourian L, Barragan-Bradford D, Fredenburgh LE, Choi AMK, Mogensen KM, Quraishi SA, Amrein K, Christopher KB. Metabolome alterations in severe critical illness and vitamin D status. Crit Care. 2017 07 28; 21(1):193. PMID: 28750641.
    Citations: 16     Fields:    Translation:Humans
  22. McGeachie MJ, Davis JS, Kho AT, Dahlin A, Sordillo JE, Sun M, Lu Q, Weiss ST, Tantisira KG. Asthma remission: Predicting future airways responsiveness using an miRNA network. J Allergy Clin Immunol. 2017 08; 140(2):598-600.e8. PMID: 28238746; PMCID: PMC5546990.
    Citations: 13     Fields:    Translation:Humans
  23. Kelly RS, Croteau-Chonka DC, Dahlin A, Mirzakhani H, Wu AC, Wan ES, McGeachie MJ, Qiu W, Sordillo JE, Al-Garawi A, Gray KJ, McElrath TF, Carey VJ, Clish CB, Litonjua AA, Weiss ST, Lasky-Su JA. Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia. Metabolomics. 2017 Jan; 13(1). PMID: 28596717; PMCID: PMC5458629.
    Citations: 24     Fields:    
  24. Dahlin A, Weiss ST. Genetic and Epigenetic Components of Aspirin-Exacerbated Respiratory Disease. Immunol Allergy Clin North Am. 2016 11; 36(4):765-789. PMID: 27712769.
    Citations: 7     Fields:    Translation:HumansCells
  25. Kelly RS, Dahlin A, McGeachie MJ, Qiu W, Sordillo J, Wan ES, Wu AC, Lasky-Su J. Asthma Metabolomics and the Potential for Integrative Omics in Research and the Clinic. Chest. 2017 Feb; 151(2):262-277. PMID: 27776981; PMCID: PMC5310123.
    Citations: 71     Fields:    Translation:HumansCells
  26. Amber Dahlin, Kelan Tantisira. Pharmacogenomics. Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy. 2016.
  27. Dahlin A, Denny J, Roden DM, Brilliant MH, Ingram C, Kitchner TE, Linneman JG, Shaffer CM, Weeke P, Xu H, Kubo M, Tamari M, Clemmer GL, Ziniti J, McGeachie MJ, Tantisira KG, Weiss ST, Wu AC. CMTR1 is associated with increased asthma exacerbations in patients taking inhaled corticosteroids. Immun Inflamm Dis. 2015 Dec; 3(4):350-9. PMID: 26734457.
    Citations: 18     Fields:    
  28. Dahlin A, Litonjua A, Lima JJ, Tamari M, Kubo M, Irvin CG, Peters SP, Tantisira KG. Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma. PLoS One. 2015; 10(6):e0129385. PMID: 26083242; PMCID: PMC4470685.
    Citations: 8     Fields:    Translation:Humans
  29. Dahlin A, Litonjua A, Irvin CG, Peters SP, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genome-wide association study of leukotriene modifier response in asthma. Pharmacogenomics J. 2016 Apr; 16(2):151-7. PMID: 26031901; PMCID: PMC4668236.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  30. McGeachie MJ, Dahlin A, Qiu W, Croteau-Chonka DC, Savage J, Wu AC, Wan ES, Sordillo JE, Al-Garawi A, Martinez FD, Strunk RC, Lemanske RF, Liu AH, Raby BA, Weiss S, Clish CB, Lasky-Su JA. The metabolomics of asthma control: a promising link between genetics and disease. Immun Inflamm Dis. 2015 Sep; 3(3):224-38. PMID: 26421150; PMCID: PMC4578522.
    Citations: 37     Fields:    
  31. Dahlin A, Wittwer M, de la Cruz M, Woo JM, Bam R, Scharen-Guivel V, Flaherty J, Ray AS, Cihlar T, Gupta SK, Giacomini KM. A pharmacogenetic candidate gene study of tenofovir-associated Fanconi syndrome. Pharmacogenet Genomics. 2015 Feb; 25(2):82-92. PMID: 25485598; PMCID: PMC4331349.
    Citations: 9     Fields:    Translation:HumansCells
  32. Dahlin A, McGeachie MJ, Lasky-Su JA . Asthma Metabolomics: The Missing Step for Translating Bench Work into the Clinic. J Pulm Respir Med. 2015; 267(5).
  33. McGeachie MJ, Clemmer GL, Lasky-Su J, Dahlin A, Raby BA, Weiss ST. Joint GWAS Analysis: Comparing similar GWAS at different genomic resolutions identifies novel pathway associations with six complex diseases. Genom Data. 2014 Dec 01; 2:202-211. PMID: 25838990; PMCID: PMC4378545.
    Citations: 6     
  34. Park HW, Dahlin A, Tse S, Duan QL, Schuemann B, Martinez FD, Peters SP, Szefler SJ, Lima JJ, Kubo M, Tamari M, Tantisira KG. Genetic predictors associated with improvement of asthma symptoms in response to inhaled corticosteroids. J Allergy Clin Immunol. 2014 Mar; 133(3):664-9.e5. PMID: 24486069; PMCID: PMC4112383.
    Citations: 28     Fields:    Translation:Humans
  35. Dahlin A, Geier E, Stocker SL, Cropp CD, Grigorenko E, Bloomer M, Siegenthaler J, Xu L, Basile AS, Tang-Liu DD, Giacomini KM. Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures. Mol Pharm. 2013 Feb 04; 10(2):650-63. PMID: 23268600.
    Citations: 18     Fields:    Translation:Humans
  36. Stocker SL, Morrissey KM, Yee SW, Castro RA, Xu L, Dahlin A, Ramirez AH, Roden DM, Wilke RA, McCarty CA, Davis RL, Brett CM, Giacomini KM. The effect of novel promoter variants in MATE1 and MATE2 on the pharmacokinetics and pharmacodynamics of metformin. Clin Pharmacol Ther. 2013 Feb; 93(2):186-94. PMID: 23267855; PMCID: PMC3671611.
    Citations: 65     Fields:    Translation:Humans
  37. Dahlin A, Tantisira KG. Integrative systems biology approaches in asthma pharmacogenomics. Pharmacogenomics. 2012 Sep; 13(12):1387-404. PMID: 22966888.
    Citations: 8     Fields:    Translation:HumansAnimals
  38. Schlessinger A, Wittwer MB, Dahlin A, Khuri N, Bonomi M, Fan H, Giacomini KM, Sali A. High selectivity of the ?-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach. J Biol Chem. 2012 Nov 02; 287(45):37745-56. PMID: 22932902.
    Citations: 20     Fields:    Translation:HumansCells
  39. Ho HT, Dahlin A, Wang J. Expression Profiling of Solute Carrier Gene Families at the Blood-CSF Barrier. Front Pharmacol. 2012; 3:154. PMID: 22936914.
    Citations: 23     
  40. Giacomini KM, Huang SM, Tweedie DJ, Benet LZ, Brouwer KL, Chu X, Dahlin A, Evers R, Fischer V, Hillgren KM, Hoffmaster KA, Ishikawa T, Keppler D, Kim RB, Lee CA, Niemi M, Polli JW, Sugiyama Y, Swaan PW, Ware JA, Wright SH, Yee SW, Zamek-Gliszczynski MJ, Zhang L. Membrane transporters in drug development. Nat Rev Drug Discov. 2010 Mar; 9(3):215-36. PMID: 20190787.
    Citations: 884     Fields:    Translation:HumansAnimals
  41. Dahlin A, Royall J, Hohmann JG, Wang J. Expression profiling of the solute carrier gene family in the mouse brain. J Pharmacol Exp Ther. 2009 May; 329(2):558-70. PMID: 19179540.
    Citations: 47     Fields:    Translation:AnimalsCells
  42. Dahlin A, Xia L, Kong W, Hevner R, Wang J. Expression and immunolocalization of the plasma membrane monoamine transporter in the brain. Neuroscience. 2007 May 25; 146(3):1193-211. PMID: 17408864.
    Citations: 61     Fields:    Translation:AnimalsCells
  43. Unadkat JD, Dahlin A, Vijay S. Placental drug transporters. Curr Drug Metab. 2004 Feb; 5(1):125-31. PMID: 14965255.
    Citations: 20     Fields:    Translation:Humans
  44. Disis ML, Scholler N, Dahlin A, Pullman J, Knutson KL, Hellström KE, Hellström I. Plasmid-based vaccines encoding rat neu and immune stimulatory molecules can elicit rat neu-specific immunity. Mol Cancer Ther. 2003 Oct; 2(10):995-1002. PMID: 14578464.
    Citations: 5     Fields:    Translation:AnimalsCells
  45. Ye Z, Hellström I, Hayden-Ledbetter M, Dahlin A, Ledbetter JA, Hellström KE. Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB. Nat Med. 2002 Apr; 8(4):343-8. PMID: 11927939.
    Citations: 41     Fields:    Translation:HumansAnimalsCells
  46. Scholler N, Hayden-Ledbetter M, Dahlin A, Hellström I, Hellström KE, Ledbetter JA. Cutting edge: CD83 regulates the development of cellular immunity. J Immunol. 2002 Mar 15; 168(6):2599-602. PMID: 11884422.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.