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Elena Crestani, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Benamar M, Harb H, Chen Q, Wang M, Chan TMF, Fong J, Phipatanakul W, Cunningham A, Ertem D, Petty CR, Mousavi AJ, Sioutas C, Crestani E, Chatila TA. A common IL-4 receptor variant promotes asthma severity via a Treg cell GRB2-IL-6-Notch4 circuit. Allergy. 2022 Jul 16. PMID: 35841382.
    Citations:    Fields:    
  2. Banzon TM, Kelly MS, Bartnikas LM, Sheehan WJ, Cunningham A, Harb H, Crestani E, Valeri L, Greco KF, Chatila TA, Phipatanakul W, Lai PS. Atopic Dermatitis Mediates the Association Between an IL4RA Variant and Food Allergy in School-Aged Children. J Allergy Clin Immunol Pract. 2022 08; 10(8):2117-2124.e4. PMID: 35589010.
    Citations:    Fields:    
  3. Chatila TA, Benamar M, Chen Q, Chou J, Julé A, Boudra R, Contini P, Crestani E, Wang M, Fong J, Lai P, Rockwitz S, Lee P, Chan TMF, Altun EZ, Kepenekli E, Karakoc-Aydiner E, Ozen A, Boran P, Aygun F, Onal P, Sakalli AAK, Cokugras H, Gelmez M, Öktelik F, Cetin EA, Zhong Y, Taylor M, Irby K, Halasa N, Signa S, Prigione I, Gattorno M, Cotugno N, Amodio D, Geha R, Son MB, Newburger J, Agrawal P, Volpi S, Palma P, Kiykim A, Randolph A, Deniz G, Baris S, De Palma R, Schmitz-Abe K, Charbonnier LM, Henderson L. Notch1-CD22-Dependent Immune Dysregulation in the SARS-CoV2-Associated Multisystem Inflammatory Syndrome in Children. Res Sq. 2022 Apr 11. PMID: 35441180; PMCID: PMC9016654.
    Citations:    
  4. Leon J, Michelson DA, Olejnik J, Chowdhary K, Oh HS, Hume AJ, Galván-Peña S, Zhu Y, Chen F, Vijaykumar B, Yang L, Crestani E, Yonker LM, Knipe DM, Mühlberger E, Benoist C. A virus-specific monocyte inflammatory phenotype is induced by SARS-CoV-2 at the immune-epithelial interface. Proc Natl Acad Sci U S A. 2022 01 04; 119(1). PMID: 34969849; PMCID: PMC8740714.
    Citations:    Fields:    Translation:HumansCells
  5. Harb H, Stephen-Victor E, Crestani E, Benamar M, Massoud A, Cui Y, Charbonnier LM, Arbag S, Baris S, Cunnigham A, Leyva-Castillo JM, Geha RS, Mousavi AJ, Guennewig B, Schmitz-Abe K, Sioutas C, Phipatanakul W, Chatila TA. Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nat Immunol. 2021 Jun; 22(6):794-795. PMID: 33903767.
    Citations:    Fields:    
  6. Harb H, Benamar M, Lai PS, Contini P, Griffith JW, Crestani E, Schmitz-Abe K, Chen Q, Fong J, Marri L, Filaci G, Del Zotto G, Pishesha N, Kolifrath S, Broggi A, Ghosh S, Gelmez MY, Oktelik FB, Cetin EA, Kiykim A, Kose M, Wang Z, Cui Y, Yu XG, Li JZ, Berra L, Stephen-Victor E, Charbonnier LM, Zanoni I, Ploegh H, Deniz G, De Palma R, Chatila TA. Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections. Immunity. 2021 06 08; 54(6):1186-1199.e7. PMID: 33915108.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  7. Harb H, Stephen-Victor E, Crestani E, Benamar M, Massoud A, Cui Y, Charbonnier LM, Arbag S, Baris S, Cunnigham A, Leyva-Castillo JM, Geha RS, Mousavi AJ, Guennewig B, Schmitz-Abe K, Sioutas C, Phipatanakul W, Chatila TA. Author Correction: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nat Immunol. 2021 Jan; 22(1):100. PMID: 33214720.
    Citations:    Fields:    
  8. Turner JA, Stephen-Victor E, Wang S, Rivas MN, Abdel-Gadir A, Harb H, Cui Y, Fanny M, Charbonnier LM, Hung Fong JJ, Benamar M, Wang L, Burton OT, Bansal K, Bry L, Zhu C, Li QZ, Clement RL, Oettgen HC, Crestani E, Rachid R, Sage PT, Chatila TA. Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Immunity. 2020 Dec 15; 53(6):1331-1332. PMID: 33326768.
    Citations: 3     Fields:    
  9. Turner JA, Stephen-Victor E, Wang S, Rivas MN, Abdel-Gadir A, Harb H, Cui Y, Fanny M, Charbonnier LM, Fong JJH, Benamar M, Wang L, Burton OT, Bansal K, Bry L, Zhu C, Li QZ, Clement RL, Oettgen HC, Crestani E, Rachid R, Sage PT, Chatila TA. Regulatory T Cell-Derived TGF-ß1 Controls Multiple Checkpoints Governing Allergy and Autoimmunity. Immunity. 2020 12 15; 53(6):1202-1214.e6. PMID: 33086036; PMCID: PMC7744401.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  10. Broyles AD, Banerji A, Barmettler S, Biggs CM, Blumenthal K, Brennan PJ, Breslow RG, Brockow K, Buchheit KM, Cahill KN, Cernadas J, Chiriac AM, Crestani E, Demoly P, Dewachter P, Dilley M, Farmer JR, Foer D, Fried AJ, Garon SL, Giannetti MP, Hepner DL, Hong DI, Hsu JT, Kothari PH, Kyin T, Lax T, Lee MJ, Lee-Sarwar K, Liu A, Logsdon S, Louisias M, MacGinnitie A, Maciag M, Minnicozzi S, Norton AE, Otani IM, Park M, Patil S, Phillips EJ, Picard M, Platt CD, Rachid R, Rodriguez T, Romano A, Stone CA, Torres MJ, Verdú M, Wang AL, Wickner P, Wolfson AR, Wong JT, Yee C, Zhou J, Castells M. Practical Guidance for the Evaluation and Management of Drug Hypersensitivity: Specific Drugs. J Allergy Clin Immunol Pract. 2020 10; 8(9S):S16-S116. PMID: 33039007.
    Citations: 28     Fields:    Translation:Humans
  11. Harb H, Stephen-Victor E, Crestani E, Benamar M, Massoud A, Cui Y, Charbonnier LM, Arbag S, Baris S, Cunnigham A, Leyva-Castillo JM, Geha RS, Mousavi AJ, Guennewig B, Schmitz-Abe K, Sioutas C, Phipatanakul W, Chatila TA. A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma. Nat Immunol. 2020 11; 21(11):1359-1370. PMID: 32929274; PMCID: PMC7578174.
    Citations: 24     Fields:    Translation:HumansCells
  12. Stephen-Victor E, Crestani E, Chatila TA. Dietary and Microbial Determinants in Food Allergy. Immunity. 2020 08 18; 53(2):277-289. PMID: 32814026.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  13. Crestani E, Harb H, Charbonnier LM, Leirer J, Motsinger-Reif A, Rachid R, Phipatanakul W, Kaddurah-Daouk R, Chatila TA. Untargeted metabolomic profiling identifies disease-specific signatures in food allergy and asthma. J Allergy Clin Immunol. 2020 03; 145(3):897-906. PMID: 31669435; PMCID: PMC7062570.
    Citations: 28     Fields:    Translation:Humans
  14. Abdel-Gadir A, Stephen-Victor E, Gerber GK, Noval Rivas M, Wang S, Harb H, Wang L, Li N, Crestani E, Spielman S, Secor W, Biehl H, DiBenedetto N, Dong X, Umetsu DT, Bry L, Rachid R, Chatila TA. Author Correction: Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. Nat Med. 2019 Sep; 25(9):1458. PMID: 31420602.
    Citations: 2     Fields:    
  15. Bosticardo M, Yamazaki Y, Cowan J, Giardino G, Corsino C, Scalia G, Prencipe R, Ruffner M, Hill DA, Sakovich I, Yemialyanava I, Tam JS, Padem N, Elder ME, Sleasman JW, Perez E, Niebur H, Seroogy CM, Sharapova S, Gebbia J, Kleiner GI, Peake J, Abbott JK, Gelfand EW, Crestani E, Biggs C, Butte MJ, Hartog N, Hayward A, Chen K, Heimall J, Seeborg F, Bartnikas LM, Cooper MA, Pignata C, Bhandoola A, Notarangelo LD. Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis. Am J Hum Genet. 2019 09 05; 105(3):549-561. PMID: 31447097; PMCID: PMC6731368.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  16. Abdel-Gadir A, Stephen-Victor E, Gerber GK, Noval Rivas M, Wang S, Harb H, Wang L, Li N, Crestani E, Spielman S, Secor W, Biehl H, DiBenedetto N, Dong X, Umetsu DT, Bry L, Rachid R, Chatila TA. Microbiota therapy acts via a regulatory T cell MyD88/ROR?t pathway to suppress food allergy. Nat Med. 2019 07; 25(7):1164-1174. PMID: 31235962.
    Citations: 85     Fields:    Translation:AnimalsCells
  17. Albuhairi S, Sare T, Lakin P, El Khoury K, Crestani E, Schneider LC, Anzaldi R, Patterson A, Rachid R. Systemic Reactions in Pediatric Patients Receiving Standardized Allergen Subcutaneous Immunotherapy with and without Seasonal Dose Adjustment. J Allergy Clin Immunol Pract. 2018 Sep - Oct; 6(5):1711-1716.e4. PMID: 29339129.
    Citations:    Fields:    Translation:Humans
  18. Bird JA, Spergel JM, Jones SM, Rachid R, Assa'ad AH, Wang J, Leonard SA, Laubach SS, Kim EH, Vickery BP, Davis BP, Heimall J, Cianferoni A, MacGinnitie AJ, Crestani E, Burks AW. Efficacy and Safety of AR101 in Oral Immunotherapy for Peanut Allergy: Results of ARC001, a Randomized, Double-Blind, Placebo-Controlled Phase 2 Clinical Trial. J Allergy Clin Immunol Pract. 2018 Mar - Apr; 6(2):476-485.e3. PMID: 29092786.
    Citations: 40     Fields:    Translation:HumansAnimalsCTClinical Trials
  19. Wang Y, Ma CS, Ling Y, Bousfiha A, Camcioglu Y, Jacquot S, Payne K, Crestani E, Roncagalli R, Belkadi A, Kerner G, Lorenzo L, Deswarte C, Chrabieh M, Patin E, Vincent QB, Müller-Fleckenstein I, Fleckenstein B, Ailal F, Quintana-Murci L, Fraitag S, Alyanakian MA, Leruez-Ville M, Picard C, Puel A, Bustamante J, Boisson-Dupuis S, Malissen M, Malissen B, Abel L, Hovnanian A, Notarangelo LD, Jouanguy E, Tangye SG, Béziat V, Casanova JL. Dual T cell- and B cell-intrinsic deficiency in humans with biallelic RLTPR mutations. J Exp Med. 2016 10 17; 213(11):2413-2435. PMID: 27647349.
    Citations: 44     Fields:    Translation:HumansCells
  20. Sobh A, Crestani E, Cangemi B, Kane J, Chou J, Pai SY, Notarangelo LD, Al-Herz W, Geha RS, Massaad MJ. Autoimmune lymphoproliferative syndrome caused by a homozygous FasL mutation that disrupts FasL assembly. J Allergy Clin Immunol. 2016 Jan; 137(1):324-327.e2. PMID: 26456038.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  21. Crestani E, Volpi S, Candotti F, Giliani S, Notarangelo LD, Chu J, Aldave Becerra JC, Buchbinder D, Chou J, Geha RS, Kanariou M, King A, Mazza C, Moratto D, Sokolic R, Garabedian E, Porta F, Putti MC, Wakim RH, Tsitsikov E, Pai SY, Notarangelo LD. Broad spectrum of autoantibodies in patients with Wiskott-Aldrich syndrome and X-linked thrombocytopenia. J Allergy Clin Immunol. 2015 Nov; 136(5):1401-4.e1-3. PMID: 26409660; PMCID: PMC4640933.
    Citations: 14     Fields:    Translation:Humans
  22. Kato T, Crestani E, Kamae C, Honma K, Yokosuka T, Ikegawa T, Nishida N, Kanegane H, Wada T, Yachie A, Ohara O, Morio T, Notarangelo LD, Imai K, Nonoyama S. RAG1 deficiency may present clinically as selective IgA deficiency. J Clin Immunol. 2015 Apr; 35(3):280-8. PMID: 25739914.
    Citations: 15     Fields:    Translation:Humans
  23. Crestani E, Lee J, Gorman M, Castells M, Dioun Broyles AF. IgE-mediated hypersensitivity reaction and desensitization to glatiramer acetate in a pediatric patient. Pediatr Allergy Immunol. 2014 Dec; 25(8):821-3. PMID: 25200765.
    Citations: 2     Fields:    Translation:Humans
  24. Crestani E, Choo S, Frugoni F, Lee YN, Richards S, Smart J, Notarangelo LD. RAG1 reversion mosaicism in a patient with Omenn syndrome. J Clin Immunol. 2014 Jul; 34(5):551-4. PMID: 24817258.
    Citations: 8     Fields:    Translation:HumansCells
  25. Crestani E, Lohman IC, Guerra S, Wright AL, Halonen M. Association of IL-5 cytokine production and in vivo IgE levels in infants and parents. J Allergy Clin Immunol. 2007 Oct; 120(4):820-6. PMID: 17628648.
    Citations: 8     Fields:    Translation:HumansCells
  26. Piacentini GL, Peroni D, Crestani E, Zardini F, Bodini A, Costella S, Boner AL. Exhaled air temperature in asthma: methods and relationship with markers of disease. Clin Exp Allergy. 2007 Mar; 37(3):415-9. PMID: 17359391.
    Citations: 18     Fields:    Translation:Humans
  27. Crestani E, Guerra S, Wright AL, Halonen M, Martinez FD. Parental asthma as a risk factor for the development of early skin test sensitization in children. J Allergy Clin Immunol. 2004 Feb; 113(2):284-90. PMID: 14767443.
    Citations: 5     Fields:    Translation:HumansCells
  28. Yuile PG, Wielinga W, Crestani EA. Fractionated total body irradiation in bone marrow transplantation--an emphasis on lung dosimetry. Australas Radiol. 1983 Jul; 27(2):186-94. PMID: 6357181.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.