Harvard Catalyst Profiles

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Neil Vasdev, Ph.D.


1998 - 2002
Presentation Awards at Radiology Research Day
1999 - 2000
Presentation Awards in Biological and Medicinal Chemistry
E.S. Garnett Bursary in Medical Imaging
DOW Canada Excellence in Teaching
2001 - 2003
NSERC Postgraduate Scholarship
2003 - 2005
NSERC Postdoctoral Fellowship
Moissan Fellowship (Division of Fluorine Chemistry, American Chemical Society)
John M. Cleghorn Newly Established Researcher Award (University of Toronto)
2006 - 2007
Radiant Young Investigator Award (Canadian Society of Nuclear Medicine)
First Place Young Investigator Award (Radiopharmaceutical Sciences, Society of Nuclear Medicine)
2009 - 2014
Early Researcher Award (Ontario Ministry of Research and Innovation)


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG052414 (VASDEV, NEIL) Aug 15, 2018 - May 31, 2022
    Translation of tau-selective PET radiopharmaceuticals in Alzheimers patients
    Role: Principal Investigator
  2. R01AG054473 (VASDEV, NEIL) Dec 15, 2016 - Nov 30, 2020
    Neuro-PET Radiotracer Discovery for Imaging Glycogen Synthase Kinase-3
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Murrell E, Pham JM, Sowa AR, Brooks AF, Kilbourn MR, Scott PJH, Vasdev N. Classics in Neuroimaging: Development of Positron Emission Tomography Tracers for Imaging the GABAergic Pathway. ACS Chem Neurosci. 2020 Jun 24. PMID: 32578977.
  2. Varlow C, Boileau I, Wey HY, Liang SH, Vasdev N. Classics in Neuroimaging: Imaging the Endocannabinoid Pathway with PET. ACS Chem Neurosci. 2020 Jul 01; 11(13):1855-1862. PMID: 32559067.
  3. Narayanaswami V, Tong J, Fiorino F, Severino B, Sparaco R, Magli E, Giordano F, Bloomfield PM, Prabhakaran J, Mann JJ, Vasdev N, Dahl K, Kumar JSD. Synthesis, in vitro and in vivo evaluation of 11C-O-methylated arylpiperazines as potential serotonin 1A (5-HT1A) receptor antagonist radiotracers. EJNMMI Radiopharm Chem. 2020 May 19; 5(1):13. PMID: 32430632.
  4. Duffy IR, Vasdev N, Dahl K. Copper(I)-Mediated 11C-Carboxylation of (Hetero)arylstannanes. ACS Omega. 2020 Apr 14; 5(14):8242-8250. PMID: 32309734.
  5. Attwells S, Setiawan E, Rusjan PM, Xu C, Hutton C, Rafiei D, Varughese B, Kahn A, Kish SJ, Vasdev N, Houle S, Meyer JH. Translocator Protein Distribution Volume Predicts Reduction of Symptoms During Open-Label Trial of Celecoxib in Major Depressive Disorder. Biol Psychiatry. 2020 Mar 29. PMID: 32402468.
  6. Varlow C, Murrell E, Holland JP, Kassenbrock A, Shannon W, Liang SH, Vasdev N, Stephenson NA. Revisiting the Radiosynthesis of [18F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer's Disease. Molecules. 2020 Feb 22; 25(4). PMID: 32098347.
  7. Attwells S, Setiawan E, Wilson AA, Rusjan PM, Miler L, Xu C, Hutton C, Husain MI, Kish S, Vasdev N, Houle S, Meyer JH. Replicating predictive serum correlates of greater translocator protein distribution volume in brain. Neuropsychopharmacology. 2020 May; 45(6):925-931. PMID: 31683271.
  8. Bernard-Gauthier V, Mossine AV, Knight A, Patnaik D, Zhao WN, Cheng C, Krishnan HS, Xuan LL, Chindavong PS, Reis SA, Chen JM, Shao X, Stauff J, Arteaga J, Sherman P, Salem N, Bonsall D, Amaral B, Varlow C, Wells L, Martarello L, Patel S, Liang SH, Kurumbail RG, Haggarty SJ, Scott PJH, Vasdev N. Structural Basis for Achieving GSK-3ß Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery. J Med Chem. 2019 11 14; 62(21):9600-9617. PMID: 31535859.
  9. Dahl K, Garcia A, Stephenson NA, Vasdev N. "In-loop" 18 F-fluorination: A proof-of-concept study. J Labelled Comp Radiopharm. 2019 06 15; 62(7):292-297. PMID: 31083778.
  10. Moriguchi S, Wilson AA, Miler L, Rusjan PM, Vasdev N, Kish SJ, Rajkowska G, Wang J, Bagby M, Mizrahi R, Varughese B, Houle S, Meyer JH. Monoamine Oxidase B Total Distribution Volume in the Prefrontal Cortex of Major Depressive Disorder: An [11C]SL25.1188 Positron Emission Tomography Study. JAMA Psychiatry. 2019 06 01; 76(6):634-641. PMID: 30840042.
  11. Osovizky A, Laster B, Wilson AA, Bloomfield P, Sarusi B, Vasdev N, Bell T, Garcia A, Houle S. New detection configuration for low activity levels of PET tracers during the analysis of plasma samples. Appl Radiat Isot. 2019 Sep; 151:317-330. PMID: 31376719.
  12. Dahl K, Bernard-Gauthier V, Nag S, Varnäs K, Narayanaswami V, Mahdi Moein M, Arakawa R, Vasdev N, Halldin C. Synthesis and preclinical evaluation of [18F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B. Bioorg Med Chem Lett. 2019 07 01; 29(13):1624-1627. PMID: 31060887.
  13. Liang SH, Wang L, Stephenson NA, Rotstein BH, Vasdev N. Facile 18F labeling of non-activated arenes via a spirocyclic iodonium(III) ylide method and its application in the synthesis of the mGluR5 PET radiopharmaceutical [18F]FPEB. Nat Protoc. 2019 05; 14(5):1530-1545. PMID: 30980032.
  14. Chen Z, Mori W, Deng X, Cheng R, Ogasawara D, Zhang G, Schafroth MA, Dahl K, Fu H, Hatori A, Shao T, Zhang Y, Yamasaki T, Zhang X, Rong J, Yu Q, Hu K, Fujinaga M, Xie L, Kumata K, Gou Y, Chen J, Gu S, Bao L, Wang L, Collier TL, Vasdev N, Shao Y, Ma JA, Cravatt BF, Fowler C, Josephson L, Zhang MR, Liang SH. Design, Synthesis, and Evaluation of Reversible and Irreversible Monoacylglycerol Lipase Positron Emission Tomography (PET) Tracers Using a "Tail Switching" Strategy on a Piperazinyl Azetidine Skeleton. J Med Chem. 2019 04 11; 62(7):3336-3353. PMID: 30829483.
  15. Narayanaswami V, Drake LR, Brooks AF, Meyer JH, Houle S, Kilbourn MR, Scott PJH, Vasdev N. Classics in Neuroimaging: Development of PET Tracers for Imaging Monoamine Oxidases. ACS Chem Neurosci. 2019 04 17; 10(4):1867-1871. PMID: 30789704.
  16. Deng X, Rong J, Wang L, Vasdev N, Zhang L, Josephson L, Liang SH. Chemistry for Positron Emission Tomography: Recent Advances in 11 C-, 18 F-, 13 N-, and 15 O-Labeling Reactions. Angew Chem Int Ed Engl. 2019 02 25; 58(9):2580-2605. PMID: 30054961.
    Citations:    Fields:    
  17. Duffy IR, Boyle AJ, Vasdev N. Improving PET Imaging Acquisition and Analysis With Machine Learning: A Narrative Review With Focus on Alzheimer's Disease and Oncology. Mol Imaging. 2019 Jan-Dec; 18:1536012119869070. PMID: 31429375.
  18. Varlow C, Szames D, Dahl K, Bernard-Gauthier V, Vasdev N. Fluorine-18: an untapped resource in inorganic chemistry. Chem Commun (Camb). 2018 Oct 18; 54(84):11835-11842. PMID: 30191929.
    Citations:    Fields:    
  19. Cheng R, Mori W, Ma L, Alhouayek M, Hatori A, Zhang Y, Ogasawara D, Yuan G, Chen Z, Zhang X, Shi H, Yamasaki T, Xie L, Kumata K, Fujinaga M, Nagai Y, Minamimoto T, Svensson M, Wang L, Du Y, Ondrechen MJ, Vasdev N, Cravatt BF, Fowler C, Zhang MR, Liang SH. In Vitro and in Vivo Evaluation of 11C-Labeled Azetidinecarboxylates for Imaging Monoacylglycerol Lipase by PET Imaging Studies. J Med Chem. 2018 03 22; 61(6):2278-2291. PMID: 29481079.
    Citations:    Fields:    
  20. Collier TL, Dahl K, Stephenson NA, Holland JP, Riley A, Liang SH, Vasdev N. Recent applications of a single quadrupole mass spectrometer in 11C, 18F and radiometal chemistry. J Fluor Chem. 2018 Jun; 210:46-55. PMID: 30410189.
  21. Krishnan HS, Bernard-Gauthier V, Placzek MS, Dahl K, Narayanaswami V, Livni E, Chen Z, Yang J, Collier TL, Ran C, Hooker JM, Liang SH, Vasdev N. Metal Protein-Attenuating Compound for PET Neuroimaging: Synthesis and Preclinical Evaluation of [11C]PBT2. Mol Pharm. 2018 02 05; 15(2):695-702. PMID: 29298483.
    Citations:    Fields:    
  22. Narayanaswami V, Dahl K, Bernard-Gauthier V, Josephson L, Cumming P, Vasdev N. Emerging PET Radiotracers and Targets for Imaging of Neuroinflammation in Neurodegenerative Diseases: Outlook Beyond TSPO. Mol Imaging. 2018 Jan-Dec; 17:1536012118792317. PMID: 30203712.
    Citations:    Fields:    
  23. Josephson L, Stratman N, Liu Y, Qian F, Liang SH, Vasdev N, Patel S. The Binding of BF-227-Like Benzoxazoles to Human a-Synuclein and Amyloid ß Peptide Fibrils. Mol Imaging. 2018 Jan-Dec; 17:1536012118796297. PMID: 30213230.
    Citations:    Fields:    
  24. Collier TL, Liang SH, Mann JJ, Vasdev N, Kumar JSD. Microfluidic radiosynthesis of [18F]FEMPT, a high affinity PET radiotracer for imaging serotonin receptors. Beilstein J Org Chem. 2017; 13:2922-2927. PMID: 29564020.
    Citations: 1     
  25. Bernard-Gauthier V, Lepage ML, Waengler B, Bailey JJ, Liang SH, Perrin DM, Vasdev N, Schirrmacher R. Recent Advances in 18F Radiochemistry: A Focus on B-18F, Si-18F, Al-18F, and C-18F Radiofluorination via Spirocyclic Iodonium Ylides. J Nucl Med. 2018 04; 59(4):568-572. PMID: 29284673.
    Citations:    Fields:    
  26. Cumming P, Burgher B, Patkar O, Breakspear M, Vasdev N, Thomas P, Liu GJ, Banati R. Sifting through the surfeit of neuroinflammation tracers. J Cereb Blood Flow Metab. 2018 02; 38(2):204-224. PMID: 29256293.
    Citations: 1     Fields:    
  27. Bernard-Gauthier V, Collier TL, Liang SH, Vasdev N. Discovery of PET radiopharmaceuticals at the academia-industry interface. Drug Discov Today Technol. 2017 Nov; 25:19-26. PMID: 29233263.
    Citations: 3     Fields:    Translation:HumansAnimals
  28. Yuan G, Jankins TC, Patrick CG, Philbrook P, Sears O, Hatfield S, Sitkovsky M, Vasdev N, Liang SH, Ondrechen MJ, Pollastri MP, Jones GB. Fluorinated Adenosine A2A Receptor Antagonists Inspired by Preladenant as Potential Cancer Immunotherapeutics. Int J Med Chem. 2017; 2017:4852537. PMID: 29201461.
  29. Makaretz SJ, Quimby M, Collins J, Makris N, McGinnis S, Schultz A, Vasdev N, Johnson KA, Dickerson BC. Flortaucipir tau PET imaging in semantic variant primary progressive aphasia. J Neurol Neurosurg Psychiatry. 2018 10; 89(10):1024-1031. PMID: 28986472.
    Citations: 7     Fields:    
  30. Krishnan HS, Ma L, Vasdev N, Liang SH. 18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography. Chemistry. 2017 Nov 07; 23(62):15553-15577. PMID: 28704575.
    Citations:    Fields:    Translation:Humans
  31. Dahl K, Collier TL, Cheng R, Zhang X, Sadovski O, Liang SH, Vasdev N. "In-loop" [11 C]CO2 fixation: Prototype and proof of concept. J Labelled Comp Radiopharm. 2018 03; 61(3):252-262. PMID: 28600835.
    Citations: 2     Fields:    
  32. Kanthan M, Cumming P, Hooker JM, Vasdev N. Classics in Neuroimaging: Imaging the Dopaminergic Pathway with PET. ACS Chem Neurosci. 2017 09 20; 8(9):1817-1819. PMID: 28719177.
    Citations:    Fields:    Translation:Humans
  33. Vasdev N, Alavi A. Novel PET Radiotracers with Potential Clinical Applications. PET Clin. 2017 07; 12(3):xi-xii. PMID: 28576174.
    Citations:    Fields:    
  34. Collier TL, Normandin MD, Stephenson NA, Livni E, Liang SH, Wooten DW, Esfahani SA, Stabin MG, Mahmood U, Chen J, Wang W, Maresca K, Waterhouse RN, El Fakhri G, Richardson P, Vasdev N. Synthesis and preliminary PET imaging of 11C and 18F isotopologues of the ROS1/ALK inhibitor lorlatinib. Nat Commun. 2017 06 08; 8:15761. PMID: 28594000.
    Citations: 4     Fields:    Translation:HumansAnimals
  35. Wang L, Cheng R, Fujinaga M, Yang J, Zhang Y, Hatori A, Kumata K, Yang J, Vasdev N, Du Y, Ran C, Zhang MR, Liang SH. A Facile Radiolabeling of [18F]FDPA via Spirocyclic Iodonium Ylides: Preliminary PET Imaging Studies in Preclinical Models of Neuroinflammation. J Med Chem. 2017 06 22; 60(12):5222-5227. PMID: 28530834.
    Citations: 2     Fields:    Translation:Animals
  36. Ma L, Placzek MS, Hooker JM, Vasdev N, Liang SH. [11C]Cyanation of arylboronic acids in aqueous solutions. Chem Commun (Camb). 2017 Jun 21; 53(49):6597-6600. PMID: 28580477.
    Citations: 2     Fields:    
  37. Xia C, Makaretz SJ, Caso C, McGinnis S, Gomperts SN, Sepulcre J, Gomez-Isla T, Hyman BT, Schultz A, Vasdev N, Johnson KA, Dickerson BC. Association of In Vivo [18F]AV-1451 Tau PET Imaging Results With Cortical Atrophy and Symptoms in Typical and Atypical Alzheimer Disease. JAMA Neurol. 2017 04 01; 74(4):427-436. PMID: 28241163.
    Citations: 27     Fields:    Translation:Humans
  38. Collier TL, Yokell DL, Livni E, Rice PA, Celen S, Serdons K, Neelamegam R, Bormans G, Harris D, Walji A, Hostetler ED, Bennacef I, Vasdev N. cGMP production of the radiopharmaceutical [18 F]MK-6240 for PET imaging of human neurofibrillary tangles. J Labelled Comp Radiopharm. 2017 05 15; 60(5):263-269. PMID: 28185305.
    Citations: 1     Fields:    Translation:HumansCells
  39. Hu K, Patnaik D, Collier TL, Lee KN, Gao H, Swoyer MR, Rotstein BH, Krishnan HS, Liang SH, Wang J, Yan Z, Hooker JM, Vasdev N, Haggarty SJ, Ngai MY. Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3ß Ligands for Positron Emission Tomography Imaging. ACS Med Chem Lett. 2017 Mar 09; 8(3):287-292. PMID: 28337318.
    Citations: 1     
  40. Khotavivattana T, Calderwood S, Verhoog S, Pfeifer L, Preshlock S, Vasdev N, Collier TL, Gouverneur V. Synthesis and Reactivity of 18F-Labeled a,a-Difluoro-a-(aryloxy)acetic Acids. Org Lett. 2017 02 03; 19(3):568-571. PMID: 28085289.
    Citations:    Fields:    
  41. Collier TL, Maresca KP, Normandin MD, Richardson P, McCarthy TJ, Liang SH, Waterhouse RN, Vasdev N. Brain Penetration of the ROS1/ALK Inhibitor Lorlatinib Confirmed by PET. Mol Imaging. 2017 Jan-Dec; 16:1536012117736669. PMID: 29067878.
    Citations:    Fields:    Translation:HumansAnimals
  42. Lin SF, Bois F, Holden D, Nabulsi N, Pracitto R, Gao H, Kapinos M, Teng JK, Shirali A, Ropchan J, Carson RE, Elmore CS, Vasdev N, Huang Y. The Search for a Subtype-Selective PET Imaging Agent for the GABAA Receptor Complex: Evaluation of the Radiotracer [11C]ADO in Nonhuman Primates. Mol Imaging. 2017 Jan-Dec; 16:1536012117731258. PMID: 28929924.
    Citations: 1     Fields:    Translation:Animals
  43. Yuan G, Wang F, Stephenson NA, Wang L, Rotstein BH, Vasdev N, Tang P, Liang SH. Metal-free 18F-labeling of aryl-CF2H via nucleophilic radiofluorination and oxidative C-H activation. Chem Commun (Camb). 2016 12 20; 53(1):126-129. PMID: 27917423.
    Citations:    Fields:    Translation:Cells
  44. Gomperts SN, Locascio JJ, Makaretz SJ, Schultz A, Caso C, Vasdev N, Sperling R, Growdon JH, Dickerson BC, Johnson K. Tau Positron Emission Tomographic Imaging in the Lewy Body Diseases. JAMA Neurol. 2016 Nov 01; 73(11):1334-1341. PMID: 27654968.
    Citations: 29     Fields:    Translation:Humans
  45. Ding Y, Gao H, Zhang Y, Li Y, Vasdev N, Gao Y, Chen Y, Zhang Q. Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells. J Hematol Oncol. 2016 Sep 22; 9(1):93. PMID: 27658462.
    Citations: 3     Fields:    
  46. Wooten DW, Guehl NJ, Verwer EE, Shoup TM, Yokell DL, Zubcevik N, Vasdev N, Zafonte RD, Johnson KA, El Fakhri G, Normandin MD. Pharmacokinetic Evaluation of the Tau PET Radiotracer 18F-T807 (18F-AV-1451) in Human Subjects. J Nucl Med. 2017 Mar; 58(3):484-491. PMID: 27660144.
    Citations: 13     Fields:    Translation:Humans
  47. Rotstein BH, Placzek MS, Krishnan HS, Pekošak A, Collier TL, Wang C, Liang SH, Burstein ES, Hooker JM, Vasdev N. Preclinical PET Neuroimaging of [11C]Bexarotene. Mol Imaging. 2016; 15. PMID: 27553293.
    Citations: 1     Fields:    Translation:Animals
  48. Rotstein BH, Liang SH, Placzek MS, Hooker JM, Gee AD, Dollé F, Wilson AA, Vasdev N. (11)C[double bond, length as m-dash]O bonds made easily for positron emission tomography radiopharmaceuticals. Chem Soc Rev. 2016 Aug 22; 45(17):4708-26. PMID: 27276357.
    Citations: 12     Fields:    Translation:HumansCells
  49. Vasdev N, Collier TL. Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis. Pharmaceuticals (Basel). 2016 Aug 17; 9(3). PMID: 27548189.
    Citations: 1     
  50. Yuan G, Jones GB, Vasdev N, Liang SH. Radiosynthesis and preliminary PET evaluation of (18)F-labeled 2-(1-(3-fluorophenyl)-2-oxo-5-(pyrimidin-2-yl)-1,2-dihydropyridin-3-yl)benzonitrile for imaging AMPA receptors. Bioorg Med Chem Lett. 2016 10 01; 26(19):4857-4860. PMID: 27546294.
    Citations: 1     Fields:    Translation:Animals
  51. Shi H, Braun A, Wang L, Liang SH, Vasdev N, Ritter T. Synthesis of (18) F-Difluoromethylarenes from Aryl (Pseudo) Halides. Angew Chem Int Ed Engl. 2016 08 26; 55(36):10786-90. PMID: 27491349.
    Citations: 1     Fields:    Translation:Cells
  52. Liang SH, Chen JM, Normandin MD, Chang JS, Chang GC, Taylor CK, Trapa P, Plummer MS, Para KS, Conn EL, Lopresti-Morrow L, Lanyon LF, Cook JM, Richter KE, Nolan CE, Schachter JB, Janat F, Che Y, Shanmugasundaram V, Lefker BA, Enerson BE, Livni E, Wang L, Guehl NJ, Patnaik D, Wagner FF, Perlis R, Holson EB, Haggarty SJ, El Fakhri G, Kurumbail RG, Vasdev N. Discovery of a Highly Selective Glycogen Synthase Kinase-3 Inhibitor (PF-04802367) That Modulates Tau Phosphorylation in the Brain: Translation for PET Neuroimaging. Angew Chem Int Ed Engl. 2016 08 08; 55(33):9601-5. PMID: 27355874.
    Citations: 5     Fields:    Translation:HumansCells
  53. Wang L, Mori W, Cheng R, Yui J, Hatori A, Ma L, Zhang Y, Rotstein BH, Fujinaga M, Shimoda Y, Yamasaki T, Xie L, Nagai Y, Minamimoto T, Higuchi M, Vasdev N, Zhang MR, Liang SH. Synthesis and Preclinical Evaluation of Sulfonamido-based [(11)C-Carbonyl]-Carbamates and Ureas for Imaging Monoacylglycerol Lipase. Theranostics. 2016; 6(8):1145-59. PMID: 27279908.
    Citations: 3     Fields:    Translation:Animals
  54. Rotstein BH, Wang L, Liu RY, Patteson J, Kwan EE, Vasdev N, Liang SH. Mechanistic Studies and Radiofluorination of Structurally Diverse Pharmaceuticals with Spirocyclic Iodonium(III) Ylides. Chem Sci. 2016 Jul 01; 7(7):4407-4417. PMID: 27540460.
    Citations: 7     
  55. Kassenbrock A, Vasdev N, Liang SH. Selected PET Radioligands for Ion Channel Linked Neuroreceptor Imaging: Focus on GABA, NMDA and nACh Receptors. Curr Top Med Chem. 2016; 16(16):1830-42. PMID: 26975506.
    Citations: 2     Fields:    Translation:HumansCells
  56. Johnson KA, Schultz A, Betensky RA, Becker JA, Sepulcre J, Rentz D, Mormino E, Chhatwal J, Amariglio R, Papp K, Marshall G, Albers M, Mauro S, Pepin L, Alverio J, Judge K, Philiossaint M, Shoup T, Yokell D, Dickerson B, Gomez-Isla T, Hyman B, Vasdev N, Sperling R. Tau positron emission tomographic imaging in aging and early Alzheimer disease. Ann Neurol. 2016 Jan; 79(1):110-9. PMID: 26505746.
    Citations: 116     Fields:    Translation:Humans
  57. Rashidian M, Wang L, Edens JG, Jacobsen JT, Hossain I, Wang Q, Victora GD, Vasdev N, Ploegh H, Liang SH. Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics. Angew Chem Int Ed Engl. 2016 Jan 11; 55(2):528-533. PMID: 26630549.
    Citations: 5     Fields:    Translation:AnimalsCells
  58. Wang L, Yui J, Wang Q, Zhang Y, Mori W, Shimoda Y, Fujinaga M, Kumata K, Yamasaki T, Hatori A, Rotstein BH, Collier TL, Ran C, Vasdev N, Zhang MR, Liang SH. Synthesis and Preliminary PET Imaging Studies of a FAAH Radiotracer ([¹¹C]MPPO) Based on a-Ketoheterocyclic Scaffold. ACS Chem Neurosci. 2016 Jan 20; 7(1):109-18. PMID: 26505525.
    Citations: 3     Fields:    Translation:Animals
  59. Marquié M, Normandin MD, Vanderburg CR, Costantino IM, Bien EA, Rycyna LG, Klunk WE, Mathis CA, Ikonomovic MD, Debnath ML, Vasdev N, Dickerson BC, Gomperts SN, Growdon JH, Johnson KA, Frosch MP, Hyman BT, Gómez-Isla T. Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Ann Neurol. 2015 Nov; 78(5):787-800. PMID: 26344059.
    Citations: 114     Fields:    Translation:HumansCells
  60. Liang SH, Vasdev N. Total Radiosynthesis: Thinking outside "the box". Aust J Chem. 2015 Sep; 68(9):1319-1328. PMID: 27512156.
    Citations: 3     
  61. Jacobson O, Weiss ID, Wang L, Wang Z, Yang X, Dewhurst A, Ma Y, Zhu G, Niu G, Kiesewetter DO, Vasdev N, Liang SH, Chen X. 18F-Labeled Single-Stranded DNA Aptamer for PET Imaging of Protein Tyrosine Kinase-7 Expression. J Nucl Med. 2015 Nov; 56(11):1780-1785. PMID: 26315836.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  62. Wang L, Jacobson O, Avdic D, Rotstein BH, Weiss ID, Collier L, Chen X, Vasdev N, Liang SH. Ortho-Stabilized (18) F-Azido Click Agents and their Application in PET Imaging with Single-Stranded DNA Aptamers. Angew Chem Int Ed Engl. 2015 Oct 19; 54(43):12777-81. PMID: 26308650.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  63. Calderwood S, Collier TL, Gouverneur V, Liang SH, Vasdev N. Synthesis of 18F-Arenes from Spirocyclic Iodonium(III) Ylides via Continuous-Flow Microfluidics. J Fluor Chem. 2015 Oct; 178:249-253. PMID: 27512233.
    Citations: 1     
  64. Liang SH, Southon AG, Fraser BH, Krause-Heuer AM, Zhang B, Shoup TM, Lewis R, Volitakis I, Han Y, Greguric I, Bush AI, Vasdev N. Novel Fluorinated 8-Hydroxyquinoline Based Metal Ionophores for Exploring the Metal Hypothesis of Alzheimer's Disease. ACS Med Chem Lett. 2015 Sep 10; 6(9):1025-9. PMID: 26396692.
    Citations: 3     
  65. Rotstein BH, Liang SH, Belov VV, Livni E, Levine DB, Bonab AA, Papisov MI, Perlis RH, Vasdev N. Practical Radiosynthesis and Preclinical Neuroimaging of [11C]isradipine, a Calcium Channel Antagonist. Molecules. 2015 May 26; 20(6):9550-9. PMID: 26016546.
    Citations:    Fields:    Translation:Animals
  66. Shoup TM, Bonab AA, Wilson AA, Vasdev N. Synthesis and preclinical evaluation of [¹8F]FCHC for neuroimaging of fatty acid amide hydrolase. Mol Imaging Biol. 2015 Apr; 17(2):257-63. PMID: 25273322.
    Citations: 2     Fields:    Translation:Animals
  67. Liang SH, Holland JP, Stephenson NA, Kassenbrock A, Rotstein BH, Daignault CP, Lewis R, Collier L, Hooker JM, Vasdev N. PET neuroimaging studies of [(18)F]CABS13 in a double transgenic mouse model of Alzheimer's disease and nonhuman primates. ACS Chem Neurosci. 2015 Apr 15; 6(4):535-41. PMID: 25776827.
    Citations: 3     Fields:    Translation:HumansAnimals
  68. Stephenson NA, Holland JP, Kassenbrock A, Yokell DL, Livni E, Liang SH, Vasdev N. Iodonium ylide-mediated radiofluorination of 18F-FPEB and validation for human use. J Nucl Med. 2015 Mar; 56(3):489-92. PMID: 25655630.
    Citations: 12     Fields:    Translation:HumansCells
  69. Heidari P, Deng F, Esfahani SA, Leece AK, Shoup TM, Vasdev N, Mahmood U. Pharmacodynamic imaging guides dosing of a selective estrogen receptor degrader. Clin Cancer Res. 2015 Mar 15; 21(6):1340-7. PMID: 25609068.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  70. Liang SH, Yokell DL, Jackson RN, Rice PA, Livni E, Alagille D, Tamagnan G, Collier TL, Vasdev N. Synthesis of 3-[18F]Fluoro-5-(2-pyridinylethynyl)benzonitrile ([18F]FPEB). Radiochemical Synthesis: Radiopharmaceuticals for Positron Emission Tomography” . 2015; 2.
  71. Boros E, Bowen AM, Josephson L, Vasdev N, Holland JP. Chelate-free metal ion binding and heat-induced radiolabeling of iron oxide nanoparticles. Chem Sci. 2015; 6:225-236.
  72. Hill DE, Vasdev N, Holland JP. Evaluating the accuracy of density functional theory for calculating 1H and 13C NMR chemical shifts in drug molecules. Comput Theor Chem. 2015; 1051:161-172.
  73. Hicks JW, Sadovski O, Parkes J, Houle S, Hay BA, Carter RL, Wilson AA, Vasdev N. Radiosynthesis and ex vivo evaluation of [(18)F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET. Bioorg Med Chem Lett. 2015 Jan 15; 25(2):288-91. PMID: 25488845.
    Citations: 2     Fields:    Translation:AnimalsCells
  74. Liang SH, Yokell DL, Normandin MD, Rice PA, Jackson RN, Shoup TM, Brady TJ, Fakhri GE, Collier TL, Vasdev N. First Human Use of a Radiopharmaceutical Prepared by Continuous-Flow Microfluidic Radiofluorination: Proof of Concept with the Tau Imaging Agent [18F]T807. Mol Imaging. 2014 Oct 01; 13(8):7290201400025. PMID: 28650281.
  75. Boros E, Bowen AM, Josephson L, Vasdev N, Holland JP. Chelate-free metal ion binding and heat-induced radiolabeling of iron oxide nanoparticles. Chem Sci. 2015 Jan 01; 6(1):225-236. PMID: 28553472.
    Citations: 10     
  76. Liang SH, Vasdev N. C(sp³)-¹8F bond formation by transition-metal-based [¹8F]fluorination. Angew Chem Int Ed Engl. 2014 Oct 20; 53(43):11416-8. PMID: 25243361.
    Citations: 5     Fields:    
  77. Rotstein BH, Wey HY, Shoup TM, Wilson AA, Liang SH, Hooker JM, Vasdev N. PET imaging of fatty acid amide hydrolase with [(18)F]DOPP in nonhuman primates. Mol Pharm. 2014 Nov 03; 11(11):3832-8. PMID: 25004399.
    Citations: 3     Fields:    Translation:Animals
  78. Rotstein BH, Stephenson NA, Vasdev N, Liang SH. Spirocyclic hypervalent iodine(III)-mediated radiofluorination of non-activated and hindered aromatics. Nat Commun. 2014 Jul 09; 5:4365. PMID: 25007318.
    Citations: 27     Fields:    Translation:Cells
  79. Hicks JW, Parkes J, Tong J, Houle S, Vasdev N, Wilson AA. Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors. Nucl Med Biol. 2014 Sep; 41(8):688-94. PMID: 24969632.
    Citations: 6     Fields:    Translation:Animals
  80. Holland JP, Vasdev N. Charting the mechanism and reactivity of zirconium oxalate with hydroxamate ligands using density functional theory: implications in new chelate design. Dalton Trans. 2014 Jul 14; 43(26):9872-84. PMID: 24722728.
    Citations: 9     Fields:    
  81. Liang SH, Yokell DL, Jackson RN, Rice PA, Callahan R, Johnson KA, Alagille D, Tamagnan G, Collier TL, Vasdev N. Microfluidic continuous-flow radiosynthesis of [18F]FPEB suitable for human PET imaging. Medchemcomm. 2014 Apr 01; 5(4):432-435. PMID: 25431646.
    Citations: 5     
  82. Rotstein BH, Hooker JM, Woo J, Collier TL, Brady TJ, Liang SH, Vasdev N. Synthesis of [(11)C]Bexarotene by Cu-Mediated [(11)C]Carbon Dioxide Fixation and Preliminary PET Imaging. ACS Med Chem Lett. 2014 Jun 12; 5(6):668-72. PMID: 24944741.
    Citations: 9     
  83. Rusjan PM, Wilson AA, Miler L, Fan I, Mizrahi R, Houle S, Vasdev N, Meyer JH. Kinetic modeling of the monoamine oxidase B radioligand [¹¹C]SL25.1188 in human brain with high-resolution positron emission tomography. J Cereb Blood Flow Metab. 2014 May; 34(5):883-9. PMID: 24517979.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  84. Liang SH, Yokell DL, Normandin MD, Rice PA, Jackson RN, Shoup TM, Brady TJ, El Fakhri G, Collier TL, Vasdev N. First human use of a radiopharmaceutical prepared by continuous-flow microfluidic radiofluorination: proof of concept with the tau imaging agent [18F]T807. Mol Imaging. 2014; 13. PMID: 25248283.
    Citations: 2     Fields:    Translation:Humans
  85. Shoup TM, McCauley JP, Lee Jr. DF, Chen R, Normandin MD,Bonab AA,El Fakhri G, Vasdev N. . Synthesis of the dopamine D2/D3 receptor agonist (+)-PHNO via supercritical fluid chromatography: Preliminary PET imaging study with [3-11C]-(+)-PHNO. Tetrahedron Lett. 2014; 55:682-685.
  86. Rotstein BH, Liang SH, Vasdev N. Clinical PET Research Realized by [11C]CO2-Fixation. Molecular Imaging Gateway. 2014; 8(2).
  87. Holland JP, Liang SH, Rotstein BH, Collier TL, Stephenson NA, Greguric I, Vasdev N. Alternative approaches for PET radiotracer development in Alzheimer's disease: imaging beyond plaque. J Labelled Comp Radiopharm. 2014 Apr; 57(4):323-31. PMID: 24327420.
    Citations: 11     Fields:    Translation:HumansAnimals
  88. Liang SH, Collier TL, Rotstein BH, Lewis R, Steck M, Vasdev N. Rapid microfluidic flow hydrogenation for reduction or deprotection of 18F-labeled compounds. Chem Commun (Camb). 2013 Oct 09; 49(78):8755-7. PMID: 23948863.
    Citations: 9     Fields:    Translation:Cells
  89. Shoup TM, Yokell DL, Rice PA, Jackson RN, Livni E, Johnson KA, Brady TJ, Vasdev N. A concise radiosynthesis of the tau radiopharmaceutical, [(18) F]T807. J Labelled Comp Radiopharm. 2013 Dec; 56(14):736-40. PMID: 24339014.
    Citations: 20     Fields:    
  90. Hicks JW, Parkes J, Sadovski O, Tong J, Houle S, Vasdev N, Wilson AA. Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase. Nucl Med Biol. 2013 Aug; 40(6):740-6. PMID: 23731552.
    Citations: 11     Fields:    Translation:Animals
  91. Rotstein BH, Liang SH, Holland JP, Collier TL, Hooker JM, Wilson AA, Vasdev N. 11CO2 fixation: a renaissance in PET radiochemistry. Chem Commun (Camb). 2013 Jun 25; 49(50):5621-9. PMID: 23673726.
    Citations: 19     Fields:    
  92. Sadovski O, Hicks JW, Parkes J, Raymond R, Nobrega J, Houle S, Cipriano M, Fowler CJ, Vasdev N, Wilson AA. Development and characterization of a promising fluorine-18 labelled radiopharmaceutical for in vivo imaging of fatty acid amide hydrolase. Bioorg Med Chem. 2013 Jul 15; 21(14):4351-7. PMID: 23712084.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  93. Holland JP, Cumming P, Vasdev N. PET radiopharmaceuticals for probing enzymes in the brain. Am J Nucl Med Mol Imaging. 2013; 3(3):194-216. PMID: 23638333.
    Citations: 10     
  94. Vasdev N, Green DE, Vines DC, McLarty K, McCormick PN, Moran MD, Houle S, Wilson AA, Reilly RM. Positron-emission tomography imaging of the TSPO with [(18)F]FEPPA in a preclinical breast cancer model. Cancer Biother Radiopharm. 2013 Apr; 28(3):254-9. PMID: 23350894.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  95. Wilson AA, Hicks JW, Sadovski O, Parkes J, Tong J, Houle S, Fowler CJ, Vasdev N. Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography. J Med Chem. 2013 Jan 10; 56(1):201-9. PMID: 23214511.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  96. Carroll L, Perumal M, Vasdev N, Robins E, Aboagye EO. Radiosynthesis and in vivo tumor uptake of 2-deoxy-2-[(18)F]fluoro-myo-inositol. Bioorg Med Chem Lett. 2012 Oct 01; 22(19):6148-50. PMID: 22944120.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  97. Holland JP, Cumming P, Vasdev N. PET of signal transduction pathways in cancer. J Nucl Med. 2012 Sep; 53(9):1333-6. PMID: 22879078.
    Citations: 7     Fields:    Translation:HumansCells
  98. Moran MD, Wilson AA, Elmore CS, Parkes J, Ng A, Sadovski O, Graff A, Daskalakis ZJ, Houle S, Chapdelaine MJ, Vasdev N. Development of new carbon-11 labelled radiotracers for imaging GABAA- and GABAB-benzodiazepine receptors. Bioorg Med Chem. 2012 Jul 15; 20(14):4482-8. PMID: 22717238.
    Citations: 3     Fields:    Translation:Animals
  99. Hicks JW, Wilson AA, Rubie EA, Woodgett JR, Houle S, Vasdev N. Towards the preparation of radiolabeled 1-aryl-3-benzyl ureas: Radiosynthesis of [(11)C-carbonyl] AR-A014418 by [(11)C]CO(2) fixation. Bioorg Med Chem Lett. 2012 Mar 01; 22(5):2099-101. PMID: 22321216.
    Citations: 15     Fields:    Translation:Humans
  100. Vasdev N, Cao P, van Oosten EM, Wilson AA, Houle S, Hao G, Sun X, Slavine N, Alhasan M, Antich PP, Bonte FJ, Kulkarni P. . Synthesis and PET imaging studies of [18F]2-fluoroquinolin-8-ol ([18F]CABS13) in transgenic mouse models of Alzheimer’s disease. Med Chem Commun. 2012; 3(10):1228-1230.
  101. Cumming P, Vasdev N. The Assay of Enzyme Activity by Positron Emission Tomography. Neuromethods: Molecular Imaging in Clinical Neurosciences. 2012; 71:111-135.
  102. Cumming P, Vasdev N. Molecular imaging studies of second messenger pathways: Looking deeper than the membrane . Neuromethods: Molecular Imaging in Clinical Neurosciences. 2012; 71:137-148.
  103. Hicks JW, Lough AJ, Wilson AA, Vasdev N. (E)-2-(2-Methyl-cyclo-hexyl-idene)hydrazinecarbothio-amide. Acta Crystallogr Sect E Struct Rep Online. 2011 Nov; 67(Pt 11):o3005. PMID: 22220022.
  104. Stephenson KA, Wilson AA, Houle S, Vasdev N. Synthesis and in vitro evaluation of derivatives of the ß1-adrenergic receptor antagonist HX-CH 44. Bioorg Med Chem Lett. 2011 Sep 15; 21(18):5506-9. PMID: 21783363.
    Citations: 2     Fields:    Translation:HumansCells
  105. Vasdev N, Sadovski O, Moran MD, Parkes J, Meyer JH, Houle S, Wilson AA. Development of new radiopharmaceuticals for imaging monoamine oxidase B. Nucl Med Biol. 2011 Oct; 38(7):933-43. PMID: 21982565.
    Citations: 3     Fields:    Translation:Animals
  106. McLarty K, Moran MD, Scollard DA, Chan C, Sabha N, Mukherjee J, Guha A, McLaurin J, Nitz M, Houle S, Wilson AA, Reilly RM, Vasdev N. Comparisons of [18F]-1-deoxy-1-fluoro-scyllo-inositol with [18F]-FDG for PET imaging of inflammation, breast and brain cancer xenografts in athymic mice. Nucl Med Biol. 2011 Oct; 38(7):953-9. PMID: 21982567.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  107. Louie AS, Vasdev N, Valliant JF. Preparation, characterization, and screening of a high affinity organometallic probe for a-adrenergic receptors. J Med Chem. 2011 May 12; 54(9):3360-7. PMID: 21428421.
    Citations: 1     Fields:    Translation:HumansAnimals
  108. Vasdev N, Dorff PN, O'Neil JP, Chin FT, Hanrahan S, VanBrocklin HF. Metabolic stability of 6,7-dialkoxy-4-(2-, 3- and 4-[18F]fluoroanilino)quinazolines, potential EGFR imaging probes. Bioorg Med Chem. 2011 May 01; 19(9):2959-65. PMID: 21478021.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  109. Wilson AA, Garcia A, Parkes J, Houle S, Tong J, Vasdev N. [11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography. Nucl Med Biol. 2011 Feb; 38(2):247-53. PMID: 21315280.
    Citations: 19     Fields:    Translation:Animals
  110. Moran MD, Wilson AA, Stableford WT,Wong M, Garcia A, Houle, S, Vasdev N. A rapid one-step radiosynthesis of [11C]-d-threo-methylphenidate. J Labelled Compd Radiopharm. 2011; 54:168-170.
  111. Moran MD, Jones J-P, Wilson AA, Houle S, Prakash GKS, Olah GA, Vasdev N. Recharging” Group Electronegativities: A Simple Computational Method for Experimental Chemists and Chemical Educators. The Chemical Educator. 2011; 16:164-167.
  112. Vasdev N, Sadovski O, Garcia A, Dollé F, Meyer JH, Houle S, Wilson AA. Radiosynthesis of [11C]SL25.1188, via [11C]CO2 fixation, for Imaging Monoamine Oxidase B. J Labelled Compd Radiopharm. 2011; 54:678-680.
  113. van Oosten EM, Gerken M, Hazendonk P, Shank R, Houle S, Wilson AA, Vasdev N. Regioselective ring opening of 2-methylaziridine derivatives with 18F- and 19F-fluoride. Tetrahedron Lett. 2011; 52(32):4114-4116.
  114. Hicks JW, VanBrocklin HF, Wilson AA, Houle S, Vasdev N. Radiolabeled small molecule protein kinase inhibitors for imaging with PET or SPECT. Molecules. 2010 Nov 15; 15(11):8260-78. PMID: 21079565.
    Citations: 13     Fields:    Translation:HumansAnimals
  115. Wilson AA, Garcia A, Houle S, Sadovski O, Vasdev N. Synthesis and application of isocyanates radiolabeled with carbon-11. Chemistry. 2011 Jan 03; 17(1):259-64. PMID: 21207622.
    Citations: 14     Fields:    Translation:Cells
  116. Vasdev N, Moran MD, Tuononen HM, Chirakal R, Suontamo RJ, Bain AD, Schrobilgen GJ. NMR spectroscopic evidence for the intermediacy of XeF(3)(-) in XeF(2)/F(-) exchange, attempted syntheses and thermochemistry of XeF(3)(-) salts, and theoretical studies of the XeF(3)(-) anion. Inorg Chem. 2010 Oct 04; 49(19):8997-9004. PMID: 20799721.
    Citations:    Fields:    
  117. Lough AJ, Hicks JW, Valliant JF, Wilson AA, Vasdev N. N-(4-Meth-oxy-phen-yl)-N'-(5-nitro-1,3-thia-zol-2-yl)urea. Acta Crystallogr Sect E Struct Rep Online. 2010 Aug 18; 66(Pt 9):o2339. PMID: 21588684.
  118. Gerretsen P, Graff-Guerrero A, Menon M, Pollock BG, Kapur S, Vasdev N, Houle S, Mamo D. Is desire for social relationships mediated by the serotonergic system in the prefrontal cortex? An [(18)F]setoperone PET study. Soc Neurosci. 2010; 5(4):375-83. PMID: 20198536.
    Citations: 9     Fields:    Translation:Humans
  119. van Oosten EM, Wilson AA, Mamo DC, Pollock BG, Mulsant BH, Houle S, Vasdev N. Towards the Development of New Subtype-Specific Muscarinic Receptor Radiopharmaceuticals: Radiosynthesis and Ex Vivo Biodistribution of [18F]3-(4-(2-(2-(2-fluoroethoxy)ethoxy)ethylthio)-1,2,5-thiadiazol-3-yl)-1-methyl-1,2,5,6-tetrahydropyridine. Can J Chem. 2010; 88:1222-1232.
  120. Wilson AA, Garcia A, Houle S, Vasdev N. Direct fixation of [(11)C]-CO(2) by amines: formation of [(11)C-carbonyl]-methylcarbamates. Org Biomol Chem. 2010 Jan 21; 8(2):428-32. PMID: 20066280.
    Citations: 16     Fields:    Translation:Cells
  121. Vasdev N, Chio J, van Oosten EM, Nitz M, McLaurin J, Vines DC, Houle S, Reilly RM, Wilson AA. Synthesis and preliminary biological evaluations of [18F]-1-deoxy-1-fluoro-scyllo-inositol. Chem Commun (Camb). 2009 Oct 07; (37):5527-9. PMID: 19753345.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  122. Vasdev N, van Oosten EM, Stephenson KA, Zadikian N, Yudin AK, Lough AJ, Houle S, Wilson AA. [18F]Fluoroamines via ring-opening of N-Cbz-2-methylaziridine with [18F]-fluoride. Tetrahedron Lett. 2009; 50:544-547.
  123. Wilson AA, Garcia A, Houle S, Vasdev N. Utility of Commercial Radiosynthetic Modules in Captive Solvent [11C]-Methylation Reactions. J Labelled Compd Radiopharm. 2009; 52:490-492.
  124. van Oosten EM, Wilson AA, Stephenson KA, Mamo DC, Pollock BG, Mulsant BH, Yudin AK, Houle S, Vasdev N. An improved radiosynthesis of the muscarinic M2 radiopharmaceutical, [18F]FP-TZTP. Appl Radiat Isot. 2009 Apr; 67(4):611-6. PMID: 19186063.
    Citations: 1     Fields:    
  125. Stephenson KA, Wilson AA, Meyer JH, Houle S, Vasdev N. Facile radiosynthesis of fluorine-18 labeled beta-blockers. Synthesis, radiolabeling, and ex vivo biodistribution of [18F]-(2S and 2R)-1-(1-fluoropropan-2-ylamino)-3-(m-tolyloxy)propan-2-ol. J Med Chem. 2008 Aug 28; 51(16):5093-100. PMID: 18656910.
    Citations:    Fields:    Translation:Animals
  126. Stephenson KA, van Oosten EM, Wilson AA, Meyer JH, Houle S, Vasdev N. Synthesis and preliminary evaluation of [(18)F]-fluoro-(2S)-Exaprolol for imaging cerebral beta-adrenergic receptors with PET. Neurochem Int. 2008 Nov; 53(5):173-9. PMID: 18675864.
    Citations: 1     Fields:    Translation:Animals
  127. Vasdev N, Kulkarni PV, Wilson AA, Houle S, Lough AJ. 4-Bromo-8-methoxy-quinoline. Acta Crystallogr Sect E Struct Rep Online. 2008 May 21; 64(Pt 6):o1117. PMID: 21202628.
  128. van Oosten EM, Lough AJ, Vasdev N. N-Isopropyl-benzamide. Acta Crystallogr Sect E Struct Rep Online. 2008 May 07; 64(Pt 6):o1005. PMID: 21202531.
    Citations: 1     
  129. Wilson AA, Garcia A, Parkes J, McCormick P, Stephenson KA, Houle S, Vasdev N. Radiosynthesis and initial evaluation of [18F]-FEPPA for PET imaging of peripheral benzodiazepine receptors. Nucl Med Biol. 2008 Apr; 35(3):305-14. PMID: 18355686.
    Citations: 40     Fields:    Translation:AnimalsCells
  130. Vasdev N, LaRonde FJ, Woodgett JR, Garcia A, Rubie EA, Meyer JH, Houle S, Wilson AA. Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide. Bioorg Med Chem. 2008 May 01; 16(9):5277-84. PMID: 18346896.
    Citations: 1     Fields:    Translation:AnimalsCells
  131. Vasdev N, Seeman P, Garcia A, Stableford WT, Nobrega JN, Houle S, Wilson AA. Syntheses and in vitro evaluation of fluorinated naphthoxazines as dopamine D2/D3 receptor agonists: radiosynthesis, ex vivo biodistribution and autoradiography of [(18)F]F-PHNO. Nucl Med Biol. 2007 Feb; 34(2):195-203. PMID: 17307127.
    Citations: 7     Fields:    Translation:Animals
  132. Vasdev N, Wilson AA, Houle S, Lough AJ. N-(4-Methoxybenzyl)-N’-(5-nitro-1,3-thiazol-2-yl)urea. Acta Crystallogr Sect E. 2007; E63:o1653-o1655.
  133. Vasdev N, Natesan S, Galineau L, Garcia A, Stableford WT, McCormick P, Seeman P, Houle S, Wilson AA. Radiosynthesis, ex vivo and in vivo evaluation of [11C]preclamol as a partial dopamine D2 agonist radioligand for positron emission tomography. Synapse. 2006 Sep 15; 60(4):314-8. PMID: 16786538.
    Citations:    Fields:    Translation:Animals
  134. Vasdev N, Garcia A, Stableford WT, Young AB, Meyer JH, Houle S, Wilson AA. Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): a radiolabelled glycogen synthase kinase-3beta specific inhibitor for PET studies. Bioorg Med Chem Lett. 2005 Dec 01; 15(23):5270-3. PMID: 16202587.
    Citations: 18     Fields:    Translation:Animals
  135. Vasdev N, Dorff PN, Gibbs AR, Nandanan E, Reid L,O’Neil JP, VanBrocklin HF. Synthesis of 6-acrylamido-4-(2-[18F]fluoroanilino)quinazoline: An 18F irreversible inhibitor of the EGFR tyrosine kinase. J. Labelled Compd Radiopharm. 2005; 48:109-115.
  136. Vasdev N, Chirakal R, Ashique R, Schrobilgen GJ, Gulenchyn K . Syntheses of [18F]5-fluoro-3-nitro-L-tyrosine. Journal of Fluorine Chemistry. 2003; 121:9-14.
  137. Vasdev N, Pointner BE, Chirakal R, Schrobilgen GJ. On the preparation of fluorine-18 labelled XeF(2) and chemical exchange between fluoride ion and XeF(2). J Am Chem Soc. 2002 Oct 30; 124(43):12863-8. PMID: 12392433.
    Citations: 1     Fields:    
  138. Chirakal R, Vasdev N, Asselin M-C, Schrobilgen GJ, Nahmias C. The effect of aromatic fluorine substitution in L-DOPA on the in vivo behaviour of [18F]2-, [18F]5- and [18F]6-fluoro-L-DOPA in the human brain . Journal of Fluorine Chemistry. 2002; 115:33-39.
  139. Vasdev N, Chirakal R, Schrobilgen GJ, Nahmias C. Selectivity of elemental fluorine towards L-tyrosine and L-alpha-methyltyrosine in acidic media and the syntheses of their [18F]3-fluoro and [18F]3,5-difluoro derivatives. Journal of Fluorine Chemistry. 2001; 111:17-25.
  140. Chirakal R, Vasdev N, Schrobilgen GJ, Nahmias C. Radiochemical and NMR spectroscopic investigation of the solvent effect on the electrophilic elemental fluorination of L-DOPA: Synthesis of [18F]5-Fluoro-L-DOPA. Journal of Fluorine Chemistry. 1999; 1:87-94.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.