Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

rani sarkis, M.D.

Title
Institution
Department
Address
Profile Picture

Biography
2006
Alpha Omega Alpha
2009
Resident Research Award
2011
Resident Research Award
2015
Young Investigator Award
2019 - 2020
Junior Investigator Award

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K23NS119798 (SARKIS, RANI) Sep 1, 2021 - Jun 30, 2026
    NIH
    The contribution of late onset unexplained epilepsy to cognitive decline and its interaction with vascular and Alzheimer's disease pathologies
    Role: Principal Investigator
  2. (Rani Sarkis) Jul 1, 2019 - Dec 30, 2021
    American Epilepsy Society
    The Cognitive and Imaging Characteristics of Late Onset Idiopathic Epilepsy
    Role Description: This study will enroll patients with unexplained, late-onset seizures and compare their brain imaging, genetic tests, brain-wave testing and cognitive performance to healthy controls of the same age from the Harvard Aging Brain Study to identify causes and consequences of seizures in the elderly.
    Role: PI

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Azami H, Moguilner S, Penagos H, Sarkis RA, Arnold SE, Gomperts SN, Lam AD. EEG Entropy in REM Sleep as a Physiologic Biomarker in Early Clinical Stages of Alzheimer's Disease. J Alzheimers Dis. 2023 Jan 12. PMID: 36641682.
    Citations:    Fields:    
  2. Jing J, Ge W, Struck AF, Fernandes MB, Hong S, An S, Fatima S, Herlopian A, Karakis I, Halford JJ, Ng MC, Johnson EL, Appavu BL, Sarkis RA, Osman G, Kaplan PW, Dhakar MB, Jayagopal LA, Sheikh Z, Taraschenko O, Schmitt S, Haider HA, Kim JA, Swisher CB, Gaspard N, Cervenka MC, Rodriguez Ruiz AA, Lee JW, Tabaeizadeh M, Gilmore EJ, Nordstrom K, Yoo JY, Holmes MG, Herman ST, Williams JA, Pathmanathan J, Nascimento FA, Fan Z, Nasiri S, Shafi MM, Cash SS, Hoch DB, Cole AJ, Rosenthal ES, Zafar SF, Sun J, Westover MB. Interrater Reliability of Expert Electroencephalographers Identifying Seizures and Rhythmic and Periodic Patterns in Electroencephalograms. Neurology. 2022 Dec 02. PMID: 36460472.
    Citations:    Fields:    
  3. Lemus HN, Sarkis RA. Epilepsy care in nursing facilities: Knowledge gaps and opportunities. Epilepsy Behav. 2023 Jan; 138:108997. PMID: 36442262.
    Citations:    Fields:    Translation:Humans
  4. Sarkis RA. fMRI to Predict Naming Decline: Can We Improve the Grade From a C to an A? Epilepsy Curr. 2022 Nov-Dec; 22(6):345-347. PMID: 36426181; PMCID: PMC9661605.
    Citations:    
  5. Villamar MF, Sarkis RA, Pennell P, Kohane I, Beaulieu-Jones BK. Severity of Epilepsy and Response to Antiseizure Medications in Individuals With Multiple Sclerosis: Analysis of a Real-World Dataset. Neurol Clin Pract. 2022 Aug; 12(4):e49-e57. PMID: 36382117; PMCID: PMC9647818.
    Citations:    
  6. Sarkis RA. Levetiracetam in Alzheimer's Disease: Do Epileptologists Already Have the Cure? Epilepsy Curr. 2022 Jul-Aug; 22(4):225-227. PMID: 36187150; PMCID: PMC9483755.
    Citations:    
  7. Sarkis RA, Lucey BP. Moving towards core sleep outcomes in neurodegenerative disease-the time is now. Sleep. 2022 07 11; 45(7). PMID: 35552756.
    Citations:    Fields:    Translation:Humans
  8. Sarkis R. Memories in Persons with Epilepsy: They Are More Fragile Than You Think. Epilepsy Curr. 2022 Sep-Oct; 22(5):282-284. PMID: 36285204.
    Citations:    
  9. Abou Jaoude M, Jacobs CS, Sarkis RA, Jing J, Pellerin KR, Cole AJ, Cash SS, Westover MB, Lam AD. Noninvasive Detection of Hippocampal Epileptiform Activity on Scalp Electroencephalogram. JAMA Neurol. 2022 06 01; 79(6):614-622. PMID: 35499837; PMCID: PMC9062772.
    Citations:    Fields:    Translation:Humans
  10. Vieluf S, Hasija T, Schreier PJ, El Atrache R, Hammond S, Mohammadpour Touserkani F, Sarkis RA, Loddenkemper T, Reinsberger C. Generalized tonic-clonic seizures are accompanied by changes of interrelations within the autonomic nervous system. Epilepsy Behav. 2021 Oct 05; 124:108321. PMID: 34624803.
    Citations:    Fields:    
  11. Kyriakopoulos P, Ding JZ, Niznick N, Lee JW, Sarkis R, Carpentier J, Fantaneanu TA. Resident Use of EEG Cap System to Rule Out Nonconvulsive Status Epilepticus. J Clin Neurophysiol. 2021 Sep 01; 38(5):426-431. PMID: 32501948.
    Citations: 1     Fields:    Translation:Humans
  12. Onorati F, Regalia G, Caborni C, LaFrance WC, Blum AS, Bidwell J, De Liso P, El Atrache R, Loddenkemper T, Mohammadpour-Touserkani F, Sarkis RA, Friedman D, Jeschke J, Picard R. Prospective Study of a Multimodal Convulsive Seizure Detection Wearable System on Pediatric and Adult Patients in the Epilepsy Monitoring Unit. Front Neurol. 2021; 12:724904. PMID: 34489858.
    Citations: 2     
  13. El Atrache R, Tamilia E, Amengual-Gual M, Mohammadpour Touserkani F, Yang Y, Wang X, Ufongene C, Sheehan T, Cantley S, Jackson M, Zhang B, Papadelis C, Sarkis RA, Loddenkemper T. Association between semiologic, autonomic, and electrographic seizure characteristics in children with generalized tonic-clonic seizures. Epilepsy Behav. 2021 09; 122:108228. PMID: 34388667.
    Citations:    Fields:    Translation:Humans
  14. Yang Y, Sarkis RA, Atrache RE, Loddenkemper T, Meisel C. Video-Based Detection of Generalized Tonic-Clonic Seizures Using Deep Learning. IEEE J Biomed Health Inform. 2021 08; 25(8):2997-3008. PMID: 33406048.
    Citations: 1     Fields:    Translation:Humans
  15. Johnson EL, Krauss GL, Kucharska-Newton A, Lam AD, Sarkis R, Gottesman RF. Mortality in Patients With Late-Onset Epilepsy: Results From the Atherosclerosis Risk in Communities Study. Neurology. 2021 09 14; 97(11):e1132-e1140. PMID: 34282048; PMCID: PMC8456359.
    Citations: 2     Fields:    Translation:Humans
  16. Olah M, Menon V, Habib N, Taga MF, Ma Y, Yung CJ, Cimpean M, Khairallah A, Coronas-Samano G, Sankowski R, Grün D, Kroshilina AA, Dionne D, Sarkis RA, Cosgrove GR, Helgager J, Golden JA, Pennell PB, Prinz M, Vonsattel JPG, Teich AF, Schneider JA, Bennett DA, Regev A, Elyaman W, Bradshaw EM, De Jager PL. Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease. Nat Commun. 2020 11 30; 11(1):6129. PMID: 33257666.
    Citations: 72     Fields:    Translation:HumansCells
  17. Regalia G, Gerboni G, Migliorini M, Lai M, Pham J, Puri N, Pavlova MK, Picard RW, Sarkis RA, Onorati F. Sleep assessment by means of a wrist actigraphy-based algorithm: agreement with polysomnography in an ambulatory study on older adults. Chronobiol Int. 2021 03; 38(3):400-414. PMID: 33213222.
    Citations: 3     Fields:    Translation:Humans
  18. Abou Jaoude M, Sun H, Pellerin KR, Pavlova M, Sarkis RA, Cash SS, Westover MB, Lam AD. Expert-level automated sleep staging of long-term scalp electroencephalography recordings using deep learning. Sleep. 2020 11 12; 43(11). PMID: 32478820.
    Citations: 7     Fields:    Translation:Humans
  19. Ge W, Jing J, An S, Herlopian A, Ng M, Struck AF, Appavu B, Johnson EL, Osman G, Haider HA, Karakis I, Kim JA, Halford JJ, Dhakar MB, Sarkis RA, Swisher CB, Schmitt S, Lee JW, Tabaeizadeh M, Rodriguez A, Gaspard N, Gilmore E, Herman ST, Kaplan PW, Pathmanathan J, Hong S, Rosenthal ES, Zafar S, Sun J, Brandon Westover M. Deep active learning for Interictal Ictal Injury Continuum EEG patterns. J Neurosci Methods. 2021 03 01; 351:108966. PMID: 33131680; PMCID: PMC8135050.
    Citations: 1     Fields:    Translation:Humans
  20. Sarkis RA, Beers L, Farah E, Al-Akaidi M, Zhang Y, Locascio JJ, Properzi MJ, Schultz AP, Chhatwal JP, Johnson KA, Sperling RA, B Pennell P, Marshall GA. The neurophysiology and seizure outcomes of late onset unexplained epilepsy. Clin Neurophysiol. 2020 11; 131(11):2667-2672. PMID: 32957039.
    Citations: 2     Fields:    Translation:Humans
  21. Lam AD, Sarkis RA, Pellerin KR, Jing J, Dworetzky BA, Hoch DB, Jacobs CS, Lee JW, Weisholtz DS, Zepeda R, Westover MB, Cole AJ, Cash SS. Association of epileptiform abnormalities and seizures in Alzheimer disease. Neurology. 2020 10 20; 95(16):e2259-e2270. PMID: 32764101.
    Citations: 21     Fields:    Translation:Humans
  22. El Atrache R, Tamilia E, Mohammadpour Touserkani F, Hammond S, Papadelis C, Kapur K, Jackson M, Bucciarelli B, Tsuboyama M, Sarkis RA, Loddenkemper T. Photoplethysmography: A measure for the function of the autonomic nervous system in focal impaired awareness seizures. Epilepsia. 2020 08; 61(8):1617-1626. PMID: 32710587.
    Citations: 3     Fields:    Translation:Humans
  23. Sarkis RA, Willment KC, Pennell PB, Marshall G. Late-onset unexplained epilepsy: What are we missing? Epilepsy Behav. 2019 10; 99:106478. PMID: 31481308.
    Citations: 8     Fields:    Translation:Humans
  24. Jacobs CS, Willment KC, Sarkis RA. Non-invasive Cognitive Enhancement in Epilepsy. Front Neurol. 2019; 10:167. PMID: 30890998; PMCID: PMC6413707.
    Citations:    
  25. Latreille V, Willment KC, Sarkis RA, Pavlova M. Neuropsychological correlates of obstructive sleep apnea severity in patients with epilepsy. Epileptic Disord. 2019 Feb 01; 21(1):78-86. PMID: 30782580.
    Citations:    Fields:    Translation:Humans
  26. Sarkis RA. Risk of Neuroleptic Malignant Syndrome in Encephalitides: Response to Caroff. J Neuropsychiatry Clin Neurosci. 2019; 31(4):400. PMID: 31613197.
    Citations:    Fields:    Translation:Humans
  27. Sarkis RA, Coffey MJ, Cooper JJ, Hassan I, Lennox B. Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Review of Psychiatric Phenotypes and Management Considerations: A Report of the American Neuropsychiatric Association Committee on Research. J Neuropsychiatry Clin Neurosci. 2019; 31(2):137-142. PMID: 30561283.
    Citations: 7     Fields:    Translation:Humans
  28. Sarkis RA, Meador KJ. Comment on: Use of Antiepileptic Drugs and Dementia Risk. J Am Geriatr Soc. 2018 09; 66(9):1852-1853. PMID: 30094829.
    Citations: 1     Fields:    Translation:Humans
  29. Latreille V, Baslet G, Sarkis R, Pavlova M, Dworetzky BA. Sleep in psychogenic nonepileptic seizures: Time to raise a red flag. Epilepsy Behav. 2018 09; 86:6-8. PMID: 30032094.
    Citations: 3     Fields:    Translation:Humans
  30. Sarkis RA, Goksen Y, Mu Y, Rosner B, Lee JW. Cognitive and fatigue side effects of anti-epileptic drugs: an analysis of phase III add-on trials. J Neurol. 2018 Sep; 265(9):2137-2142. PMID: 30003357.
    Citations: 5     Fields:    Translation:Humans
  31. Sarkis RA, McGinnis S, Rushia SN, Park S, Ansari EE, Willment KC. Growing older with drug-resistant epilepsy: cognitive and psychosocial outcomes. J Neurol. 2018 May; 265(5):1059-1064. PMID: 29478222.
    Citations: 4     Fields:    Translation:Humans
  32. Sarkis RA, Willment KC, Gale SA, Dworetzky BA. Recurrent Epileptic Auras As a Presenting Symptom of Alzheimer's Disease. Front Neurol. 2017; 8:360. PMID: 28790971; PMCID: PMC5522840.
    Citations: 3     
  33. Fantaneanu TA, Sarkis R, Avery K, Scirica BM, Hurwitz S, Henderson GV, Lee JW. Delayed Deterioration of EEG Background Rhythm Post-cardiac Arrest. Neurocrit Care. 2017 Jun; 26(3):411-419. PMID: 28004331.
    Citations: 5     Fields:    Translation:Humans
  34. Sarkis RA, Nicolas J, Lee JW. Tolerability of lacosamide or zonisamide in elderly patients with seizures. Seizure. 2017 Jul; 49:1-4. PMID: 28486158.
    Citations: 2     Fields:    Translation:Humans
  35. Gholipour T, Mitchell S, Sarkis RA, Chemali Z. The clinical and neurobehavioral course of Down syndrome and dementia with or without new-onset epilepsy. Epilepsy Behav. 2017 03; 68:11-16. PMID: 28109983.
    Citations: 12     Fields:    Translation:Humans
  36. Tolchin B, Lee JW, Pavlova M, Dworetzky BA, Sarkis RA. Diagnostic yield of ambulatory EEGs in the elderly. Clin Neurophysiol. 2017 07; 128(7):1350-1353. PMID: 28202220.
    Citations: 3     Fields:    Translation:Humans
  37. Sarkis RA, Alam J, Pavlova MK, Dworetzky BA, Pennell PB, Stickgold R, Bubrick EJ. Sleep-dependent memory consolidation in the epilepsy monitoring unit: A pilot study. Clin Neurophysiol. 2016 08; 127(8):2785-2790. PMID: 27417054.
    Citations: 1     Fields:    Translation:Humans
  38. Lee JW, Alam J, Llewellyn N, Hurwitz S, Bubrick EB, Sarkis RA, Weisholtz D, Yu H, Putta S, Dworetzky BA, Pennell PB. Open Label Trial of Add on Lacosamide Versus High Dose Levetiracetam Monotherapy in Patients With Breakthrough Seizures. Clin Neuropharmacol. 2016 May-Jun; 39(3):128-31. PMID: 26992155.
    Citations:    Fields:    Translation:Humans
  39. Sarkis RA, Dickerson BC, Cole AJ, Chemali ZN. Clinical and Neurophysiologic Characteristics of Unprovoked Seizures in Patients Diagnosed With Dementia. J Neuropsychiatry Clin Neurosci. 2016; 28(1):56-61. PMID: 26404175.
    Citations: 25     Fields:    Translation:Humans
  40. Sarkis RA, Thome-Souza S, Poh MZ, Llewellyn N, Klehm J, Madsen JR, Picard R, Pennell PB, Dworetzky BA, Loddenkemper T, Reinsberger C. Autonomic changes following generalized tonic clonic seizures: An analysis of adult and pediatric patients with epilepsy. Epilepsy Res. 2015 Sep; 115:113-8. PMID: 26220387.
    Citations: 17     Fields:    Translation:Humans
  41. Sarkis RA, Mays M, Isada C, Ahmed M. MRI findings in cryptococcal meningitis of the non-HIV population. Neurologist. 2015 Jan; 19(2):40-5. PMID: 25607331.
    Citations: 14     Fields:    Translation:Humans
  42. Reinsberger C, Sarkis R, Papadelis C, Doshi C, Perez DL, Baslet G, Loddenkemper T, Dworetzky BA. Autonomic changes in psychogenic nonepileptic seizures: toward a potential diagnostic biomarker? Clin EEG Neurosci. 2015 Jan; 46(1):16-25. PMID: 25780264.
    Citations: 8     Fields:    Translation:Humans
  43. Sarkis RA, Nehme R, Chemali ZN. Neuropsychiatric and seizure outcomes in nonparaneoplastic autoimmune limbic encephalitis. Epilepsy Behav. 2014 Oct; 39:21-5. PMID: 25171259.
    Citations: 8     Fields:    Translation:Humans
  44. sarkis rA, Kaur N, Camprodon JA. Current Behavioral Neuroscience Reports. Transcranial Direct Current Stimulation (tDCS): Modulation of Executive Function in Health and Disease. 2014.
  45. Forgacs PB, Sarkis R, Folkerth R, Golby A, Hsu L, Bubrick EJ, Dworetzky BA. Focal cortical dysplasia IIb presenting as slowly progressive aphasia mimicking a brain tumor. Seizure. 2014 Feb; 23(2):161-3. PMID: 24148976.
    Citations: 2     Fields:    Translation:HumansCells
  46. Sarkis RA, Lee JW. Quantitative EEG in hospital encephalopathy: review and microstate analysis. J Clin Neurophysiol. 2013 Oct; 30(5):526-30. PMID: 24084185.
    Citations: 2     Fields:    Translation:Humans
  47. Sarkis RA, Pietras AC, Cheung A, Baslet G, Dworetzky B. Neuropsychological and psychiatric outcomes in poorly controlled idiopathic generalized epilepsy. Epilepsy Behav. 2013 Sep; 28(3):370-3. PMID: 23832134.
    Citations: 4     Fields:    Translation:Humans
  48. Sarkis RA, Busch RM, Floden D, Chapin JS, Kalman Kenney C, Jehi L, Ruggieri P, Najm I. Predictors of decline in verbal fluency after frontal lobe epilepsy surgery. Epilepsy Behav. 2013 May; 27(2):326-9. PMID: 23524470.
    Citations: 4     Fields:    Translation:Humans
  49. Sarkis RA, Jehi L, Bingaman W, Najm IM. Seizure worsening and its predictors after epilepsy surgery. Epilepsia. 2012 Oct; 53(10):1731-8. PMID: 22958128.
    Citations: 6     Fields:    Translation:Humans
  50. Sarkis RA, Jehi L, Silveira D, Janigro D, Najm I. Patients with generalised epilepsy have a higher white blood cell count than patients with focal epilepsy. Epileptic Disord. 2012 Mar; 14(1):57-63. PMID: 22433317.
    Citations: 4     Fields:    Translation:Humans
  51. Sarkis RA, Jehi L, Najm IM, Kotagal P, Bingaman WE. Seizure outcomes following multilobar epilepsy surgery. Epilepsia. 2012 Jan; 53(1):44-50. PMID: 21955142.
    Citations: 15     Fields:    Translation:HumansPHPublic Health
  52. Sarkis R, Saadé N, Atweh S, Jabbur S, Al-Amin H. Chronic dizocilpine or apomorphine and development of neuropathy in two rat models I: behavioral effects and role of nucleus accumbens. Exp Neurol. 2011 Mar; 228(1):19-29. PMID: 21146525.
    Citations: 13     Fields:    Translation:Animals
  53. Al-Amin H, Sarkis R, Atweh S, Jabbur S, Saadé N. Chronic dizocilpine or apomorphine and development of neuropathy in two animal models II: effects on brain cytokines and neurotrophins. Exp Neurol. 2011 Mar; 228(1):30-40. PMID: 21075106.
    Citations: 25     Fields:    Translation:Animals
  54. Sarkis RA, Jehi LE, Bingaman WE, Najm IM. Surgical outcome following resection of rolandic focal cortical dysplasia. Epilepsy Res. 2010 Aug; 90(3):240-7. PMID: 20538428.
    Citations: 8     Fields:    Translation:Humans
  55. Sarkis R, Wyllie E, Burgess RC, Loddenkemper T. Neuroimaging findings in children with benign focal epileptiform discharges. Epilepsy Res. 2010 Jun; 90(1-2):91-8. PMID: 20418066.
    Citations: 3     Fields:    Translation:Humans
  56. Jehi L, Sarkis R, Bingaman W, Kotagal P, Najm I. When is a postoperative seizure equivalent to "epilepsy recurrence" after epilepsy surgery? Epilepsia. 2010 Jun; 51(6):994-1003. PMID: 20384726.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  57. Sarkis RA, Loddenkemper T, Burgess RC, Wyllie E. Childhood absence epilepsy in patients with benign focal epileptiform discharges. Pediatr Neurol. 2009 Dec; 41(6):428-34. PMID: 19931164.
    Citations: 2     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact contactcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
sarkis's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (171)
Explore
_
Co-Authors (48)
Explore
_
Similar People (59)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.