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Roy Jason Soberman, M.D.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R01CA193520 (SOBERMAN, ROY) Feb 4, 2016 - Jan 31, 2021
    NIH
    The Role of lncRNA MEG3 in Clinically Non-functioning Pituitary Adenomas
    Role: Principal Investigator
  2. S10RR027931 (SOBERMAN, ROY) Apr 29, 2010 - Apr 28, 2012
    NIH
    A System for FLIM Microscopy
    Role: Principal Investigator
  3. R01AI068871 (SOBERMAN, ROY) Apr 4, 2007 - Mar 31, 2014
    NIH
    Leukotrienes and Lung Inflammation
    Role: Principal Investigator
  4. R56AI068871 (SOBERMAN, ROY) Mar 15, 2006 - Feb 28, 2007
    NIH
    Leukotrienes and Lung Inflammation
    Role: Principal Investigator
  5. R01DK062472 (SOBERMAN, ROY) Jul 1, 2002 - Oct 30, 2020
    NIH
    Role of B7-1 in Podocytes in Pathogenesis of Proteinuria
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Barrachina F, Ottino K, Tu LJ, Soberman RJ, Brown D, Breton S, Battistone MA. CX3CR1 deficiency leads to impairment of immune surveillance in the epididymis. Cell Mol Life Sci. 2022 Dec 23; 80(1):15. PMID: 36550225; PMCID: PMC9948740.
    Citations:    Fields:    Translation:HumansAnimalsCells
  2. Yasuhara T, Xing YH, Bauer NC, Lee L, Dong R, Yadav T, Soberman RJ, Rivera MN, Zou L. Condensates induced by transcription inhibition localize active chromatin to nucleoli. Mol Cell. 2022 08 04; 82(15):2738-2753.e6. PMID: 35662392; PMCID: PMC9357099.
    Citations: 2     Fields:    Translation:Cells
  3. Zhao W, Jiang X, Weisenthal K, Ma J, Botticelli EM, Zhou Y, Hedley-Whyte ET, Wang B, Swearingen B, Soberman RJ, Klibanski A, Zhang X. High Histone Deacetylase 2/3 Expression in Non-Functioning Pituitary Tumors. Front Oncol. 2022; 12:875122. PMID: 35646715; PMCID: PMC9136140.
    Citations: 1     
  4. Zhou J, Hu Y, Zhu W, Nie C, Zhao W, Faje AT, Labelle KE, Swearingen B, Lee H, Hedley-Whyte ET, Zhang X, Jones PS, Miller KK, Klibanski A, Zhou Y, Soberman RJ. Sprouting Angiogenesis in Human Pituitary Adenomas. Front Oncol. 2022; 12:875219. PMID: 35600354; PMCID: PMC9117625.
    Citations:    
  5. Xi Z, Jones PS, Mikamoto M, Jiang X, Faje AT, Nie C, Labelle KE, Zhou Y, Miller KK, Soberman RJ, Zhang X. The Upregulation of Molecules Related to Tumor Immune Escape in Human Pituitary Adenomas. Front Endocrinol (Lausanne). 2021; 12:726448. PMID: 34745002; PMCID: PMC8566912.
    Citations: 2     Fields:    Translation:Humans
  6. Islam MR, Valaris S, Young MF, Haley EB, Luo R, Bond SF, Mazuera S, Kitchen RR, Caldarone BJ, Bettio LEB, Christie BR, Schmider AB, Soberman RJ, Besnard A, Jedrychowski MP, Kim H, Tu H, Kim E, Choi SH, Tanzi RE, Spiegelman BM, Wrann CD. Author Correction: Exercise hormone irisin is a critical regulator of cognitive function. Nat Metab. 2021 Oct; 3(10):1432. PMID: 34621079.
    Citations: 1     Fields:    
  7. Islam MR, Valaris S, Young MF, Haley EB, Luo R, Bond SF, Mazuera S, Kitchen RR, Caldarone BJ, Bettio LEB, Christie BR, Schmider AB, Soberman RJ, Besnard A, Jedrychowski MP, Kim H, Tu H, Kim E, Choi SH, Tanzi RE, Spiegelman BM, Wrann CD. Exercise hormone irisin is a critical regulator of cognitive function. Nat Metab. 2021 08; 3(8):1058-1070. PMID: 34417591.
    Citations: 41     Fields:    Translation:Animals
  8. Bauer NC, Yang A, Wang X, Zhou Y, Klibanski A, Soberman RJ. A cross-nearest neighbor/Monte Carlo algorithm for single-molecule localization microscopy defines interactions between p53, Mdm2, and MEG3. J Biol Chem. 2021 Jan-Jun; 296:100540. PMID: 33722609.
    Citations: 2     Fields:    Translation:HumansCells
  9. Shah A, Dagdeviren S, Lewandowski JP, Schmider AB, Ricci-Blair EM, Natarajan N, Hundal H, Noh HL, Friedline RH, Vidoudez C, Kim JK, Wagers AJ, Soberman RJ, Lee RT. Thioredoxin Interacting Protein Is Required for a Chronic Energy-Rich Diet to Promote Intestinal Fructose Absorption. iScience. 2020 Sep 02; 23(9):101521. PMID: 32927265.
    Citations: 5     
  10. Schmider AB, Bauer NC, Sunwoo H, Godin MD, Ellis GE, Lee JT, Nigrovic PA, Soberman RJ. Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils. J Biol Chem. 2020 04 24; 295(17):5761-5770. PMID: 32152223.
    Citations: 1     Fields:    Translation:AnimalsCells
  11. Zhu W, Botticelli EM, Kery RE, Mao Y, Wang X, Yang A, Wang X, Zhou J, Zhang X, Soberman RJ, Klibanski A, Zhou Y. Meg3-DMR, not the Meg3 gene, regulates imprinting of the Dlk1-Dio3 locus. Dev Biol. 2019 11 01; 455(1):10-18. PMID: 31301299.
    Citations: 4     Fields:    Translation:AnimalsCells
  12. Cunin P, Lee PY, Kim E, Schmider AB, Cloutier N, Pare A, Gunzer M, Soberman RJ, Lacroix S, Boilard E, Lefort CT, Nigrovic PA. Differential attenuation of ß2 integrin-dependent and -independent neutrophil migration by Ly6G ligation. Blood Adv. 2019 02 12; 3(3):256-267. PMID: 30696624; PMCID: PMC6373735.
    Citations: 9     Fields:    Translation:AnimalsCells
  13. Schmider AB, Vaught M, Bauer NC, Elliott HL, Godin MD, Ellis GE, Nigrovic PA, Soberman RJ. The organization of leukotriene biosynthesis on the nuclear envelope revealed by single molecule localization microscopy and computational analyses. PLoS One. 2019; 14(2):e0211943. PMID: 30735559; PMCID: PMC6368329.
    Citations: 6     Fields:    Translation:AnimalsCells
  14. Bai M, Grieshaber-Bouyer R, Wang J, Schmider AB, Wilson ZS, Zeng L, Halyabar O, Godin MD, Nguyen HN, Levescot A, Cunin P, Lefort CT, Soberman RJ, Nigrovic PA. CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation. Blood. 2017 11 09; 130(19):2092-2100. PMID: 28807980; PMCID: PMC5680608.
    Citations: 56     Fields:    Translation:HumansCells
  15. Dotimas JR, Lee AW, Schmider AB, Carroll SH, Shah A, Bilen J, Elliott KR, Myers RB, Soberman RJ, Yoshioka J, Lee RT. Diabetes regulates fructose absorption through thioredoxin-interacting protein. Elife. 2016 10 11; 5. PMID: 27725089.
    Citations: 24     Fields:    Translation:AnimalsCells
  16. Pickett EK, Koffie RM, Wegmann S, Henstridge CM, Herrmann AG, Colom-Cadena M, Lleo A, Kay KR, Vaught M, Soberman R, Walsh DM, Hyman BT, Spires-Jones TL. Non-Fibrillar Oligomeric Amyloid-ß within Synapses. J Alzheimers Dis. 2016 05 30; 53(3):787-800. PMID: 27258414.
    Citations: 34     Fields:    Translation:AnimalsCells
  17. Park SY, Yang JS, Schmider AB, Soberman RJ, Hsu VW. Coordinated regulation of bidirectional COPI transport at the Golgi by CDC42. Nature. 2015 May 28; 521(7553):529-32. PMID: 25945738.
    Citations: 51     Fields:    Translation:HumansCells
  18. Vaine CA, Soberman RJ. The CD200-CD200R1 inhibitory signaling pathway: immune regulation and host-pathogen interactions. Adv Immunol. 2014; 121:191-211. PMID: 24388216.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  19. Armata IA, Balaj L, Kuster JK, Zhang X, Tsai S, Armatas AA, Multhaupt-Buell TJ, Soberman R, Breakefield XO, Ichinose H, Sharma N. Dopa-responsive dystonia: functional analysis of single nucleotide substitutions within the 5' untranslated GCH1 region. PLoS One. 2013; 8(10):e76975. PMID: 24124602.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  20. Azcutia V, Routledge M, Williams MR, Newton G, Frazier WA, Manica A, Croce KJ, Parkos CA, Schmider AB, Turman MV, Soberman RJ, Luscinskas FW. CD47 plays a critical role in T-cell recruitment by regulation of LFA-1 and VLA-4 integrin adhesive functions. Mol Biol Cell. 2013 Nov; 24(21):3358-68. PMID: 24006483.
    Citations: 39     Fields:    Translation:HumansAnimalsCells
  21. Beckett EL, Stevens RL, Jarnicki AG, Kim RY, Hanish I, Hansbro NG, Deane A, Keely S, Horvat JC, Yang M, Oliver BG, van Rooijen N, Inman MD, Adachi R, Soberman RJ, Hamadi S, Wark PA, Foster PS, Hansbro PM. A new short-term mouse model of chronic obstructive pulmonary disease identifies a role for mast cell tryptase in pathogenesis. J Allergy Clin Immunol. 2013 Mar; 131(3):752-62. PMID: 23380220; PMCID: PMC4060894.
    Citations: 102     Fields:    Translation:AnimalsCells
  22. Soberman RJ, MacKay CR, Vaine CA, Ryan GB, Cerny AM, Thompson MR, Nikolic B, Primo V, Christmas P, Sheiffele P, Aronov L, Knipe DM, Kurt-Jones EA. CD200R1 supports HSV-1 viral replication and licenses pro-inflammatory signaling functions of TLR2. PLoS One. 2012; 7(10):e47740. PMID: 23082204.
    Citations: 16     Fields:    Translation:AnimalsCells
  23. Bair AM, Turman MV, Vaine CA, Panettieri RA, Soberman RJ. The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer. Mol Biol Cell. 2012 Nov; 23(22):4456-64. PMID: 23015755.
    Citations: 20     Fields:    Translation:AnimalsCells
  24. Wang JX, Bair AM, King SL, Shnayder R, Huang YF, Shieh CC, Soberman RJ, Fuhlbrigge RC, Nigrovic PA. Ly6G ligation blocks recruitment of neutrophils via a ß2-integrin-dependent mechanism. Blood. 2012 Aug 16; 120(7):1489-98. PMID: 22661700; PMCID: PMC3423786.
    Citations: 55     Fields:    Translation:AnimalsCells
  25. Damera G, Druey KM, Cooper PR, Krymskaya VP, Soberman RJ, Amrani Y, Hoshi T, Brightling CE, Panettieri RA. An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma. PLoS One. 2012; 7(1):e28504. PMID: 22253691.
    Citations: 16     Fields:    Translation:HumansCells
  26. Chen M, Lam BK, Luster AD, Zarini S, Murphy RC, Bair AM, Soberman RJ, Lee DM. Joint tissues amplify inflammation and alter their invasive behavior via leukotriene B4 in experimental inflammatory arthritis. J Immunol. 2010 Nov 01; 185(9):5503-11. PMID: 20876351; PMCID: PMC3690310.
    Citations: 15     Fields:    Translation:AnimalsCells
  27. Cooper PR, Mesaros AC, Zhang J, Christmas P, Stark CM, Douaidy K, Mittelman MA, Soberman RJ, Blair IA, Panettieri RA. 20-HETE mediates ozone-induced, neutrophil-independent airway hyper-responsiveness in mice. PLoS One. 2010 Apr 20; 5(4):e10235. PMID: 20422032.
    Citations: 31     Fields:    Translation:AnimalsCells
  28. Mandal AK, Jones PB, Bair AM, Christmas P, Miller D, Yamin TT, Wisniewski D, Menke J, Evans JF, Hyman BT, Bacskai B, Chen M, Lee DM, Nikolic B, Soberman RJ. The nuclear membrane organization of leukotriene synthesis. Proc Natl Acad Sci U S A. 2008 Dec 23; 105(51):20434-9. PMID: 19075240.
    Citations: 43     Fields:    Translation:AnimalsCells
  29. Soberman RJ, Christmas P. Revisiting prostacyclin: new directions in pulmonary fibrosis and inflammation. Am J Physiol Lung Cell Mol Physiol. 2006 Aug; 291(2):L142-3. PMID: 16581828.
    Citations: 6     Fields:    Translation:Animals
  30. Christmas P, Tolentino K, Primo V, Berry KZ, Murphy RC, Chen M, Lee DM, Soberman RJ. Cytochrome P-450 4F18 is the leukotriene B4 omega-1/omega-2 hydroxylase in mouse polymorphonuclear leukocytes: identification as the functional orthologue of human polymorphonuclear leukocyte CYP4F3A in the down-regulation of responses to LTB4. J Biol Chem. 2006 Mar 17; 281(11):7189-96. PMID: 16380383.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  31. Mandal AK, Skoch J, Bacskai BJ, Hyman BT, Christmas P, Miller D, Yamin TT, Xu S, Wisniewski D, Evans JF, Soberman RJ. The membrane organization of leukotriene synthesis. Proc Natl Acad Sci U S A. 2004 Apr 27; 101(17):6587-92. PMID: 15084748; PMCID: PMC404089.
    Citations: 28     Fields:    Translation:HumansCells
  32. Christmas P, Carlesso N, Shang H, Cheng SM, Weber BM, Preffer FI, Scadden DT, Soberman RJ. Myeloid expression of cytochrome P450 4F3 is determined by a lineage-specific alternative promoter. J Biol Chem. 2003 Jul 04; 278(27):25133-42. PMID: 12709424.
    Citations: 5     Fields:    Translation:HumansCells
  33. Soberman RJ, Christmas P. The organization and consequences of eicosanoid signaling. J Clin Invest. 2003 Apr; 111(8):1107-13. PMID: 12697726; PMCID: PMC152944.
    Citations: 54     Fields:    Translation:HumansAnimals
  34. Soberman RJ. The expanding network of redox signaling: new observations, complexities, and perspectives. J Clin Invest. 2003 Mar; 111(5):571-4. PMID: 12618508; PMCID: PMC151913.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  35. Christmas P, Weber BM, McKee M, Brown D, Soberman RJ. Membrane localization and topology of leukotriene C4 synthase. J Biol Chem. 2002 Aug 09; 277(32):28902-8. PMID: 12023288.
    Citations: 15     Fields:    Translation:AnimalsCells
  36. Henne KR, Kunze KL, Zheng YM, Christmas P, Soberman RJ, Rettie AE. Covalent linkage of prosthetic heme to CYP4 family P450 enzymes. Biochemistry. 2001 Oct 30; 40(43):12925-31. PMID: 11669629.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  37. Christmas P, Jones JP, Patten CJ, Rock DA, Zheng Y, Cheng SM, Weber BM, Carlesso N, Scadden DT, Rettie AE, Soberman RJ. Alternative splicing determines the function of CYP4F3 by switching substrate specificity. J Biol Chem. 2001 Oct 12; 276(41):38166-72. PMID: 11461919.
    Citations: 33     Fields:    Translation:HumansCells
  38. Fitzpatrick FA, Soberman R. Regulated formation of eicosanoids. J Clin Invest. 2001 Jun; 107(11):1347-51. PMID: 11390414; PMCID: PMC209329.
    Citations: 50     Fields:    Translation:HumansAnimals
  39. Christmas P, Fox JW, Ursino SR, Soberman RJ. Differential localization of 5- and 15-lipoxygenases to the nuclear envelope in RAW macrophages. J Biol Chem. 1999 Sep 03; 274(36):25594-8. PMID: 10464294.
    Citations: 4     Fields:    Translation:AnimalsCells
  40. Christmas P, Ursino SR, Fox JW, Soberman RJ. Expression of the CYP4F3 gene. tissue-specific splicing and alternative promoters generate high and low K(m) forms of leukotriene B(4) omega-hydroxylase. J Biol Chem. 1999 Jul 23; 274(30):21191-9. PMID: 10409674.
    Citations: 12     Fields:    Translation:HumansCells
  41. Puder M, Soberman RJ. Glutathione conjugates recognize the Rossmann fold of glyceraldehyde-3-phosphate dehydrogenase. J Biol Chem. 1997 Apr 18; 272(16):10936-40. PMID: 9099752.
    Citations: 3     Fields:    Translation:HumansCells
  42. Kim J, Puder M, Soberman RJ. Joining of DNA fragments by repeated cycles of denaturation, annealing and extension. Biotechniques. 1996 Jun; 20(6):954-5. PMID: 8780860.
    Citations: 3     Fields:    Translation:Cells
  43. Penrose JF, Gagnon L, Goppelt-Struebe M, Myers P, Lam BK, Jack RM, Austen KF, Soberman RJ. Purification of human leukotriene C4 synthase. Proc Natl Acad Sci U S A. 1992 Dec 01; 89(23):11603-6. PMID: 1454853; PMCID: PMC50601.
    Citations: 10     Fields:    Translation:HumansCells
  44. Haberman J, Karwa G, Greenstein SM, Soberman R, Glicklich D, Tellis V, Melman A. Male fertility in cyclosporine-treated renal transplant patients. J Urol. 1991 Feb; 145(2):294-6. PMID: 1988720.
    Citations: 6     Fields:    Translation:Humans
  45. Lewis RA, Austen KF, Soberman RJ. Leukotrienes and other products of the 5-lipoxygenase pathway. Biochemistry and relation to pathobiology in human diseases. N Engl J Med. 1990 Sep 06; 323(10):645-55. PMID: 2166915.
    Citations: 226     Fields:    Translation:Humans
  46. Lam BK, Gagnon L, Austen KF, Soberman RJ. The mechanism of leukotriene B4 export from human polymorphonuclear leukocytes. J Biol Chem. 1990 Aug 15; 265(23):13438-41. PMID: 2166027.
    Citations: 10     Fields:    Translation:HumansCells
  47. Caulfield JP, Hein A, Rothenberg ME, Owen WF, Soberman RJ, Stevens RL, Austen KF. A morphometric study of normodense and hypodense human eosinophils that are derived in vivo and in vitro. Am J Pathol. 1990 Jul; 137(1):27-41. PMID: 2196816; PMCID: PMC1877686.
    Citations: 8     Fields:    Translation:HumansCells
  48. Dustin LB, Shea CM, Soberman RJ, Lu CY. Docosahexaenoic acid, a constituent of rodent fetal serum and fish oil diets, inhibits acquisition of macrophage tumoricidal function. J Immunol. 1990 Jun 15; 144(12):4888-97. PMID: 2141046.
    Citations: 5     Fields:    Translation:Cells
  49. Soberman RJ. Purification and properties of leukotriene C4 synthase from guinea pig lung microsomes. Methods Enzymol. 1990; 187:335-7. PMID: 2172737.
    Citations:    Fields:    Translation:AnimalsCells
  50. Soberman RJ. Cytochrome P-450LTB and inactivation of leukotriene B4. Methods Enzymol. 1990; 187:319-24. PMID: 2172735.
    Citations:    Fields:    Translation:HumansCells
  51. Sutyak J, Austen KF, Soberman RJ. Identification of an aldehyde dehydrogenase in the microsomes of human polymorphonuclear leukocytes that metabolizes 20-aldehyde leukotriene B4. J Biol Chem. 1989 Sep 05; 264(25):14818-23. PMID: 2549038.
    Citations: 3     Fields:    Translation:HumansCells
  52. Lam BK, Owen WF, Austen KF, Soberman RJ. The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils. J Biol Chem. 1989 Aug 05; 264(22):12885-9. PMID: 2753893.
    Citations: 25     Fields:    Translation:HumansCells
  53. Owen WF, Rothenberg ME, Petersen J, Weller PF, Silberstein D, Sheffer AL, Stevens RL, Soberman RJ, Austen KF. Interleukin 5 and phenotypically altered eosinophils in the blood of patients with the idiopathic hypereosinophilic syndrome. J Exp Med. 1989 Jul 01; 170(1):343-8. PMID: 2787385; PMCID: PMC2189380.
    Citations: 44     Fields:    Translation:HumansCells
  54. Reisfeld D, Matas AJ, Tellis VA, Sprayragen S, Bakal C, Soberman R, Glicklich D, Veith FJ. Late follow-up of percutaneous transluminal angioplasty for treatment of transplant renal artery stenosis. Transplant Proc. 1989 Feb; 21(1 Pt 2):1955-6. PMID: 2523597.
    Citations: 1     Fields:    Translation:Humans
  55. Matas A, Tellis V, Quinn T, Mallis M, Glicklich D, Senitzer DS, Soberman R. Long-term results of O-antigen match cadaver transplants--a single-institution study. Transplant Proc. 1989 Feb; 21(1 Pt 1):682. PMID: 2650221.
    Citations:    Fields:    Translation:Humans
  56. Tellis V, Matas A, Soberman R, Principe A, Quinn T, Mallis M, Veith F. Long-term patient survival after cadaver renal transplantation. Transplant Proc. 1989 Feb; 21(1 Pt 2):2186. PMID: 2652704.
    Citations:    Fields:    Translation:Humans
  57. Glicklich D, Tellis VA, Matas AJ, Mallis M, Quinn T, Soberman R, Veith FJ. No association between post-transplant erythrocytosis, thromboembolic events, and cyclosporine therapy. Transplant Proc. 1989 Feb; 21(1 Pt 2):2141-2. PMID: 2652691.
    Citations:    Fields:    Translation:Humans
  58. Soberman RJ, Austen KF. The cell biology and biochemistry of leukotriene C4 biosynthesis. Adv Prostaglandin Thromboxane Leukot Res. 1989; 19:21-5. PMID: 2526470.
    Citations: 3     Fields:    Translation:HumansAnimals
  59. Soberman RJ. Enzymes of the 5-lipoxygenase pathway. Prog Clin Biol Res. 1989; 297:39-43; discussion 43-4. PMID: 2555821.
    Citations:    Fields:    Translation:HumansAnimalsCells
  60. Tellis VA, Matas AJ, Senitzer D, Louis P, Glicklich D, Soberman R, Veith FJ. Successful transplantation after conversion of a positive crossmatch to negative by dissociation of IgM antibody. Transplantation. 1989 Jan; 47(1):127-9. PMID: 2643222.
    Citations: 3     Fields:    Translation:HumansCells
  61. Glicklich D, Gruber HE, Matas AJ, Tellis VA, Karwa G, Finley K, Salem C, Soberman R, Seegmiller JE. 2,8-dihydroxyadenine urolithiasis: report of a case first diagnosed after renal transplant. Q J Med. 1988 Oct; 68(258):785-93. PMID: 3077470.
    Citations: 9     Fields:    Translation:Humans
  62. Rothenberg ME, Pomerantz JL, Owen WF, Avraham S, Soberman RJ, Austen KF, Stevens RL. Characterization of a human eosinophil proteoglycan, and augmentation of its biosynthesis and size by interleukin 3, interleukin 5, and granulocyte/macrophage colony stimulating factor. J Biol Chem. 1988 Sep 25; 263(27):13901-8. PMID: 2458354.
    Citations: 22     Fields:    Translation:HumansCells
  63. Stein M, Matas AJ, Tellis VA, Quinn TA, Karwa GL, Glicklich D, Soberman R, Veith FJ. When further ALG administration becomes futile. Transplantation. 1988 Sep; 46(3):464-6. PMID: 3047939.
    Citations:    Fields:    Translation:Humans
  64. Soberman RJ, Sutyak JP, Okita RT, Wendelborn DF, Roberts LJ, Austen KF. The identification and formation of 20-aldehyde leukotriene B4. J Biol Chem. 1988 Jun 15; 263(17):7996-8002. PMID: 2836406.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  65. Rothenberg ME, Owen WF, Silberstein DS, Woods J, Soberman RJ, Austen KF, Stevens RL. Human eosinophils have prolonged survival, enhanced functional properties, and become hypodense when exposed to human interleukin 3. J Clin Invest. 1988 Jun; 81(6):1986-92. PMID: 3133397; PMCID: PMC442652.
    Citations: 72     Fields:    Translation:HumansAnimalsCells
  66. Matas AJ, Quinn TA, Tellis VA, Glicklich D, Soberman R, Veith FJ. The effect of the referring dialysis center on renal transplant results. Transplantation. 1988 May; 45(5):894-8. PMID: 3285533.
    Citations:    Fields:    Translation:Humans
  67. Yoshimoto T, Soberman RJ, Spur B, Austen KF. Properties of highly purified leukotriene C4 synthase of guinea pig lung. J Clin Invest. 1988 Mar; 81(3):866-71. PMID: 3343345; PMCID: PMC442538.
    Citations: 18     Fields:    Translation:AnimalsCells
  68. Badwey JA, Robinson JM, Horn W, Soberman RJ, Karnovsky MJ, Karnovsky ML. Synergistic stimulation of neutrophils. Possible involvement of 5-hydroxy-6,8,11,14-eicosatetraenoate in superoxide release. J Biol Chem. 1988 Feb 25; 263(6):2779-86. PMID: 2830263.
    Citations: 12     Fields:    Translation:AnimalsCells
  69. Matas AJ, Tellis VA, Quinn TA, Glicklich D, Soberman R, Veith FJ. Successful transplantation of highly sensitized patients without regard to HLA matching. Transplantation. 1988 Feb; 45(2):338-42. PMID: 3278426.
    Citations: 2     Fields:    Translation:Humans
  70. Matas AJ, Tellis VA, Quinn TA, Glicklich D, Soberman R, Veith FJ. Individualization of immediate posttransplant immunosuppression. The value of antilymphocyte globulin in patients with delayed graft function. Transplantation. 1988 Feb; 45(2):406-9. PMID: 3278434.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  71. Soberman RJ, Okita RT. Leukotriene B4 20-hydroxylase of human polymorphonuclear leukocytes. Methods Enzymol. 1988; 163:349-53. PMID: 3070301.
    Citations:    Fields:    Translation:HumansCells
  72. Soberman RJ. 5- and 15(omega-6)-lipoxygenases from human polymorphonuclear leukocytes. Methods Enzymol. 1988; 163:344-9. PMID: 3070300.
    Citations: 1     Fields:    Translation:HumansCells
  73. Austen F, Soberman RJ. Perspectives on additional areas for research in leukotrienes. Ann N Y Acad Sci. 1988; 524:xi-xxv. PMID: 2837946.
    Citations:    Fields:    Translation:HumansAnimalsCells
  74. Soberman RJ, Yoshimoto T. Leukotriene C4 synthase from rat basophilic leukemia cell microsomes. Methods Enzymol. 1988; 163:353-7. PMID: 3237082.
    Citations:    Fields:    Translation:AnimalsCells
  75. Matas AJ, Tellis VA, Quinn TA, Glicklich D, Soberman R, Veith FJ. Timing of cyclosporine administration in patients with delayed graft function. J Surg Res. 1987 Dec; 43(6):489-94. PMID: 3320528.
    Citations:    Fields:    Translation:Humans
  76. Okita RT, Soberman RJ, Bergholte JM, Masters BS, Hayes R, Murphy RC. omega-Hydroxylation of 15-hydroxyeicosatetraenoic acid by lung microsomes from pregnant rabbits. Mol Pharmacol. 1987 Nov; 32(5):706-9. PMID: 3683367.
    Citations: 2     Fields:    Translation:AnimalsCells
  77. Soberman RJ, Okita RT, Fitzsimmons B, Rokach J, Spur B, Austen KF. Stereochemical requirements for substrate specificity of LTB4 20-hydroxylase. J Biol Chem. 1987 Sep 15; 262(26):12421-7. PMID: 3040745.
    Citations: 3     Fields:    Translation:HumansCells
  78. Bergholte JM, Soberman RJ, Hayes R, Murphy RC, Okita RT. Oxidation of 15-hydroxyeicosatetraenoic acid and other hydroxy fatty acids by lung prostaglandin dehydrogenase. Arch Biochem Biophys. 1987 Sep; 257(2):444-50. PMID: 3662534.
    Citations: 10     Fields:    Translation:AnimalsCells
  79. Rothenberg ME, Owen WF, Silberstein DS, Soberman RJ, Austen KF, Stevens RL. Eosinophils cocultured with endothelial cells have increased survival and functional properties. Science. 1987 Aug 07; 237(4815):645-7. PMID: 3110954.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  80. Owen WF, Rothenberg ME, Silberstein DS, Gasson JC, Stevens RL, Austen KF, Soberman RJ. Regulation of human eosinophil viability, density, and function by granulocyte/macrophage colony-stimulating factor in the presence of 3T3 fibroblasts. J Exp Med. 1987 Jul 01; 166(1):129-41. PMID: 3110347; PMCID: PMC2188636.
    Citations: 72     Fields:    Translation:HumansAnimalsCells
  81. Heavey DJ, Soberman RJ, Lewis RA, Spur B, Austen KF. Critical considerations in the development of an assay for sulfidopeptide leukotrienes in plasma. Prostaglandins. 1987 May; 33(5):693-708. PMID: 3035620.
    Citations: 7     Fields:    Translation:Humans
  82. Tellis VA, Matas AJ, Quinn TA, Glicklich D, Weiss RJ, Soberman RJ, Veith FJ. Antilymphoblast globulin treatment of steroid-resistant rejection in cyclosporine-immunosuppressed renal transplant recipients. Transplant Proc. 1987 Feb; 19(1 Pt 3):1892. PMID: 3274447.
    Citations: 1     Fields:    Translation:Humans
  83. Owen WF, Soberman RJ, Yoshimoto T, Sheffer AL, Lewis RA, Austen KF. Synthesis and release of leukotriene C4 by human eosinophils. J Immunol. 1987 Jan 15; 138(2):532-8. PMID: 3025300.
    Citations: 27     Fields:    Translation:HumansCells
  84. Glicklich D, Matas AJ, Sablay LB, Senitzer D, Tellis VA, Soberman R, Veith FJ. Recurrent membranoproliferative glomerulonephritis type 1 in successive renal transplants. Am J Nephrol. 1987; 7(2):143-9. PMID: 3300338.
    Citations: 1     Fields:    Translation:Humans
  85. Silberstein DS, Owen WF, Gasson JC, DiPersio JF, Golde DW, Bina JC, Soberman R, Austen KF, David JR. Enhancement of human eosinophil cytotoxicity and leukotriene synthesis by biosynthetic (recombinant) granulocyte-macrophage colony-stimulating factor. J Immunol. 1986 Nov 15; 137(10):3290-4. PMID: 3095427.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  86. Gordon MJ, White R, Matas AJ, Tellis VA, Glicklich D, Quinn T, Soberman R, Veith FJ. Renal transplantation in patients with a history of heroin abuse. Transplantation. 1986 Nov; 42(5):556-7. PMID: 3538540.
    Citations: 1     Fields:    Translation:Humans
  87. Massicot JG, Soberman RJ, Ackerman NR, Heavey D, Roberts LJ, Austen KF. Workshop: Potential therapeutic uses of inhibitors of leukotriene generation and function. June 23, 1986, Bethesda, Maryland. Sponsored by the National Institute of Allergy and Infectious Diseases and the World Health Organization Collaborating Center for Allergic Diseases. Prostaglandins. 1986 Oct; 32(4):481-94. PMID: 3025934.
    Citations: 1     Fields:    Translation:Animals
  88. Wengerter K, Matas AJ, Tellis VA, Quinn T, Soberman R, Veith FJ. Transplantation of pediatric donor kidneys to adult recipients. Is there a critical donor age? Ann Surg. 1986 Aug; 204(2):172-5. PMID: 3527090; PMCID: PMC1251258.
    Citations: 5     Fields:    Translation:Humans
  89. Matas AJ, Tellis VA, Quinn T, Glichlick D, Soberman R, Weiss R, Karwa G, Veith FJ. ALG treatment of steroid-resistant rejection in patients receiving cyclosporine. Transplantation. 1986 May; 41(5):579-83. PMID: 3518163.
    Citations: 1     Fields:    Translation:Humans
  90. Matas AJ, Tellis VA, Quinn T, Soberman R, Veith FJ. Definition, diagnosis, and management of rejection in the second to sixth months posttransplant--an overview. Transplant Proc. 1986 Apr; 18(2 Suppl 1):141-50. PMID: 3515682.
    Citations:    Fields:    Translation:Humans
  91. Yoshimoto T, Soberman RJ, Lewis RA, Austen KF. Isolation and characterization of leukotriene C4 synthetase of rat basophilic leukemia cells. Proc Natl Acad Sci U S A. 1985 Dec; 82(24):8399-403. PMID: 3866231; PMCID: PMC390923.
    Citations: 14     Fields:    Translation:AnimalsCells
  92. Matas AJ, Tellis VA, Sablay L, Quinn T, Soberman R, Veith FJ. The value of needle renal allograft biopsy. III. A prospective study. Surgery. 1985 Nov; 98(5):922-6. PMID: 3904051.
    Citations: 3     Fields:    Translation:Humans
  93. Tellis VA, Matas AJ, Glichlick D, Quinn T, Soberman R, Weiss R, Veith FJ. Cyclosporine: preliminary experience in 79 patients with renal transplants. N Y State J Med. 1985 Sep; 85(9):531-4. PMID: 3903567.
    Citations:    Fields:    Translation:Humans
  94. Matas AJ, Tellis VA, Quinn T, Karwa G, Glichlick D, Soberman R, Veith F. Treatment of renal transplant rejection episodes in patients receiving prednisone and azathioprine. A cost-effective approach. Transplantation. 1985 Jul; 40(1):35-9. PMID: 3892794.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  95. Soberman RJ, Harper TW, Betteridge D, Lewis RA, Austen KF. Characterization and separation of the arachidonic acid 5-lipoxygenase and linoleic acid omega-6 lipoxygenase (arachidonic acid 15-lipoxygenase) of human polymorphonuclear leukocytes. J Biol Chem. 1985 Apr 10; 260(7):4508-15. PMID: 3920219.
    Citations: 27     Fields:    Translation:HumansCells
  96. Soberman RJ, Harper TW, Murphy RC, Austen KF. Identification and functional characterization of leukotriene B4 20-hydroxylase of human polymorphonuclear leukocytes. Proc Natl Acad Sci U S A. 1985 Apr; 82(8):2292-5. PMID: 2986111; PMCID: PMC397543.
    Citations: 11     Fields:    Translation:HumansCells
  97. Soberman RJ, Austen KF. Kinetics of the arachidonic acid 5- and 15-lipoxygenases of the human polymorphonuclear leukocyte. Adv Prostaglandin Thromboxane Leukot Res. 1985; 15:169-71. PMID: 2936086.
    Citations: 1     Fields:    Translation:HumansCells
  98. Matas AJ, Sablay L, Tellis VA, Kuemmel P, Soberman R, Veith FJ. The value of needle renal allograft biopsy. II: Reflection of acute rejection changes throughout the kidney by percutaneous biopsy. Transplantation. 1984 Jul; 38(1):92-3. PMID: 6377619.
    Citations:    Fields:    Translation:Animals
  99. Badr KF, Baylis C, Pfeffer JM, Pfeffer MA, Soberman RJ, Lewis RA, Austen KF, Corey EJ, Brenner BM. Renal and systemic hemodynamic responses to intravenous infusion of leukotriene C4 in the rat. Circ Res. 1984 May; 54(5):492-9. PMID: 6722998.
    Citations: 20     Fields:    Translation:Animals
  100. Kamholz S, Veith FJ, Mollenkopf F, Montefusco C, Nehlsen-Cannarella S, Kaleya R, Pinsker K, Tellis V, Soberman R, Sablay L, et al. Single lung transplantation in paraquat intoxication. N Y State J Med. 1984 Feb; 84(2):82-4. PMID: 6366653.
    Citations: 2     Fields:    Translation:Humans
  101. Matas AJ, Nehlsen-Cannarella S, Tellis VA, Kuemmel P, Soberman R, Veith FJ. Successful kidney transplantation with current-sera-negative/historical-sera-positive T cell crossmatch. Transplantation. 1984 Jan; 37(1):111-2. PMID: 6364479.
    Citations: 3     Fields:    Translation:HumansCells
  102. Matas AJ, Tellis VA, Veith FJ, Kuemmel P, Mollenkopf F, Karwa G, Soberman RJ. The fate of the patient returned to hemodialysis after losing a renal transplant. JAMA. 1983 Aug 26; 250(8):1053-6. PMID: 6348320.
    Citations: 1     Fields:    Translation:Humans
  103. Lewis RA, Mencia-Huerta JM, Soberman RJ, Hoover D, Marfat A, Corey EJ, Austen KF. Radioimmunoassay for leukotriene B4. Proc Natl Acad Sci U S A. 1982 Dec; 79(24):7904-8. PMID: 6296855; PMCID: PMC347458.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  104. Sniderman KW, Sprayregen S, Sos TA, Saddekni S, Hilton S, Mollenkopf F, Soberman R, Cheigh JS, Tapia L, Stubenbord W, Tellis V, Veith FJ. Percutaneous transluminal dilation in renal transplant arterial stenosis. Transplantation. 1980 Dec; 30(6):440-4. PMID: 7008292.
    Citations: 4     Fields:    Translation:Humans
  105. Soberman RJ, Karnovsky ML. Metabolism of purines in macrophages. Effect of functional state of the cells. J Exp Med. 1980 Jul 01; 152(1):241-6. PMID: 6772733; PMCID: PMC2185906.
    Citations: 3     Fields:    Translation:AnimalsCells
  106. Gliedman ML, Tellis VA, Soberman R, Rifkin H, Veith FJ. Long-term effects of pancreatic transplant function in patients with advanced juvenile-onset diabetes. Diabetes Care. 1978 Jan-Feb; 1(1):1-9. PMID: 400124.
    Citations: 10     Fields:    Translation:Humans
  107. Zarday Z, Soberman RJ. Letter: Carbamazepine in uremic neuropathy. Ann Intern Med. 1976 Mar; 84(3):296. PMID: 176912.
    Citations:    Fields:    Translation:Humans
  108. Hoffstein S, Soberman R, Goldstein I, Weissmann G. Concanavalin A induces microtubule assembly and specific granule discharge in human polymorphonuclear leukocytes. J Cell Biol. 1976 Mar; 68(3):781-7. PMID: 1025156; PMCID: PMC2109658.
    Citations: 44     Fields:    Translation:HumansCells
  109. Gliedman ML, Tellis V, Soberman R, Rifkin H, Freed SZ, Veith FJ. The clinical use of steroids in pancreatic transplantation. Transplant Proc. 1975 Mar; 7(1):93-8. PMID: 1091051.
    Citations: 5     Fields:    Translation:Humans
  110. Gliedman ML, Natale DL, Rifkin H, Soberman R, Freed S, Tellis V, Veith FJ. Clinical segmental pancreatic transplantation with ureter-to-pancreatic duct anastomosis for exocrine drainage. Bull Soc Int Chir. 1975; 34(1):15-20. PMID: 770015.
    Citations:    Fields:    Translation:HumansAnimals
  111. Zarday Z, Deery A, Tellis I, Soberman R, Foldes FF. Plasma and red cell cholinesterase activity in uremic patterns (effects of hemodialysis and renal transplantation). J Med. 1975; 6(5-6):337-49. PMID: 768397.
    Citations:    Fields:    Translation:HumansCells
  112. Gliedman ML, Tellis V, Soberman R, Rifkin H, Freed SZ, Veith FJ. Pancreatic transplantation in New York. Kidney Int Suppl. 1974 Oct; (1):164-8. PMID: 4619132.
    Citations: 1     Fields:    Translation:HumansAnimals
  113. Gliedman ML, Gold M, Whittaker J, Rifkin H, Soberman R, Freed S, Tellis V, Veith FJ. Clinical segmental pancreatic transplantation with ureter-pancreatic duct anastomosis for exocrine drainage. Surgery. 1973 Aug; 74(2):171-80. PMID: 4577803.
    Citations: 20     Fields:    Translation:Humans
  114. Whittaker JR, Veith FJ, Soberman R, Lalezari P, Tellis I, Freed SZ, Gliedman ML. The fate of the renal transplant with delayed function. Surg Gynecol Obstet. 1973 Jun; 136(6):919-22. PMID: 4574139.
    Citations: 1     Fields:    Translation:Humans
  115. Zarday Z, Benjamin JJ, Koerner SK, Veith FJ, Gliedman ML, Soberman R. Effects of hemodialysis and renal transplantation on pulmonary function. Chest. 1973 Apr; 63(4):532-5. PMID: 4571977.
    Citations: 2     Fields:    Translation:Humans
  116. Gliedman ML, Gold M, Whittaker J, Rifkin H, Soberman R, Freed S, Tellis V, Veith FJ. Pancreatic duct to ureter anastomosis for exocrine drainage in pancreatic transplantation. Am J Surg. 1973 Feb; 125(2):245-52. PMID: 4569367.
    Citations: 8     Fields:    Translation:HumansAnimals
  117. Zarday Z, Veith FJ, Gliedman ML, Soberman R. Irreversible liver damage after azathioprine. JAMA. 1972 Nov 06; 222(6):690-1. PMID: 4562099.
    Citations: 13     Fields:    Translation:Humans
  118. Tellis VA, Veith FJ, Soberman RJ, Freed SZ, Gliedman ML. Internal arteriovenous fistula for hemodialysis. Surg Gynecol Obstet. 1971 May; 132(5):866-70. PMID: 4929209.
    Citations: 4     Fields:    Translation:Humans
  119. Hays RM, Franki N, Soberman R. Activation energy for water diffusion across the toad bladder: evidence against the pore enlargement hypothesis. J Clin Invest. 1971 May; 50(5):1016-8. PMID: 5552404; PMCID: PMC292023.
    Citations: 20     Fields:    Translation:AnimalsCells
  120. Freed SZ, Veith FJ, Soberman R, Gliedman M. Simultaneous bilateral posterior nephrectomy in transplant recipients. Surgery. 1970 Sep; 68(3):468-70. PMID: 4918424.
    Citations:    Fields:    Translation:Humans
  121. Tellis V, Veith FJ, Attai-Lari A, Soberman R, Gliedman ML. Internal arteriovenous fistulae in a hemodialysis-transplant program. Trans Am Soc Artif Intern Organs. 1969; 15:293-7. PMID: 4978199.
    Citations:    Fields:    Translation:Humans
  122. FARBER SJ, SOBERMAN RJ. Total body water and total exchangeable sodium in edematous states due to cardiac, renal or hepatic disease. J Clin Invest. 1956 Jul; 35(7):779-91. PMID: 13332061; PMCID: PMC441647.
    Citations: 12     Fields:    Translation:Humans
  123. SOBERMAN RJ, KEATING RP, MAXWELL RD. Effect of acute whole body x-irradiation upon water and electrolyte balance. Am J Physiol. 1951 Feb; 164(2):450-6. PMID: 14810951.
    Citations: 2     Fields:    Translation:Humans
  124. SOBERMAN RJ. Use of antipyrine in measurement of total body water in animals. Proc Soc Exp Biol Med. 1950 Aug; 74(4):789-92. PMID: 14781184.
    Citations: 3     Fields:    Translation:Animals
  125. SOBERMAN RJ, KREVANS JR, KEATING RP. Use of radioactive phosphorus to determine volume of blood replaced in replacement transfusion. Proc Soc Exp Biol Med. 1950 Jan; 73(1):87-9. PMID: 15402530.
    Citations:    Fields:    
  126. SOBERMAN RJ. A comparison of total body water as determined by antipyrine and desiccation in rabbits. Proc Soc Exp Biol Med. 1949 Jun; 71(2):172. PMID: 18146685.
    Citations:    Fields:    Translation:AnimalsCells
  127. SOBERMAN R, BRODIE BB, et al. The use of antipyrine in the measurement of total body water in man. J Biol Chem. 1949 May; 179(1):31-42. PMID: 18119217.
    Citations: 36     Fields:    
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