Harvard Catalyst Profiles

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Hadi Shafiee, Ph.D.

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Biography
2015 - 2016
BWH Bright Futures Prize
2013 - 2015
Ruth L. Kirschstein National Research Service Award (NRSA)
2013 - 2013
MIT Media Lab, Best User Experience for HIV treatment monitoring smart phone application
2010 - 2010
Paul Torgersrsen Research Excellence Award
2010 - 2010
Liviu Librescu Fellowship

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R44HD099040 (SUBRAMANIAN, KUMAR) May 7, 2020 - Mar 31, 2020
    NIH/NICHD
    Low cost, automated smartphone based assay for semen analysis
    Role: Co-Principal Investigator
  2. R61AI140489 (SHAFIEE, HADI) Aug 9, 2019 - Jul 31, 2022
    NIH/NIAID
    A mobile health diagnostic device for HIV self-testing
    Role: Principal Investigator
  3. R01AI138800 (SHAFIEE, HADI) Dec 1, 2018 - Nov 30, 2023
    NIH/NIAID
    Microchip for HBV testing using HIV-infected blood samples
    Role: Principal Investigator
  4. R21HD092828 (SHAFIEE, HADI) Aug 11, 2017 - Jul 31, 2019
    NIH/NICHD
    A home-based, rapid, sensitive semen analyzer
    Role: Principal Investigator
  5. R01ES028712 (HART, JAIME ELIZABETH) Jan 1, 2017 - Dec 31, 2022
    NIH
    The effects of environmental exposures on semen quality and the sperm epigenome
    Role: Co-Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bormann CL, Thirumalaraju P, Kanakasabapathy MK, Kandula H, Souter I, Dimitriadis I, Gupta R, Pooniwala R, Shafiee H. Consistency and objectivity of automated embryo assessments using deep neural networks. Fertil Steril. 2020 Apr; 113(4):781-787.e1. PMID: 32228880.
    Citations:    
  2. Kanakasabapathy MK, Thirumalaraju P, Bormann CL, Kandula H, Dimitriadis I, Souter I, Yogesh V, Kota Sai Pavan S, Yarravarapu D, Gupta R, Pooniwala R, Shafiee H. Development and evaluation of inexpensive automated deep learning-based imaging systems for embryology. Lab Chip. 2019 12 21; 19(24):4139-4145. PMID: 31755505.
    Citations:    
  3. Dimitriadis I, L Bormann C, Kanakasabapathy MK, Thirumalaraju P, Kandula H, Yogesh V, Gudipati N, Natarajan V, C Petrozza J, Shafiee H. Automated smartphone-based system for measuring sperm viability, DNA fragmentation, and hyaluronic binding assay score. PLoS One. 2019; 14(3):e0212562. PMID: 30865652.
    Citations:    
  4. Potluri V, Kathiresan PS, Kandula H, Thirumalaraju P, Kanakasabapathy MK, Kota Sai Pavan S, Yarravarapu D, Soundararajan A, Baskar K, Gupta R, Gudipati N, C Petrozza J, Shafiee H. An inexpensive smartphone-based device for point-of-care ovulation testing. Lab Chip. 2018 12 18; 19(1):59-67. PMID: 30534677.
    Citations:    Fields:    
  5. Draz MS, Kochehbyoki KM, Vasan A, Battalapalli D, Sreeram A, Kanakasabapathy MK, Kallakuri S, Tsibris A, Kuritzkes DR, Shafiee H. DNA engineered micromotors powered by metal nanoparticles for motion based cellphone diagnostics. Nat Commun. 2018 10 16; 9(1):4282. PMID: 30327456.
    Citations:    Fields:    Translation:HumansCells
  6. Draz MS, Venkataramani M, Lakshminarayanan H, Saygili E, Moazeni M, Vasan A, Li Y, Sun X, Hua S, Yu XG, Shafiee H. Nanoparticle-enhanced electrical detection of Zika virus on paper microchips. Nanoscale. 2018 Jul 05; 10(25):11841-11849. PMID: 29881853.
    Citations:    Fields:    Translation:HumansCells
  7. Draz MS, Lakshminaraasimulu NK, Krishnakumar S, Battalapalli D, Vasan A, Kanakasabapathy MK, Sreeram A, Kallakuri S, Thirumalaraju P, Li Y, Hua S, Yu XG, Kuritzkes DR, Shafiee H. Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone. ACS Nano. 2018 06 26; 12(6):5709-5718. PMID: 29767504.
    Citations:    Fields:    
  8. Draz MS, Moazeni M, Venkataramani M, Lakshminarayanan H, Saygili E, Lakshminaraasimulu NK, Kochehbyoki KM, Kanakasabapathy MK, Shabahang S, Vasan A, Bijarchi MA, Memic A, Shafiee H. Hybrid Paper-Plastic Microchip for Flexible and High-Performance Point-of-Care Diagnostics. Adv Funct Mater. 2018 Jun 27; 28(26). PMID: 30416415.
    Citations:    
  9. Draz MS, Shafiee H. Applications of gold nanoparticles in virus detection. Theranostics. 2018; 8(7):1985-2017. PMID: 29556369.
    Citations: 2     Fields:    
  10. Kanakasabapathy MK, Pandya HJ, Draz MS, Chug MK, Sadasivam M, Kumar S, Etemad B, Yogesh V, Safavieh M, Asghar W, Li JZ, Tsibris AM, Kuritzkes DR, Shafiee H. Rapid, label-free CD4 testing using a smartphone compatible device. Lab Chip. 2017 08 22; 17(17):2910-2919. PMID: 28702612.
    Citations: 3     Fields:    Translation:Humans
  11. Yucha RW, Hobbs KS, Hanhauser E, Hogan LE, Nieves W, Ozen MO, Inci F, York V, Gibson EA, Thanh C, Shafiee H, El Assal R, Kiselinova M, Robles YP, Bae H, Leadabrand KS, Wang S, Deeks SG, Kuritzkes DR, Demirci U, Henrich TJ. High-throughput Characterization of HIV-1 Reservoir Reactivation Using a Single-Cell-in-Droplet PCR Assay. EBioMedicine. 2017 Jun; 20:217-229. PMID: 28529033.
    Citations: 4     Fields:    Translation:HumansCells
  12. Coarsey CT, Esiobu N, Narayanan R, Pavlovic M, Shafiee H, Asghar W. Strategies in Ebola virus disease (EVD) diagnostics at the point of care. Crit Rev Microbiol. 2017 Nov; 43(6):779-798. PMID: 28440096.
    Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
  13. Safavieh M, Pandya HJ, Venkataraman M, Thirumalaraju P, Kanakasabapathy MK, Singh A, Prabhakar D, Chug MK, Shafiee H. Rapid Real-Time Antimicrobial Susceptibility Testing with Electrical Sensing on Plastic Microchips with Printed Electrodes. ACS Appl Mater Interfaces. 2017 Apr 12; 9(14):12832-12840. PMID: 28291334.
    Citations: 3     Fields:    
  14. Pandya HJ, Dhingra K, Prabhakar D, Chandrasekar V, Natarajan SK, Vasan AS, Kulkarni A, Shafiee H. A microfluidic platform for drug screening in a 3D cancer microenvironment. Biosens Bioelectron. 2017 Aug 15; 94:632-642. PMID: 28371753.
    Citations:    Fields:    Translation:HumansAnimals
  15. Kanakasabapathy MK, Sadasivam M, Singh A, Preston C, Thirumalaraju P, Venkataraman M, Bormann CL, Draz MS, Petrozza JC, Shafiee H. An automated smartphone-based diagnostic assay for point-of-care semen analysis. Sci Transl Med. 2017 03 22; 9(382). PMID: 28330865.
    Citations: 5     Fields:    Translation:Humans
  16. Safavieh M, Kaul V, Khetani S, Singh A, Dhingra K, Kanakasabapathy MK, Draz MS, Memic A, Kuritzkes DR, Shafiee H. Paper microchip with a graphene-modified silver nano-composite electrode for electrical sensing of microbial pathogens. Nanoscale. 2017 Feb 02; 9(5):1852-1861. PMID: 27845796.
    Citations: 4     Fields:    Translation:Cells
  17. Gholizadeh S, Shehata Draz M, Zarghooni M, Sanati-Nezhad A, Ghavami S, Shafiee H, Akbari M. Microfluidic approaches for isolation, detection, and characterization of extracellular vesicles: Current status and future directions. Biosens Bioelectron. 2017 May 15; 91:588-605. PMID: 28088752.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  18. Draz MS, Wang YJ, Chen FF, Xu Y, Shafiee H. Electrically Oscillating Plasmonic Nanoparticles for Enhanced DNA Vaccination against Hepatitis C Virus. Adv Funct Mater. 2017 Feb 03; 27(5). PMID: 29180949.
    Citations: 2     
  19. Pandya HJ, Kanakasabapathy MK, Verma S, Chug MK, Memic A, Gadjeva M, Shafiee H. Label-free electrical sensing of bacteria in eye wash samples: A step towards point-of-care detection of pathogens in patients with infectious keratitis. Biosens Bioelectron. 2017 May 15; 91:32-39. PMID: 27987408.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  20. Asghar W, Shafiee H, Velasco V, Sah VR, Guo S, El Assal R, Inci F, Rajagopalan A, Jahangir M, Anchan RM, Mutter GL, Ozkan M, Ozkan CS, Demirci U. Toxicology Study of Single-walled Carbon Nanotubes and Reduced Graphene Oxide in Human Sperm. Sci Rep. 2016 08 19; 6:30270. PMID: 27538480.
    Citations: 1     Fields:    Translation:HumansCells
  21. Safavieh M, Coarsey C, Esiobu N, Memic A, Vyas JM, Shafiee H, Asghar W. Advances in Candida detection platforms for clinical and point-of-care applications. Crit Rev Biotechnol. 2017 Jun; 37(4):441-458. PMID: 27093473.
    Citations: 3     Fields:    Translation:HumansAnimals
  22. Asghar W, Yuksekkaya M, Shafiee H, Zhang M, Ozen MO, Inci F, Kocakulak M, Demirci U. Engineering long shelf life multi-layer biologically active surfaces on microfluidic devices for point of care applications. Sci Rep. 2016 Feb 17; 6:21163. PMID: 26883474.
    Citations: 6     Fields:    Translation:Humans
  23. Habibi N, Kamaly N, Memic A, Shafiee H. Self-assembled peptide-based nanostructures: Smart nanomaterials toward targeted drug delivery. Nano Today. 2016 Feb; 11(1):41-60. PMID: 27103939.
    Citations: 11     
  24. Safavieh M, Khetani S, Juillard F, Kaul V, Kanakasabapathy MK, Kaye KM, Shafiee H. Electrical response of a B lymphoma cell line latently infected with Kaposi's sarcoma herpesvirus. Biosens Bioelectron. 2016 Jun 15; 80:230-236. PMID: 26851580.
    Citations:    Fields:    Translation:HumansCells
  25. Safavieh M, Kanakasabapathy MK, Tarlan F, Ahmed MU, Zourob M, Asghar W, Shafiee H. Emerging Loop-Mediated Isothermal Amplification-Based Microchip and Microdevice Technologies for Nucleic Acid Detection. ACS Biomater Sci Eng. 2016 Mar 14; 2(3):278-294. PMID: 28503658.
    Citations: 7     
  26. Asghar W, El Assal R, Shafiee H, Pitteri S, Paulmurugan R, Demirci U. Engineering cancer microenvironments for in vitro 3-D tumor models. Mater Today (Kidlington). 2015 Dec; 18(10):539-553. PMID: 28458612.
    Citations: 14     
  27. Shafiee H, Kanakasabapathy MK, Juillard F, Keser M, Sadasivam M, Yuksekkaya M, Hanhauser E, Henrich TJ, Kuritzkes DR, Kaye KM, Demirci U. Printed Flexible Plastic Microchip for Viral Load Measurement through Quantitative Detection of Viruses in Plasma and Saliva. Sci Rep. 2015 Jun 05; 5:9919. PMID: 26046668.
    Citations: 5     Fields:    Translation:HumansCells
  28. Tokel O, Yildiz UH, Inci F, Durmus NG, Ekiz OO, Turker B, Cetin C, Rao S, Sridhar K, Natarajan N, Shafiee H, Dana A, Demirci U. Portable microfluidic integrated plasmonic platform for pathogen detection. Sci Rep. 2015 Mar 24; 5:9152. PMID: 25801042.
    Citations: 12     Fields:    Translation:HumansCells
  29. Shafiee H, Asghar W, Inci F, Yuksekkaya M, Jahangir M, Zhang MH, Durmus NG, Gurkan UA, Kuritzkes DR, Demirci U. Paper and flexible substrates as materials for biosensing platforms to detect multiple biotargets. Sci Rep. 2015 Mar 06; 5:8719. PMID: 25743880.
    Citations: 17     Fields:    Translation:HumansCells
  30. Shafiee H, Wang S, Inci F, Toy M, Henrich TJ, Kuritzkes DR, Demirci U. Emerging technologies for point-of-care management of HIV infection. Annu Rev Med. 2015; 66:387-405. PMID: 25423597.
    Citations: 14     Fields:    Translation:Humans
  31. El Assal R, Guven S, Gurkan UA, Gozen I, Shafiee H, Dalbeyler S, Abdalla N, Thomas G, Fuld W, Illigens BM, Estanislau J, Khoory J, Kaufman R, Zylberberg C, Lindeman N, Wen Q, Ghiran I, Demirci U. Bio-inspired cryo-ink preserves red blood cell phenotype and function during nanoliter vitrification. Adv Mater. 2014 Sep 03; 26(33):5815-22. PMID: 25047246.
    Citations: 5     Fields:    Translation:HumansCells
  32. Asghar W, El Assal R, Shafiee H, Anchan RM, Demirci U. Preserving human cells for regenerative, reproductive, and transfusion medicine. Biotechnol J. 2014 Jul; 9(7):895-903. PMID: 24995723.
    Citations: 7     Fields:    Translation:HumansCells
  33. Asghar W, Velasco V, Kingsley JL, Shoukat MS, Shafiee H, Anchan RM, Mutter GL, Tüzel E, Demirci U. Selection of functional human sperm with higher DNA integrity and fewer reactive oxygen species. Adv Healthc Mater. 2014 Oct; 3(10):1671-9. PMID: 24753434.
    Citations: 12     Fields:    Translation:HumansCells
  34. Hadi Shafiee, Erich A Lidstone, Muntasir Jahangir, Fatih Inci, Emily Hanhauser, Timothy J Henrich, Daniel R Kuritzkes, Brian T Cunningham, Utkan Demirci. Nanostructured Optical Photonic Crystal Biosensor for HIV Viral Load Measurement. Nature Scientific Reports. 2014; 4. View Publication.
  35. Shafiee H, Lidstone EA, Jahangir M, Inci F, Hanhauser E, Henrich TJ, Kuritzkes DR, Cunningham BT, Demirci U. Nanostructured optical photonic crystal biosensor for HIV viral load measurement. Sci Rep. 2014 Feb 28; 4:4116. PMID: 24576941.
    Citations: 16     Fields:    Translation:HumansCells
  36. Shafiee H, Jahangir M, Inci F, Wang S, Willenbrecht RB, Giguel FF, Tsibris AM, Kuritzkes DR, Demirci U. Acute on-chip HIV detection through label-free electrical sensing of viral nano-lysate. Small. 2013 Aug 12; 9(15):2553-63, 2478. PMID: 23447456.
    Citations: 19     Fields:    Translation:HumansCells
  37. Shafiee H, M. Jahangir, F. Inci, S. Wang, F. F. Giguel, D. R. Kuritzkes, and U. Demirci. Acute HIV Detection by Viral Lysate Impedance Spectroscopy on a Microchip. 2013.
  38. Shafiee H, M. Jahangir, F. Inci, S. Wang, R. B.B. Willenbrecht, F. F. Giguel, A.M.N. Tsibris, D. R. Kuritzkes, and U. Demirci. Acute HIV Detection through Label-free Electrical Sensing of Viral Nano-lysate on-Chip. Small Journal. 2013. View Publication.
  39. Shafiee H, M. Jahangir, F. Inci, S. Wang, F. F. Giguel, D. R. Kuritzkes, and U. Demirci. Towards Point-of-Care HIV-1 Detection through Electrical Sensing-on-a-Chip. 2012.
  40. Shafiee H, M. Jahangir, F. Inci, S. Wang, F. F. Giguel, D. R. Kuritzkes, and U. Demirci. A Microchip for HIV-1 Detection at the Point-of-Care. 2012.
  41. Salmanzadeh A, Sano MB, Shafiee H, Stremler MA, Davalos RV. Isolation of rare cancer cells from blood cells using dielectrophoresis. Conf Proc IEEE Eng Med Biol Soc. 2012; 2012:590-3. PMID: 23365961.
    Citations: 6     Fields:    Translation:HumansCells
  42. Salmanzadeh A, Romero L, Shafiee H, Gallo-Villanueva RC, Stremler MA, Cramer SD, Davalos RV. Isolation of prostate tumor initiating cells (TICs) through their dielectrophoretic signature. Lab Chip. 2012 Jan 07; 12(1):182-9. PMID: 22068834.
    Citations: 30     Fields:    Translation:HumansCells
  43. Salmanzadeh A, Shafiee H, Davalos RV, Stremler MA. Microfluidic mixing using contactless dielectrophoresis. Electrophoresis. 2011 Sep; 32(18):2569-78. PMID: 21922498.
    Citations: 4     Fields:    
  44. Welsh JD, Charonko JJ, Salmanzadeh A, Drahos KE, Shafiee H, Stremler MA, Davalos RV, Capelluto DG, Vlachos PP, Finkielstein CV. Disabled-2 modulates homotypic and heterotypic platelet interactions by binding to sulfatides. Br J Haematol. 2011 Jul; 154(1):122-33. PMID: 21539534.
    Citations: 4     Fields:    Translation:HumansCells
  45. Shafiee H, Sano MB, Henslee EA, Caldwell JL, Davalos RV. Selective isolation of live/dead cells using contactless dielectrophoresis (cDEP). Lab Chip. 2010 Feb 21; 10(4):438-45. PMID: 20126683.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  46. Shafiee H, JL Caldwell, RV Davalos . A Microfluidic System for Biological Particle Enrichment Utilizing Contactless Dielectrophoresis (cDEP). Journal of the Association for Laboratory Automation (JALA). 2010. View Publication.
  47. Shafiee H, Garcia PA, Davalos RV. A preliminary study to delineate irreversible electroporation from thermal damage using the arrhenius equation. J Biomech Eng. 2009 Jul; 131(7):074509. PMID: 19640145.
    Citations: 11     Fields:    Translation:HumansCells
  48. Shafiee H, Caldwell JL, Sano MB, Davalos RV. Contactless dielectrophoresis: a new technique for cell manipulation. Biomed Microdevices. 2009 Oct; 11(5):997-1006. PMID: 19415498.
    Citations: 29     Fields:    Translation:HumansCells
  49. 10. Shafiee H, MH Naei, and MR Eslami. Mechanical In-Plane and Out-of-Plane Buckling of Arches made of FGM. International Journal of Mechanical Science. 2006; 48(8):907-915.
  50. Rastgoo A, H Shafiee, and A Allahverdizadeh. Instability of Curved Beams Made of FGM Under thermal Loading. International Journal of Mechanics and Material in Design. 2006; 2:117-128.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.