Harvard Catalyst Profiles

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Hadi Shafiee, Ph.D.

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Biography
awards and honors
2015 - 2016
BWH Bright Futures Prize
2013 - 2015
Ruth L. Kirschstein National Research Service Award (NRSA)
2013 - 2013
MIT Media Lab, Best User Experience for HIV treatment monitoring smart phone application
2010 - 2010
Paul Torgersrsen Research Excellence Award
2010 - 2010
Liviu Librescu Fellowship

Overview

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
Most Recent  |  List All
  1. R61AI140489 (SHAFIEE, HADI) Aug 9, 2019 - Jul 31, 2022
    NIH
    A mobile health diagnostic device for HIV self-testing
    Role: Principal Investigator
  2. R44HD099040 (SUBRAMANIAN, KUMAR) Apr 1, 2019 - Apr 30, 2022
    NIH
    Low cost, automated smartphone based assay for semen analysis
    Role: Co-Principal Investigator
  3. R01AI138800 (SHAFIEE, HADI) Dec 1, 2018 - Nov 30, 2023
    NIH
    Microchip for HBV testing using HIV-infected blood samples
    Role: Principal Investigator
  4. R21HD092828 (SHAFIEE, HADI) Aug 11, 2017 - Jul 31, 2020
    NIH
    A home-based, rapid, sensitive semen analyzer
    Role: Principal Investigator
  5. R01ES028712 (HART, JAIME ELIZABETH) Jan 1, 2017 - Dec 31, 2022
    NIH
    The effects of environmental exposures on semen quality and the sperm epigenome
    Role: Co-Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Jiang VS, Kandula H, Thirumalaraju P, Kanakasabapathy MK, Cherouveim P, Souter I, Dimitriadis I, Bormann CL, Shafiee H. The use of voting ensembles to improve the accuracy of deep neural networks as a non-invasive method to predict embryo ploidy status. J Assist Reprod Genet. 2023 Feb; 40(2):301-308. PMID: 36640251; PMCID: PMC9935776.
    Citations:    Fields:    Translation:Humans
  2. Jiang VS, Kartik D, Thirumalaraju P, Kandula H, Kanakasabapathy MK, Souter I, Dimitriadis I, Bormann CL, Shafiee H. Advancements in the future of automating micromanipulation techniques in the IVF laboratory using deep convolutional neural networks. J Assist Reprod Genet. 2023 Feb; 40(2):251-257. PMID: 36586006; PMCID: PMC9935764.
    Citations:    Fields:    Translation:Animals
  3. Chen H, Kim S, Hardie JM, Thirumalaraju P, Gharpure S, Rostamian S, Udayakumar S, Lei Q, Cho G, Kanakasabapathy MK, Shafiee H. Deep learning-assisted sensitive detection of fentanyl using a bubbling-microchip. Lab Chip. 2022 11 22; 22(23):4531-4540. PMID: 36331061; PMCID: PMC9710303.
    Citations:    Fields:    Translation:Humans
  4. Cherouveim P, Jiang VS, Kanakasabapathy MK, Thirumalaraju P, Souter I, Dimitriadis I, Bormann CL, Shafiee H. Quality assurance (QA) for monitoring the performance of assisted reproductive technology (ART) staff using artificial intelligence (AI). J Assist Reprod Genet. 2023 Feb; 40(2):241-249. PMID: 36374394; PMCID: PMC9935795.
    Citations: 1     Fields:    Translation:Humans
  5. Suárez-Trujillo A, Kandula H, Kumar J, Devi A, Shirley L, Thirumalaraju P, Kanakasabapathy MK, Shafiee H, Hart L. Validation of a smartphone-based device to measure concentration, motility, and morphology in swine ejaculates. Transl Anim Sci. 2022 Oct; 6(4):txac119. PMID: 36263416; PMCID: PMC9558898.
    Citations:    
  6. Hammer KC, Jiang VS, Kanakasabapathy MK, Thirumalaraju P, Kandula H, Dimitriadis I, Souter I, Bormann CL, Shafiee H. Using artificial intelligence to avoid human error in identifying embryos: a retrospective cohort study. J Assist Reprod Genet. 2022 Oct; 39(10):2343-2348. PMID: 35962845; PMCID: PMC9596636.
    Citations: 1     Fields:    Translation:Humans
  7. Fitz VW, Kanakasabapathy MK, Thirumalaraju P, Kandula H, Ramirez LB, Boehnlein L, Swain JE, Curchoe CL, James K, Dimitriadis I, Souter I, Bormann CL, Shafiee H. Should there be an "AI" in TEAM? Embryologists selection of high implantation potential embryos improves with the aid of an artificial intelligence algorithm. J Assist Reprod Genet. 2021 Oct; 38(10):2663-2670. PMID: 34535847; PMCID: PMC8581077.
    Citations: 4     Fields:    Translation:Humans
  8. Silva FSR, Erdogmus E, Shokr A, Kandula H, Thirumalaraju P, Kanakasabapathy MK, Hardie JM, Pacheco LGC, Li JZ, Kuritzkes DR, Shafiee H. SARS-CoV-2 RNA Detection by a Cellphone-Based Amplification-Free System with CRISPR/CAS-Dependent Enzymatic (CASCADE) Assay. Adv Mater Technol. 2021 Dec; 6(12):2100602. PMID: 34514084; PMCID: PMC8420437.
    Citations: 15     
  9. Bormann CL, Curchoe CL, Thirumalaraju P, Kanakasabapathy MK, Gupta R, Pooniwala R, Kandula H, Souter I, Dimitriadis I, Shafiee H. Correction to: Deep learning early warning system for embryo culture conditions and embryologist performance in the ART laboratory. J Assist Reprod Genet. 2021 Jul; 38(7):1893. PMID: 33990900.
    Citations:    Fields:    
  10. Kanakasabapathy MK, Thirumalaraju P, Kandula H, Doshi F, Sivakumar AD, Kartik D, Gupta R, Pooniwala R, Branda JA, Tsibris AM, Kuritzkes DR, Petrozza JC, Bormann CL, Shafiee H. Adaptive adversarial neural networks for the analysis of lossy and domain-shifted datasets of medical images. Nat Biomed Eng. 2021 06; 5(6):571-585. PMID: 34112997; PMCID: PMC8943917.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  11. Bormann CL, Curchoe CL, Thirumalaraju P, Kanakasabapathy MK, Gupta R, Pooniwala R, Kandula H, Souter I, Dimitriadis I, Shafiee H. Deep learning early warning system for embryo culture conditions and embryologist performance in the ART laboratory. J Assist Reprod Genet. 2021 Jul; 38(7):1641-1646. PMID: 33904010; PMCID: PMC8324654.
    Citations: 5     Fields:    Translation:Humans
  12. Thirumalaraju P, Kanakasabapathy MK, Bormann CL, Gupta R, Pooniwala R, Kandula H, Souter I, Dimitriadis I, Shafiee H. Evaluation of deep convolutional neural networks in classifying human embryo images based on their morphological quality. Heliyon. 2021 Feb; 7(2):e06298. PMID: 33665450.
    Citations: 5     
  13. Tavakoli F, Ghasemikhah R, Shafiee H. Customizing the Protoscolicidal Activity by a Drug Delivery System: Application of Guar Gum in Electrospun Nanofibers. Iran J Parasitol. 2021 Jan-Mar; 16(1):136-145. PMID: 33786055; PMCID: PMC7988667.
    Citations:    
  14. Draz MS, Vasan A, Muthupandian A, Kanakasabapathy MK, Thirumalaraju P, Sreeram A, Krishnakumar S, Yogesh V, Lin W, Yu XG, Chung RT, Shafiee H. Virus detection using nanoparticles and deep neural network-enabled smartphone system. Sci Adv. 2020 12; 6(51). PMID: 33328239; PMCID: PMC7744080.
    Citations: 7     Fields:    
  15. Shokr A, Pacheco LGC, Thirumalaraju P, Kanakasabapathy MK, Gandhi J, Kartik D, Silva FSR, Erdogmus E, Kandula H, Luo S, Yu XG, Chung RT, Li JZ, Kuritzkes DR, Shafiee H. Mobile Health (mHealth) Viral Diagnostics Enabled with Adaptive Adversarial Learning. ACS Nano. 2021 01 26; 15(1):665-673. PMID: 33226787; PMCID: PMC8299938.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  16. Curchoe CL, Malmsten J, Bormann C, Shafiee H, Flores-Saiffe Farias A, Mendizabal G, Chavez-Badiola A, Sigaras A, Alshubbar H, Chambost J, Jacques C, Pena CA, Drakeley A, Freour T, Hajirasouliha I, Hickman CFL, Elemento O, Zaninovic N, Rosenwaks Z. Predictive modeling in reproductive medicine: Where will the future of artificial intelligence research take us? Fertil Steril. 2020 11; 114(5):934-940. PMID: 33160516.
    Citations: 7     Fields:    Translation:HumansAnimals
  17. Bormann CL, Kanakasabapathy MK, Thirumalaraju P, Gupta R, Pooniwala R, Kandula H, Hariton E, Souter I, Dimitriadis I, Ramirez LB, Curchoe CL, Swain J, Boehnlein LM, Shafiee H. Performance of a deep learning based neural network in the selection of human blastocysts for implantation. Elife. 2020 09 15; 9. PMID: 32930094.
    Citations: 19     Fields:    Translation:Humans
  18. Adans-Dester CP, Bamberg S, Bertacchi FP, Caulfield B, Chappie K, Demarchi D, Erb MK, Estrada J, Fabara EE, Freni M, Friedl KE, Ghaffari R, Gill G, Greenberg MS, Hoyt RW, Jovanov E, Kanzler CM, Katabi D, Kernan M, Kigin C, Lee SI, Leonhardt S, Lovell NH, Mantilla J, McCoy TH, Luo NM, Miller GA, Moore J, O'Keeffe D, Palmer J, Parisi F, Patel S, Po J, Pugliese BL, Quatieri T, Rahman T, Ramasarma N, Rogers JA, Ruiz-Esparza GU, Sapienza S, Schiurring G, Schwamm L, Shafiee H, Kelly Silacci S, Sims NM, Talkar T, Tharion WJ, Toombs JA, Uschnig C, Vergara-Diaz GP, Wacnik P, Wang MD, Welch J, Williamson L, Zafonte R, Zai A, Zhang YT, Tearney GJ, Ahmad R, Walt DR, Bonato P. Can mHealth Technology Help Mitigate the Effects of the COVID-19 Pandemic? IEEE Open J Eng Med Biol. 2020; 1:243-248. PMID: 34192282; PMCID: PMC8023427.
    Citations: 24     
  19. Bormann CL, Thirumalaraju P, Kanakasabapathy MK, Kandula H, Souter I, Dimitriadis I, Gupta R, Pooniwala R, Shafiee H. Consistency and objectivity of automated embryo assessments using deep neural networks. Fertil Steril. 2020 04; 113(4):781-787.e1. PMID: 32228880.
    Citations: 17     Fields:    Translation:Humans
  20. Kanakasabapathy MK, Thirumalaraju P, Bormann CL, Kandula H, Dimitriadis I, Souter I, Yogesh V, Kota Sai Pavan S, Yarravarapu D, Gupta R, Pooniwala R, Shafiee H. Development and evaluation of inexpensive automated deep learning-based imaging systems for embryology. Lab Chip. 2019 12 21; 19(24):4139-4145. PMID: 31755505.
    Citations: 11     Fields:    Translation:Humans
  21. Dimitriadis I, L Bormann C, Kanakasabapathy MK, Thirumalaraju P, Kandula H, Yogesh V, Gudipati N, Natarajan V, C Petrozza J, Shafiee H. Automated smartphone-based system for measuring sperm viability, DNA fragmentation, and hyaluronic binding assay score. PLoS One. 2019; 14(3):e0212562. PMID: 30865652.
    Citations: 4     Fields:    Translation:Humans
  22. Potluri V, Kathiresan PS, Kandula H, Thirumalaraju P, Kanakasabapathy MK, Kota Sai Pavan S, Yarravarapu D, Soundararajan A, Baskar K, Gupta R, Gudipati N, C Petrozza J, Shafiee H. An inexpensive smartphone-based device for point-of-care ovulation testing. Lab Chip. 2018 12 18; 19(1):59-67. PMID: 30534677.
    Citations: 7     Fields:    Translation:Humans
  23. Draz MS, Kochehbyoki KM, Vasan A, Battalapalli D, Sreeram A, Kanakasabapathy MK, Kallakuri S, Tsibris A, Kuritzkes DR, Shafiee H. DNA engineered micromotors powered by metal nanoparticles for motion based cellphone diagnostics. Nat Commun. 2018 10 16; 9(1):4282. PMID: 30327456.
    Citations: 18     Fields:    Translation:HumansCells
  24. Draz MS, Venkataramani M, Lakshminarayanan H, Saygili E, Moazeni M, Vasan A, Li Y, Sun X, Hua S, Yu XG, Shafiee H. Nanoparticle-enhanced electrical detection of Zika virus on paper microchips. Nanoscale. 2018 Jul 05; 10(25):11841-11849. PMID: 29881853.
    Citations: 11     Fields:    Translation:HumansCells
  25. Draz MS, Lakshminaraasimulu NK, Krishnakumar S, Battalapalli D, Vasan A, Kanakasabapathy MK, Sreeram A, Kallakuri S, Thirumalaraju P, Li Y, Hua S, Yu XG, Kuritzkes DR, Shafiee H. Motion-Based Immunological Detection of Zika Virus Using Pt-Nanomotors and a Cellphone. ACS Nano. 2018 06 26; 12(6):5709-5718. PMID: 29767504; PMCID: PMC6860978.
    Citations: 20     Fields:    Translation:HumansCells
  26. Draz MS, Moazeni M, Venkataramani M, Lakshminarayanan H, Saygili E, Lakshminaraasimulu NK, Kochehbyoki KM, Kanakasabapathy MK, Shabahang S, Vasan A, Bijarchi MA, Memic A, Shafiee H. Hybrid Paper-Plastic Microchip for Flexible and High-Performance Point-of-Care Diagnostics. Adv Funct Mater. 2018 Jun 27; 28(26). PMID: 30416415; PMCID: PMC6223320.
    Citations: 8     
  27. Draz MS, Shafiee H. Applications of gold nanoparticles in virus detection. Theranostics. 2018; 8(7):1985-2017. PMID: 29556369.
    Citations: 74     Fields:    Translation:HumansAnimalsCells
  28. Kanakasabapathy MK, Pandya HJ, Draz MS, Chug MK, Sadasivam M, Kumar S, Etemad B, Yogesh V, Safavieh M, Asghar W, Li JZ, Tsibris AM, Kuritzkes DR, Shafiee H. Rapid, label-free CD4 testing using a smartphone compatible device. Lab Chip. 2017 08 22; 17(17):2910-2919. PMID: 28702612.
    Citations: 25     Fields:    Translation:Humans
  29. Kanakasabapathy MK, Sadasivam M, Singh A, Preston C, Thirumalaraju P, Venkataraman M, Bormann CL, Draz MS, Petrozza JC, Shafiee H. An automated smartphone-based diagnostic assay for point-of-care semen analysis. Sci Transl Med. 2017 03 22; 9(382). PMID: 28330865.
    Citations: 42     Fields:    Translation:Humans
  30. Safavieh M, Kaul V, Khetani S, Singh A, Dhingra K, Kanakasabapathy MK, Draz MS, Memic A, Kuritzkes DR, Shafiee H. Paper microchip with a graphene-modified silver nano-composite electrode for electrical sensing of microbial pathogens. Nanoscale. 2017 Feb 02; 9(5):1852-1861. PMID: 27845796.
    Citations: 17     Fields:    Translation:Cells
  31. Draz MS, Wang YJ, Chen FF, Xu Y, Shafiee H. Electrically Oscillating Plasmonic Nanoparticles for Enhanced DNA Vaccination against Hepatitis C Virus. Adv Funct Mater. 2017 Feb 03; 27(5). PMID: 29180949; PMCID: PMC5701658.
    Citations: 13     
  32. Habibi N, Kamaly N, Memic A, Shafiee H. Self-assembled peptide-based nanostructures: Smart nanomaterials toward targeted drug delivery. Nano Today. 2016 Feb; 11(1):41-60. PMID: 27103939; PMCID: PMC4834907.
    Citations: 99     
  33. Safavieh M, Kanakasabapathy MK, Tarlan F, Ahmed MU, Zourob M, Asghar W, Shafiee H. Emerging Loop-Mediated Isothermal Amplification-Based Microchip and Microdevice Technologies for Nucleic Acid Detection. ACS Biomater Sci Eng. 2016 Mar 14; 2(3):278-294. PMID: 28503658; PMCID: PMC5425166.
    Citations: 45     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.