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Kathryn Gray, M.D.,Ph.D.

Title
Institution
Department
Address

Biography
University of Wisconsin-Madison, Madison, WisconsinBS05/1999Biochemistry
University of Michigan, Ann Arbor, MIMD, PhD05/2007Medicine / Immunology
Emory University, Atlanta, GAResidency06/2011Obstetrics & Gynecology
Brigham & Women's Hospital, Boston, MAFellowship06/2016Maternal-Fetal Medicine/ Clinical Genetics
2017
ACOG Mentor of the Year
2017 - 2019
BIRCWH Scholar
2017 - 2018
Obstetrics & Gynecology Foundation Fellowship

Overview

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08HL146963 (GRAY, KATHRYN JOHNSON) Apr 3, 2019 - Sep 30, 2023
    NIH
    Signatures of dysfunctional mitochondrial fatty acid oxidation that predispose to early-onset preeclampsia
    Role: Principal Investigator
  2. F32HD086948 (GRAY, KATHRYN JOHNSON) Aug 5, 2016 - Aug 4, 2018
    NIH
    Longitudinal metabolic profiling throughout gestation in the plasma and urine of women who develop early-onset preeclampsia
    Role: Principal Investigator

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gray KJ. Providing Data to Empower Pregnant Patients to Make Evidence-Based Choices. JAMA Netw Open. 2021 Apr 01; 4(4):e215359. PMID: 33890997.
    Citations:    Fields:    
  2. Guseh S, Wilkins-Haug L, Kaimal A, Dunn-Albanese L, Adams S, Carroll S, Discenza M, Dobson L, Brillinger M, Foster J, Gbur S, Green H, Herrig N, Mandigo C, Pacione M, Roberts P, Sassaman A, Steinberg K, Studwell C, Gray KJ. Utility of noninvasive genome-wide screening: a prospective cohort of obstetric patients undergoing diagnostic testing. Genet Med. 2021 Mar 29. PMID: 33782554.
    Citations:    Fields:    
  3. Gray KJ, Bordt EA, Atyeo C, Deriso E, Akinwunmi B, Young N, Medina Baez A, Shook LL, Cvrk D, James K, De Guzman R, Brigida S, Diouf K, Goldfarb I, Bebell LM, Yonker LM, Fasano A, Rabi SA, Elovitz MA, Alter G, Edlow AG. COVID-19 vaccine response in pregnant and lactating women: a cohort study. Am J Obstet Gynecol. 2021 Mar 24. PMID: 33775692.
    Citations: 2     Fields:    
  4. Bateman BT, Hernandez-Diaz S, Straub L, Zhu Y, Gray KJ, Desai RJ, Mogun H, Gautam N, Huybrechts KF. Association of first trimester prescription opioid use with congenital malformations in the offspring: population based cohort study. BMJ. 2021 02 10; 372:n102. PMID: 33568363.
    Citations: 1     Fields:    Translation:Humans
  5. Straub L, Huybrechts KF, Hernandez-Diaz S, Zhu Y, Vine S, Desai RJ, Gray KJ, Bateman BT. Chronic prescription opioid use in pregnancy in the United States. Pharmacoepidemiol Drug Saf. 2021 Apr; 30(4):504-513. PMID: 33428239.
    Citations:    Fields:    
  6. Atyeo C, Pullen KM, Bordt EA, Fischinger S, Burke J, Michell A, Slein MD, Loos C, Shook LL, Boatin AA, Yockey LJ, Pepin D, Meinsohn MC, Nguyen NMP, Chauvin M, Roberts D, Goldfarb IT, Matute JD, James KE, Yonker LM, Bebell LM, Kaimal AJ, Gray KJ, Lauffenburger D, Edlow AG, Alter G. Compromised SARS-CoV-2-specific placental antibody transfer. Cell. 2021 02 04; 184(3):628-642.e10. PMID: 33476549.
    Citations: 5     Fields:    Translation:HumansCells
  7. Edlow AG, Li JZ, Collier AY, Atyeo C, James KE, Boatin AA, Gray KJ, Bordt EA, Shook LL, Yonker LM, Fasano A, Diouf K, Croul N, Devane S, Yockey LJ, Lima R, Shui J, Matute JD, Lerou PH, Akinwunmi BO, Schmidt A, Feldman J, Hauser BM, Caradonna TM, De la Flor D, D'Avino P, Regan J, Corry H, Coxen K, Fajnzylber J, Pepin D, Seaman MS, Barouch DH, Walker BD, Yu XG, Kaimal AJ, Roberts DJ, Alter G. Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic. JAMA Netw Open. 2020 12 01; 3(12):e2030455. PMID: 33351086.
    Citations: 15     Fields:    Translation:HumansCells
  8. McElrath TF, Cantonwine DE, Gray KJ, Mirzakhani H, Doss RC, Khaja N, Khalid M, Page G, Brohman B, Zhang Z, Sarracino D, Rosenblatt KP. Late first trimester circulating microparticle proteins predict the risk of preeclampsia PMID: 33087742.
    Citations:    Fields:    Translation:HumansCells
  9. Gray KJ. Tolerance of uncertainty: a unifying theme in pregnancy care. BJOG. 2021 01; 128(2):439. PMID: 32892454.
    Citations:    Fields:    Translation:Humans
  10. Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, Wilson ML, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R. Risk of pre-eclampsia in patients with a maternal genetic predisposition to common medical conditions: a case-control study. BJOG. 2021 01; 128(1):55-65. PMID: 32741103.
    Citations: 1     Fields:    Translation:Humans
  11. Gray KJ, Wilkins-Haug L. Special issue on "Feto-Maternal Genomic Medicine": a decade of incredible advances. Hum Genet. 2020 Sep; 139(9):1119-1120. PMID: 32840692.
    Citations:    Fields:    Translation:Humans
  12. Zhu Y, Bateman BT, Gray KJ, Hernandez-Diaz S, Mogun H, Straub L, Huybrechts KF. Oral fluconazole use in the first trimester and risk of congenital malformations: population based cohort study. BMJ. 2020 May 20; 369:m1494. PMID: 32434758.
    Citations: 2     Fields:    Translation:Humans
  13. He M, Huybrechts KF, Dejene SZ, Straub L, Bartels D, Burns S, Combs DJ, Cottral J, Gray KJ, Manning-Geist BL, Mogun H, Reimers RM, Hernandez-Diaz S, Bateman BT. Validation of algorithms to identify adverse perinatal outcomes in the Medicaid Analytic Extract database. Pharmacoepidemiol Drug Saf. 2020 04; 29(4):419-426. PMID: 32124511.
    Citations: 1     Fields:    Translation:Humans
  14. Huybrechts KF, Hernandez-Diaz S, Straub L, Gray KJ, Zhu Y, Mogun H, Bateman BT. Intravenous Ondansetron in Pregnancy and Risk of Congenital Malformations. JAMA. 2020 01 28; 323(4):372-374. PMID: 31730152.
    Citations: 2     Fields:    Translation:Humans
  15. Straub L, Huybrechts KF, Bateman BT, Mogun H, Gray KJ, Holmes LB, Hernandez-Diaz S. The Impact of Technology on the Diagnosis of Congenital Malformations. Am J Epidemiol. 2019 11 01; 188(11):1892-1901. PMID: 31241162.
    Citations: 1     Fields:    Translation:Humans
  16. Gray KJ, Wilkins-Haug LE, Herrig NJ, Vora NL. Fetal phenotypes emerge as genetic technologies become robust. Prenat Diagn. 2019 08; 39(9):811-817. PMID: 31330568.
    Citations: 5     Fields:    Translation:Humans
  17. Reale SC, Gray KJ, Boyer EW, Arce DY, Farber MK. Toxic Ingestion of Acetaminophen and Acetylsalicylic Acid in a Parturient at 33 Weeks Gestation: A Case Report. A A Pract. 2019 May 01; 12(9):302-304. PMID: 30312176.
    Citations:    Fields:    Translation:Humans
  18. Naoum EE, Leffert LR, Chitilian HV, Gray KJ, Bateman BT. Acute Fatty Liver of Pregnancy: Pathophysiology, Anesthetic Implications, and Obstetrical Management. Anesthesiology. 2019 03; 130(3):446-461. PMID: 30707120.
    Citations: 7     Fields:    Translation:Humans
  19. Huybrechts KF, Hernández-Díaz S, Straub L, Gray KJ, Zhu Y, Patorno E, Desai RJ, Mogun H, Bateman BT. Association of Maternal First-Trimester Ondansetron Use With Cardiac Malformations and Oral Clefts in Offspring. JAMA. 2018 12 18; 320(23):2429-2437. PMID: 30561479.
    Citations: 16     Fields:    Translation:Humans
  20. Covarrubias AE, Lecarpentier E, Lo A, Salahuddin S, Gray KJ, Karumanchi SA, Zsengellér ZK. AP39, a Modulator of Mitochondrial Bioenergetics, Reduces Antiangiogenic Response and Oxidative Stress in Hypoxia-Exposed Trophoblasts: Relevance for Preeclampsia Pathogenesis. Am J Pathol. 2019 01; 189(1):104-114. PMID: 30315766.
    Citations: 7     Fields:    Translation:HumansCells
  21. Panchaud A, Cohen JM, Patorno E, Huybrechts KF, Desai RJ, Gray KJ, Mogun H, Hernandez-Diaz S, Bateman BT. Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study. Neurology. 2018 08 07; 91(6):e533-e542. PMID: 29980637.
    Citations:    Fields:    Translation:Humans
  22. Gray KJ, Kovacheva VP, Mirzakhani H, Bjonnes AC, Almoguera B, DeWan AT, Triche EW, Saftlas AF, Hoh J, Bodian DL, Klein E, Huddleston KC, Ingles SA, Lockwood CJ, Hakonarson H, McElrath TF, Murray JC, Wilson ML, Norwitz ER, Karumanchi SA, Bateman BT, Keating BJ, Saxena R. Gene-Centric Analysis of Preeclampsia Identifies Maternal Association at PLEKHG1. Hypertension. 2018 08; 72(2):408-416. PMID: 29967039.
    Citations: 9     Fields:    Translation:Humans
  23. Gray KJ, Wilkins-Haug LE. Have we done our last amniocentesis? Updates on cell-free DNA for Down syndrome screening. Pediatr Radiol. 2018 04; 48(4):461-470. PMID: 29550862.
    Citations: 3     Fields:    Translation:Humans
  24. Cohen JM, Hernández-Díaz S, Bateman BT, Park Y, Desai RJ, Gray KJ, Patorno E, Mogun H, Huybrechts KF. Placental Complications Associated With Psychostimulant Use in Pregnancy. Obstet Gynecol. 2017 12; 130(6):1192-1201. PMID: 29112657.
    Citations: 7     Fields:    Translation:Humans
  25. Gray KJ, Saxena R, Karumanchi SA. Genetic predisposition to preeclampsia is conferred by fetal DNA variants near FLT1, a gene involved in the regulation of angiogenesis. Am J Obstet Gynecol. 2018 02; 218(2):211-218. PMID: 29138037.
    Citations: 10     Fields:    Translation:Humans
  26. Gansner JM, Achebe MM, Gray KJ, Yefidoff-Freedman R, Labovitis E, Parnes A, Connors JM, Connell NT, Discenza MN, Handin RI, Berliner N, Shimamura A, Ginsburg ES, Smith NA. Pregnancy outcomes in inherited bone marrow failure syndromes. Blood. 2017 10 05; 130(14):1671-1674. PMID: 28798157.
    Citations: 2     Fields:    Translation:Humans
  27. Kelly RS, Giorgio RT, Chawes BL, Palacios NI, Gray KJ, Mirzakhani H, Wu A, Blighe K, Weiss ST, Lasky-Su J. Applications of Metabolomics in the Study and Management of Preeclampsia; A Review of the Literature. Metabolomics. 2017 07; 13(7). PMID: 30473646.
    Citations: 10     Fields:    
  28. Kelly RS, Croteau-Chonka DC, Dahlin A, Mirzakhani H, Wu AC, Wan ES, McGeachie MJ, Qiu W, Sordillo JE, Al-Garawi A, Gray KJ, McElrath TF, Carey VJ, Clish CB, Litonjua AA, Weiss ST, Lasky-Su JA. Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia. Metabolomics. 2017 Jan; 13(1). PMID: 28596717.
    Citations: 15     Fields:    
  29. Lamont RE, Tan WH, Innes AM, Parboosingh JS, Schneidman-Duhovny D, Rajkovic A, Pappas J, Altschwager P, DeWard S, Fulton A, Gray KJ, Krall M, Mehta L, Rodan LH, Saller DN, Steele D, Stein D, Yatsenko SA, Bernier FP, Slavotinek AM. Expansion of phenotype and genotypic data in CRB2-related syndrome. Eur J Hum Genet. 2016 10; 24(10):1436-44. PMID: 27004616.
    Citations: 9     Fields:    Translation:Humans
  30. Wessel AE, Mogensen KM, Rohr F, Erick M, Neilan EG, Chopra S, Levy HL, Gray KJ, Wilkins-Haug L, Berry GT. Management of a Woman With Maple Syrup Urine Disease During Pregnancy, Delivery, and Lactation. JPEN J Parenter Enteral Nutr. 2015 Sep; 39(7):875-9. PMID: 24618664.
    Citations: 6     Fields:    Translation:Humans
  31. Johnson KM, Swenson L, Opipari AW, Reuter R, Zarrabi N, Fierke CA, Börsch M, Glick GD. Mechanistic basis for differential inhibition of the F1Fo-ATPase by aurovertin. Biopolymers. 2009 Oct; 91(10):830-40. PMID: 19462418.
    Citations: 12     Fields:    Translation:AnimalsCells
  32. Cleary J, Johnson KM, Opipari AW, Glick GD. Inhibition of the mitochondrial F1F0-ATPase by ligands of the peripheral benzodiazepine receptor. Bioorg Med Chem Lett. 2007 Mar 15; 17(6):1667-70. PMID: 17251020.
    Citations: 18     Fields:    Translation:HumansCells
  33. Johnson KM, Cleary J, Fierke CA, Opipari AW, Glick GD. Mechanistic basis for therapeutic targeting of the mitochondrial F1F0-ATPase. ACS Chem Biol. 2006 Jun 20; 1(5):304-8. PMID: 17163759.
    Citations: 17     Fields:    Translation:Animals
  34. Johnson KM, Chen X, Boitano A, Swenson L, Opipari AW, Glick GD. Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423. Chem Biol. 2005 Apr; 12(4):485-96. PMID: 15850986.
    Citations: 46     Fields:    Translation:HumansAnimalsCells
  35. Schuster MC, Mann DA, Buchholz TJ, Johnson KM, Thomas WD, Kiessling LL. Parallel synthesis of glycomimetic libraries: targeting a C-type lectin. Org Lett. 2003 May 01; 5(9):1407-10. PMID: 12713285.
    Citations: 7     Fields:    Translation:Cells
  36. Blatt NB, Bednarski JJ, Warner RE, Leonetti F, Johnson KM, Boitano A, Yung R, Richardson BC, Johnson KJ, Ellman JA, Opipari AW, Glick GD. Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility. J Clin Invest. 2002 Oct; 110(8):1123-32. PMID: 12393848.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.