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Neena B. Haider, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EY027921 (WEINER, HOWARD L) Sep 30, 2017 - Jun 30, 2020
    NIH/NEI
    Role of Microglia in Retinitis Pigementosa
    Role: Co-Principal Investigator
  2. R01EY017653 (HAIDER, NEENA B) Dec 1, 2008 - Sep 30, 2012
    NIH/NEI
    Genetic Modifiers of Photoreceptor Development and Maintenance
    Role: Principal Investigator
  3. P20RR018788 (SMITH, SHELLEY D.) Sep 30, 2003 - Jun 30, 2014
    NIH/NCRR
    The Molecular Biology of Neurosurgery Systems
    Role: Co-Principal Investigator
  4. F32EY007080 (HAIDER, NEENA B) Dec 8, 2000
    NIH/NEI
    FUNCTIONAL STUDIES OFNR2E3 IN RETINAL DEVELOPMENT
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li S, Datta S, Brabbit E, Love Z, Woytowicz V, Flattery K, Capri J, Yao K, Wu S, Imboden M, Upadhyay A, Arumugham R, Thoreson WB, DeAngelis MM, Haider NB. Nr2e3 is a genetic modifier that rescues retinal degeneration and promotes homeostasis in multiple models of retinitis pigmentosa. Gene Ther. 2020 Mar 02. PMID: 32123325.
    Citations: 2     Fields:    
  2. Williams LB, Javed A, Sabri A, Morgan DJ, Huff CD, Grigg JR, Heng XT, Khng AJ, Hollink IHIM, Morrison MA, Owen LA, Anderson K, Kinard K, Greenlees R, Novacic D, Nida Sen H, Zein WM, Rodgers GM, Vitale AT, Haider NB, Hillmer AM, Ng PC, Cheng A, Zheng L, Gillies MC, van Slegtenhorst M, van Hagen PM, Missotten TOAR, Farley GL, Polo M, Malatack J, Curtin J, Martin F, Arbuckle S, Alexander SI, Chircop M, Davila S, Digre KB, Jamieson RV, DeAngelis MM. ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder. Genet Med. 2019 09; 21(9):2103-2115. PMID: 30967659.
    Citations: 1     Fields:    Translation:Humans
  3. Olivares AM, Althoff K, Chen GF, Wu S, Morrisson MA, DeAngelis MM, Haider N. Animal Models of Diabetic Retinopathy. Curr Diab Rep. 2017 08 24; 17(10):93. PMID: 28836097.
    Citations: 19     Fields:    Translation:HumansAnimals
  4. Olivares AM, Han Y, Soto D, Flattery K, Marini J, Molemma N, Haider A, Escher P, DeAngelis MM, Haider NB. Corrigendum to "The Nuclear Hormone Receptor Nr2c1 (Tr2) is a critical regulator of early retina cell pattering" [Dev. Biol. 16 (2017) 30797-7]. Dev Biol. 2017 09 01; 429(1):370. PMID: 28743516.
    Citations: 1     Fields:    
  5. Olivares AM, Han Y, Soto D, Flattery K, Marini J, Mollema N, Haider A, Escher P, DeAngelis MM, Haider NB. The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning. Dev Biol. 2017 09 01; 429(1):343-355. PMID: 28551284.
    Citations: 5     Fields:    Translation:AnimalsCells
  6. Olivares AM, Jelcick AS, Reinecke J, Leehy B, Haider A, Morrison MA, Cheng L, Chen DF, DeAngelis MM, Haider NB. Multimodal Regulation Orchestrates Normal and Complex Disease States in the Retina. Sci Rep. 2017 04 06; 7(1):690. PMID: 28386079.
    Citations: 3     Fields:    Translation:HumansCells
  7. Olivares AM, Moreno-Ramos OA, Haider NB. Role of Nuclear Receptors in Central Nervous System Development and Associated Diseases. J Exp Neurosci. 2015; 9(Suppl 2):93-121. PMID: 27168725.
    Citations: 6     
  8. Grishchuk Y, Stember KG, Matsunaga A, Olivares AM, Cruz NM, King VE, Humphrey DM, Wang SL, Muzikansky A, Betensky RA, Thoreson WB, Haider N, Slaugenhaupt SA. Retinal Dystrophy and Optic Nerve Pathology in the Mouse Model of Mucolipidosis IV. Am J Pathol. 2016 Jan; 186(1):199-209. PMID: 26608452.
    Citations: 4     Fields:    Translation:Animals
  9. Moreno-Ramos OA, Olivares AM, Haider NB, de Autismo LC, Lattig MC. Whole-Exome Sequencing in a South American Cohort Links ALDH1A3, FOXN1 and Retinoic Acid Regulation Pathways to Autism Spectrum Disorders. PLoS One. 2015; 10(9):e0135927. PMID: 26352270.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  10. von Alpen D, Tran HV, Guex N, Venturini G, Munier FL, Schorderet DF, Haider NB, Escher P. Differential dimerization of variants linked to enhanced S-cone sensitivity syndrome (ESCS) located in the NR2E3 ligand-binding domain. Hum Mutat. 2015 Jun; 36(6):599-610. PMID: 25703721.
    Citations: 4     Fields:    Translation:HumansCells
  11. Hasegawa E, Sweigard H, Husain D, Olivares AM, Chang B, Smith KE, Birsner AE, D'Amato RJ, Michaud NA, Han Y, Vavvas DG, Miller JW, Haider NB, Connor KM. Characterization of a spontaneous retinal neovascular mouse model. PLoS One. 2014; 9(9):e106507. PMID: 25188381.
    Citations: 14     Fields:    Translation:Animals
  12. Owen LA, Morrison MA, Ahn J, Woo SJ, Sato H, Robinson R, Morgan DJ, Zacharaki F, Simeonova M, Uehara H, Chakravarthy U, Hogg RE, Ambati BK, Kotoula M, Baehr W, Haider NB, Silvestri G, Miller JW, Tsironi EE, Farrer LA, Kim IK, Park KH, DeAngelis MM. FLT1 genetic variation predisposes to neovascular AMD in ethnically diverse populations and alters systemic FLT1 expression. Invest Ophthalmol Vis Sci. 2014 May 08; 55(6):3543-54. PMID: 24812550.
    Citations: 5     Fields:    Translation:HumansAnimals
  13. Cruz NM, Yuan Y, Leehy BD, Baid R, Kompella U, DeAngelis MM, Escher P, Haider NB. Modifier genes as therapeutics: the nuclear hormone receptor Rev Erb alpha (Nr1d1) rescues Nr2e3 associated retinal disease. PLoS One. 2014; 9(1):e87942. PMID: 24498227.
    Citations: 13     Fields:    Translation:HumansAnimals
  14. Kador PF, Zhang P, Makita J, Zhang Z, Guo C, Randazzo J, Kawada H, Haider N, Blessing K. Novel diabetic mouse models as tools for investigating diabetic retinopathy. PLoS One. 2012; 7(12):e49422. PMID: 23251343.
    Citations: 7     Fields:    Translation:Animals
  15. Jun G, Nicolaou M, Morrison MA, Buros J, Morgan DJ, Radeke MJ, Yonekawa Y, Tsironi EE, Kotoula MG, Zacharaki F, Mollema N, Yuan Y, Miller JW, Haider NB, Hageman GS, Kim IK, Schaumberg DA, Farrer LA, DeAngelis MM. Influence of ROBO1 and RORA on risk of age-related macular degeneration reveals genetically distinct phenotypes in disease pathophysiology. PLoS One. 2011; 6(10):e25775. PMID: 21998696.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  16. Morrison MA, Silveira AC, Huynh N, Jun G, Smith SE, Zacharaki F, Sato H, Loomis S, Andreoli MT, Adams SM, Radeke MJ, Jelcick AS, Yuan Y, Tsiloulis AN, Chatzoulis DZ, Silvestri G, Kotoula MG, Tsironi EE, Hollis BW, Chen R, Haider NB, Miller JW, Farrer LA, Hageman GS, Kim IK, Schaumberg DA, DeAngelis MM. Systems biology-based analysis implicates a novel role for vitamin D metabolism in the pathogenesis of age-related macular degeneration. Hum Genomics. 2011 Oct; 5(6):538-68. PMID: 22155603.
    Citations: 22     Fields:    Translation:Humans
  17. Jelcick AS, Yuan Y, Leehy BD, Cox LC, Silveira AC, Qiu F, Schenk S, Sachs AJ, Morrison MA, Nystuen AM, DeAngelis MM, Haider NB. Genetic variations strongly influence phenotypic outcome in the mouse retina. PLoS One. 2011; 6(7):e21858. PMID: 21779340.
    Citations: 20     Fields:    Translation:AnimalsCells
  18. Randazzo J, Zhang Z, Hoff M, Kawada H, Sachs A, Yuan Y, Haider N, Kador P. Orally active multi-functional antioxidants are neuroprotective in a rat model of light-induced retinal damage. PLoS One. 2011; 6(7):e21926. PMID: 21779355.
    Citations: 5     Fields:    Translation:AnimalsCells
  19. Mollema NJ, Yuan Y, Jelcick AS, Sachs AJ, von Alpen D, Schorderet D, Escher P, Haider NB. Nuclear receptor Rev-erb alpha (Nr1d1) functions in concert with Nr2e3 to regulate transcriptional networks in the retina. PLoS One. 2011 Mar 08; 6(3):e17494. PMID: 21408158.
    Citations: 25     Fields:    Translation:AnimalsCells
  20. Mollema N, Haider NB. Focus on molecules: nuclear hormone receptor Nr2e3: impact on retinal development and disease. Exp Eye Res. 2010 Aug; 91(2):116-7. PMID: 20450910.
    Citations: 7     Fields:    Translation:Humans
  21. Duke SL, Kump LI, Yuan Y, West WW, Sachs AJ, Haider NB, Margalit E. The safety of intraocular linezolid in rabbits. Invest Ophthalmol Vis Sci. 2010 Jun; 51(6):3115-9. PMID: 20042664.
    Citations: 5     Fields:    Translation:Animals
  22. Sachs AJ, David SA, Haider NB, Nystuen AM. Patterned neuroprotection in the Inpp4a(wbl) mutant mouse cerebellum correlates with the expression of Eaat4. PLoS One. 2009 Dec 14; 4(12):e8270. PMID: 20011524.
    Citations: 8     Fields:    Translation:AnimalsCells
  23. Silveira AC, Morrison MA, Ji F, Xu H, Reinecke JB, Adams SM, Arneberg TM, Janssian M, Lee JE, Yuan Y, Schaumberg DA, Kotoula MG, Tsironi EE, Tsiloulis AN, Chatzoulis DZ, Miller JW, Kim IK, Hageman GS, Farrer LA, Haider NB, DeAngelis MM. Convergence of linkage, gene expression and association data demonstrates the influence of the RAR-related orphan receptor alpha (RORA) gene on neovascular AMD: a systems biology based approach. Vision Res. 2010 Mar 31; 50(7):698-715. PMID: 19786043.
    Citations: 26     Fields:    Translation:Humans
  24. Haider NB, Mollema N, Gaule M, Yuan Y, Sachs AJ, Nystuen AM, Naggert JK, Nishina PM. Nr2e3-directed transcriptional regulation of genes involved in photoreceptor development and cell-type specific phototransduction. Exp Eye Res. 2009 Sep; 89(3):365-72. PMID: 19379737.
    Citations: 33     Fields:    Translation:AnimalsCells
  25. Nystuen AM, Sachs AJ, Yuan Y, Heuermann L, Haider NB. A novel mutation in Prph2, a gene regulated by Nr2e3, causes retinal degeneration and outer-segment defects similar to Nr2e3 ( rd7/rd7 ) retinas. Mamm Genome. 2008 Sep; 19(9):623-33. PMID: 18763016.
    Citations: 10     Fields:    Translation:AnimalsCells
  26. Haider NB, Zhang W, Hurd R, Ikeda A, Nystuen AM, Naggert JK, Nishina PM. Mapping of genetic modifiers of Nr2e3 rd7/rd7 that suppress retinal degeneration and restore blue cone cells to normal quantity. Mamm Genome. 2008 Mar; 19(3):145-54. PMID: 18286335.
    Citations: 18     Fields:    Translation:AnimalsCells
  27. Sachs AJ, Schwendinger JK, Yang AW, Haider NB, Nystuen AM. The mouse mutants recoil wobbler and nmf373 represent a series of Grm1 mutations. Mamm Genome. 2007 Nov; 18(11):749-56. PMID: 17934773.
    Citations: 11     Fields:    Translation:AnimalsCells
  28. Nystuen AM, Schwendinger JK, Sachs AJ, Yang AW, Haider NB. A null mutation in VAMP1/synaptobrevin is associated with neurological defects and prewean mortality in the lethal-wasting mouse mutant. Neurogenetics. 2007 Jan; 8(1):1-10. PMID: 17102983.
    Citations: 26     Fields:    Translation:AnimalsCells
  29. Haider NB, Demarco P, Nystuen AM, Huang X, Smith RS, McCall MA, Naggert JK, Nishina PM. The transcription factor Nr2e3 functions in retinal progenitors to suppress cone cell generation. Vis Neurosci. 2006 Nov-Dec; 23(6):917-29. PMID: 17266784.
    Citations: 33     Fields:    Translation:AnimalsCells
  30. Mehalow AK, Kameya S, Smith RS, Hawes NL, Denegre JM, Young JA, Bechtold L, Haider NB, Tepass U, Heckenlively JR, Chang B, Naggert JK, Nishina PM. CRB1 is essential for external limiting membrane integrity and photoreceptor morphogenesis in the mammalian retina. Hum Mol Genet. 2003 Sep 01; 12(17):2179-89. PMID: 12915475.
    Citations: 135     Fields:    Translation:AnimalsCells
  31. Haider NB, Ikeda A, Naggert JK, Nishina PM. Genetic modifiers of vision and hearing. Hum Mol Genet. 2002 May 15; 11(10):1195-206. PMID: 12015279.
    Citations: 18     Fields:    Translation:HumansAnimals
  32. Haider NB, Naggert JK, Nishina PM. Excess cone cell proliferation due to lack of a functional NR2E3 causes retinal dysplasia and degeneration in rd7/rd7 mice. Hum Mol Genet. 2001 Aug 01; 10(16):1619-26. PMID: 11487564.
    Citations: 72     Fields:    Translation:HumansAnimalsCells
  33. Mykytyn K, Braun T, Carmi R, Haider NB, Searby CC, Shastri M, Beck G, Wright AF, Iannaccone A, Elbedour K, Riise R, Baldi A, Raas-Rothschild A, Gorman SW, Duhl DM, Jacobson SG, Casavant T, Stone EM, Sheffield VC. Identification of the gene that, when mutated, causes the human obesity syndrome BBS4. Nat Genet. 2001 Jun; 28(2):188-91. PMID: 11381270.
    Citations: 78     Fields:    Translation:Humans
  34. Nishimura DY, Searby CC, Carmi R, Elbedour K, Van Maldergem L, Fulton AB, Lam BL, Powell BR, Swiderski RE, Bugge KE, Haider NB, Kwitek-Black AE, Ying L, Duhl DM, Gorman SW, Heon E, Iannaccone A, Bonneau D, Biesecker LG, Jacobson SG, Stone EM, Sheffield VC. Positional cloning of a novel gene on chromosome 16q causing Bardet-Biedl syndrome (BBS2). Hum Mol Genet. 2001 Apr 01; 10(8):865-74. PMID: 11285252.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  35. Kolodgie FD, Narula J, Haider N, Virmani R. Apoptosis in atherosclerosis. Does it contribute to plaque instability? Cardiol Clin. 2001 Feb; 19(1):127-39, ix. PMID: 11787806.
    Citations: 12     Fields:    Translation:Humans
  36. Kolodgie FD, Narula J, Burke AP, Haider N, Farb A, Hui-Liang Y, Smialek J, Virmani R. Localization of apoptotic macrophages at the site of plaque rupture in sudden coronary death. Am J Pathol. 2000 Oct; 157(4):1259-68. PMID: 11021830.
    Citations: 71     Fields:    Translation:HumansCells
  37. Miano MG, Jacobson SG, Carothers A, Hanson I, Teague P, Lovell J, Cideciyan AV, Haider N, Stone EM, Sheffield VC, Wright AF. Pitfalls in homozygosity mapping. Am J Hum Genet. 2000 Nov; 67(5):1348-51. PMID: 11007652.
    Citations: 21     Fields:    Translation:HumansCells
  38. Haider NB, Jacobson SG, Cideciyan AV, Swiderski R, Streb LM, Searby C, Beck G, Hockey R, Hanna DB, Gorman S, Duhl D, Carmi R, Bennett J, Weleber RG, Fishman GA, Wright AF, Stone EM, Sheffield VC. Mutation of a nuclear receptor gene, NR2E3, causes enhanced S cone syndrome, a disorder of retinal cell fate. Nat Genet. 2000 Feb; 24(2):127-31. PMID: 10655056.
    Citations: 152     Fields:    Translation:HumansAnimalsCells
  39. Ying L, Katz Y, Schlesinger M, Carmi R, Shalev H, Haider N, Beck G, Sheffield VC, Landau D. Complement factor H gene mutation associated with autosomal recessive atypical hemolytic uremic syndrome. Am J Hum Genet. 1999 Dec; 65(6):1538-46. PMID: 10577907.
    Citations: 23     Fields:    Translation:HumansCells
  40. Haider NB, Searby C, Galperin E, Mintz L, Horowitz M, Stone EM, Sheffield VC. Evaluation and molecular characterization of EHD1, a candidate gene for Bardet-Biedl syndrome 1 (BBS1). Gene. 1999 Nov 15; 240(1):227-32. PMID: 10564830.
    Citations: 3     Fields:    Translation:HumansCells
  41. Gorman SW, Haider NB, Grieshammer U, Swiderski RE, Kim E, Welch JW, Searby C, Leng S, Carmi R, Sheffield VC, Duhl DM. The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23. Genomics. 1999 Jul 15; 59(2):150-60. PMID: 10409426.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  42. Narula J, Pandey P, Arbustini E, Haider N, Narula N, Kolodgie FD, Dal Bello B, Semigran MJ, Bielsa-Masdeu A, Dec GW, Israels S, Ballester M, Virmani R, Saxena S, Kharbanda S. Apoptosis in heart failure: release of cytochrome c from mitochondria and activation of caspase-3 in human cardiomyopathy. Proc Natl Acad Sci U S A. 1999 Jul 06; 96(14):8144-9. PMID: 10393962.
    Citations: 132     Fields:    Translation:HumansAnimalsCells
  43. Dewanjee MK, Haider N, Narula J. Imaging with radiolabeled antisense oligonucleotides for the detection of intracellular messenger RNA and cardiovascular disease. J Nucl Cardiol. 1999 May-Jun; 6(3):345-56. PMID: 10385190.
    Citations: 4     Fields:    Translation:Cells
  44. Haider NB, Carmi R, Shalev H, Sheffield VC, Landau D. A Bedouin kindred with infantile nephronophthisis demonstrates linkage to chromosome 9 by homozygosity mapping. Am J Hum Genet. 1998 Nov; 63(5):1404-10. PMID: 9792867.
    Citations: 17     Fields:    Translation:HumansCells
  45. Narula N, Haider N, Narula J. Cell biology for the nuclear cardiologist. J Nucl Cardiol. 1998 Jul-Aug; 5(4):426-37. PMID: 9715988.
    Citations: 2     Fields:    Translation:HumansCells
  46. Haider N, Iyer RR, Narula J. Topics in molecular biology. Techniques and methods. J Nucl Cardiol. 1998 May-Jun; 5(3):343-54. PMID: 9669588.
    Citations: 2     Fields:    Translation:HumansAnimals
  47. Iyer RR, Schelbert H, Haider N, Narula J. Molecular biology for the nuclear cardiologist: terminology, concepts, and processes. J Nucl Cardiol. 1998 Mar-Apr; 5(2):184-94. PMID: 9588670.
    Citations: 2     Fields:    Translation:HumansCells
  48. Nystuen A, Costeff H, Elpeleg ON, Apter N, Bonné-Tamir B, Mohrenweiser H, Haider N, Stone EM, Sheffield VC. Iraqi-Jewish kindreds with optic atrophy plus (3-methylglutaconic aciduria type 3) demonstrate linkage disequilibrium with the CTG repeat in the 3' untranslated region of the myotonic dystrophy protein kinase gene. Hum Mol Genet. 1997 Apr; 6(4):563-9. PMID: 9097959.
    Citations: 7     Fields:    Translation:HumansCells
  49. Narula J, Haider N, Virmani R, DiSalvo TG, Kolodgie FD, Hajjar RJ, Schmidt U, Semigran MJ, Dec GW, Khaw BA. Apoptosis in myocytes in end-stage heart failure. N Engl J Med. 1996 Oct 17; 335(16):1182-9. PMID: 8815940.
    Citations: 271     Fields:    Translation:Humans
  50. Bhol K, Udell I, Haider N, Yunis JJ, Mohimen A, Neuman R, Grasso C, Ahmed AR, Foster S. Ocular cicatricial pemphigoid. A case report of monozygotic twins discordant for the disease. Arch Ophthalmol. 1995 Feb; 113(2):202-7. PMID: 7864752.
    Citations: 2     Fields:    Translation:HumansCells
  51. Haider N, Neuman R, Foster CS, Ahmed AR. Report on the sequence of DQB1*0301 gene in ocular cicatricial pemphigoid patients. Curr Eye Res. 1992 Dec; 11(12):1233-8. PMID: 1490342.
    Citations: 1     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.