Dr. Leaf is an Assistant Professor of Medicine at Harvard Medical School and the Director of Clinical and Translational Research in Acute Kidney Injury in the Division of Renal Medicine at Brigham and Women’s Hospital. He conducts patient-oriented research in acute kidney injury (AKI) and critical illness. He uses epidemiologic, translational, genetic, and interventional approaches to address clinically important questions in patients with AKI. Current areas of investigation include dysregulated mineral and iron homeostasis as novel pathways and potential therapeutic targets in AKI, as well as investigation of the nephrotoxicity of novel cancer therapies.
Dr. Leaf is the principal investigator on two R01 grants. He serves on the Editorial Boards of Kidney International and Clinical Journal of the American Society of Nephrology, and is a member of the Mass General Brigham Institutional Review Board. His publications have appeared in leading medical journals including the New England Journal of Medicine, BMJ, JAMA Internal Medicine, Nature Medicine, Journal of Clinical Investigation, Journal of the American Society of Nephrology, and Kidney International. His research has been featured in national media including The New York Times, Washington Post, USA today, CNN, and NPR.
Dr. Leaf is passionate about academic nephrology, and has received research and teaching awards from NYU, Columbia, and Harvard. He enjoys spending time with his wife (Rebecca), his two children (Emma and Teddy), his cat (Winston), as well as traveling, skiing, swimming, and playing chess.