Christopher Yuskaitis, M.D., Ph.D.
Instructor in Neurology
Boston Children's Hospital
Cls14030.12, Bch 3149
3 Blackfan Circle
Boston MA 02115
Available: 10/26/20, Expires: 10/01/21
We are studying genes regulating how cells sense nutrients through the mTOR pathway. Manipulation of genes in this pathway lead to brain malformations and epilepsy. Important questions remain including 1) are brain malformations and epilepsy mutually exclusive (i.e. do you need a malformation to have epilepsy), and 2) can we manipulate nutrients to protect from seizures?
Students role: Independent project creating a transgenic animal model and evaluating the predisposition to seizures and the underlying molecular mechanisms.
Required skills: Experience working with rodents is a plus. Any experience performing immunohistochemistry and imaging, not necessary but helpful.
PI availability: I meet with students and RAs weekly but I am also available everyday in the lab for teaching, technical problems, and discussion.
Location: The project is located in Center for Life Sciences building 12 and 14th floors. The project requires in-person participation within the laboratory.
The research activities and funding listed below are automatically derived from
NIH ExPORTER and other sources, which might result in incorrect or missing items.
to make corrections and additions.
(YUSKAITIS, CHRISTOPHER JOSEPH)
Jul 1, 2019 - Apr 30, 2024
The Role of DEPDC5 in Epileptogenesis and Brain Malformations
Role: Principal Investigator
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