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profileBrian Curran Healy, Ph.D.

TitleAssistant Professor of Neurology
InstitutionBrigham and Women's Hospital
DepartmentNeurology
AddressHarvard School of Public Health
Kresge Bldg
677 Huntington Ave
Boston MA 02115
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Other Positions
TitleAssistant Professor in the Department of Biostatistics
InstitutionHarvard T.H. Chan School of Public Health
DepartmentBiostatistics


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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Greeke EE, Chua AS, Healy BC, Rintell DJ, Chitnis T, Glanz BI. Depression and fatigue in patients with multiple sclerosis. J Neurol Sci. 2017 Sep 15; 380:236-241. PMID: 28870578.
    View in: PubMed
  2. Sattarnezhad N, Farrow S, Kimbrough D, Glanz B, Healy B, Chitnis T. Agreement analysis comparing iPad LCVA and Sloan testing in multiple sclerosis patients. Mult Scler. 2017 Jun 01; 1352458517713667. PMID: 28585909.
    View in: PubMed
  3. Tummala S, Singhal T, Oommen VV, Kim G, Khalid F, Healy BC, Bakshi R. Spinal Cord as an Adjunct to Brain Magnetic Resonance Imaging in Defining "No Evidence of Disease Activity" in Multiple Sclerosis. Int J MS Care. 2017 May-Jun; 19(3):158-164. PMID: 28603465.
    View in: PubMed
  4. Zhao Y, Healy BC, Rotstein D, Guttmann CR, Bakshi R, Weiner HL, Brodley CE, Chitnis T. Exploration of machine learning techniques in predicting multiple sclerosis disease course. PLoS One. 2017; 12(4):e0174866. PMID: 28379999.
    View in: PubMed
  5. Celano CM, Beale EE, Beach SR, Belcher AM, Suarez L, Motiwala SR, Gandhi PU, Gaggin H, Januzzi JL, Healy BC, Huffman JC. Associations Between Psychological Constructs and Cardiac Biomarkers After Acute Coronary Syndrome. Psychosom Med. 2017 Apr; 79(3):318-326. PMID: 27749683.
    View in: PubMed
  6. Healy BC, Buckle GJ, Ali EN, Egorova S, Khalid F, Tauhid S, Glanz BI, Chitnis T, Guttmann CRG, Weiner HL, Bakshi R. Characterizing Clinical and MRI Dissociation in Patients with Multiple Sclerosis. J Neuroimaging. 2017 Sep; 27(5):481-485. PMID: 28261936.
    View in: PubMed
  7. Regev K, Healy BC, Khalid F, Paul A, Chu R, Tauhid S, Tummala S, Diaz-Cruz C, Raheja R, Mazzola MA, von Glehn F, Kivisakk P, Dupuy SL, Kim G, Chitnis T, Weiner HL, Gandhi R, Bakshi R. Association Between Serum MicroRNAs and Magnetic Resonance Imaging Measures of Multiple Sclerosis Severity. JAMA Neurol. 2017 Mar 01; 74(3):275-285. PMID: 28114622.
    View in: PubMed
  8. Kim G, Chu R, Yousuf F, Tauhid S, Stazzone L, Houtchens MK, Stankiewicz JM, Severson C, Kimbrough D, Quintana FJ, Chitnis T, Weiner HL, Healy BC, Bakshi R. Sample size requirements for one-year treatment effects using deep gray matter volume from 3T MRI in progressive forms of multiple sclerosis. Int J Neurosci. 2017 Nov; 127(11):971-980. PMID: 28100092.
    View in: PubMed
  9. Bargiela D, Bianchi MT, Westover MB, Chibnik LB, Healy BC, De Jager PL, Xia Z. Selection of first-line therapy in multiple sclerosis using risk-benefit decision analysis. Neurology. 2017 Feb 14; 88(7):677-684. PMID: 28087821.
    View in: PubMed
  10. Huffman JC, Albanese AM, Campbell KA, Celano CM, Millstein RA, Mastromauro CA, Healy BC, Chung WJ, Januzzi JL, Collins LM, Park ER. The Positive Emotions after Acute Coronary Events behavioral health intervention: Design, rationale, and preliminary feasibility of a factorial design study. Clin Trials. 2017 Apr; 14(2):128-139. PMID: 28079394.
    View in: PubMed
  11. Dupuy SL, Khalid F, Healy BC, Bakshi S, Neema M, Tauhid S, Bakshi R. The effect of intramuscular interferon beta-1a on spinal cord volume in relapsing-remitting multiple sclerosis. BMC Med Imaging. 2016 Oct 05; 16(1):56. PMID: 27716096.
    View in: PubMed
  12. Schwartz CE, Rapkin BD, Healy BC. Reserve and Reserve-building activities research: key challenges and future directions. BMC Neurosci. 2016 Sep 15; 17(1):62. PMID: 27633657.
    View in: PubMed
  13. Glanz BI, Greeke E, LaRussa A, Stuart F, Rintell DJ, Chitnis T, Healy BC. Risk attitudes and risk perceptions in individuals with multiple sclerosis. Mult Scler J Exp Transl Clin. 2016 Jan-Dec; 2:2055217316665406. PMID: 28607735.
    View in: PubMed
  14. Regev K, Paul A, Healy B, von Glenn F, Diaz-Cruz C, Gholipour T, Mazzola MA, Raheja R, Nejad P, Glanz BI, Kivisakk P, Chitnis T, Weiner HL, Gandhi R. Comprehensive evaluation of serum microRNAs as biomarkers in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2016 Oct; 3(5):e267. PMID: 27606352; PMCID: PMC4996540.
    View in: PubMed, PubMed Central
  15. Healy BC, Weinshenker BG. Does early (treatment in) BENEFIT lead to late MS benefit? Neurology. 2016 Sep 06; 87(10):970-1. PMID: 27511185.
    View in: PubMed
  16. Yousuf F, Kim G, Tauhid S, Glanz BI, Chu R, Tummala S, Healy BC, Bakshi R. The Contribution of Cortical Lesions to a Composite MRI Scale of Disease Severity in Multiple Sclerosis. Front Neurol. 2016; 7:99. PMID: 27445966; PMCID: PMC4925661.
    View in: PubMed, PubMed Central
  17. Bove R, Musallam A, Xia Z, Baruch N, Messina S, Healy BC, Chitnis T. Longitudinal BMI trajectories in multiple sclerosis: Sex differences in association with disease severity. Mult Scler Relat Disord. 2016 Jul; 8:136-40. PMID: 27456889.
    View in: PubMed
  18. Khalid F, Tauhid S, Chua AS, Healy BC, Stankiewicz JM, Weiner HL, Bakshi R. A longitudinal uncontrolled study of cerebral gray matter volume in patients receiving natalizumab for multiple sclerosis. Int J Neurosci. 2017 May; 127(5):396-403. PMID: 27143245.
    View in: PubMed
  19. Huffman JC, Boehm JK, Beach SR, Beale EE, DuBois CM, Healy BC. Relationship of optimism and suicidal ideation in three groups of patients at varying levels of suicide risk. J Psychiatr Res. 2016 Jun; 77:76-84. PMID: 26994340; PMCID: PMC4841259 [Available on 06/01/17].
    View in: PubMed, PubMed Central
  20. Laíns I, Bartosch C, Mondim V, Healy B, Kim IK, Husain D, Miller JW. Second Primary Neoplasms in Patients With Uveal Melanoma: A SEER Database Analysis. Am J Ophthalmol. 2016 May; 165:54-64. PMID: 26940164.
    View in: PubMed
  21. Cavallari M, Palotai M, Glanz BI, Egorova S, Prieto JC, Healy BC, Chitnis T, Guttmann CR. Fatigue predicts disease worsening in relapsing-remitting multiple sclerosis patients. Mult Scler. 2016 Dec; 22(14):1841-1849. PMID: 26920374.
    View in: PubMed
  22. Celano CM, Healy B, Suarez L, Levy DE, Mastromauro C, Januzzi JL, Huffman JC. Cost-Effectiveness of a Collaborative Care Depression and Anxiety Treatment Program in Patients with Acute Cardiac Illness. Value Health. 2016 Mar-Apr; 19(2):185-91. PMID: 27021752.
    View in: PubMed
  23. Kim G, Tauhid S, Dupuy SL, Tummala S, Khalid F, Healy BC, Bakshi R. An MRI-defined measure of cerebral lesion severity to assess therapeutic effects in multiple sclerosis. J Neurol. 2016 Mar; 263(3):531-8. PMID: 26754005; PMCID: PMC4785194.
    View in: PubMed, PubMed Central
  24. Rotstein DL, Healy BC, Malik MT, Carruthers RL, Musallam AJ, Kivisakk P, Weiner HL, Glanz B, Chitnis T. Effect of vitamin D on MS activity by disease-modifying therapy class. Neurol Neuroimmunol Neuroinflamm. 2015 Dec; 2(6):e167. PMID: 26568968; PMCID: PMC4630683.
    View in: PubMed, PubMed Central
  25. Oommen VV, Tauhid S, Healy BC, Chua AS, Malik MT, Diaz-Cruz C, Dupuy SL, Weiner HL, Chitnis T, Bakshi R. The Effect of Fingolimod on Conversion of Acute Gadolinium-Enhancing Lesions to Chronic T1 Hypointensities in Multiple Sclerosis. J Neuroimaging. 2016 Mar-Apr; 26(2):184-7. PMID: 26445919.
    View in: PubMed
  26. Bove R, Healy BC, Musallam A, Glanz BI, De Jager PL, Chitnis T. Exploration of changes in disability after menopause in a longitudinal multiple sclerosis cohort. Mult Scler. 2016 Jun; 22(7):935-43. PMID: 26447063; PMCID: PMC4824677 [Available on 06/01/17].
    View in: PubMed, PubMed Central
  27. Chua AS, Glanz BI, Guarino AJ, Cook SL, Greeke EE, Little GE, Chitnis T, Healy BC. Patient-reported outcomes in multiple sclerosis: Relationships among existing scales and the development of a brief measure. Mult Scler Relat Disord. 2015 Nov; 4(6):598-606. PMID: 26590669.
    View in: PubMed
  28. Celano CM, Millstein RA, Bedoya CA, Healy BC, Roest AM, Huffman JC. Association between anxiety and mortality in patients with coronary artery disease: A meta-analysis. Am Heart J. 2015 Dec; 170(6):1105-15. PMID: 26678632; PMCID: PMC4684590 [Available on 12/01/16].
    View in: PubMed, PubMed Central
  29. Bove R, Malik MT, Diaz-Cruz C, Chua A, Saraceno TJ, Bargiela D, Greeke E, Glanz BI, Healy BC, Chitnis T. The 2D:4D ratio, a proxy for prenatal androgen levels, differs in men with and without MS. Neurology. 2015 Oct 06; 85(14):1209-13. PMID: 26341868; PMCID: PMC4607599 [Available on 10/06/16].
    View in: PubMed, PubMed Central
  30. Kim G, Khalid F, Oommen VV, Tauhid S, Chu R, Horsfield MA, Healy BC, Bakshi R. T1- vs. T2-based MRI measures of spinal cord volume in healthy subjects and patients with multiple sclerosis. BMC Neurol. 2015 Jul 31; 15:124. PMID: 26227960; PMCID: PMC4521382.
    View in: PubMed, PubMed Central
  31. Tauhid S, Chu R, Sasane R, Glanz BI, Neema M, Miller JR, Kim G, Signorovitch JE, Healy BC, Chitnis T, Weiner HL, Bakshi R. Brain MRI lesions and atrophy are associated with employment status in patients with multiple sclerosis. J Neurol. 2015 Nov; 262(11):2425-32. PMID: 26205635; PMCID: PMC4639581.
    View in: PubMed, PubMed Central
  32. Liu J, Brodley CE, Healy BC, Chitnis T. Removing confounding factors via constraint-based clustering: An application to finding homogeneous groups of multiple sclerosis patients. Artif Intell Med. 2015 Oct; 65(2):79-88. PMID: 26253753.
    View in: PubMed
  33. Carruthers RL, Healy BC. PML in DMF-treated patients with normal lymphocytes: Worried well or well to be worried? Mult Scler. 2016 Mar; 22(3):394-5. PMID: 26163066.
    View in: PubMed
  34. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Handling changes in MRI acquisition parameters in modeling whole brain lesion volume and atrophy data in multiple sclerosis subjects: Comparison of linear mixed-effect models. Neuroimage Clin. 2015; 8:606-10. PMID: 26199872; PMCID: PMC4506959.
    View in: PubMed, PubMed Central
  35. Dobos K, Healy B, Houtchens M. Access to Preventive Health Care in Severely Disabled Women with Multiple Sclerosis. Int J MS Care. 2015 Jul-Aug; 17(4):200-5. PMID: 26300706; PMCID: PMC4542715.
    View in: PubMed, PubMed Central
  36. Chu R, Tauhid S, Glanz BI, Healy BC, Kim G, Oommen VV, Khalid F, Neema M, Bakshi R. Whole Brain Volume Measured from 1.5T versus 3T MRI in Healthy Subjects and Patients with Multiple Sclerosis. J Neuroimaging. 2016 Jan-Feb; 26(1):62-7. PMID: 26118637; PMCID: PMC4755143.
    View in: PubMed, PubMed Central
  37. Chua AS, Egorova S, Anderson MC, Polgar-Turcsanyi M, Chitnis T, Weiner HL, Guttmann CR, Bakshi R, Healy BC. Using multiple imputation to efficiently correct cerebral MRI whole brain lesion and atrophy data in patients with multiple sclerosis. Neuroimage. 2015 Oct 01; 119:81-8. PMID: 26093330.
    View in: PubMed
  38. Baruch NF, O'Donnell EH, Glanz BI, Benedict RH, Musallam AJ, Healy BC, Rintell D, Chitnis T. Cognitive and patient-reported outcomes in adults with pediatric-onset multiple sclerosis. Mult Scler. 2016 Mar; 22(3):354-61. PMID: 26041802.
    View in: PubMed
  39. Fernandez-Carbonell C, Vargas-Lowy D, Musallam A, Healy B, McLaughlin K, Wucherpfennig KW, Chitnis T. Clinical and MRI phenotype of children with MOG antibodies. Mult Scler. 2016 Feb; 22(2):174-84. PMID: 26041801; PMCID: PMC4669239 [Available on 02/01/17].
    View in: PubMed, PubMed Central
  40. DuBois CM, Lopez OV, Beale EE, Healy BC, Boehm JK, Huffman JC. Relationships between positive psychological constructs and health outcomes in patients with cardiovascular disease: A systematic review. Int J Cardiol. 2015 Sep 15; 195:265-80. PMID: 26048390; PMCID: PMC4487518.
    View in: PubMed, PubMed Central
  41. Engler D, Chitnis T, Healy B. Joint assessment of dependent discrete disease state processes. Stat Methods Med Res. 2017 Jun; 26(3):1182-1198. PMID: 25698716.
    View in: PubMed
  42. Rotstein DL, Healy BC, Malik MT, Chitnis T, Weiner HL. Evaluation of no evidence of disease activity in a 7-year longitudinal multiple sclerosis cohort. JAMA Neurol. 2015 Feb; 72(2):152-8. PMID: 25531931.
    View in: PubMed
  43. Dell'Oglio E, Ceccarelli A, Glanz BI, Healy BC, Tauhid S, Arora A, Saravanan N, Bruha MJ, Vartanian AV, Dupuy SL, Benedict RH, Bakshi R, Neema M. Quantification of global cerebral atrophy in multiple sclerosis from 3T MRI using SPM: the role of misclassification errors. J Neuroimaging. 2015 Mar-Apr; 25(2):191-9. PMID: 25523616; PMCID: PMC4409073.
    View in: PubMed, PubMed Central
  44. Bove R, Healy BC, Secor E, Vaughan T, Katic B, Chitnis T, Wicks P, De Jager PL. Patients report worse MS symptoms after menopause: findings from an online cohort. Mult Scler Relat Disord. 2015 Jan; 4(1):18-24. PMID: 25787049.
    View in: PubMed
  45. Bakshi R, Neema M, Tauhid S, Healy BC, Glanz BI, Kim G, Miller J, Berkowitz JL, Bove R, Houtchens MK, Severson C, Stankiewicz JM, Stazzone L, Chitnis T, Guttmann CR, Weiner HL, Ceccarelli A. An expanded composite scale of MRI-defined disease severity in multiple sclerosis: MRDSS2. Neuroreport. 2014 Oct 01; 25(14):1156-61. PMID: 25100554; PMCID: PMC4166046.
    View in: PubMed, PubMed Central
  46. Tauhid S, Neema M, Healy BC, Weiner HL, Bakshi R. MRI phenotypes based on cerebral lesions and atrophy in patients with multiple sclerosis. J Neurol Sci. 2014 Nov 15; 346(1-2):250-4. PMID: 25220114.
    View in: PubMed
  47. Raghavan K, Healy BC, Carruthers RL, Chitnis T. Progression rates and sample size estimates for PPMS based on the CLIMB study population. Mult Scler. 2015 Feb; 21(2):180-8. PMID: 25070676.
    View in: PubMed
  48. Huffman JC, Mastromauro CA, Beach SR, Celano CM, DuBois CM, Healy BC, Suarez L, Rollman BL, Januzzi JL. Collaborative care for depression and anxiety disorders in patients with recent cardiac events: the Management of Sadness and Anxiety in Cardiology (MOSAIC) randomized clinical trial. JAMA Intern Med. 2014 Jun; 174(6):927-35. PMID: 24733277.
    View in: PubMed
  49. Carruthers RL, Rotstein DL, Healy BC, Chitnis T, Weiner HL, Buckle GJ. An observational comparison of natalizumab vs. fingolimod using JCV serology to determine therapy. Mult Scler. 2014 Sep; 20(10):1381-90. PMID: 24852928.
    View in: PubMed
  50. Malik MT, Healy BC, Benson LA, Kivisakk P, Musallam A, Weiner HL, Chitnis T. Factors associated with recovery from acute optic neuritis in patients with multiple sclerosis. Neurology. 2014 Jun 17; 82(24):2173-9. PMID: 24850491; PMCID: PMC4113460.
    View in: PubMed, PubMed Central
  51. Bove R, Musallam A, Healy BC, Raghavan K, Glanz BI, Bakshi R, Weiner H, De Jager PL, Miller KK, Chitnis T. Low testosterone is associated with disability in men with multiple sclerosis. Mult Scler. 2014 Oct; 20(12):1584-92. PMID: 24710799; PMCID: PMC4188801.
    View in: PubMed, PubMed Central
  52. Glanz BI, Musallam A, Rintell DJ, Chitnis T, Weiner HL, Healy BC. Treatment satisfaction in multiple sclerosis. Int J MS Care. 2014; 16(2):68-75. PMID: 25061430; PMCID: PMC4106393.
    View in: PubMed, PubMed Central
  53. Russell K, Healy B, Pantarotto J, Laurie SA, MacRae R, Sabri E, Wheatley-Price P. Prognostic factors in the radical nonsurgical treatment of stage IIIB non-small-cell lung cancer. Clin Lung Cancer. 2014 May; 15(3):237-43. PMID: 24461300.
    View in: PubMed
  54. Chitnis T, Guttmann CR, Zaitsev A, Musallam A, Weinstock-Guttman B, Yeh A, Rodriguez M, Ness J, Gorman MP, Healy BC, Kuntz N, Chabas D, Strober JB, Waubant E, Krupp L, Pelletier D, Erickson B, Bergsland N, Zivadinov R. Quantitative MRI analysis in children with multiple sclerosis: a multicenter feasibility pilot study. BMC Neurol. 2013 Nov 13; 13:173. PMID: 24225378; PMCID: PMC3832402.
    View in: PubMed, PubMed Central
  55. Messina S, Vargas-Lowy D, Musallam A, Healy BC, Kivisakk P, Gandhi R, Bove R, Gholipour T, Khoury S, Weiner HL, Chitnis T. Increased leptin and A-FABP levels in relapsing and progressive forms of MS. BMC Neurol. 2013 Nov 11; 13:172. PMID: 24215402; PMCID: PMC3829106.
    View in: PubMed, PubMed Central
  56. Carruthers RL, Chitnis T, Healy BC. Modeling probability of additional cases of natalizumab-associated JCV sero-negative progressive multifocal leukoencephalopathy. Mult Scler. 2014 May; 20(6):757-60. PMID: 24189572.
    View in: PubMed
  57. Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL. Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus. Neurology. 2013 Nov 26; 81(22):1891-9. PMID: 24174586; PMCID: PMC3843384.
    View in: PubMed, PubMed Central
  58. Huffman JC, DuBois CM, Healy BC, Boehm JK, Kashdan TB, Celano CM, Denninger JW, Lyubomirsky S. Feasibility and utility of positive psychology exercises for suicidal inpatients. Gen Hosp Psychiatry. 2014 Jan-Feb; 36(1):88-94. PMID: 24230461.
    View in: PubMed
  59. Kivisäkk P, Healy BC, Francois K, Gandhi R, Gholipour T, Egorova S, Sevdalinova V, Quintana F, Chitnis T, Weiner HL, Khoury SJ. Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: relevance for biomarker development. Mult Scler. 2014 Apr; 20(4):438-44. PMID: 24005026.
    View in: PubMed
  60. Minden SL, Ding L, Cleary PD, Frankel D, Glanz BI, Healy BC, Rintell DJ. Improving the quality of mental health care in multiple sclerosis. J Neurol Sci. 2013 Dec 15; 335(1-2):42-7. PMID: 24183855.
    View in: PubMed
  61. Beach SR, Januzzi JL, Mastromauro CA, Healy BC, Beale EE, Celano CM, Huffman JC. Patient Health Questionnaire-9 score and adverse cardiac outcomes in patients hospitalized for acute cardiac disease. J Psychosom Res. 2013 Nov; 75(5):409-13. PMID: 24182627.
    View in: PubMed
  62. Schwartz CE, Quaranto BR, Rapkin BD, Healy BC, Vollmer T, Sprangers MA. Fluctuations in appraisal over time in the context of stable versus non-stable health. Qual Life Res. 2014 Feb; 23(1):9-19. PMID: 23851975.
    View in: PubMed
  63. Benson LA, Healy BC, Gorman MP, Baruch NF, Gholipour T, Musallam A, Chitnis T. Elevated relapse rates in pediatric compared to adult MS persist for at least 6 years. Mult Scler Relat Disord. 2014 Mar; 3(2):186-93. PMID: 25878006.
    View in: PubMed
  64. Gandhi R, Healy B, Gholipour T, Egorova S, Musallam A, Hussain MS, Nejad P, Patel B, Hei H, Khoury S, Quintana F, Kivisakk P, Chitnis T, Weiner HL. Circulating microRNAs as biomarkers for disease staging in multiple sclerosis. Ann Neurol. 2013 Jun; 73(6):729-40. PMID: 23494648.
    View in: PubMed
  65. Bove R, Musallam A, Healy BC, Houtchens M, Glanz BI, Khoury S, Guttmann CR, De Jager PL, Chitnis T. No sex-specific difference in disease trajectory in multiple sclerosis patients before and after age 50. BMC Neurol. 2013 Jul 03; 13:73. PMID: 23822612; PMCID: PMC3707791.
    View in: PubMed, PubMed Central
  66. Schwartz CE, Quaranto BR, Healy BC, Benedict RH, Vollmer TL. Cognitive reserve and symptom experience in multiple sclerosis: a buffer to disability progression over time? Arch Phys Med Rehabil. 2013 Oct; 94(10):1971-81. PMID: 23727344.
    View in: PubMed
  67. Bove RM, Brick DJ, Healy BC, Mancuso SM, Gerweck AV, Bredella MA, Sherman JC, Miller KK. Metabolic and endocrine correlates of cognitive function in healthy young women. Obesity (Silver Spring). 2013 Jul; 21(7):1343-9. PMID: 23671055; PMCID: PMC3742554.
    View in: PubMed, PubMed Central
  68. Healy BC, Schoenfeld D. Reply: To PMID 22987690. Muscle Nerve. 2013 May; 47(5):779-80. PMID: 23536327.
    View in: PubMed
  69. Bove R, Secor E, Healy BC, Musallam A, Vaughan T, Glanz BI, Greeke E, Weiner HL, Chitnis T, Wicks P, De Jager PL. Evaluation of an online platform for multiple sclerosis research: patient description, validation of severity scale, and exploration of BMI effects on disease course. PLoS One. 2013; 8(3):e59707. PMID: 23527256; PMCID: PMC3603866.
    View in: PubMed, PubMed Central
  70. Benedict RH, Schwartz CE, Duberstein P, Healy B, Hoogs M, Bergsland N, Dwyer MG, Weinstock-Guttman B, Zivadinov R. Influence of personality on the relationship between gray matter volume and neuropsychiatric symptoms in multiple sclerosis. Psychosom Med. 2013 Apr; 75(3):253-61. PMID: 23504242.
    View in: PubMed
  71. Healy BC, Engler D, Glanz B, Musallam A, Chitnis T. Assessment of definitions of sustained disease progression in relapsing-remitting multiple sclerosis. Mult Scler Int. 2013; 2013:189624. PMID: 23555057; PMCID: PMC3608311.
    View in: PubMed, PubMed Central
  72. Glanz BI, Dégano IR, Rintell DJ, Chitnis T, Weiner HL, Healy BC. Work productivity in relapsing multiple sclerosis: associations with disability, depression, fatigue, anxiety, cognition, and health-related quality of life. Value Health. 2012 Dec; 15(8):1029-35. PMID: 23244804.
    View in: PubMed
  73. Healy BC, Schoenfeld D. Comparison of analysis approaches for phase III clinical trials in amyotrophic lateral sclerosis. Muscle Nerve. 2012 Oct; 46(4):506-11. PMID: 22987690.
    View in: PubMed
  74. Vishwas MS, Healy BC, Pienaar R, Gorman MP, Grant PE, Chitnis T. Diffusion tensor analysis of pediatric multiple sclerosis and clinically isolated syndromes. AJNR Am J Neuroradiol. 2013 Feb; 34(2):417-23. PMID: 22859275.
    View in: PubMed
  75. Bove RM, Healy B, Augustine A, Musallam A, Gholipour T, Chitnis T. Effect of gender on late-onset multiple sclerosis. Mult Scler. 2012 Oct; 18(10):1472-9. PMID: 22383227.
    View in: PubMed
  76. Healy BC, Degano IR, Schreck A, Rintell D, Weiner H, Chitnis T, Glanz BI. The impact of a recent relapse on patient-reported outcomes in subjects with multiple sclerosis. Qual Life Res. 2012 Dec; 21(10):1677-84. PMID: 22237991.
    View in: PubMed
  77. Moodie J, Healy BC, Buckle GJ, Gauthier SA, Glanz BI, Arora A, Ceccarelli A, Tauhid S, Han XM, Venkataraman A, Chitnis T, Khoury SJ, Guttmann CR, Weiner HL, Neema M, Bakshi R. Magnetic resonance disease severity scale (MRDSS) for patients with multiple sclerosis: a longitudinal study. J Neurol Sci. 2012 Apr 15; 315(1-2):49-54. PMID: 22209496; PMCID: PMC3319060.
    View in: PubMed, PubMed Central
  78. Healy BC, Arora A, Hayden DL, Ceccarelli A, Tauhid SS, Neema M, Bakshi R. Approaches to normalization of spinal cord volume: application to multiple sclerosis. J Neuroimaging. 2012 Jul; 22(3):e12-9. PMID: 21854479; PMCID: PMC3290735.
    View in: PubMed, PubMed Central
  79. Glanz BI, Healy BC, Hviid LE, Chitnis T, Weiner HL. Cognitive deterioration in patients with early multiple sclerosis: a 5-year study. J Neurol Neurosurg Psychiatry. 2012 Jan; 83(1):38-43. PMID: 21746743.
    View in: PubMed
  80. Gholipour T, Healy B, Baruch NF, Weiner HL, Chitnis T. Demographic and clinical characteristics of malignant multiple sclerosis. Neurology. 2011 Jun 07; 76(23):1996-2001. PMID: 21646626.
    View in: PubMed
  81. Klein JP, Arora A, Neema M, Healy BC, Tauhid S, Goldberg-Zimring D, Chavarro-Nieto C, Stankiewicz JM, Cohen AB, Buckle GJ, Houtchens MK, Ceccarelli A, Dell'Oglio E, Guttmann CR, Alsop DC, Hackney DB, Bakshi R. A 3T MR imaging investigation of the topography of whole spinal cord atrophy in multiple sclerosis. AJNR Am J Neuroradiol. 2011 Jun-Jul; 32(6):1138-42. PMID: 21527570; PMCID: PMC3361764.
    View in: PubMed, PubMed Central
  82. Healy B, Chitnis T, Engler D. Improving power to detect disease progression in multiple sclerosis through alternative analysis strategies. J Neurol. 2011 Oct; 258(10):1812-9. PMID: 21472497.
    View in: PubMed
  83. Stankiewicz JM, Glanz BI, Healy BC, Arora A, Neema M, Benedict RH, Guss ZD, Tauhid S, Buckle GJ, Houtchens MK, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Brain MRI lesion load at 1.5T and 3T versus clinical status in multiple sclerosis. J Neuroimaging. 2011 Apr; 21(2):e50-6. PMID: 19888926; PMCID: PMC3043123.
    View in: PubMed, PubMed Central
  84. Liguori M, Meier DS, Hildenbrand P, Healy BC, Chitnis T, Baruch NF, Khoury SJ, Weiner HL, Bakshi R, Barkhof F, Guttmann CR. One year activity on subtraction MRI predicts subsequent 4 year activity and progression in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2011 Oct; 82(10):1125-31. PMID: 21429902.
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  85. Huffman JC, Mastromauro CA, Sowden G, Fricchione GL, Healy BC, Januzzi JL. Impact of a depression care management program for hospitalized cardiac patients. Circ Cardiovasc Qual Outcomes. 2011 Mar; 4(2):198-205. PMID: 21386067.
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  86. Hviid LE, Healy BC, Rintell DJ, Chitnis T, Weiner HL, Glanz BI. Patient reported outcomes in benign multiple sclerosis. Mult Scler. 2011 Jul; 17(7):876-84. PMID: 21372114.
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  87. Mike A, Glanz BI, Hildenbrand P, Meier D, Bolden K, Liguori M, Dell'Oglio E, Healy BC, Bakshi R, Guttmann CR. Identification and clinical impact of multiple sclerosis cortical lesions as assessed by routine 3T MR imaging. AJNR Am J Neuroradiol. 2011 Mar; 32(3):515-21. PMID: 21310857.
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  88. Healy BC, Engler D, Gholipour T, Weiner H, Bakshi R, Chitnis T. Accounting for disease modifying therapy in models of clinical progression in multiple sclerosis. J Neurol Sci. 2011 Apr 15; 303(1-2):109-13. PMID: 21251671.
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  89. Liguori M, Healy BC, Glanz BI, Khoury SJ, Moscufo N, Weiner HL, De Jager PL, Guttmann CR. HLA (A-B-C and -DRB1) alleles and brain MRI changes in multiple sclerosis: a longitudinal study. Genes Immun. 2011 Apr; 12(3):183-90. PMID: 21179117.
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  90. Gross R, Healy BC, Cepok S, Chitnis T, Khoury SJ, Hemmer B, Weiner HL, Hafler DA, De Jager PL. Population structure and HLA DRB1 1501 in the response of subjects with multiple sclerosis to first-line treatments. J Neuroimmunol. 2011 Apr; 233(1-2):168-74. PMID: 21115201.
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  91. Xiao D, Cassin JJ, Healy B, Burdett TC, Chen JF, Fredholm BB, Schwarzschild MA. Deletion of adenosine A1 or A(2A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease. Brain Res. 2011 Jan 07; 1367:310-8. PMID: 20828543; PMCID: PMC3005012.
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  92. Khoury SJ, Healy BC, Kivisäkk P, Viglietta V, Egorova S, Guttmann CR, Wedgwood JF, Hafler DA, Weiner HL, Buckle G, Cook S, Reddy S. A randomized controlled double-masked trial of albuterol add-on therapy in patients with multiple sclerosis. Arch Neurol. 2010 Sep; 67(9):1055-61. PMID: 20837847; PMCID: PMC2954052.
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  93. Meier DS, Balashov KE, Healy B, Weiner HL, Guttmann CR. Seasonal prevalence of MS disease activity. Neurology. 2010 Aug 31; 75(9):799-806. PMID: 20805526; PMCID: PMC2938966.
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  94. Healy BC, Glanz BI, Stankiewicz J, Buckle G, Weiner H, Chitnis T. A method for evaluating treatment switching criteria in multiple sclerosis. Mult Scler. 2010 Dec; 16(12):1483-9. PMID: 20736245.
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  95. Healy BC, Liguori M, Tran D, Chitnis T, Glanz B, Wolfish C, Gauthier S, Buckle G, Houtchens M, Stazzone L, Khoury S, Hartzmann R, Fernandez-Vina M, Hafler DA, Weiner HL, Guttmann CR, De Jager PL. HLA B*44: protective effects in MS susceptibility and MRI outcome measures. Neurology. 2010 Aug 17; 75(7):634-40. PMID: 20713950; PMCID: PMC2931768.
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  96. Healy BC, Ikle D, Macklin EA, Cutter G. Optimal design and analysis of phase I/II clinical trials in multiple sclerosis with gadolinium-enhanced lesions as the endpoint. Mult Scler. 2010 Jul; 16(7):840-7. PMID: 20530124.
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  97. Healy B, Beasley R, Weatherall M. Venous thromboembolism following prolonged cast immobilisation for injury to the tendo Achillis. J Bone Joint Surg Br. 2010 May; 92(5):646-50. PMID: 20436000.
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  98. Sampat MP, Healy BC, Meier DS, Dell'Oglio E, Liguori M, Guttmann CR. Disease modeling in multiple sclerosis: assessment and quantification of sources of variability in brain parenchymal fraction measurements. Neuroimage. 2010 Oct 01; 52(4):1367-73. PMID: 20362675.
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  99. Wijesinghe M, Perrin K, Healy B, Hart K, Clay J, Weatherall M, Beasley R. Pre-hospital oxygen therapy in acute exacerbations of chronic obstructive pulmonary disease. Intern Med J. 2011 Aug; 41(8):618-22. PMID: 20214690.
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  100. Glanz BI, Healy BC, Rintell DJ, Jaffin SK, Bakshi R, Weiner HL. The association between cognitive impairment and quality of life in patients with early multiple sclerosis. J Neurol Sci. 2010 Mar 15; 290(1-2):75-9. PMID: 19944429.
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  101. Vishwas MS, Chitnis T, Pienaar R, Healy BC, Grant PE. Tract-based analysis of callosal, projection, and association pathways in pediatric patients with multiple sclerosis: a preliminary study. AJNR Am J Neuroradiol. 2010 Jan; 31(1):121-8. PMID: 19850763.
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  102. Sampat MP, Berger AM, Healy BC, Hildenbrand P, Vass J, Meier DS, Chitnis T, Weiner HL, Bakshi R, Guttmann CR. Regional white matter atrophy--based classification of multiple sclerosis in cross-sectional and longitudinal data. AJNR Am J Neuroradiol. 2009 Oct; 30(9):1731-9. PMID: 19696139; PMCID: PMC2821733.
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  103. Healy BC, Ali EN, Guttmann CR, Chitnis T, Glanz BI, Buckle G, Houtchens M, Stazzone L, Moodie J, Berger AM, Duan Y, Bakshi R, Khoury S, Weiner H, Ascherio A. Smoking and disease progression in multiple sclerosis. Arch Neurol. 2009 Jul; 66(7):858-64. PMID: 19597087; PMCID: PMC2754172.
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  104. Kivisäkk P, Healy BC, Viglietta V, Quintana FJ, Hootstein MA, Weiner HL, Khoury SJ. Natalizumab treatment is associated with peripheral sequestration of proinflammatory T cells. Neurology. 2009 Jun 02; 72(22):1922-30. PMID: 19487650; PMCID: PMC2690969.
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  105. Ceccarelli A, Filippi M, Neema M, Arora A, Valsasina P, Rocca MA, Healy BC, Bakshi R. T2 hypointensity in the deep gray matter of patients with benign multiple sclerosis. Mult Scler. 2009 Jun; 15(6):678-86. PMID: 19482861.
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  106. Moscufo N, Guttmann CR, Meier D, Csapo I, Hildenbrand PG, Healy BC, Schmidt JA, Wolfson L. Brain regional lesion burden and impaired mobility in the elderly. Neurobiol Aging. 2011 Apr; 32(4):646-54. PMID: 19428145; PMCID: PMC2942957.
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  107. Healy BC, Engler D. Modeling disease-state transition heterogeneity through Bayesian variable selection. Stat Med. 2009 Apr 30; 28(9):1353-68. PMID: 19206077.
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  108. Neema M, Guss ZD, Stankiewicz JM, Arora A, Healy BC, Bakshi R. Normal findings on brain fluid-attenuated inversion recovery MR images at 3T. AJNR Am J Neuroradiol. 2009 May; 30(5):911-6. PMID: 19369605; PMCID: PMC3003332.
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  109. Stankiewicz JM, Neema M, Alsop DC, Healy BC, Arora A, Buckle GJ, Chitnis T, Guttmann CR, Hackney D, Bakshi R. Spinal cord lesions and clinical status in multiple sclerosis: A 1.5 T and 3 T MRI study. J Neurol Sci. 2009 Apr 15; 279(1-2):99-105. PMID: 19178916; PMCID: PMC2679653.
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  110. Chitnis T, Glanz B, Jaffin S, Healy B. Demographics of pediatric-onset multiple sclerosis in an MS center population from the Northeastern United States. Mult Scler. 2009 May; 15(5):627-31. PMID: 19299440.
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  111. Neema M, Goldberg-Zimring D, Guss ZD, Healy BC, Guttmann CR, Houtchens MK, Weiner HL, Horsfield MA, Hackney DB, Alsop DC, Bakshi R. 3 T MRI relaxometry detects T2 prolongation in the cerebral normal-appearing white matter in multiple sclerosis. Neuroimage. 2009 Jul 01; 46(3):633-41. PMID: 19281850; PMCID: PMC2974316.
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  112. Healy B, Valsasina P, Filippi M, Bakshi R. Sample size requirements for treatment effects using gray matter, white matter and whole brain volume in relapsing-remitting multiple sclerosis. J Neurol Neurosurg Psychiatry. 2009 Nov; 80(11):1218-23. PMID: 19204021; PMCID: PMC2846617.
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  113. Maier LM, Anderson DE, Severson CA, Baecher-Allan C, Healy B, Liu DV, Wittrup KD, De Jager PL, Hafler DA. Soluble IL-2RA levels in multiple sclerosis subjects and the effect of soluble IL-2RA on immune responses. J Immunol. 2009 Feb 01; 182(3):1541-7. PMID: 19155502; PMCID: PMC3992946.
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  114. Ali EN, Healy BC, Stazzone LA, Brown BA, Weiner HL, Khoury SJ. Daclizumab in treatment of multiple sclerosis patients. Mult Scler. 2009 Feb; 15(2):272-4. PMID: 19136546.
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  115. Healy BC, Hayden DL, Sampat MP, Bakshi R, Guttmann CR. Unbiased treatment effect estimates by modeling the disease process of multiple sclerosis. J Neurol Sci. 2009 Mar 15; 278(1-2):54-9. PMID: 19121526.
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  116. Gorman MP, Healy BC, Polgar-Turcsanyi M, Chitnis T. Increased relapse rate in pediatric-onset compared with adult-onset multiple sclerosis. Arch Neurol. 2009 Jan; 66(1):54-9. PMID: 19139299.
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  117. Neema M, Arora A, Healy BC, Guss ZD, Brass SD, Duan Y, Buckle GJ, Glanz BI, Stazzone L, Khoury SJ, Weiner HL, Guttmann CR, Bakshi R. Deep gray matter involvement on brain MRI scans is associated with clinical progression in multiple sclerosis. J Neuroimaging. 2009 Jan; 19(1):3-8. PMID: 19192042; PMCID: PMC2762230.
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  118. Barnes RA, White PL, Bygrave C, Evans N, Healy B, Kell J. Clinical impact of enhanced diagnosis of invasive fungal disease in high-risk haematology and stem cell transplant patients. J Clin Pathol. 2009 Jan; 62(1):64-9. PMID: 19103864.
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  119. Bakshi R, Neema M, Healy BC, Liptak Z, Betensky RA, Buckle GJ, Gauthier SA, Stankiewicz J, Meier D, Egorova S, Arora A, Guss ZD, Glanz B, Khoury SJ, Guttmann CR, Weiner HL. Predicting clinical progression in multiple sclerosis with the magnetic resonance disease severity scale. Arch Neurol. 2008 Nov; 65(11):1449-53. PMID: 19001162; PMCID: PMC2762216.
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  120. Viglietta V, Bourcier K, Buckle GJ, Healy B, Weiner HL, Hafler DA, Egorova S, Guttmann CR, Rusche JR, Khoury SJ. CTLA4Ig treatment in patients with multiple sclerosis: an open-label, phase 1 clinical trial. Neurology. 2008 Sep 16; 71(12):917-24. PMID: 18794494.
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  121. Liptak Z, Berger AM, Sampat MP, Charil A, Felsovalyi O, Healy BC, Hildenbrand P, Khoury SJ, Weiner HL, Bakshi R, Guttmann CR. Medulla oblongata volume: a biomarker of spinal cord damage and disability in multiple sclerosis. AJNR Am J Neuroradiol. 2008 Sep; 29(8):1465-70. PMID: 18556361.
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  122. Healy BC, DeGruttola VG, Hu C. Accommodating uncertainty in a tree set for function estimation. Stat Appl Genet Mol Biol. 2008; 7(1):Article5. PMID: 18312210.
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  123. Rodríguez JR, Madanat MG, Healy BC, Thayer SP, Warshaw AL, Fernández-del Castillo C. Distal pancreatectomy with splenic preservation revisited. Surgery. 2007 May; 141(5):619-25. PMID: 17462461; PMCID: PMC3807103.
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  124. Healy B, De Gruttola V, Pagano M. Combining cross-sectional and prospective data methods to improve transition parameter estimation for characterizing the accumulation of HIV-1 drug resistance mutations. Biometrics. 2007 Sep; 63(3):742-50. PMID: 17403101.
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  125. Healy B, Degruttola V. Hidden Markov models for settings with interval-censored transition times and uncertain time origin: application to HIV genetic analyses. Biostatistics. 2007 Apr; 8(2):438-52. PMID: 16940036.
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  126. Abdel-Wahab OI, Healy B, Dzik WH. Effect of fresh-frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalities. Transfusion. 2006 Aug; 46(8):1279-85. PMID: 16934060.
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  127. Healy B, Thadani R. Preserving America's spirit. Transfusion. 2001 Oct; 41(10):1185. PMID: 11606812.
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  128. Urata H, Healy B, Stewart RW, Bumpus FM, Husain A. Angiotensin II receptors in normal and failing human hearts. J Clin Endocrinol Metab. 1989 Jul; 69(1):54-66. PMID: 2732298.
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