"Vaccines, Conjugate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection.
MeSH Number(s)
D20.215.894.865.900
D23.050.865.900
Below are MeSH descriptors whose meaning is more general than "Vaccines, Conjugate".
Below are MeSH descriptors whose meaning is more specific than "Vaccines, Conjugate".
This graph shows the total number of publications written about "Vaccines, Conjugate" by people in Harvard Catalyst Profiles by year, and whether "Vaccines, Conjugate" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 2 | 2 |
| 1994 | 0 | 3 | 3 |
| 1995 | 1 | 2 | 3 |
| 1996 | 2 | 4 | 6 |
| 1997 | 2 | 2 | 4 |
| 1998 | 1 | 2 | 3 |
| 1999 | 5 | 5 | 10 |
| 2000 | 0 | 2 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 1 | 4 | 5 |
| 2003 | 3 | 1 | 4 |
| 2004 | 2 | 3 | 5 |
| 2005 | 1 | 7 | 8 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 3 | 4 |
| 2008 | 2 | 2 | 4 |
| 2009 | 2 | 3 | 5 |
| 2010 | 1 | 4 | 5 |
| 2011 | 1 | 4 | 5 |
| 2012 | 3 | 5 | 8 |
| 2013 | 1 | 7 | 8 |
| 2014 | 3 | 4 | 7 |
| 2015 | 5 | 9 | 14 |
| 2016 | 3 | 2 | 5 |
| 2017 | 3 | 7 | 10 |
| 2018 | 5 | 7 | 12 |
| 2019 | 1 | 8 | 9 |
| 2020 | 2 | 11 | 13 |
| 2021 | 1 | 6 | 7 |
| 2022 | 0 | 12 | 12 |
| 2023 | 0 | 5 | 5 |
Below are the most recent publications written about "Vaccines, Conjugate" by people in Profiles.
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Vaccination of Rabbits with a Cholera Conjugate Vaccine Comprising O-Specific Polysaccharide and a Recombinant Fragment of Tetanus Toxin Heavy Chain Induces Protective Immune Responses against Vibrio cholerae O1. Am J Trop Med Hyg. 2023 11 01; 109(5):1122-1128.
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Health Care Provider Knowledge and Attitudes Regarding Adult Pneumococcal Conjugate Vaccine Recommendations - United States, September 28-October 10, 2022. MMWR Morb Mortal Wkly Rep. 2023 Sep 08; 72(36):979-984.
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Immunogenicity of quadrivalent meningococcal conjugate vaccine in frequent platelet donors. Blood. 2023 Jul 13; 142(2):202-209.
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Using LASSO Regression to Estimate the Population-Level Impact of Pneumococcal Conjugate Vaccines. Am J Epidemiol. 2023 Jul 07; 192(7):1166-1180.
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Development of Shigella conjugate vaccines targeting Shigella flexneri 2a and S. flexneri 3a using a simple platform-approach conjugation by squaric acid chemistry. Vaccine. 2023 07 31; 41(34):4967-4977.
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Acute otitis media pneumococcal disease burden and nasopharyngeal colonization in children due to serotypes included and not included in current and new pneumococcal conjugate vaccines. Expert Rev Vaccines. 2023 Jan-Dec; 22(1):118-138.
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Effectiveness of 13-valent pneumococcal conjugate vaccine on radiological primary end-point pneumonia among cases of severe community acquired pneumonia in children: A prospective multi-site hospital-based test-negative study in Northern India. PLoS One. 2022; 17(12):e0276911.
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Immunogenicity of three versus four doses of 13-valent pneumococcal conjugate vaccine followed by 23-valent pneumococcal polysaccharide vaccine in allogeneic haematopoietic stem cell transplantation recipients: a multicentre, randomized controlled trial. Clin Microbiol Infect. 2023 Apr; 29(4):482-489.
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Characteristics of endovascular pneumococcal infections; a decade of nationwide surveillance study. Eur J Clin Microbiol Infect Dis. 2022 Nov; 41(11):1365-1370.
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Effect of Maternal Immunization With 10-Valent Pneumococcus Conjugate Vaccine (PCV-10), 23-Valent Pneumococcus Polysaccharide Vaccine, or Placebo on the Immunogenicity of PCV-10 in Human Immunodeficiency Virus-Exposed Uninfected Infants: A Randomized Clinical Trial. Clin Infect Dis. 2022 09 29; 75(6):996-1005.