Tunicamycin

"Tunicamycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi, because it inhibits the glucosylation of proteins. Tunicamycin is used as tool in the study of microbial biosynthetic mechanisms.

Descriptor ID

D014415

MeSH Number(s)

D03.383.742.680.725

D13.570.685.725

Concept/Terms

Tunicamycin

Below are MeSH descriptors whose meaning is more general than "Tunicamycin".

Chemicals and Drugs [D]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, 1-Ring [D03.383]
Pyrimidines [D03.383.742]
Pyrimidine Nucleosides [D03.383.742.680]
Tunicamycin [D03.383.742.680.725]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleosides [D13.570]
Pyrimidine Nucleosides [D13.570.685]
Tunicamycin [D13.570.685.725]

Below are MeSH descriptors whose meaning is related to "Tunicamycin".

Below are MeSH descriptors whose meaning is more specific than "Tunicamycin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Tunicamycin" by people in Harvard Catalyst Profiles by year, and whether "Tunicamycin" was a major or minor topic of these publication.

Bar chart showing 61 publications over 25 distinct years, with a maximum of 6 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	1	1
1995	1	3	4
1996	0	2	2
1997	0	2	2
1998	0	1	1
2000	0	1	1
2001	0	1	1
2002	0	1	1
2003	0	3	3
2004	0	3	3
2005	0	1	1
2006	0	3	3
2008	1	1	2
2009	0	4	4
2010	0	4	4
2011	0	5	5
2013	0	3	3
2014	0	2	2
2015	1	1	2
2016	2	4	6
2017	0	1	1
2018	0	2	2
2019	2	1	3
2021	1	2	3
2023	0	1	1

Below are the most recent publications written about "Tunicamycin" by people in Profiles.

CRISPR-Cas9 genetic screen leads to the discovery of L-Moses, a KAT2B inhibitor that attenuates Tunicamycin-mediated neuronal cell death. Sci Rep. 2023 03 09; 13(1):3934.

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Structural and Functional Analysis of Female Sex Hormones against SARS-CoV-2 Cell Entry. Int J Mol Sci. 2021 Oct 26; 22(21).

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Gut bacterial metabolites modulate endoplasmic reticulum stress. Genome Biol. 2021 10 15; 22(1):292.

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NHR-8 and P-glycoproteins uncouple xenobiotic resistance from longevity in chemosensory C. elegans mutants. Elife. 2021 08 27; 10.

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Nucleotide-binding oligomerization domain protein 2 attenuates ER stress-induced cell death in vascular smooth muscle cells. BMB Rep. 2019 Nov; 52(11):665-670.

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Tet38 of Staphylococcus aureus Binds to Host Cell Receptor Complex CD36-Toll-Like Receptor 2 and Protects from Teichoic Acid Synthesis Inhibitors Tunicamycin and Congo Red. Infect Immun. 2019 07; 87(7).

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Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress. Cell Death Dis. 2019 02 15; 10(3):155.

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Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans. Genetics. 2018 12; 210(4):1329-1337.

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Genetic screen identifies adaptive aneuploidy as a key mediator of ER stress resistance in yeast. Proc Natl Acad Sci U S A. 2018 09 18; 115(38):9586-9591.

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Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A. 2018 08 07; 115(32):8209-8214.

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