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Tumor Necrosis Factor-alpha

"Tumor Necrosis Factor-alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.


This graph shows the total number of publications written about "Tumor Necrosis Factor-alpha" by people in Harvard Catalyst Profiles by year, and whether "Tumor Necrosis Factor-alpha" was a major or minor topic of these publication.
Bar chart showing 2831 publications over 31 distinct years, with a maximum of 123 publications in 2012
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.