"Transglutaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transglutaminases catalyze cross-linking of proteins at a GLUTAMINE in one chain with LYSINE in another chain. They include keratinocyte transglutaminase (TGM1 or TGK), tissue transglutaminase (TGM2 or TGC), plasma transglutaminase involved with coagulation (FACTOR XIII and FACTOR XIIIa), hair follicle transglutaminase, and prostate transglutaminase. Although structures differ, they share an active site (YGQCW) and strict CALCIUM dependence.
Concept/Terms
Transglutaminases- Transglutaminases
- Glutaminyl-Peptide Gamma-Glutamyltransferases
- Gamma-Glutamyltransferases, Glutaminyl-Peptide
- Glutaminyl Peptide Gamma Glutamyltransferases
- Protein-Glutamine gamma-Glutamyltransferases
- Protein Glutamine gamma Glutamyltransferases
- gamma-Glutamyltransferases, Protein-Glutamine
Below are MeSH descriptors whose meaning is more general than "Transglutaminases".
Below are MeSH descriptors whose meaning is more specific than "Transglutaminases".
This graph shows the total number of publications written about "Transglutaminases" by people in Harvard Catalyst Profiles by year, and whether "Transglutaminases" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 2 | 2 |
| 1994 | 1 | 1 | 2 |
| 1996 | 2 | 0 | 2 |
| 1997 | 1 | 1 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 3 | 0 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 5 | 3 | 8 |
| 2007 | 0 | 1 | 1 |
| 2009 | 1 | 3 | 4 |
| 2010 | 2 | 2 | 4 |
| 2011 | 3 | 1 | 4 |
| 2012 | 4 | 6 | 10 |
| 2013 | 3 | 2 | 5 |
| 2014 | 9 | 5 | 14 |
| 2015 | 3 | 3 | 6 |
| 2016 | 8 | 6 | 14 |
| 2017 | 5 | 3 | 8 |
| 2018 | 6 | 0 | 6 |
| 2019 | 3 | 4 | 7 |
| 2020 | 3 | 1 | 4 |
| 2021 | 1 | 5 | 6 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Transglutaminases" by people in Profiles.
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Early Antibody Dynamics in a Prospective Cohort of Children At Risk of Celiac Disease. Am J Gastroenterol. 2023 03 01; 118(3):574-577.
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Systematic review with meta-analysis: the accuracy of serological tests to support the diagnosis of coeliac disease. Aliment Pharmacol Ther. 2022 03; 55(5):514-527.
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Prevalence of celiac disease in China: Meta-analysis and serological survey in high-risk populations. J Dig Dis. 2021 Nov; 22(11):645-655.
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Clinical classification and long-term outcomes of seronegative coeliac disease: a 20-year multicentre follow-up study. Aliment Pharmacol Ther. 2021 11; 54(10):1278-1289.
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Neither a Novel Tau Proteinopathy nor an Expansion of a Phenotype: Reappraising Clinicopathology-Based Nosology. Int J Mol Sci. 2021 Jul 07; 22(14).
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An Unusual "OR" Gate for Allosteric Regulation of Mammalian Transglutaminase 2 in the Extracellular Matrix. J Am Chem Soc. 2021 07 21; 143(28):10537-10540.
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What is the Optimal Method Assessing for Persistent Villous Atrophy in Adult Coeliac Disease? J Gastrointestin Liver Dis. 2021 06 18; 30(2):205-212.
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Estimating the Impact of Verification Bias on Celiac Disease Testing. J Clin Gastroenterol. 2021 04 01; 55(4):327-334.
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Seroprevalence of Antitransglutaminase and Antiendomysium Antibodies in Adult Colombian Blood Bank Donors. Can J Gastroenterol Hepatol. 2020; 2020:7541941.
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The Utility of IgA-Based Serologic Markers in Diagnosing Celiac Disease in Children 24 Months of Age or Younger. J Pediatr. 2020 09; 224:158-161.e2.