Harvard Catalyst Profiles

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Transforming Growth Factor beta1

"Transforming Growth Factor beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A subtype of transforming growth factor beta that is synthesized by a wide variety of cells. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta 1 and TGF-beta1 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor. Defects in the gene that encodes TGF-beta1 are the cause of CAMURATI-ENGELMANN SYNDROME.


This graph shows the total number of publications written about "Transforming Growth Factor beta1" by people in Harvard Catalyst Profiles by year, and whether "Transforming Growth Factor beta1" was a major or minor topic of these publication.
Bar chart showing 374 publications over 20 distinct years, with a maximum of 31 publications in 2012
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.