Harvard Catalyst Profiles

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Tissue Plasminogen Activator

"Tissue Plasminogen Activator" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.


This graph shows the total number of publications written about "Tissue Plasminogen Activator" by people in Harvard Catalyst Profiles by year, and whether "Tissue Plasminogen Activator" was a major or minor topic of these publication.
Bar chart showing 636 publications over 30 distinct years, with a maximum of 39 publications in 2017
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.