"Theobromine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
MeSH Number(s)
D03.132.960.651
D03.438.759.758.824.651
Below are MeSH descriptors whose meaning is more general than "Theobromine".
Below are MeSH descriptors whose meaning is more specific than "Theobromine".
This graph shows the total number of publications written about "Theobromine" by people in Harvard Catalyst Profiles by year, and whether "Theobromine" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2009 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
Below are the most recent publications written about "Theobromine" by people in Profiles.
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Preconception caffeine metabolites, caffeinated beverage intake, and fecundability. Am J Clin Nutr. 2022 Apr 01; 115(4):1227-1236.
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Maternal caffeine intake and DNA methylation in newborn cord blood. Am J Clin Nutr. 2022 02 09; 115(2):482-491.
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Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. Hum Mol Genet. 2016 12 15; 25(24):5472-5482.
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Cocoa bioactive compounds: significance and potential for the maintenance of skin health. Nutrients. 2014 Aug 11; 6(8):3202-13.
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Cocoa phytochemicals: recent advances in molecular mechanisms on health. Crit Rev Food Sci Nutr. 2014; 54(11):1458-72.
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Effects of theobromine and caffeine on mood and vigilance. J Clin Psychopharmacol. 2013 Aug; 33(4):499-506.
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Quantification of theobromine and caffeine in saliva, plasma and urine via liquid chromatography-tandem mass spectrometry: a single analytical protocol applicable to cocoa intervention studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Feb 01; 878(3-4):409-16.
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A theobromine derived silver N-heterocyclic carbene: synthesis, characterization, and antimicrobial efficacy studies on cystic fibrosis relevant pathogens. Dalton Trans. 2009 Sep 21; (35):7308-13.
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The role of the basal forebrain adenosine receptors in sleep homeostasis. Neuroreport. 2009 Jul 15; 20(11):1013-8.
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Chemical and archaeological evidence for the earliest cacao beverages. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):18937-40.