Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Thalidomide

"Thalidomide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppresive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.


This graph shows the total number of publications written about "Thalidomide" by people in Harvard Catalyst Profiles by year, and whether "Thalidomide" was a major or minor topic of these publication.
Bar chart showing 380 publications over 25 distinct years, with a maximum of 33 publications in 2015
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.