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Succinate-Semialdehyde Dehydrogenase

"Succinate-Semialdehyde Dehydrogenase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An enzyme that plays a role in the GLUTAMATE and butanoate metabolism pathways by catalyzing the oxidation of succinate semialdehyde to SUCCINATE using NAD+ as a coenzyme. Deficiency of this enzyme, causes 4-hydroxybutyricaciduria, a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA).

This graph shows the total number of publications written about "Succinate-Semialdehyde Dehydrogenase" by people in Harvard Catalyst Profiles by year, and whether "Succinate-Semialdehyde Dehydrogenase" was a major or minor topic of these publication.
Bar chart showing 46 publications over 21 distinct years, with a maximum of 8 publications in 2021
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.