Harvard Catalyst Profiles

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Subacute Sclerosing Panencephalitis

"Subacute Sclerosing Panencephalitis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)


This graph shows the total number of publications written about "Subacute Sclerosing Panencephalitis" by people in Harvard Catalyst Profiles by year, and whether "Subacute Sclerosing Panencephalitis" was a major or minor topic of these publication.
Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 1989 and 1997 and 1999 and 2007 and 2011 and 2015
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.