Harvard Catalyst Profiles

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Subacute Sclerosing Panencephalitis

"Subacute Sclerosing Panencephalitis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)


This graph shows the total number of publications written about "Subacute Sclerosing Panencephalitis" by people in Harvard Catalyst Profiles by year, and whether "Subacute Sclerosing Panencephalitis" was a major or minor topic of these publication.
Bar chart showing 14 publications over 10 distinct years, with a maximum of 2 publications in 2002 and 2006 and 2007 and 2008
To see the data from this visualization as text, click here.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.