Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Spironolactone

"Spironolactone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p827)


This graph shows the total number of publications written about "Spironolactone" by people in Harvard Catalyst Profiles by year, and whether "Spironolactone" was a major or minor topic of these publication.
Bar chart showing 128 publications over 25 distinct years, with a maximum of 12 publications in 2018
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.