Spectrometry, Mass, Secondary Ion
"Spectrometry, Mass, Secondary Ion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass-spectrometric technique that is used for microscopic chemical analysis. A beam of primary ions with an energy of 5-20 kiloelectronvolts (keV) bombards a small spot on the surface of the sample under ultra-high vacuum conditions. Positive and negative secondary ions sputtered from the surface are analyzed in a mass spectrometer in regards to their mass-to-charge ratio. Digital imaging can be generated from the secondary ion beams and their intensity can be measured. Ionic images can be correlated with images from light or other microscopy providing useful tools in the study of molecular and drug actions.
Concept/Terms
Spectrometry, Mass, Secondary Ion- Spectrometry, Mass, Secondary Ion
- Secondary Ion Mass Spectroscopy Microscopy
- Mass Spectrometry, Secondary Ion
- Secondary Ion Mass Spectrometry
- SIMS Microscopy
- Secondary Ion Mass Spectroscopy
- Mass Spectroscopy, Secondary Ion
- Spectroscopy, Mass, Secondary Ion
- Secondary Ion Mass Spectrometry Microscopy
Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Secondary Ion".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Secondary Ion".
This graph shows the total number of publications written about "Spectrometry, Mass, Secondary Ion" by people in Harvard Catalyst Profiles by year, and whether "Spectrometry, Mass, Secondary Ion" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 |
| 2007 | 1 | 2 | 3 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Spectrometry, Mass, Secondary Ion" by people in Profiles.
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Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging. Nat Commun. 2021 07 30; 12(1):4628.
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Evidence for Rhythmicity Pacemaker in the Calcification Process of Scleractinian Coral. Sci Rep. 2016 Feb 05; 6:20191.
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A contamination-insensitive probe for imaging specific biomolecules by secondary ion mass spectrometry. Chem Commun (Camb). 2015 Aug 28; 51(67):13221-4.
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Secondary-ion mass spectrometry of genetically encoded targets. Angew Chem Int Ed Engl. 2015 May 04; 54(19):5784-8.
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Correlated optical and isotopic nanoscopy. Nat Commun. 2014 Apr 10; 5:3664.
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Aceruloplasminemia: retinal histopathologic manifestations and iron-mediated melanosome degradation. Arch Ophthalmol. 2011 Nov; 129(11):1466-74.
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Polymer surface functionalities that control human embryoid body cell adhesion revealed by high throughput surface characterization of combinatorial material microarrays. Biomaterials. 2010 Dec; 31(34):8827-38.
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TOF-SIMS analysis of a 576 micropatterned copolymer array to reveal surface moieties that control wettability. Anal Chem. 2008 Jan 01; 80(1):135-42.
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Quantitative imaging of nitrogen fixation by individual bacteria within animal cells. Science. 2007 Sep 14; 317(5844):1563-6.
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Analyses of soft tissue from Tyrannosaurus rex suggest the presence of protein. Science. 2007 Apr 13; 316(5822):277-80.