Harvard Catalyst Profiles

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Sp1 Transcription Factor

"Sp1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Promoter-specific RNA polymerase II transcription factor that binds to the GC box, one of the upstream promoter elements, in mammalian cells. The binding of Sp1 is necessary for the initiation of transcription in the promoters of a variety of cellular and viral GENES.


This graph shows the total number of publications written about "Sp1 Transcription Factor" by people in Harvard Catalyst Profiles by year, and whether "Sp1 Transcription Factor" was a major or minor topic of these publication.
Bar chart showing 135 publications over 28 distinct years, with a maximum of 9 publications in 1999 and 2000 and 2002 and 2012
To see the data from this visualization as text, click here.
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.