"Seminoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)
Below are MeSH descriptors whose meaning is more general than "Seminoma".
Below are MeSH descriptors whose meaning is more specific than "Seminoma".
This graph shows the total number of publications written about "Seminoma" by people in Harvard Catalyst Profiles by year, and whether "Seminoma" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 2 | 4 |
| 1996 | 1 | 1 | 2 |
| 1997 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 2 | 1 | 3 |
| 2004 | 3 | 1 | 4 |
| 2005 | 4 | 1 | 5 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 2 | 3 |
| 2008 | 2 | 1 | 3 |
| 2009 | 1 | 2 | 3 |
| 2010 | 2 | 0 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 5 | 1 | 6 |
| 2013 | 8 | 1 | 9 |
| 2014 | 3 | 0 | 3 |
| 2015 | 3 | 2 | 5 |
| 2016 | 3 | 1 | 4 |
| 2018 | 2 | 2 | 4 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 2 | 2 | 4 |
Below are the most recent publications written about "Seminoma" by people in Profiles.
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A preliminary study investigating the detection of lymphovascular invasion in germ cell tumors of the testis with double staining for OCT4/CD34. Pathol Res Pract. 2021 Nov; 227:153637.
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Expression of the C-terminal region of the SSX protein is a useful diagnostic biomarker for spermatocytic tumour. Histopathology. 2021 Nov; 79(5):700-707.
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On the origin of germ cell neoplasia in situ: Dedifferentiation of human adult Sertoli cells in cross talk with seminoma cells in vitro. Neoplasia. 2021 07; 23(7):731-742.
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Survival and New Prognosticators in Metastatic Seminoma: Results From the IGCCCG-Update Consortium. J Clin Oncol. 2021 05 10; 39(14):1553-1562.
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Molecular signatures identified by integrating gene expression and methylation in non-seminoma and seminoma of testicular germ cell tumours. Epigenetics. 2021 Jan-Feb; 16(2):162-176.
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MicroRNA and transcription factor co-regulatory networks and subtype classification of seminoma and non-seminoma in testicular germ cell tumors. Sci Rep. 2020 01 21; 10(1):852.
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Readressing the rationale of irradiation in stage I seminoma guidelines: a critical essay. BJU Int. 2019 07; 124(1):35-39.
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Spermatocytic Seminoma: A Report of 85 Cases Emphasizing Its Morphologic Spectrum Including Some Aspects Not Widely Known. Am J Surg Pathol. 2019 01; 43(1):1-11.
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Differences in DNA methylation profiles by histologic subtype of paediatric germ cell tumours: a report from the Children's Oncology Group. Br J Cancer. 2018 10; 119(7):864-872.
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Seminoma with Neoplastic Meningitis Treated with Craniospinal Irradiation. Oncologist. 2018 11; 23(11):1385-1387.