"Scleritis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Refers to any inflammation of the sclera including episcleritis, a benign condition affecting only the episclera, which is generally short-lived and easily treated. Classic scleritis, on the other hand, affects deeper tissue and is characterized by higher rates of visual acuity loss and even mortality, particularly in necrotizing form. Its characteristic symptom is severe and general head pain. Scleritis has also been associated with systemic collagen disease. Etiology is unknown but is thought to involve a local immune response. Treatment is difficult and includes administration of anti-inflammatory and immunosuppressive agents such as corticosteroids. Inflammation of the sclera may also be secondary to inflammation of adjacent tissues, such as the conjunctiva.
Concept/Terms
Necrotizing Scleritis- Necrotizing Scleritis
- Necrotizing Scleritides
- Scleritides, Necrotizing
- Scleritis, Necrotizing
Below are MeSH descriptors whose meaning is more general than "Scleritis".
Below are MeSH descriptors whose meaning is more specific than "Scleritis".
This graph shows the total number of publications written about "Scleritis" by people in Harvard Catalyst Profiles by year, and whether "Scleritis" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 0 | 3 |
| 1994 | 3 | 0 | 3 |
| 1995 | 4 | 0 | 4 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 2 | 0 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 3 | 4 |
| 2002 | 3 | 0 | 3 |
| 2003 | 2 | 1 | 3 |
| 2004 | 2 | 0 | 2 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 4 | 0 | 4 |
| 2008 | 2 | 0 | 2 |
| 2009 | 6 | 0 | 6 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 1 | 2 | 3 |
| 2014 | 2 | 0 | 2 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 4 | 0 | 4 |
| 2019 | 2 | 1 | 3 |
| 2020 | 1 | 0 | 1 |
| 2021 | 4 | 0 | 4 |
| 2022 | 2 | 0 | 2 |
Below are the most recent publications written about "Scleritis" by people in Profiles.
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Mendelian Randomization Shows a Causal Effect of Low Vitamin D on Non-infectious Uveitis and Scleritis Risk. Am J Ophthalmol. 2022 12; 244:11-18.
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Possible Synergistic Role of Cryo-Alcohol Therapy in Infectious Scleritis-Scope and Rationale for Expanding Indications and Review of the Literature. Cornea. 2023 Feb 01; 42(2):194-203.
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Choroidal Effusions and Posterior Scleritis in Idiopathic Orbital Inflammation. Ophthalmology. 2021 09; 128(9):1355.
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Epidemiology of Scleritis in the United Kingdom From 1997 to 2018: Population-Based Analysis of 11 Million Patients and Association Between Scleritis and Infectious and Immune-Mediated Inflammatory Disease. Arthritis Rheumatol. 2021 07; 73(7):1267-1276.
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Bilateral Retinal Vasculitis as the First Presentation of Systemic Lupus Erythematosus. Am J Case Rep. 2021 May 03; 22:e930650.
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Tuberculous Scleritis and Multidrug Resistance. Ocul Immunol Inflamm. 2022 May 19; 30(4):915-924.
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Combination of Intravenous Methotrexate and Methylprednisolone Therapy in the Treatment of Severe Ocular Inflammatory Diseases. Ocul Immunol Inflamm. 2021 Nov 17; 29(7-8):1559-1563.
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Case 14-2020: A 37-Year-Old Man with Joint Pain and Eye Redness. N Engl J Med. 2020 04 30; 382(18):1750-1758.
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An Amelanotic Choroidal Mass in a Middle-aged Woman. JAMA Ophthalmol. 2019 12 01; 137(12):1452-1453.
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Comparison Between Methotrexate and Mycophenolate Mofetil Monotherapy for the Control of Noninfectious Ocular Inflammatory Diseases. Am J Ophthalmol. 2019 12; 208:68-75.