Ribonucleoprotein, U5 Small Nuclear
"Ribonucleoprotein, U5 Small Nuclear" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear RNA-protein complex that plays a role in RNA processing. In the nucleoplasm, the U5 snRNP along with U4-U6 snRNP preassemble into a single 25S particle that binds to the U1 and U2 snRNPs and the substrate to form SPLICEOSOMES.
MeSH Number(s)
D12.776.157.725.500.875.620
D12.776.664.962.500.875.620
Concept/Terms
Ribonucleoprotein, U5 Small Nuclear- Ribonucleoprotein, U5 Small Nuclear
- Small Nuclear Ribonucleoproteins, U5
- Ribonucleoproteins, Small, U5
- U5 snRNP
- U5 Small Nuclear Ribonucleoproteins
Below are MeSH descriptors whose meaning is more general than "Ribonucleoprotein, U5 Small Nuclear".
Below are MeSH descriptors whose meaning is more specific than "Ribonucleoprotein, U5 Small Nuclear".
This graph shows the total number of publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in Harvard Catalyst Profiles by year, and whether "Ribonucleoprotein, U5 Small Nuclear" was a major or minor topic of these publication.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2018 | 1 | 1 | 2 |
Below are the most recent publications written about "Ribonucleoprotein, U5 Small Nuclear" by people in Profiles.
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Novel De Novo EFTUD2 Mutations in 2 Cases With MFDM, Initially Suspected to Have Alternative Craniofacial Diagnoses. Cleft Palate Craniofac J. 2019 05; 56(5):674-678.
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Further evidence for the involvement of EFL1 in a Shwachman-Diamond-like syndrome and expansion of the phenotypic features. Cold Spring Harb Mol Case Stud. 2018 10; 4(5).
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EFTUD2 Is a Novel Innate Immune Regulator Restricting Hepatitis C Virus Infection through the RIG-I/MDA5 Pathway. J Virol. 2015 Jul; 89(13):6608-18.
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BS69/ZMYND11 reads and connects histone H3.3 lysine 36 trimethylation-decorated chromatin to regulated pre-mRNA processing. Mol Cell. 2014 Oct 23; 56(2):298-310.
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Mutational screening of splicing factor genes in cases with autosomal dominant retinitis pigmentosa. Mol Vis. 2014; 20:843-51.
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Splicing functions and global dependency on fission yeast slu7 reveal diversity in spliceosome assembly. Mol Cell Biol. 2013 Aug; 33(16):3125-36.
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SmD3 regulates intronic noncoding RNA biogenesis. Mol Cell Biol. 2012 Oct; 32(20):4092-103.
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Ubiquitin binding by a variant Jab1/MPN domain in the essential pre-mRNA splicing factor Prp8p. RNA. 2006 Feb; 12(2):292-302.
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Evidence that U5 snRNP recognizes the 3' splice site for catalytic step II in mammals. EMBO J. 1997 Aug 01; 16(15):4746-59.
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Identification of proteins that interact with exon sequences, splice sites, and the branchpoint sequence during each stage of spliceosome assembly. Mol Cell Biol. 1996 Jul; 16(7):3317-26.