Receptors, Purinergic P2X7
"Receptors, Purinergic P2X7" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purinergic P2X neurotransmitter receptor that plays a role in pain sensation signaling and regulation of inflammatory processes.
MeSH Number(s)
D12.776.157.530.400.400.750.700
D12.776.543.550.425.500.600.700
D12.776.543.585.400.500.600.700
D12.776.543.750.720.700.720.500.700
D12.776.543.750.810.720.500.700
Concept/Terms
Receptors, Purinergic P2X7- Receptors, Purinergic P2X7
- P2X7 Receptors, Purinergic
- Purinergic P2X7 Receptors
- P2X7 Purinoceptors
- Purinoceptors, P2X7
- P2X7 Receptor
- Receptor, P2X7
- Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7
- Purinoceptor P2Z
- P2Z, Purinoceptor
- P2X7 Purinoceptor
- Purinoceptor, P2X7
- P2Z Receptor
- Receptor, P2Z
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2X7".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
- Receptors, Purinergic P2X7 [D12.776.157.530.400.400.750.700]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.425]
- Ligand-Gated Ion Channels [D12.776.543.550.425.500]
- Receptors, Purinergic P2X [D12.776.543.550.425.500.600]
- Receptors, Purinergic P2X7 [D12.776.543.550.425.500.600.700]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
- Receptors, Purinergic P2X7 [D12.776.543.585.400.500.600.700]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
- Receptors, Purinergic P2X7 [D12.776.543.750.720.700.720.500.700]
- Receptors, Purinergic [D12.776.543.750.810]
- Receptors, Purinergic P2 [D12.776.543.750.810.720]
- Receptors, Purinergic P2X [D12.776.543.750.810.720.500]
- Receptors, Purinergic P2X7 [D12.776.543.750.810.720.500.700]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2X7".
This graph shows the total number of publications written about "Receptors, Purinergic P2X7" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Purinergic P2X7" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2003 | 0 | 3 | 3 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 4 | 4 |
| 2010 | 1 | 2 | 3 |
| 2011 | 3 | 4 | 7 |
| 2012 | 5 | 1 | 6 |
| 2013 | 4 | 1 | 5 |
| 2014 | 2 | 2 | 4 |
| 2015 | 2 | 3 | 5 |
| 2016 | 3 | 2 | 5 |
| 2017 | 2 | 1 | 3 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 2 | 0 | 2 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Purinergic P2X7" by people in Profiles.
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An integrated multi-omics analysis of sleep-disordered breathing traits implicates P2XR4 purinergic signaling. Commun Biol. 2023 01 31; 6(1):125.
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Prototypic P2X7 Receptor Agonist, BzATP, Induced the Expression of Unfolded Protein Response Genes in Human M1 Macrophages. Iran J Allergy Asthma Immunol. 2022 Feb 06; 21(1):73-80.
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P2X7R: pivotal player in sepsis-induced liver damage. Purinergic Signal. 2020 12; 16(4):473-474.
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P2RX7 inhibitor suppresses exosome secretion and disease phenotype in P301S tau transgenic mice. Mol Neurodegener. 2020 08 18; 15(1):47.
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Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells. Am J Physiol Cell Physiol. 2020 06 01; 318(6):C1123-C1135.
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P2X7 receptor activation increases expression of caveolin-1 and formation of macrophage lipid rafts, thereby boosting CD39 activity. J Cell Sci. 2020 03 06; 133(5).
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Increased P2X7 expression in the gastrointestinal tract and skin in a humanised mouse model of graft-versus-host disease. Clin Sci (Lond). 2020 01 31; 134(2):207-223.
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Targeting CD39 in Cancer Reveals an Extracellular ATP- and Inflammasome-Driven Tumor Immunity. Cancer Discov. 2019 12; 9(12):1754-1773.
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Association of P2RX7 functional variants with localized aggressive periodontitis. J Periodontal Res. 2020 Jan; 55(1):32-40.
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P2X7 PET Radioligand 18F-PTTP for Differentiation of Lung Tumor from Inflammation. J Nucl Med. 2019 07; 60(7):930-936.