Receptors, Purinergic P2X3
"Receptors, Purinergic P2X3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A purinergic P2X neurotransmitter receptor involved in sensory signaling of TASTE PERCEPTION, chemoreception, visceral distension, and NEUROPATHIC PAIN. The receptor comprises three P2X3 subunits. The P2X3 subunits are also associated with P2X2 RECEPTOR subunits in a heterotrimeric receptor variant.
MeSH Number(s)
D12.776.157.530.400.400.750.300
D12.776.543.550.425.500.600.300
D12.776.543.585.400.500.600.300
D12.776.543.750.720.700.720.500.300
D12.776.543.750.810.720.500.300
Concept/Terms
Receptors, Purinergic P2X3- Receptors, Purinergic P2X3
- P2X3 Receptors, Purinergic
- Purinergic P2X3 Receptors
- P2X3 Receptor
- Receptor, P2X3
- Purinergic Receptor P2X, Ligand-Gated Ion Channel, 3
- P2X3 Purinoceptor
- Purinoceptor, P2X3
Below are MeSH descriptors whose meaning is more general than "Receptors, Purinergic P2X3".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Membrane Transport Proteins [D12.776.157.530]
- Ion Channels [D12.776.157.530.400]
- Ligand-Gated Ion Channels [D12.776.157.530.400.400]
- Receptors, Purinergic P2X [D12.776.157.530.400.400.750]
- Receptors, Purinergic P2X3 [D12.776.157.530.400.400.750.300]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Ion Channels [D12.776.543.550.425]
- Ligand-Gated Ion Channels [D12.776.543.550.425.500]
- Receptors, Purinergic P2X [D12.776.543.550.425.500.600]
- Receptors, Purinergic P2X3 [D12.776.543.550.425.500.600.300]
- Membrane Transport Proteins [D12.776.543.585]
- Ion Channels [D12.776.543.585.400]
- Ligand-Gated Ion Channels [D12.776.543.585.400.500]
- Receptors, Purinergic P2X [D12.776.543.585.400.500.600]
- Receptors, Purinergic P2X3 [D12.776.543.585.400.500.600.300]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P2 [D12.776.543.750.720.700.720]
- Receptors, Purinergic P2X [D12.776.543.750.720.700.720.500]
- Receptors, Purinergic P2X3 [D12.776.543.750.720.700.720.500.300]
- Receptors, Purinergic [D12.776.543.750.810]
- Receptors, Purinergic P2 [D12.776.543.750.810.720]
- Receptors, Purinergic P2X [D12.776.543.750.810.720.500]
- Receptors, Purinergic P2X3 [D12.776.543.750.810.720.500.300]
Below are MeSH descriptors whose meaning is more specific than "Receptors, Purinergic P2X3".
This graph shows the total number of publications written about "Receptors, Purinergic P2X3" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Purinergic P2X3" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 1 | 2 |
| 2014 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Purinergic P2X3" by people in Profiles.
-
The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug; 7(4).
-
Regulatory function of praja ring finger ubiquitin ligase 2 mediated by the P2rx3/P2rx7 axis in mouse hippocampal neuronal cells. Am J Physiol Cell Physiol. 2020 06 01; 318(6):C1123-C1135.
-
Localized inhibition of P2X7R at the spinal cord injury site improves neurogenic bladder dysfunction by decreasing urothelial P2X3R expression in rats. Life Sci. 2017 Feb 15; 171:60-67.
-
Adenosine triphosphate drives head and neck cancer pain through P2X2/3 heterotrimers. Acta Neuropathol Commun. 2014 Jun 05; 2:62.
-
Optical control of trimeric P2X receptors and acid-sensing ion channels. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):521-6.
-
The mechanism of functional up-regulation of P2X3 receptors of trigeminal sensory neurons in a genetic mouse model of familial hemiplegic migraine type 1 (FHM-1). PLoS One. 2013; 8(4):e60677.
-
Tlx3 and Runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11; 32(28):9706-15.
-
Residual chemoresponsiveness to acids in the superior laryngeal nerve in "taste-blind" (P2X2/P2X3 double-KO) mice. Chem Senses. 2012 Jul; 37(6):523-32.
-
Defining protein expression in the urothelium: a problem of more than transitional interest. Am J Physiol Renal Physiol. 2011 Nov; 301(5):F932-42.
-
Identification of P2X3 and P2X7 purinergic receptors activated by ATP in rat lacrimal gland. Invest Ophthalmol Vis Sci. 2011 May 17; 52(6):3254-63.